Evidence to Support the Role of HLA-G5 in Allograft Acceptance through Induction of Immunosuppressive/ Regulatory T Cells1

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Immunology

• Publication date

  2006-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.4049/jimmunol.176.5.3266PMID 16493088
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tolerization of dendritic cells by HLA‐G

  2005cited by this paper
• Novel phenotypes and migratory properties distinguish memory CD4 T cell subsets in lymphoid and lung tissue

  2005cited by this paper
• HLA‐G up‐regulates ILT2, ILT3, ILT4, and KIR2DL4 in antigen presenting cells, NK cells, and T cells

  2005cited by this paper
• Regulatory T cells and mechanisms of immune system control

  2004cited by this paper
• HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4+ T cells.

  2004cited by this paper
• Alloreactive CD4+ and CD8+ T cells express the immunotolerant HLA‐G molecule in mixed lymphocyte reactions: in vivo implications in transplanted patients

  2004influential reference
• Routes to transplant tolerance versus rejection; the role of cytokines.

  2004cited by this paper
• Erythroblasts secrete the nonclassical HLA-G molecule from primitive to definitive hematopoiesis.

  2004cited by this paper
• Immune regulation by CD4+CD25+ regulatory T cells: implications for transplantation tolerance.

  2003cited by this paper
• The complementary roles of deletion and regulation in transplantation tolerance

  2003cited by this paper
• Detection of HLA-G in serum and graft biopsy associated with fewer acute rejections following combined liver-kidney transplantation: possible implications for monitoring patients.

  2003influential reference
• Soluble HLA‐A,‐B,‐C and ‐G molecules induce apoptosis in T and NK CD8+ cells and inhibit cytotoxic T cell activity through CD8 ligation

  2003cited by this paper
• Incidence of Renal and Liver Rejection and Patient Survival Rate Following Combined Liver and Kidney Transplantation

  2003cited by this paper
• Mobilizing dendritic cells for tolerance by engagement of immune inhibitory receptors for HLA-G.

  2003cited by this paper
• HLA-G molecules: from maternal-fetal tolerance to tissue acceptance.

  2003cited by this paper
• Human leukocyte antigen-G (HLA-G) expression in biliary epithelial cells is associated with allograft acceptance in liver-kidney transplantation.

  2003influential reference
• Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

  2003cited by this paper
• HLA‐G in Transplantation: A Relevant Molecule for Inhibition of Graft Rejection?

  2003cited by this paper
• Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules.

  2003cited by this paper
• Complexes of HLA-G Protein on the Cell Surface Are Important for Leukocyte Ig-Like Receptor-1 Function1

  2003cited by this paper
• IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function.

  2003cited by this paper
• MICA triggering signal for NK cell tumor lysis is counteracted by HLA‐G1‐mediated inhibitory signal

  2002cited by this paper
• Human Leukocyte Antigen-G Expression After Heart Transplantation Is Associated With a Reduced Incidence of Rejection

  2002cited by this paper
• HLA‐G inhibits the functions of murine dendritic cells via the PIR‐B immune inhibitory receptor

  2002influential reference
• Soluble HLA-G protein secreted by allo-specific CD4+ T cells suppresses the allo-proliferative response: A CD4+ T cell regulatory mechanism

  2001influential reference
• Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

  2001cited by this paper
• On the ontogeny and physiology of regulatory T cells

  2001cited by this paper
• HLA-G1 co-expression boosts the HLA class I-mediated NK lysis inhibition.

  2001cited by this paper
• HLA-G2, -G3, and -G4 Isoforms Expressed as Nonmature Cell Surface Glycoproteins Inhibit NK and Antigen-Specific CTL Cytolysis1

  2001influential reference
• Implication of HLA-G molecule in heart-graft acceptance.

  2000cited by this paper
• HLA-G, -E, -F preworkshop: tools and protocols for analysis of non-classical class I genes transcription and protein expression.

  2000influential reference
• Cutting Edge: Soluble HLA-G1 Triggers CD95/CD95 Ligand-Mediated Apoptosis in Activated CD8+ Cells by Interacting with CD81

  2000cited by this paper
• Structural Relatedness of Distinct Determinants Recognized by Monoclonal Antibody TP25.99 on β2-Microglobulin-Associated and β2-Microglobulin-Free HLA Class I Heavy Chains1

  2000cited by this paper
• Inhibitory receptors sensing HLA-G1 molecules in pregnancy: decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor.

  1999cited by this paper
• HLA-G isoforms produced by placental cytotrophoblasts and found in amniotic fluid are due to unusual glycosylation.

  1998cited by this paper
• Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules.

  1998influential reference
• A Common Inhibitory Receptor for Major Histocompatibility Complex Class I Molecules on Human Lymphoid and Myelomonocytic Cells

  1997cited by this paper
• Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis.

  1997cited by this paper

• Soluble Mediators Related to Immunity in Pregnancy‐Related Disorders: Roles of Immune Checkpoints, Platelet Activation Markers, TNF Receptors, and NETs

  2026cites this paper
• Harnessing the potential of HLA-G in cancer therapy: advances, challenges, and prospects

  2024cites this paper
• HLA-G can be transfered via trogocytosis from leukemic cells to T cells in chronic lymphocytic leukemia.

  2024cites this paper
• Characterization of Amnion-Derived Membrane for Clinical Wound Applications

  2024cites this paper
• Human leukocyte immunoglobulin-like receptors in health and disease

  2023cites this paper
• Soluble HLA-G levels in heart transplant recipients: Dynamics and correlation with clinical outcomes.

  2022cites this paper
• New markers for predictions of acute and chronic rejection and graft outcomes in kidney transplant recipients; HLA-G gene 3'UTR 14bp polymorphism and sHLA-G.

  2021cites this paper
• HLA-G 14 bp In/Del and +3142 C/G genotypes are differentially expressed between patients with grade IV gliomas and controls

  2020cites this paper
• Structural Modeling and Molecular Dynamics of the Immune Checkpoint Molecule HLA-G

  2020cites this paper
• Amnion-Derived Multipotent Progenitor Cells Suppress Experimental Optic Neuritis and Myelitis

  2020cites this paper
• Therapeutic potential of mesenchymal stem cells in treating both types of diabetes mellitus and associated diseases

  2020cites this paper
• Human leukocyte antigen-G upregulates immunoglobulin-like transcripts and corrects dysfunction of immune cells in immune thrombocytopenia

  2020cites this paper
• Immunomodulatory Properties of Amniotic Membrane Derivatives and Their Potential in Regenerative Medicine

  2020cites this paper
• High level of soluble human leukocyte antigen (HLA)-G at beginning of pregnancy as predictor of risk of malaria during infancy

  2019cites this paper
• The Effect of Mesenchymal Stem Cells on the Expression of IDO and Qa2 Molecules in Dendritic Cells

  2019cites this paper
• The Dual Nature of Mesenchymal Stem Cells (MSCs): Yin and Yang of the Inflammatory Process

  2019cites this paper
• Donor derived HLA-G polymorphisms have a significant impact on acute rejection in kidney transplantation.

  2019cites this paper
• The Immunomodulatory Properties of Amniotic Cells

  2018cites this paper
• The HLA‐G 14 bp insertion/deletion polymorphism and its association with soluble HLA‐G levels in women with recurrent miscarriages

  2018cites this paper
• Immunological biomarkers of tolerance in human kidney transplantation: An updated literature review

  2018cites this paper
• T cell infiltration into Ewing sarcomas is associated with local expression of immune-inhibitory HLA-G

  2017cites this paper
• Precise immune tolerance for hPSC derivatives in clinical application.

  2017cites this paper
• Circulating and renal expression of HLA-G prevented chronic renal allograft dysfunction in Japanese recipients

  2017cites this paper
• Concise Review: Fetal Membranes in Regenerative Medicine: New Tricks from an Old Dog?

  2017cites this paper
• New Developments in HLA-G in Cardiac Transplantation.

  2016cites this paper
• 14-bp ins/del polymorphism and +3142C>G SNP of the HLA-G gene have a significant impact on acute rejection after liver transplantation.

  2016cites this paper
• Peripheral phenotype and gene expression profiles of combined liver–kidney transplant patients

  2016cites this paper
• What is wrong with the regulatory T cells and foetomaternal tolerance in women with recurrent miscarriages?

  2016cites this paper
• Recent Advances in Our Understanding of HLA-G Biology: Lessons from a Wide Spectrum of Human Diseases

  2016cites this paper
• Differential expression of HLA-G and ILT-2 receptor in human tuberculosis: Localized versus disseminated disease.

  2016cites this paper
• Recombinant HLA-G as Tolerogenic Immunomodulant in Experimental Small Bowel Transplantation

  2016cites this paper
• The Potential of HLA-G-Bearing Extracellular Vesicles as a Future Element in HLA-G Immune Biology

  2016cites this paper
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  2016cites this paper
• Association of Human Leukocyte Antigen-G Polymorphisms and Clinical Outcomes Post-Transplantation

  2016cites this paper
• Human leukocyte antigen G and renal allograft transplant.

  2015cites this paper
• HLA-G: An Immune Checkpoint Molecule.

  2015cites this paper
• Clinical correlates of human leucocyte antigen (HLA)‐G in systemic sclerosis1

  2015cites this paper
• Role of HLA‐G as a Predictive Marker of Low Risk of Chronic Rejection in Lung Transplant Recipients: A Clinical Prospective Study

  2015cites this paper
• HLA-G : de la tolérance fœto-maternelle à l’acceptation d’organe

  2014cites this paper
• HLA-G as a Tolerogenic Molecule in Transplantation and Pregnancy

  2014cites this paper
• Binding of HLA-G to ITIM-Bearing Ig-like Transcript 2 Receptor Suppresses B Cell Responses

  2014influential citation
• HLA-G Dimers in the Prolongation of Kidney Allograft Survival

  2014cites this paper
• HLA-G Molecules in Autoimmune Diseases and Infections

  2014cites this paper
• Association of Soluble HLA-G with Acute Rejection Episodes and Early Development of Bronchiolitis Obliterans in Lung Transplantation

  2014cites this paper
• The emerging role of soluble HLA-G in the control of chemotaxis.

  2014cites this paper
• [Trophoblast: conductor of the maternal immune tolerance].

  2014influential citation
• The Dual Role of HLA-G in Cancer

  2014cites this paper
• In vivo evidence that secretion of HLA‐G by immunogenic tumor cells allows their evasion from immunosurveillance

  2014cites this paper
• Neutrophil Gelatinase-Associated Lipocalin Increases HLA-G+/FoxP3+ T-Regulatory Cell Population in an In Vitro Model of PBMC

  2014cites this paper
• Impact of human leukocyte antigen molecules E, F, and G on the outcome of transplantation.

  2014cites this paper
• The role of the atypical chemokine receptor D6 in the placenta

  2014cites this paper
• Biomarkers of Operational Tolerance in Liver Transplantation

  2014cites this paper
• [HLA-G: from feto-maternal tolerance to organ acceptance].

  2014cites this paper
• Responses2 Receptor Suppresses B Cell Binding of HLA-G to ITIM-Bearing Ig-like

  2014cites this paper
• HLA-G Expression as a Prognostic Indicator in B-Cell Chronic Lymphocytic Leukemia

  2014cites this paper
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  2014cites this paper
• HLA-dependent tumour development: a role for tumour associate macrophages?

  2013cites this paper
• Comparison Between an Artificial Neural Network and Logistic Regression in Predicting Long Term Kidney Transplantation Outcome

  2013cites this paper
• Preterm human amnion epithelial cells have limited reparative potential.

  2013cites this paper
• Human Tolerance Maternal Acceptance of the Fetus: True

  2013cites this paper
• HLA-G expression in the peripheral blood of live kidney transplant recipients.

  2013cites this paper
• Post-transplant increase in soluble human leukocyte antigen-G associated with non-severe cardiac allograft vasculopathy.

  2013cites this paper
• Amnion‐Derived Multipotent Progenitor Cells Support Allograft Tolerance Induction

  2013cites this paper
• A study of the variation of leukocyte immunoglobulin-like receptors on antigen-presenting cells

  2013cites this paper
• molecule Beyond the increasing complexity of the immunomodulatory HLA-G

  2013cites this paper
• Human leucocyte antigen‐G: expression and function in airway allergic disease

  2012cites this paper
• Influência dos genes HLA classe I na progressão para a Aids em indivíduos HIV positivos

  2012cites this paper
• cells The tolerogenic interplay(s) among HLA-G, myeloid APCs, and regulatory

  2012cites this paper
• Assessment of different biomarkers provides valuable diagnostic standards in the evaluation of the risk of acute rejection.

  2012cites this paper
• Pharmacogenetic markers of response to drugs used in the management of Inflammatory Bowel Disease

  2012cites this paper
• Nanoparticles targeting HLA-G for gene therapy in cancer

  2012cites this paper
• The immunosuppressive molecule HLA-G and its clinical implications

  2012cites this paper
• Maternal soluble human leukocyte antigen-G levels in pregnancies complicated by foetal intrauterine growth restriction with and without preeclampsia.

  2012cites this paper
• Identification of a novel HLA-G+ regulatory population in blood: expansion after allogeneic transplantation and de novo HLA-G expression at graft-versus-host disease sites

  2012cites this paper
• Immune characterization of mesenchymal stem cells in human umbilical cord Wharton's jelly and derived cartilage cells.

  2012cites this paper
• The role of the HLA-G gene and molecule on the clinical expression of rheumatologic diseases.

  2012cites this paper
• Association of HLA-G polymorphisms with nasopharyngeal carcinoma risk and clinical outcome.

  2011cites this paper
• The tolerogenic interplay(s) among HLA-G, myeloid APCs, and regulatory cells.

  2011cites this paper
• Association of HLA-G Low Expressor Genotype with Severe Acute Graft-Versus-Host Disease after Sibling Bone Marrow Transplantation

  2011cites this paper
• Role of HLA-G in tumor escape through expansion of myeloid-derived suppressor cells and cytokinic balance in favor of Th2 versus Th1/Th17.

  2011cites this paper
• Lymphocyte Cell-Cycle Inhibition by HLA-G Is Mediated by Phosphatase SHP-2 and Acts on the mTOR Pathway

  2011cites this paper
• Emerging topics and new perspectives on HLA-G

  2011cites this paper
• Dynamic Expression of Qa-2 during Acute Graft Rejection

  2011cites this paper
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  2011cites this paper
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  2011cites this paper
• HLA-G regulators in cancer medicine: an outline of key requirements

  2011cites this paper
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  2011cites this paper
• Frequency of HLA-G exon 8 polymorphisms and kidney allograft outcome in Iranian population

  2011cites this paper
• The importance of HLA-G expression in embryos, trophoblast cells, and embryonic stem cells

  2011cites this paper
• HLA-G in organ transplantation: towards clinical applications

  2011cites this paper
• The role of HLA-G in immunity and hematopoiesis

  2011cites this paper
• Inhibition of human Vγ9Vδ2 T-cell antitumoral activity through HLA-G: implications for immunotherapy of cancer

  2011cites this paper
• [ILT3+/ILT4+ tolerogenic dendritic cells and their influence on allograft survival].

  2011cites this paper
• Papel de las células dendríticas tolerogénicas ILT3+/ILT4+ en la respuesta inmunitaria a trasplante de órganos y tejidos

  2011cites this paper
• Tolerância operacional no transplante renal humano: repertório de linfócitos B e de alo e autoanticorpos

  2011cites this paper
• Expression of Soluble HLA-G Identifies Favorable Outcomes in Liver Transplant Recipients

  2010influential citation
• Mechanisms of cellular communication through intercellular protein transfer

  2010cites this paper
• Tumor-specific upregulation of human leukocyte antigen-G expression in bladder transitional cell carcinoma.

  2010cites this paper
• Pediatric renal transplantation: an overview and update

  2010cites this paper
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  2010cites this paper