Genetic control of sex determination in Drosophila.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Advances in Genetics

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0065-2660(08)60026-7PMID 2112300
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Genetic control of wing disc development in Drosophila.

  2008cited by this paper
• Sex determination in the germ line of Drosophila depends on genetic signals and inductive somatic factors.

  1989cited by this paper
• The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins.

  1989cited by this paper
• Sex-specific alternative splicing of RNA from the transformer gene results from sequence-dependent splice site blockage.

  1989cited by this paper
• Cell-autonomous and inductive signals can determine the sex of the germ line of drosophila by regulating the gene Sxl.

  1989cited by this paper
• Distal-less encodes a homoeodomain protein required for limb development in Drosophila

  1989cited by this paper
• RNA-binding proteins as developmental regulators.

  1989cited by this paper
• Measurement of anomalously high hydration of (dA) n · (dT) n double helices in dilute solution

  1989cited by this paper
• Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides.

  1989cited by this paper
• The gradient morphogen bicoid is a concentration-dependent transcriptional activator.

  1989cited by this paper
• The scute (T4) gene acts as a numerator element of the X:a signal that determines the state of activity of sex‐lethal in Drosophila.

  1989cited by this paper
• Transposition of the Responder element (Rsp) of the Segregation distorter system (SD) to the X chromosome in Drosophila melanogaster.

  1989cited by this paper
• Identification of yolk protein factor 1, a sequence-specific DNA-binding protein from Drosophila melanogaster.

  1989cited by this paper
• The Drosophila female-specific sex-determination gene, Sex-lethal, has stage-, tissue-, and sex-specific RNAs suggesting multiple modes of regulation.

  1989cited by this paper
• A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.

  1989cited by this paper
• DNA regions that regulate the ovarian transcriptional specificity of Drosophila yolk protein genes.

  1989cited by this paper
• Molecular genetics of transformer, a genetic switch controlling sexual differentiation in Drosophila.

  1989cited by this paper
• Sex in flies: the splice of life

  1989cited by this paper
• Proximal—distal pattern formation in Drosophila: cell autonomous requirement for Distal‐less gene activity in limb development

  1989cited by this paper
• Evolutionary Mechanisms in Sex Determination

  1988cited by this paper
• Ectopic expression of the female transformer gene product leads to female differentiation of chromosomally male Drosophila.

  1988cited by this paper
• Structure and expression of a Drosophila male accessory gland gene whose product resembles a peptide pheromone precursor.

  1988cited by this paper
• Sex-specific gene expression in somatic tissues of Drosophila melanogaster.

  1988cited by this paper
• Genetic evidence that the sans fille locus is involved in Drosophila sex determination.

  1988cited by this paper
• Temporal regulation in development: negative and positive cis regulators dictate the precise timing of expression of a Drosophila chorion gene.

  1988cited by this paper
• Molecular characterization of daughterless, a Drosophila sex determination gene with multiple roles in development.

  1988cited by this paper
• The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster.

  1988cited by this paper
• Sex determination in Drosophila: the X‐chromosomal gene liz is required for Sxl activity.

  1988cited by this paper
• Determination of male-specific gene expression in Drosophila accessory glands.

  1988cited by this paper
• The maternal sex determination gene daughterless has zygotic activity necessary for the formation of peripheral neurons in Drosophila.

  1988cited by this paper
• Microinjected DNA from the X chromosome affects sex determination in Caenorhabditis elegans.

  1988cited by this paper
• Evidence that sisterless-a and sisterless-b are two of several discrete "numerator elements" of the X/A sex determination signal in Drosophila that switch Sxl between two alternative stable expression states.

  1988cited by this paper
• The sex-determining gene tra-2 of Drosophila encodes a putative RNA binding protein.

  1988cited by this paper
• daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex.

  1988cited by this paper
• A male accessory gland peptide that regulates reproductive behavior of female D. melanogaster.

  1988cited by this paper
• Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins.

  1988cited by this paper
• A molecular analysis of doublesex, a bifunctional gene that controls both male and female sexual differentiation in Drosophila melanogaster.

  1988cited by this paper
• A short 5'-flanking DNA region is sufficient for developmentally correct expression of moth chorion genes in Drosophila.

  1987cited by this paper
• Genetic and developmental analysis of the sex-determining gene ‘double sex’ ( dsx ) of Drosophila melanogaster

  1987cited by this paper
• Molecular genetic aspects of sex determination in Drosophila

  1987cited by this paper
• Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene.

  1987cited by this paper
• The molecular basis for metameric pattern in the Drosophila embryo.

  1987cited by this paper
• Sequences expressed sex-specifically in Drosophila melanogaster adults.

  1987cited by this paper
• (dC‐dA)n.(dG‐dT)n sequences have evolutionarily conserved chromosomal locations in Drosophila with implications for roles in chromosome structure and function.

  1987cited by this paper
• Sexual behavior: its genetic control during development and adulthood in Drosophila melanogaster.

  1987cited by this paper
• Gene dosage compensation in Drosophila melanogaster.

  1987cited by this paper
• Spatially regulated expression of chorion genes during Drosophila oogenesis

  1987cited by this paper
• Dosage Compensation in Drosophila: Evidence That daughterless and Sex-lethal Control X Chromosome Activity at the Blastoderm Stage of Embryogenesis.

  1987cited by this paper
• Cloning and characterization of a dispersed, multicopy, X chromosome sequence in Drosophila melanogaster.

  1987cited by this paper
• The achaete-scute gene complex of D. melanogaster: conserved domains in a subset of genes required for neurogenesis and their homology to myc.

  1987cited by this paper
• The nucleotide sequence of the gene coding for Drosophila melanogaster yolk protein 3.

  1987cited by this paper
• The Drosophila sex determination gene daughterless has different functions in the germ line versus the soma.

  1987cited by this paper
• Precision and orderliness in splicing

  1987cited by this paper
• Functional changes associated with structural alterations induced by mobilization of a P element inserted in the Sex-lethal gene of Drosophila.

  1987cited by this paper
• A molecular analysis of transformer, a gene in Drosophila melanogaster that controls female sexual differentiation.

  1987cited by this paper
• The sex‐determining gene tra of Drosophila: molecular cloning and transformation studies.

  1986cited by this paper
• A tissue-specific transcription enhancer from the Drosophila yolk protein 1 gene.

  1986cited by this paper
• Expression of the Genes Coding for Vitellogenin (Yolk Protein)

  1986cited by this paper
• The regulation of male‐specific transcripts by sex determining genes in Drosophila melanogaster

  1986cited by this paper
• Analysis of the dosage compensation of a specific transcript in Drosophila melanogaster.

  1986cited by this paper
• A female-specific lethal lesion in an X-linked positive regulator of the Drosophila sex determination gene, Sex-lethal.

  1986cited by this paper
• The Origin and evolution of sex

  1985cited by this paper
• A single principle for sex determination in insects.

  1985cited by this paper
• Sex-specific regulation of yolk protein gene expression in Drosophila.

  1985cited by this paper
• Regulatory elements controlling chorion gene expression are conserved between flies and moths

  1985cited by this paper
• Independent control elements that determine yolk protein gene expression in alternative Drosophila tissues.

  1985cited by this paper
• A small region on the X chromosome of Drosophila regulates a key gene that controls sex determination and dosage compensation.

  1985cited by this paper
• The hierarchical relation between X‐chromosomes and autosomal sex determining genes in Drosophila

  1985cited by this paper
• Molecular genetics of the achaete-scute gene complex of D. melanogaster.

  1985cited by this paper
• Normal female germ cell differentiation requires the female X chromosome to autosome ratio and expression of sex-lethal in Drosophila melanogaster.

  1985cited by this paper
• Control of sexual differentiation in Drosophila melanogaster.

  1985cited by this paper
• The Sex-lethal gene of Drosophila: DNA alterations associated with sex-specific lethal mutations.

  1985cited by this paper
• Sex-lethal, a link between sex determination and sexual differentiation in Drosophila melanogaster.

  1985cited by this paper
• Sex determination: a hypothesis based on noncoding DNA.

  1985cited by this paper
• Sex determination in Drosophila

  1985cited by this paper
• The genetic specification of pattern in a Drosophila muscle.

  1984cited by this paper
• Autoregulatory functioning of a Drosophila gene product that establish es and maintains the sexually determined state.

  1984cited by this paper
• Sex-specific control of growth and differentiation in the Drosophila genital disc, studied using a temperature-sensitive transformer-2 mutation.

  1983cited by this paper
• Sex determination and dosage compensation in Drosophila melanogaster.

  1983cited by this paper
• The interaction between daughterless and sex-lethal in triploids: a lethal sex-transforming maternal effect linking sex determination and dosage compensation in Drosophila melanogaster.

  1983cited by this paper
• Sex determination and dosage compensation in Drosophila melanogaster: production of male clones in XX females

  1983cited by this paper
• Sequence and structure conservation in yolk proteins and their genes.

  1983cited by this paper
• 20-hydroxyecdysone stimulates tissue-specific yolk-protein gene transcription in both male and female Drosophila.

  1983cited by this paper
• Analysis of haploid mosaics in Drosophila.

  1983cited by this paper
• The dual functions of a sex determination gene in Drosophila melanogaster.

  1983cited by this paper
• The role of the transformer genes in the development of genitalia and analia of Drosophila melanogaster.

  1982cited by this paper
• Genetic and developmental evidence for a repressed genital primordium in Drosophila melanogaster.

  1982cited by this paper
• Sex determination in Drosophila melanogaster: analysis of transformer-2, a sex-transforming locus.

  1982cited by this paper
• Hormonal and Genetic Regulation of Vitellogenesis in Drosophila

  1982cited by this paper
• Autosomal mutations that interfere with sex determination in somatic cells of Drosophila have no direct effect on the germline.

  1982cited by this paper
• Sex-determinants and their distribution in various populations of Musca domestica L. of Western Europe.

  1982cited by this paper
• The follicle cells are a major site of vitellogenin synthesis in Drosophila melanogaster.

  1982cited by this paper
• An X chromosome locus in Drosophila melanogaster that enhances survival of the triplo‐lethal genotype, Dp‐(Tpl)

  1981cited by this paper
• The sequence of the Drosophila melanogaster gene for yolk protein 1.

  1981cited by this paper
• Sexual phenotype and vitellogenin synthesis in Drosophila melanogaster.

  1980cited by this paper
• Yolk protein synthesis in ovariectomized and genetically agametic [X87]Drosophila melanogaster.

  1980cited by this paper
• The isolation and characterization of Drosophila yolk protein genes.

  1980cited by this paper
• Control of X chromosome transcription by the maleless gene in Drosophila

  1980cited by this paper
• Sex and the single cell. I. On the action of major loci affecting sex determination in Drosophila melanogaster.

  1980cited by this paper
• The Regulation of yolk polypeptide synthesis in Drosophila ovaries and fat body by 20-hydroxyecdysone and a juvenile hormone analog.

  1980cited by this paper

• Title Transcription activator-like effector nuclease ( TALEN )-mediated female-specific sterility in the silkworm , Bombyx mori Permalink

  2014cites this paper
• Analysis of interaction between Bmhrp28 and BmPSI in sex-specific splicing of Bombyx mori Bmdsx gene.

  2014cites this paper
• Transcription activator‐like effector nuclease (TALEN)‐mediated female‐specific sterility in the silkworm, Bombyx mori

  2014cites this paper
• Neuroblast pattern and identity in the Drosophila tail region and role of doublesex in the survival of sex-specific precursors

  2013cites this paper
• Novel female-specific splice form of dsx in the silkworm, Bombyx mori

  2010cites this paper
• Two female-specific DSX proteins are encoded by the sex-specific transcripts of dsx, and are required for female sexual differentiation in two wild silkmoth species, Antheraea assama and Antheraea mylitta (Lepidoptera, Saturniidae).

  2010cites this paper
• Maniatis elements of the Drosophila doublesex splicing enhancer . Assembly of specific SR protein complexes on distinct regulatory

  2007cites this paper
• The Sex-Determination Genes fruitless and doublesex Specify a Neural Substrate Required for Courtship Song

  2007cites this paper
• Sex-specific death in the Asian corn borer moth (Ostrinia furnacalis) infected with Wolbachia occurs across larval development.

  2007cites this paper
• Role of the male BmDSX protein in the sexual differentiation of Bombyx mori

  2005cites this paper
• 1.1 – Sex Determination and the Development of the Genital Disc

  2005cites this paper
• Genetic studies on pheromone production in Drosophila

  2003cites this paper
• Analysis of the biological functions of a doublesex homologue in Bombyx mori

  2003cites this paper
• Maternal-offspring conflict leads to the evolution of dominant zygotic sex determination

  2002cites this paper
• The mechanism of sex-specific splicing at the doublesex gene is different between Drosophila melanogaster and Bombyx mori.

  2001cites this paper
• The development of the Drosophila genital disc

  2001cites this paper
• Sex determination genes control the development of the Drosophila genital disc, modulating the response to Hedgehog, Wingless and Decapentaplegic signals.

  2001cites this paper
• Maternal-zygotic gene conflict over sex determination: effects of inbreeding.

  2000cites this paper
• Requirement offlex (femalelethal onX) in the development of the female germ line ofDrosophila melanogaster

  1999cites this paper
• Tom Maniatis Enhancer Sequences Identification of Novel SR Protein-Specific Pre-mRNA Splicing Enhancers : Selection and Characterization of

  1999cites this paper
• Selection and Characterization of Pre-mRNA Splicing Enhancers: Identification of Novel SR Protein-Specific Enhancer Sequences

  1999cites this paper
• Elimination of X Chromosomes and the Problem of Sex Determination in Sciara ocellaris

  1998cites this paper
• Mechanisms and Evolutionary Origins of Gene Dosage Compensation

  1998cites this paper
• A search for additional X-linked genes affecting sex determination inDrosophila melanogaster

  1998cites this paper
• The Bactrocera tryoni homologue of the Drosophila melanogaster sex‐determination gene doublesex

  1998cites this paper
• SEX DETERMINATION, SEX RATIOS AND GENETIC CONFLICT

  1998influential citation
• virilizer regulates Sex-lethal in the germline of Drosophila melanogaster.

  1998cites this paper
• Conservation and divergence in the control of yolk protein genes in dipteran insects

  1997cites this paper
• The genital disc of Drosophila melanogaster

  1997cites this paper
• Reproductive isolation and morphogenetic evolution in Drosophila analyzed by breakage of ethological barriers.

  1997cites this paper
• dissatisfaction, a gene involved in sex-specific behavior and neural development of Drosophila melanogaster.

  1997cites this paper
• att, a target for regulation by tra2 in the testes of Drosophila melanogaster, encodes alternative RNAs and alternative proteins

  1996cites this paper
• Evolution of sex determination in caenorhabditis: unusually high divergence of tra-1 and its functional consequences.

  1996cites this paper
• The Drosophila Sex-Peptide: A Peptide Pheromone Involved in Reproduction

  1996cites this paper
• Identification of ovarian enhancer-binding factors which bind to ovarian enhancer 1 of theDrosophila genesyp1 andyp2

  1996cites this paper
• Interallelic complementation at the suppressor of forked locus of Drosophila reveals complementation between suppressor of forked proteins mutated in different regions.

  1996cites this paper
• The gene fl(2)d is needed for the sex-specific splicing of transformer pre-mRNA but not for double-sex pre-mRNA in Drosophila melanogaster

  1996cites this paper
• Regulation of the gene Sex-lethal: a comparative analysis of Drosophila melanogaster and Drosophila subobscura.

  1996cites this paper
• Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer.

  1996cites this paper
• A sex-specific number of germ cells in embryonic gonads of Drosophila.

  1995cites this paper
• Multiple response elements in the Sex-lethal early promoter ensure its female-specific expression pattern

  1995cites this paper
• The regulation of yolk protein 3 gene expression in Drosophila melanogaster

  1995cites this paper
• Two independent cis-acting elements regulate the sex- and tissue-specific expression of yp3 in Drosophila melanogaster.

  1995cites this paper
• scute (sis-b) function in Drosophila sex determination

  1995cites this paper
• Posttranscriptional Regulation and RNA Binding Proteins in Development.

  1995cites this paper
• Sex determination in Hymenoptera: a need for genetic and molecular studies.

  1995cites this paper
• The dual role of hermaphrodite in the Drosophila sex determination regulatory hierarchy.

  1995cites this paper
• The gene virilizer is required for female-specific splicing controlled by Sxl, the master gene for sexual development in Drosophila.

  1995cites this paper
• sex determination regulatory hierarchy

  1995cites this paper
• Synergistic interactions between two distinct elements of a regulated splicing enhancer.

  1995cites this paper
• P Schedl expression pattern . early promoter ensure its female-specific Multiple response elements in the Sex-lethal

  1995cites this paper
• The regulation of the yolk protein genes, a family of sex differentiation genes in Drosophila melanogaster

  1994cites this paper
• ARY dual role of hermaphrodite in the Droso latory hierarchy

  1994cites this paper
• A genetic analysis of hermaphrodite, a pleiotropic sex determination gene in Drosophila melanogaster.

  1994cites this paper
• Characterization of RNA binding specificity of the Drosophila sex-lethal protein by in vitro ligand selection.

  1994cites this paper
• Sex determination of the Drosophila germ line: tra and dsx control somatic inductive signals.

  1994cites this paper
• Synergistic interaction between particular X-chromosome deletions andSex-lethal causes female lethality inDrosophila melanogaster

  1994cites this paper
• Sex determination and dosage compensation: lessons from flies and worms.

  1994cites this paper
• Behavioral and neurobiological implications of sex-determining factors in Drosophila.

  1994cites this paper
• The concentration of B52, an essential splicing factor and regulator of splice site choice in vitro, is critical for Drosophila development

  1994cites this paper
• Tumor suppressor and overgrowth suppressor genes of Drosophila melanogaster: developmental aspects.

  1994cites this paper
• Sex determination and differentiation.

  1994cites this paper
• Molecular population genetics of sex determination genes: the transformer gene of Drosophila melanogaster.

  1994cites this paper
• The Role of Specific Protein-RNA and protln- Intm in Positive and (zontrol of A Splicing by r2

  1994cites this paper
• The mating of a fly.

  1994cites this paper
• The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2.

  1994cites this paper
• Genetic and biochemical analysis of alternative RNA splicing.

  1994cites this paper
• Sxl in the germline of Drosophila: a target for somatic late induction.

  1994cites this paper
• Yolk proteins from insect eggs: Structure, biosynthesis and programmed degradation during embryogenesis

  1994cites this paper
• RNA binding by Sxl proteins in vitro and in vivo

  1994cites this paper
• Homology between the mammalian liver and the Drosophila fat body.

  1993cites this paper
• Regulation of the sex-specific binding of the maleless dosage compensation protein to the male X chromosome in Drosophila.

  1993cites this paper
• Cis-regulatory sequences leading to female-specific expression of yolk protein genes 1 and 2 in the fat body of Drosophila melanogaster

  1993cites this paper
• The role of the ovarian tumor locus in Drosophila melanogaster germ line sex determination.

  1993cites this paper
• Functional gene cassettes in development.

  1993cites this paper
• Expression of the Sex-lethal gene is controlled at multiple levels during Drosophila oogenesis.

  1993cites this paper
• The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain.

  1993cites this paper
• The evolution of unusual chromosomal systems in coccoids: extraordinary sex ratios revisited

  1993cites this paper
• Sex determination in Drosophila: sis-b, a major numerator element of the X:A ratio in the soma, does not contribute to the X:A ratio in the germ line.

  1993cites this paper
• Sex-specific transcriptional regulation by the male and female doublesex proteins of Drosophila.

  1993cites this paper
• achaete-scute feminizing activities and Drosophila sex determination.

  1993cites this paper
• A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA.

  1993cites this paper
• deadpan, an essential pan-neural gene encoding an HLH protein, acts as a denominator in Drosophila sex determination.

  1992cites this paper
• Sex determination and differentiation in invertebrates: Drosophila and Caenorhabditis elegans.

  1992cites this paper
• The primary sex determination signal of Drosophila acts at the level of transcription.

  1992cites this paper
• The genetic analysis of snf: a Drosophila sex determination gene required for activation of Sex-lethal in both the germline and the soma.

  1992cites this paper
• How do germ cells choose their sex? Drosophila as a paradigm

  1992cites this paper
• Common denominators for sex.

  1992cites this paper
• Classical sex education.

  1992cites this paper
• Commitment of abdominal neuroblasts in Drosophila to a male or female fate is dependent on genes of the sex-determining hierarchy.

  1992cites this paper
• The segmentation gene runt is needed to activate Sex-lethal, a gene that controls sex determination and dosage compensation in Drosophila.

  1992cites this paper
• Positive control of pre-mRNA splicing in vitro.

  1992cites this paper
• Differentiation of a male-specific muscle in Drosophila melanogaster does not require the sex-determining genes doublesex or intersex.

  1992cites this paper
• Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product.

  1992cites this paper
• Interspecific comparison of the transformer gene of Drosophila reveals an unusually high degree of evolutionary divergence.

  1992cites this paper
• The temperature-sensitive mutation virts(virilizer) identifies a new gene involved in sex determination of Drosophila

  1991cites this paper
• The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes.

  1991cites this paper
• The sisterless-b function of the Drosophila gene scute is restricted to the stage when the X:A ratio determines the activity of Sex-lethal.

  1991cites this paper
• The complex set of late transcripts from the Drosophila sex determination gene sex-lethal encodes multiple related polypeptides

  1991cites this paper
• Developmental distribution of female-specific Sex-lethal proteins in Drosophila melanogaster.

  1991cites this paper