Differential interactions of Rel‐NF‐kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF‐kappa B activity.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  EMBO Journal

• Publication date

  1994-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/j.1460-2075.1994.tb06782.xPMID 7925301PMCID PMC395393
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• The I kappa B proteins: members of a multifunctional family.

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• A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation

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• Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation.

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• A lymphoid cell-specific nuclear factor containing c-Rel-like proteins preferentially interacts with interleukin-6 kappa B-related motifs whose activities are repressed in lymphoid cells

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• The regulation of transcription by phosphorylation.

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• I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.

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• The inducible transcription activator NF-κB: regulation by distinct protein subunits

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• INTRODUCTION

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