Autologous or allogeneic bone marrow transplantation compared with intensive chemotherapy in acute myelogenous leukemia. European Organization for Research and Treatment of Cancer (EORTC) and the Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) Leukemia Cooperative Groups.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  New England Journal of Medicine

• Publication date

  1995-01-26

• Fields of study

  Medicine

• Identifiers
  DOI 10.1056/NEJM199501263320403PMID 7808487
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B.

  1994cited by this paper
• Effect of all transretinoic acid in newly diagnosed acute promyelocytic leukemia. Results of a multicenter randomized trial. European APL 91 Group.

  1993cited by this paper
• Autologous marrow transplantation for patients with acute myeloid leukemia in untreated first relapse or in second complete remission.

  1993cited by this paper
• Effect of all transretinoic acid in newly diagnosed acute promyelocytic leukemia. Results of a multicenter randomized trial. European APL 91 Group

  1993cited by this paper
• Treatment of the newly diagnosed adult with de novo acute myeloid leukemia.

  1993cited by this paper
• Varying intensity of postremission therapy in acute myeloid leukemia.

  1992cited by this paper
• Autologous bone marrow transplantation vs intensive chemotherapy in first complete remission: interim results of GOELAM study in AML.

  1992cited by this paper
• Allogeneic marrow transplantation during untreated first relapse of acute myeloid leukemia.

  1992cited by this paper
• Bone marrow transplantation versus high-dose cytarabine-based consolidation chemotherapy for acute myelogenous leukemia in first remission.

  1992cited by this paper
• Immunotherapy of leukemia.

  1992cited by this paper
• Autologous bone marrow transplantation for acute myeloblastic leukemia in Europe : further evidence of the role of marrow purging by mafosfamide

  1991cited by this paper
• Double intensive consolidation chemotherapy in adult acute myeloid leukemia.

  1991cited by this paper
• Bone marrow transplantation or chemotherapy as post-remission treatment of adult acute myelogenous leukemia

  1991cited by this paper
• Autologous bone marrow transplantation for acute myeloblastic leukemia in Europe: further evidence of the role of marrow purging by mafosfamide. European Co-operative Group for Bone Marrow Transplantation (EBMT).

  1991cited by this paper
• The value of BMT in AML patients in first remission A statistician's view-point

  1991cited by this paper
• Double intensive consolidation chemotherapy in adult acute myeloid leukemia.

  1991cited by this paper
• Graft-versus-leukemia reactions after bone marrow transplantation.

  1990cited by this paper
• High-dose chemotherapy and autologous bone marrow transplantation in acute myeloid leukemia.

  1990cited by this paper
• Autologous bone marrow transplantation in acute myeloid leukemia in first remission: results of a Dutch prospective study.

  1990cited by this paper
• Autologous bone marrow transplantation for acute myelocytic leukemia in first remission: a European survey of the role of marrow purging.

  1990cited by this paper
• Alternating v repeated postremission treatment in adult acute myelogenous leukemia: a randomized phase III study (AML6) of the EORTC Leukemia Cooperative Group.

  1989cited by this paper
• Marrow transplantation in acute nonlymphocytic leukemia.

  1989cited by this paper
• High-dose cytarabine and daunorubicin as consolidation therapy for acute myeloid leukemia in first remission: long-term follow-up and results.

  1989cited by this paper
• Transplant or chemotherapy in acute myelogenous leukaemia

  1989cited by this paper
• Treatment of acute myelogenous leukemia. An EBMT-EORTC retrospective analysis of chemotherapy versus allogeneic or autologous bone marrow transplantation.

  1989cited by this paper
• Comparison of allogeneic or autologous bone marrow transplantation and chemotherapy in patients with acute myeloid leukaemia in first remission: a prospective controlled trial

  1989cited by this paper
• A comparison of marrow transplantation with chemotherapy for adults with acute leukemia of poor prognosis in first complete remission.

  1988cited by this paper
• Chemotherapy v marrow transplantation for adults with acute nonlymphocytic leukemia: a five-year follow-up.

  1988cited by this paper
• Chemotherapy v marrow transplantation for adults with acute nonlymphocytic leukemia: a five-year follow-up

  1988cited by this paper
• Short-term therapy for acute myelogenous leukemia.

  1988cited by this paper
• Cytogenetic pattern in acute myelogenous leukemia: a major reproducible determinant of outcome.

  1988cited by this paper
• Autologous unpurged bone marrow transplantation for acute non-lymphoblastic leukaemia in first complete remission.

  1988cited by this paper
• Allogeneic transplantation versus intensive chemotherapy in first-remission acute leukemia: is there a "best choice"?

  1988cited by this paper
• Prolonged unmaintained remission after intensive consolidation therapy in adult acute nonlymphocytic leukemia.

  1987cited by this paper
• The treatment of acute non-lymphoblastic leukemia by allogeneic marrow transplantation.

  1987cited by this paper
• Intensive remission consolidation therapy in the treatment of acute nonlymphocytic leukemia.

  1987cited by this paper
• Cerebellar toxicity with high-dose cytosine arabinoside.

  1987cited by this paper
• Autologous bone marrow transplantation following high dose chemotherapy for the treatment of adult patients with acute myeloid leukaemia

  1986cited by this paper
• Treatment of acute myelogenous leukemia. A prospective controlled trial of bone marrow transplantation versus consolidation chemotherapy.

  1985cited by this paper
• Cancer Clinical Trials: Methods and Practice.

  1985cited by this paper
• Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group.

  1985cited by this paper
• Treatment of Acute Myelogenous Leukemia: A Prospective Controlled Trial of Bone Marrow Transplantation Versus Consolidation Chemotherapy

  1985cited by this paper
• Intensified induction and consolidation with or without maintenance chemotherapy for acute myeloid leukemia (AML): two multicenter studies of the German AML Cooperative Group.

  1985cited by this paper
• A critical comparison of allogeneic bone marrow transplantation and conventional chemotherapy as treatment for acute nonlymphocytic leukemia.

  1984cited by this paper
• A randomized study of the efficacy of consolidation therapy in adult acute nonlymphocytic leukemia.

  1984cited by this paper
• Transplantation of unpurged autologous bone-marrow in acute myeloid leukaemia in first remission.

  1984cited by this paper
• Marrow transplantation for acute nonlymphocytic leukemia after treatment with busulfan and cyclophosphamide.

  1983cited by this paper
• Use of Ranks in One-Criterion Variance Analysis

  1952cited by this paper

• Interleukin-15 and innate effector cells as predictors of outcome in allogeneic hematopoietic cell transplantation

  2026cites this paper
• Safety and Efficacy of High-Dose Chemotherapy with TreoMel 200 vs. TreoMel 140 in Acute Myeloid Leukemia Patients Undergoing Autologous Stem Cell Transplantation

  2024cites this paper
• Allogeneic stem cell transplantation against aggressive lymphomas: graft-versus-lymphoma effects in peripheral T-cell lymphoma and diffuse large B-cell lymphoma after myeloablative conditioning

  2024cites this paper
• CACA guidelines for holistic integrative management of adult acute myeloid leukemia

  2024cites this paper
• Reduced Intensity transplantation vs chemotherapy in CR1. A prospective, pseudorandomized study in 50–70 year old AML patients

  2024cites this paper
• Microcosting analysis of haematopoietic stem cell transplantation and chemotherapy with intermediate doses of cytarabine in the treatment of acute myeloid leukaemia

  2024cites this paper
• Autologous stem cell transplantation in adult patients with intermediate-risk acute myeloid leukemia in first complete remission and no detectable minimal residual disease. A comparative retrospective study with haploidentical transplants of the global committee and the ALWP of the EBMT

  2023cites this paper
• [Chinese guidelines for diagnosis and treatment of adult acute myeloid leukemia (not APL) (2023)].

  2023cites this paper
• Pediatric Autologous Hematopoietic Stem Cell Transplantation: Safety, Efficacy, and Patient Outcomes. Literature Review

  2023cites this paper
• Allogeneic transplantation in acute myelogenous leukemia: a comprehensive single institution's experience

  2023cites this paper
• Hematopoietic stem cell transplantation in Zagreb: the first 40 years

  2023cites this paper
• Risk of subsequent malignant neoplasms following hematopoietic stem cell transplantation with total body irradiation or total marrow irradiation: insights from early follow-up.

  2022cites this paper
• Autologous stem cell transplantation in favorable-risk acute myeloid leukemia: single-center experience and current challenges

  2022cites this paper
• Challenges in Cell Fate Acquisition to Scid-Repopulating Activity from Hemogenic Endothelium of hiPSCs Derived from AML Patients Using Forced Transcription Factor Expression

  2022cites this paper
• Antineoplastic activity of biogenic silver and gold nanoparticles to combat leukemia: Beginning a new era in cancer theragnostic

  2022cites this paper
• Genome Editing of Pluripotent Stem Cells for Adoptive and Regenerative Cell Therapies

  2022cites this paper
• Autologous hematopoietic stem cell transplantation followed by interleukin-2 for adult acute myeloid leukemia patients with favorable or intermediate risk after complete remission

  2022cites this paper
• Medico Oncology (2020) VOL:PAGES -

  2021influential citation
• Optimizing autologous hematopoietic stem cell transplantation for acute leukemia

  2021cites this paper
• Studentized permutation method for comparing two restricted mean survival times with small sample from randomized trials

  2021cites this paper
• 中国成人急性髓系白血病（非急性早幼粒细胞白血病）诊疗指南（2021年版）

  2021cites this paper
• History and Development of Autologous Stem Cell Transplantation for Acute Myeloid Leukemia

  2021cites this paper
• Association Between Measurable Residual Disease in Patients With Intermediate-Risk Acute Myeloid Leukemia and First Remission, Treatment, and Outcomes

  2021cites this paper
• A phase II study of azacitidine in combination with granulocyte-macrophage colony-stimulating factor as maintenance treatment, after allogeneic blood or marrow transplantation in patients with poor-risk acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)

  2021cites this paper
• Safety and tolerability of lenalidomide maintenance in post-transplant acute myeloid leukemia and high-risk myelodysplastic syndrome

  2021cites this paper
• In Vitro Generated Dendritic Cells of Leukemic Origin Predict Response to Allogeneic Stem Cell Transplantation in Patients With AML and MDS

  2021cites this paper
• The evolving concept of indications for allogeneic hematopoietic cell transplantation during first complete remission of acute myeloid leukemia

  2021cites this paper
• Acute Myeloid Leukemia

  2020cites this paper
• Survival Improvement over Time of 960 s-AML Patients Included in 13 EORTC-GIMEMA-HOVON Trials

  2020cites this paper
• Designing clinical trials with (restricted) mean survival time endpoint: Practical considerations

  2020cites this paper
• The Role of Stem Cell Transplant in the Therapy of Acute Myeloid Leukemia (AML)

  2020cites this paper
• Allogeneic Haemopoietic Stem Cell Transplantation

  2020cites this paper
• Estimation of radiation-induced organ-specific secondary solid tumor occurrence rates with total body irradiation and total marrow irradiation treatments.

  2020cites this paper
• Comparative Efficacy and Clinical Outcomes of Haploidentical Stem Cell Transplantation to Other Stem Sources for Treatment in Acute Myeloid Leukemia and Myelodysplastic Syndrome Patients: A Systematic Review and Meta-Analysis

  2020cites this paper
• Sequential treatment with FLAG-IDA/treosulfan conditioning regimen for patients with active acute myeloid leukemia

  2020cites this paper
• Long-term follow-up of a trial comparing post-remission treatment with autologous or allogeneic bone marrow transplantation or intensive chemotherapy in younger acute myeloid leukemia patients

  2020cites this paper
• Autologous Hematopoietic Stem Cell Transplantation in Acute Myelogenous Leukemia.

  2019cites this paper
• Hématologie et thérapie cellulaire. Historique de l’autogreffe de cellules souches hématopoïétiques : rôle actuel en hématologie. Nouveautés pour le traitement des leucémies aiguës myéloblastiques de l’adulte

  2019cites this paper
• Unrelated donor hematopoietic stem cell transplantation for pediatric de novo acute myeloid leukemia with intermediate‐ or high‐risk cytogenetics

  2019cites this paper
• Autologous hematopoietic cell transplantation for AML in first remission - An abandoned practice or promising approach?

  2019cites this paper
• Maintenance therapy in AML: The past, the present and the future

  2019cites this paper
• Autologous hematopoietic cell transplantation for acute myeloid leukemia in adults: 25 years of experience in Japan

  2019cites this paper
• Daunorubicin and cytarabine for certain types of poor-prognosis acute myeloid leukemia: a systematic literature review

  2019cites this paper
• A systematic review of patient reported outcomes in phase II or III clinical trials of myelodysplastic syndromes and acute myeloid leukemia.

  2018cites this paper
• Randomized clinical trials comparing autologous stem cell transplantation and chemotherapy or no further therapy

  2018cites this paper
• Comparison of conditioning regimens for autologous stem cell transplantation in children with acute myeloid leukemia: A nationwide retrospective study in Japan

  2018cites this paper
• ADAMTS-13 activity reduction in plasma of acute myeloid leukemia predicts poor prognosis after bone marrow transplantation

  2018cites this paper
• Bespoke cell therapy manufacturing platforms

  2018cites this paper
• Trasplante de células madre hematopoyéticas en pacientes pediátricos con diagnóstico de neoplasias mieloides, experiencia en 15 años

  2018cites this paper
• Adenovirusinfektionen nach hämatopoetischer Stammzelltransplantation im Kindesalter

  2018cites this paper
• Sequential HLA‐haploidentical transplantation utilizing post‐transplantation cyclophosphamide for GvHD prophylaxis in high‐risk and relapsed/refractory AML/MDS

  2018cites this paper
• Potential Usefulness of Early Potassium Supplementation for Preventing Severe Hypokalemia Induced by Liposomal Amphotericin B in Hematologic Patients: A Retrospective Study.

  2018cites this paper
• Iron overload is correlated with impaired autologous stem cell mobilization and survival in acute myeloid leukemia

  2018cites this paper
• Epidemiological studies in de novo and secondary acute leukemia

  2018cites this paper
• Prospective randomization of post-remission therapy comparing autologous peripheral blood stem cell transplantation versus high-dose cytarabine consolidation for acute myelogenous leukemia in first remission

  2018cites this paper
• Prognostic role of KIR genes and HLA-C after hematopoietic stem cell transplantation in a patient cohort with acute myeloid leukemia from a consanguineous community

  2018cites this paper
• Outcomes of Intermediate Risk Karyotype Acute Myeloid Leukemia in First Remission Undergoing Autologous Stem Cell Transplantation Compared With Allogeneic Stem Cell Transplantation and Chemotherapy Consolidation: A Retrospective, Propensity‐score Adjusted Analysis

  2018cites this paper
• Hematopoietic stem cell transplantation for adult patients with isolated NPM1 mutated acute myeloid leukemia in first remission

  2018cites this paper
• GM-CSF FOR INDUCTION OF ACUTE MYELOID LEUKEMIA

  2017cites this paper
• Clinical Outcome of Autologous Hematopoietic Cell Transplantation in Adult Patients with Acute Myeloid Leukemia: Who May Benefit from Autologous Hematopoietic Cell Transplantation?

  2017cites this paper
• Efficacy and safety of different doses of cytarabine in consolidation therapy for adult acute myeloid leukemia patients: a network meta-analysis

  2017cites this paper
• Genomics of Acute Myeloid Leukemia

  2017cites this paper
• Autologous hematopoietic stem cell transplantation for acute myeloid leukemia - single center experience.

  2017cites this paper
• Comparison of Autologous and Unrelated Transplants for Cytogenetically Normal Acute Myelogenous Leukemia.

  2017cites this paper
• Chapter 5 References

  2017cites this paper
• T-cell replete peripheral blood haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide results in outcomes similar to traditionally matched donors in active disease acute myeloid leukemia

  2017cites this paper
• Allogeneic Hematopoietic Stem Cell Transplantation in patients with Acute Myeloid Leukemia : a personalized approach

  2017cites this paper
• T Cell-Replete Peripheral Blood Haploidentical Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide Results in Outcomes Similar to Transplantation from Traditionally Matched Donors in Active Disease Acute Myeloid Leukemia.

  2017cites this paper
• Pre-transplant Quantitative Determination of NPM1 Mutation Significantly Predicts Outcome of AIlogeneic Hematopoietic Stem Cell Transplantation in Patients with Normal Karyotype AML in Complete Remission.

  2016cites this paper
• Haematological recovery in poor and good haematopoietic stem cell mobilisers

  2016cites this paper
• Increasing intensity of therapies assigned at diagnosis does not improve survival of adults with acute myeloid leukemia

  2016cites this paper
• Lived Experience Among Patients With Allogeneic Stem Cell Transplantation: A Single Center Experience

  2016cites this paper
• Risk factors for relapse after allogeneic transplantation in acute myeloid leukemia

  2016cites this paper
• Comparable outcomes between autologous and allogeneic transplant for adult acute myeloid leukemia in first CR

  2016cites this paper
• Autologous stem cell transplantation as a consolidation therapy in acute myeloid leukemia patients

  2016cites this paper
• Matched and mismatched unrelated donor compared to autologous stem cell transplantation for acute myeloid leukemia in first complete remission: a retrospective, propensity score-weighted analysis from the ALWP of the EBMT

  2016cites this paper
• Reduced-intensity Allogeneic Transplantation Regimens

  2016cites this paper
• Long-term outcomes of patients with intermediate-risk acute myeloid leukemia treated with autologous hematopoietic cell transplant in first complete remission

  2016cites this paper
• Radionuclide Therapy of Leukemias and Multiple Myeloma

  2016cites this paper
• Acute myeloid leukemia—Major progress over four decades and glimpses into the future

  2016cites this paper
• FLAMSA reduced‐intensity conditioning is equally effective in AML patients with primary induction failure as well as in first or second complete remission

  2016cites this paper
• Improved Survival With Integration of Chinese Herbal Medicine Therapy in Patients With Acute Myeloid Leukemia: A Nationwide Population-Based Cohort Study

  2016cites this paper
• Multigene Measurable Residual Disease Assessment Improves Acute Myeloid Leukemia Relapse Risk Stratification in Autologous Hematopoietic Cell Transplantation.

  2016cites this paper
• Outcome of children with high-risk acute myeloid leukemia given autologous or allogeneic hematopoietic cell transplantation in the aieop AML-2002/01 study.

  2015cites this paper
• Review of the Results of WT1 Peptide Vaccination Strategies for Myelodysplastic Syndromes and Acute Myeloid Leukemia from Nine Different Studies

  2015influential citation
• Progress in acute myeloid leukemia.

  2015cites this paper
• Is allogeneic transplantation really the best treatment for FLT3/ITD‐positive acute myeloid leukemia? A systematic review

  2015cites this paper
• Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Intermediate-Risk Acute Myeloid Leukemia Adult Patients in First Complete Remission: A Meta-Analysis of Prospective Studies

  2015cites this paper
• Autologous stem cell transplantation for adult acute leukemia in 2015: time to rethink? Present status and future prospects

  2015cites this paper
• Alternative Donor Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid Leukemia.

  2015cites this paper
• Toxoplasmosis Gondii Infection and Diabetes Mellitus Type 2 Treated by Using Autologous Peripheral Blood Stem Cells a Unique Case Report of a Caucasian 83 Year Old Lady

  2015influential citation
• Akute myeloische Leukämie

  2015cites this paper
• Higher percentage of CD34 + CD38− cells detected by multiparameter flow cytometry from leukapheresis products predicts unsustained complete remission in acute myeloid leukemia

  2015cites this paper
• Outcome of myeloablative allogeneic peripheral blood hematopoietic stem cell transplantation for refractory/relapsed AML patients in NR status.

  2015cites this paper
• The effects of idarubicin versus other anthracyclines for induction therapy of patients with newly diagnosed leukaemia.

  2015cites this paper
• Study of the underlying mechanism of the hypercoagulable state in acute leukaemia and impact of specific treatments on the thrombotic risk

  2015cites this paper
• T-cell-replete haploidentical transplantation versus autologous stem cell transplantation in adult acute leukemia: a matched pair analysis

  2015influential citation
• Indications for hematopoietic transplantation for aml

  2015cites this paper
• High numbers of mobilized CD34+ cells collected in AML in first remission are associated with high relapse risk irrespective of treatment with autologous peripheral blood SCT or autologous BMT

  2015cites this paper
• Autologous Peripheral Blood Stem Cells and γ / δ T Cells May Improve Immunity in Treating Secondary Bacteremic Infection in HIV Infected Patient

  2015cites this paper