Pituitary adenylate cyclase-activating polypeptide, interleukin-6 and glucocorticoids regulate the release of vascular endothelial growth factor in pituitary folliculostellate cells.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Endocrinology

• Publication date

  1999-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1677/JOE.0.1600483PMID 10076194
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interleukin-6 is an autocrine growth factor for folliculostellate-like TtT/GF mouse pituitary tumor cells.

  2009cited by this paper
• Interactions between normal and tumoral tissues at the boundary of human anterior pituitary adenomas

  2004cited by this paper
• The biology of vascular endothelial growth factor.

  1997influential reference
• Induction of vascular endothelial growth factor by platelet-activating factor and platelet-derived growth factor is downregulated by corticosteroids.

  1997cited by this paper
• Pattern and localisation of expression of vascular endothelial growth factor and its receptor flt-1 in the ovine pituitary gland: expression is independent of hypothalamic control.

  1997influential reference
• Over expression of vascular endothelial growth factor and its receptor during the development of estrogen-induced rat pituitary tumors may mediate estrogen-initiated tumor angiogenesis.

  1997cited by this paper
• Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis

  1996cited by this paper
• Vascular endothelial growth factor and its receptors.

  1996cited by this paper
• Interleukin 6 Induces the Expression of Vascular Endothelial Growth Factor (*)

  1996cited by this paper
• Embryonic angiogenesis: A review

  1996cited by this paper
• Progesterone induces vascular endothelial growth factor on retinal pigment epithelial cells in culture.

  1996cited by this paper
• Mechanism of dexamethasone suppression of brain tumor-associated vascular permeability in rats. Involvement of the glucocorticoid receptor and vascular permeability factor.

  1996cited by this paper
• Pituitary adenylate cyclase-activating polypeptide (PACAP) and PACAP/vasoactive intestinal polypeptide receptors: actions on the anterior pituitary gland.

  1996influential reference
• Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosis.

  1996cited by this paper
• Thyroid-stimulating hormone promotes the secretion of vascular endothelial growth factor in thyroid cancer cell lines.

  1996cited by this paper
• Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

  1995cited by this paper
• Involvement of interleukin-1 and interleukin-1 receptor antagonist in rat pituitary cell growth regulation.

  1995cited by this paper
• Pituitary folliculo-stellate-like cells stimulate somatotropic pituitary tumor growth in nude mice

  1995cited by this paper
• Endothelial receptor tyrosine kinases involved in angiogenesis

  1995cited by this paper
• S–100 Antigen‐Positive Folliculostellate Cells are not the Source of IL‐6 Gene Expression in Human Pituitary Adenomas

  1995cited by this paper
• Production of bioactive and immunoreactive interleukin-6 (IL-6) and expression of IL-6 messenger ribonucleic acid by human pituitary adenomas.

  1994cited by this paper
• Interleukin involvement in anterior pituitary cell growth regulation: effects of IL-2 and IL-6.

  1993cited by this paper
• Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis.

  1993cited by this paper
• Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.

  1993cited by this paper
• Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth.

  1993cited by this paper
• High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis.

  1993cited by this paper
• Pituitary folliculo-stellate-like cell line (TtT/GF) responds to novel hypophysiotropic peptide (pituitary adenylate cyclase-activating peptide), showing increased adenosine 3',5'-monophosphate and interleukin-6 secretion and cell proliferation.

  1993influential reference
• Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

  1993cited by this paper
• Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: identification as leukemia inhibitory factor.

  1992cited by this paper
• Establishment of a folliculo-stellate-like cell line from a murine thyrotropic pituitary tumor.

  1992cited by this paper
• S-100 protein immunopositivity in human nontumorous hypophyses and pituitary adenomas

  1992cited by this paper
• Release of interleukin-6 from anterior pituitary cell aggregates: developmental pattern and modulation by glucocorticoids and forskolin.

  1991cited by this paper
• New perspectives in the function of pituitary folliculo-stellate cells.

  1990cited by this paper
• Vascular endothelial growth factor is a secreted angiogenic mitogen.

  1989cited by this paper
• Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells.

  1989cited by this paper
• Production of interleukin-6 by folliculo-stellate cells of the anterior pituitary gland in a histiotypic cell aggregate culture system.

  1989cited by this paper
• Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells.

  1989cited by this paper
• Pituitary follicular cells produce basic fibroblast growth factor.

  1987cited by this paper
• ELECTRON MICROSCOPIC STUDIES OF THE ANTERIOR PITUITARY GLAND

  1953cited by this paper

• Hypophysial angiogenesis decodes annual time and underlies physiological adaptation to seasonal changes in the environment

  2022cites this paper
• THE TUMOUR MICROENVIRONMENT OF PITUITARY NEUROENDOCRINE TUMOURS.

  2020cites this paper
• A report of three cases which required tibialis anterior tendon resection to recover delayed wound healing after total ankle arthroplasty in patients with rheumatoid arthritis

  2020cites this paper
• Cytokines in Endocrine Dysfunction of Plasma Cell Disorders

  2017cites this paper
• A PACAP szerepének vizsgálata retina pigmenthámsejtekben

  2017cites this paper
• Programmed cell senescence: role of IL-6 in the pituitary.

  2017cites this paper
• Sex differences in the effect of acute peripheral IL‐1&bgr; administration on the brain and serum BDNF and VEGF expression in rats

  2017cites this paper
• PACAP in the Reproductive System

  2016cites this paper
• Molecular Mechanisms Underlying Pituitary Pathogenesis

  2016cites this paper
• The Neuropeptide PACAP, a Potent Disease Modifier Candidate for Brain Stroke Treatment

  2016cites this paper
• Age‐Related Decline of Autocrine Pituitary Adenylate Cyclase‐Activating Polypeptide Impairs Angiogenic Capacity of Rat Cerebromicrovascular Endothelial Cells

  2015cites this paper
• Delayed Pituitary Adenylate Cyclase–Activating Polypeptide Delivery After Brain Stroke Improves Functional Recovery by Inducing M2 Microglia/Macrophage Polarization

  2015cites this paper
• Vascular Endothelial Growth Factor Secretion from Pituitary Folliculostellate Cells: Role of KATP Channels

  2014cites this paper
• Multifaces of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP):From Neuroprotection and Energy Homeostasis to Respiratory andCardiovascular Systems

  2014cites this paper
• Effect of ultra-short wave on hormone-induced ischemic necrosis of femoral head in early stage

  2014cites this paper
• Caractérisation morphologique, biochimique et physiologique des protéines de jonction lacunaire, les connexines 46 et 50, dans les cellules folliculo-stellaires TtT/GF de l’hypophyse antérieure

  2014cites this paper
• Excess Maternal Glucocorticoids in Response to In Utero Undernutrition Inhibit Offspring Angiogenesis

  2014cites this paper
• Hypoxia preconditioned bone marrow mesenchymal stem cells promote liver regeneration in a rat massive hepatectomy model

  2013influential citation
• Hypoxia preconditioned bone marrow mesenchymal stem cells promoted liver regeneration in a rat massive hepatectomy model

  2013influential citation
• Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas.

  2012cites this paper
• Vorkommen und Funktion des toll-like Rezeptor 2 in follikulostellaren Hypophysenzellen

  2012cites this paper
• Cellular and molecular specificity of pituitary gland physiology.

  2012cites this paper
• Effect of PACAP on MAP kinases, Akt and cytokine expressions in rat retinal hypoperfusion.

  2012cites this paper
• Hypoxia-induced VEGF production 'RSUMEs' in pituitary adenomas.

  2012cites this paper
• Folliculo-stellate Cells: Paracrine Communicators in the Anterior Pituitary

  2011cites this paper
• Intrapituitary cytokines in Cushing’s disease: do they play a role?

  2011cites this paper
• The novel sumoylation enhancer RSUME is implicated in pituitary tumor pathogenesis

  2010cites this paper
• Dexamethasone induces neurodegeneration but also up-regulates vascular endothelial growth factor A in neonatal rat brains.

  2009cites this paper
• Dehydroepiandrosterone Pretreatment Alters the Ischaemia/Reperfusion-Induced VEGF, IL-1 and IL-6 Gene Expression in Acute Renal Failure

  2009cites this paper
• Regulation of Pituitary Function by Cytokines

  2009cites this paper
• Intrapituitary Expression and Regulation of the gp130 Cytokine Interleukin‐6 and Its Implication in Pituitary Physiology and Pathophysiology

  2009cites this paper
• Vascular endothelial growth factor during hypoglycemia in patients with type 1 diabetes mellitus: relation to cognitive function and renin-angiotensin system activity.

  2009cites this paper
• Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery

  2009cites this paper
• Differential Gene Expression in Models of Pituitary Prolactin-Producing Tumoral Cells

  2009cites this paper
• Glucocorticoid and Growth Factor Synergism Requirement for Notch4 Chromatin Domain Activation

  2007cites this paper
• Protective effects of pituitary adenylate cyclase activating polypeptide in endothelial cells against oxidative stress-induced apoptosis.

  2007cites this paper
• Paracrinicity: The Story of 30 Years of Cellular Pituitary Crosstalk

  2007cites this paper
• UvA-DARE ( Digital Academic Repository ) The TSH receptor in the pituitary and its clinical relevance

  2007cites this paper
• Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) in the cochlea: evidence for specific transcript expression of PAC1-R splice variants in rat microdissected cochlear subfractions.

  2006cites this paper
• Modulation of GJA1 Turnover and Intercellular Communication by Proinflammatory Cytokines in the Anterior Pituitary Folliculostellate Cell Line TtT/GF1

  2006cites this paper
• Pituitary today : molecular, physiological and clinical aspects

  2006cites this paper
• Molekulare und pathologische Aspekte der para- und autokrinen Hypophysenregulation durch Zytokine und Wachstumsfaktoren

  2006cites this paper
• Vascularization of rat pituitary autografts

  2006cites this paper
• Integration of stimulatory and inhibitory signals in pituitary tumor cells through the PI3K pathway

  2006cites this paper
• Dopaminergic D2 receptor knockout mouse: an animal model of prolactinoma.

  2006cites this paper
• Localization of vascular endothelial growth factor (VEGF) receptors in normal and adenomatous pituitaries: detection of a non-endothelial function of VEGF in pituitary tumours.

  2006influential citation
• Genesis of prolactinomas: studies using estrogen-treated animals.

  2006cites this paper
• Hyperosmotic stimulus induces reversible angiogenesis within the hypothalamic magnocellular nuclei of the adult rat: a potential role for neuronal vascular endothelial growth factor

  2005cites this paper
• Expression of hypoxia-inducible factor 1α and vascular endothelial growth factor in pituitary adenomas

  2005cites this paper
• Correlation of VEGF production with IL1 alpha and IL6 secretion by human pituitary adenoma cells.

  2005cites this paper
• Antecedent hypoglycaemia attenuates vascular endothelial growth factor response to subsequent hypoglycaemia in healthy men

  2005cites this paper
• Expression of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in human placenta.

  2005cites this paper
• Hormones of the pituitary

  2005cites this paper
• Correlation of VEGF production with IL1α and IL6 secretion by human pituitary adenoma cells

  2005cites this paper
• Expression of placenta growth factor mRNA in the rat placenta during mid-late pregnancy.

  2005cites this paper
• Chronic stress in the adult dentate gyrus reduces cell proliferation near the vasculature and VEGF and Flk‐1 protein expression

  2005influential citation
• Increased pituitary vascular endothelial growth factor-a in dopaminergic D2 receptor knockout female mice.

  2005cites this paper
• Pituitary cell lines and their endocrine applications.

  2004cites this paper
• Vasoactive intestinal peptide increases vascular endothelial growth factor expression and neuroendocrine differentiation in human prostate cancer LNCaP cells.

  2004cites this paper
• Expression of Adenohypophyseal-hormone Receptors in a Murine Folliculo-stellate Cell Line

  2004cites this paper
• Involvement of the gp130 cytokine transducer in MtT/S pituitary somatotroph tumour development in an autocrine-paracrine model.

  2004cites this paper
• Expression of novel neurotrophin-1/B-cell stimulating factor-3 (NNT-1/BSF-3) in murine pituitary folliculostellate TtT/GF cells: pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal peptide-induced stimulation of NNT-1/BSF-3 is mediated by protein kinase A, protein kinase C,

  2004cites this paper
• Steroid effects on osteogenesis through mesenchymal cell gene expression

  2004cites this paper
• Effects of Histamine and the H2 Receptor Antagonist Ranitidine on Ischemia-Induced Acute Renal Failure: Involvement of IL-6 and Vascular Endothelial Growth Factor

  2004cites this paper
• Folliculostellate cells determine the susceptibility of lactotropes to estradiol's mitogenic action.

  2004cites this paper
• Divergence of renal vascular endothelial growth factor mRNA expression and protein level in post‐ischaemic rat kidneys

  2004influential citation
• Pituitary adenylate cyclase activating polypeptide: a potential neuroprotective peptide.

  2004cites this paper
• Morphologic changes and molecular regulation of angiogenesis in pituitary adenomas.

  2004cites this paper
• The effects of PACAP and PACAP antagonist on the neurobehavioral development of newborn rats.

  2003cites this paper
• Function of PACAP in the Hypothalamo-Pituitary Complex

  2003cites this paper
• Novel insights into how purines regulate pituitary cell function.

  2003cites this paper
• Ultrastructural aspects of the follicular cells of the pars tuberalis in bats related to the seasonal cycle.

  2003cites this paper
• Angiogenesis in endocrine tumors.

  2003influential citation
• Angiogenesis in pituitary adenomas

  2003cites this paper
• Cellular localization of pituitary adenylate cyclase-activating polypeptide in the rat testis.

  2003cites this paper
• Rat anterior pituitary folliculostellate cells are targets of interleukin-1beta and a major source of intrapituitary follistatin.

  2003cites this paper
• Chapter 6 Glucocorticoids inhibit vascular endothelial growth factor expression in growth plate chondrocytes

  2003cites this paper
• Expression patterns of pituitary adenylate cyclase activating polypeptide and its type I receptor mRNAs in the rat placenta

  2003cites this paper
• Celecoxib, a selective cyclooxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in a streptozotocin-induced diabetic rat model.

  2003cites this paper
• Reduced expression of the cytokine transducer gp130 inhibits hormone secretion, cell growth, and tumor development of pituitary lactosomatotrophic GH3 cells.

  2003cites this paper
• PACAP Receptor Signaling

  2003cites this paper
• Function of PACAP in the Cardiovascular System

  2003cites this paper
• Microvascular density and vascular endothelial growth factor expression in normal pituitary tissue and pituitary adenomas

  2003cites this paper
• Adenosine‐induced IL‐6 expression in pituitary folliculostellate cells is mediated via A2b adenosine receptors coupled to PKC and p38 MAPK

  2003influential citation
• Physiological and pathological angiogenesis in the endocrine system

  2003influential citation
• Meninges and perivasculature as mediators of CNS plasticity

  2003cites this paper
• Transforming growth factor-beta stimulates vascular endothelial growth factor production by folliculostellate pituitary cells.

  2002cites this paper
• Vascular endothelial growth factor: a novel endocrine defensive response to hypoglycemia.

  2002cites this paper
• Glucocorticoids inhibit vascular endothelial growth factor expression in growth plate chondrocytes.

  2002cites this paper
• Evidence that PACAP and GnRH down-regulate follicle-stimulating hormone-beta mRNA levels by stimulating follistatin gene expression: effects on folliculostellate cells, gonadotrophs and LbetaT2 gonadotroph cells.

  2002cites this paper
• The TSH receptor in the pituitary and its clinical relevance

  2002cites this paper
• The neuroendocrine control of glucose allocation.

  2002cites this paper
• LES CELLULES FOLLICULOSTELLAIRES : UNITES FONCTIONNELLES D'UNE VOIE DE COMMUNICATION A LONGUE DISTANCE DANS L'HYPOPHYSE ANTERIEURE.

  2001influential citation
• Effects of the gp130 cytokines ciliary neurotropic factor (CNTF) and interleukin-11 on pituitary cells: CNTF receptors on human pituitary adenomas and stimulation of prolactin and GH secretion in normal rat anterior pituitary aggregate cultures.

  2001cites this paper
• Vascular Endothelial Growth Factor Production and Regulation in Rodent and Human Pituitary Tumor Cells in vitro

  2001cites this paper
• Hypothalamische und hypophysäre Erkrankungen.

  2001cites this paper
• Pituitary tumorigenesis and hPit-1 cells.

  2001cites this paper
• Calcitonin induces IL-6 production via both PKA and PKC pathways in the pituitary folliculo-stellate cell line.

  2001cites this paper
• Budesonide reduces vascular endothelial growth factor secretion and expression in airway (Calu-1) and alveolar (A549) epithelial cells.

  2001cites this paper
• Pituitary Tumor Angiogenesis

  2001cites this paper