WoLF PSORT is an extension of the PSORT II program for protein subcellular location prediction. WoLF PSORT converts protein amino acid sequences into numerical localization features; based on sorting signals, amino acid composition and functional motifs such as DNA-binding motifs. After conversion, a simple k-nearest neighbor classifier is used for prediction. Using html, the evidence for each prediction is shown in two ways: (i) a list of proteins of known localization with the most similar localization features to the query, and (ii) tables with detailed information about individual localization features. For convenience, sequence alignments of the query to similar proteins and links to UniProt and Gene Ontology are provided. Taken together, this information allows a user to understand the evidence (or lack thereof) behind the predictions made for particular proteins. WoLF PSORT is available at wolfpsort.org
WoLF PSORT: protein localization predictor
Paul Horton,Keun-Joon Park,T. Obayashi,Naoya Fujita,Hajime Harada,C. J. Adams-Collier,Kenta Nakai
Published 2007 in Nucleic Acids Res.
ABSTRACT
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- Publication year
2007
- Venue
Nucleic Acids Res.
- Publication date
2007-05-21
- Fields of study
Biology, Medicine, Computer Science
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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