Identification and characterization of a novel cytoskeleton-associated pp60src substrate

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Molecular and Cellular Biology

• Publication date

  1991-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/mcb.11.10.5113-5124.1991PMID 1922035PMCID PMC361526
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phosphorylation and activation of epidermal growth factor receptors in cells transformed by the src oncogene

  1991cited by this paper
• Cloning of PI3 kinase-associated p85 utilizing a novel method for expression/cloning of target proteins for receptor tyrosine kinases.

  1991cited by this paper
• cDNA cloning of a novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF beta-receptor.

  1991cited by this paper
• Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase.

  1991cited by this paper
• The SH2 and SH3 domains of pp60src direct stable association with tyrosine phosphorylated proteins p130 and p110.

  1991influential reference
• SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins.

  1991cited by this paper
• Deletions in the SH2 domain of p60v-src prevent association with the detergent-insoluble cellular matrix

  1991cited by this paper
• Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6.

  1991cited by this paper
• Oncogenes and signal transduction.

  1991cited by this paper
• Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein

  1991cited by this paper
• Tyrosine phosphorylation of a 120-kilodalton pp60src substrate upon epidermal growth factor and platelet-derived growth factor receptor stimulation and in polyomavirus middle-T-antigen-transformed cells

  1991cited by this paper
• Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

  1990influential reference
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  1990cited by this paper
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  1990cited by this paper
• Protein kinase recognition sequence motifs.

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• Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src

  1990cited by this paper
• Proteolytic activity of specialized surface protrusions formed at rosette contact sites of transformed cells.

  1989cited by this paper
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  1989cited by this paper
• Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage.

  1989cited by this paper
• Deletions within the amino-terminal half of the c-src gene product that alter the functional activity of the protein

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• The localization and sequence of the phosphorylation sites of Acanthamoeba myosins I. An improved method for locating the phosphorylated amino acid.

  1989cited by this paper
• Evidence that pp42, a major tyrosine kinase target protein, is a mitogen-activated serine/threonine protein kinase.

  1989cited by this paper
• Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stability

  1989cited by this paper
• Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

  1989influential reference
• cDNA cloning and sequencing of the protein‐tyrosine kinase substrate, ezrin, reveals homology to band 4.1.

  1989cited by this paper
• Genetics of src: structure and functional organization of a protein tyrosine kinase.

  1989cited by this paper
• Src homology 2 domain deletion mutants of p60v-src do not phosphorylate cellular proteins of 120-150 kDa.

  1989cited by this paper
• Linker insertion-deletion mutagenesis of the v-src gene: isolation of host- and temperature-dependent mutants

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  1989influential reference
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• Activation of pp60c-src tyrosine kinase specific activity in tumor-derived Syrian hamster embryo cells.

  1988cited by this paper
• Cloning of bovine GAP and its interaction with oncogenic ras p21

  1988cited by this paper
• A novel viral oncogene with structural similarity to phospholipase C

  1988cited by this paper
• Sequence similarity of phospholipase C with the non-catalytic region of src

  1988cited by this paper
• Improved tools for biological sequence comparison.

  1988cited by this paper
• Identification of multiple novel polypeptide substrates of the v-src, v-yes, v-fps, v-ros, and v-erb-B oncogenic tyrosine protein kinases utilizing antisera against phosphotyrosine.

  1988cited by this paper
• Phosphorylation of cellular proteins in Rous sarcoma virus-infected cells: analysis by use of anti-phosphotyrosine antibodies

  1988cited by this paper
• Activation of pp60c-src transforming potential by mutations altering the structure of an amino terminal domain containing residues 90-95.

  1988cited by this paper
• Focal adhesions: transmembrane junctions between the extracellular matrix and the cytoskeleton.

  1988cited by this paper
• Insulin-stimulated microtubule-associated protein kinase is phosphorylated on tyrosine and threonine in vivo.

  1988cited by this paper
• Nonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblasts.

  1988cited by this paper
• Non-catalytic domains of cytoplasmic protein-tyrosine kinases: regulatory elements in signal transduction.

  1988cited by this paper
• Molecular cloning of two types of GAP complementary DNA from human placenta.

  1988cited by this paper
• Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src.

  1987cited by this paper
• Cell transformation by the viral src oncogene.

  1987cited by this paper
• An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.

  1987cited by this paper
• Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation.

  1987cited by this paper
• cDNA cloning, sequencing and chromosome mapping of a non-erythroid spectrin, human alpha-fodrin.

  1987cited by this paper
• Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.

  1987cited by this paper
• Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain.

  1987cited by this paper
• Rous sarcoma virus-transformed fibroblasts and cells of monocytic origin display a peculiar dot-like organization of cytoskeletal proteins involved in microfilament-membrane interactions.

  1987cited by this paper
• The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activity

  1986cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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  1985cited by this paper
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  1985cited by this paper
• Stabilizing infrastructure of cell membranes.

  1985cited by this paper
• Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformation.

  1985cited by this paper
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  1984cited by this paper
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  1984cited by this paper
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  1984cited by this paper
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  1984cited by this paper
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  1980cited by this paper
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  1980cited by this paper
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  1979cited by this paper
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  1978cited by this paper
• Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein.

  1978cited by this paper
• DNA sequencing with chain-terminating inhibitors.

  1977cited by this paper
• Identification of a transformation-specific antigen induced by an avian sarcoma virus

  1977cited by this paper
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  1972cited by this paper

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