Proteome analysis of human aqueous humor.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Investigative Ophthalmology and Visual Science

• Publication date

  2010-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1167/iovs.10-5531PMID 20463327PMCID PMC3066620
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Myocilin Levels in Primary Open-angle Glaucoma and Pseudoexfoliation Glaucoma Human Aqueous Humor

  2010cited by this paper
• Pooling aqueous humor samples: bias in 2D-LC-MS/MS strategy?

  2010cited by this paper
• Aqueous humor dynamics in historical perspective.

  2010cited by this paper
• Proteomic analysis of human aqueous humor using multidimensional protein identification technology

  2009cited by this paper
• Proteomic analysis of aqueous humor from patients with myopia

  2008cited by this paper
• Proteomic analysis of human vitreous fluid by fluorescence-based difference gel electrophoresis (DIGE): a new strategy for identifying potential candidates in the pathogenesis of proliferative diabetic retinopathy

  2007cited by this paper
• Proteomics of the aqueous humor in healthy New Zealand rabbits

  2007cited by this paper
• Profiling of vitreous proteomes from proliferative diabetic retinopathy and nondiabetic patients

  2007cited by this paper
• TGFbeta2-induced changes in human trabecular meshwork: implications for intraocular pressure.

  2006cited by this paper
• Fluid Mechanics of the Human Eye: Aqueous Humour Flow in The Anterior Chamber

  2006cited by this paper
• Inhibition of angiogenesis by vitamin D-binding protein: Characterization of anti-endothelial activity of DBP-maf

  2006cited by this paper
• Proteomics analysis of prefractionated human lumbar cerebrospinal fluid

  2005cited by this paper
• Proteomics analysis of human cerebrospinal fluid.

  2005cited by this paper
• Proteomic analysis of aqueous humour from patients with acute corneal rejection.

  2005cited by this paper
• Matrix Metalloproteinases and Their Tissue Inhibitors in Aqueous Humor of Patients With Primary Open-Angle Glaucoma, Exfoliation Syndrome, and Exfoliation Glaucoma

  2005cited by this paper
• Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly‐available database

  2005cited by this paper
• Growth factors in the anterior segment: role in tissue maintenance, wound healing and ocular pathology.

  2004cited by this paper
• The Human Plasma Proteome

  2004cited by this paper
• The aqueous levels of TGF-beta2 in patients with glaucoma.

  2004cited by this paper
• In vitro and in vivo characterization of disulfide bond use in myocilin complex formation.

  2004cited by this paper
• A statistical model for identifying proteins by tandem mass spectrometry.

  2003cited by this paper
• Proteomics in uveal melanoma

  2003cited by this paper
• The mechanism of aqueous humour formation.

  2002cited by this paper
• Towards a high resolution separation of human cerebrospinal fluid.

  2002cited by this paper
• Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search.

  2002cited by this paper
• Characterization of myocilin-myocilin interactions.

  2001cited by this paper
• The presence and properties of myocilin in the aqueous humor.

  2001cited by this paper
• Recombinant TIGR/MYOC increases outflow resistance in the human anterior segment.

  2000cited by this paper
• Anti-angiogenic cues from vascular basement membrane collagen.

  2000cited by this paper
• TIGR/myocilin in human aqueous humor.

  2000cited by this paper
• Pigment epithelium-derived factor: a potent inhibitor of angiogenesis.

  1999cited by this paper
• Differential gene expression in the human ciliary epithelium.

  1999cited by this paper
• Uveoscleral Outflow in Dog's Eye: Role of Several Enzymes

  1998cited by this paper
• Soluble receptors in human disease

  1998cited by this paper
• Comparison of protein mixtures in aqueous humor by membrane preconcentration ‐ capillary electrophoresis ‐ mass spectrometry

  1998cited by this paper
• Gene expression of proteases and protease inhibitors in the human ciliary epithelium and ODM-2 cells.

  1997cited by this paper
• The Glenn A. Fry Award Lecture 1992: aqueous humor proteins: a key for unlocking glaucoma?

  1993cited by this paper
• A simple three-compartment model of anterior segment kinetics.

  1993cited by this paper
• The relationship between aqueous humor flow and anterior chamber protein concentration in rabbits.

  1993cited by this paper
• MMPs and proteinase inhibitors in the human aqueous humor.

  1993cited by this paper
• The source of protein in the aqueous humor of the normal monkey eye.

  1992cited by this paper
• Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins.

  1992cited by this paper
• The source of proteins in the aqueous humor of the normal rabbit.

  1990cited by this paper
• Glutathione S-transferase of bovine iris and ciliary body: characterization of isoenzymes.

  1989cited by this paper
• Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130.

  1989cited by this paper
• Protein composition of human aqueous humor: SDS-PAGE analysis of surgical and post-mortem samples.

  1989cited by this paper
• Alteration of a developmentally regulated, heat-stable polypeptide in the lens of the Philly mouse. Implications for cataract formation.

  1988cited by this paper
• Distribution of albumin in the normal monkey eye as revealed by Evans blue fluorescence microscopy.

  1980cited by this paper
• Two-dimensional gel electrophoresis of cerebrospinal fluid proteins.

  1980cited by this paper
• Structure and biosynthesis of basement membranes.

  1973cited by this paper
• Immunoglobulins in the human eye. Location, type, and amount.

  1973cited by this paper
• THE CHEMICAL COMPOSITION AND THE OSMOTIC PRESSURE OF THE AQUEOUS HUMOR AND PLASMA OF THE RABBIT

  1951cited by this paper

• Neutrophil Extracellular Trap Components Are Present in the Aqueous Humor of Glaucoma Patients

  2026cites this paper
• Blockade of mitochondrial components release by exosome pathway promotes the pathogenesis of Fuchs endothelial corneal dystrophy

  2025cites this paper
• Preparation of Human Trabecular Meshwork Cells for Metabolomic Studies.

  2025cites this paper
• Liquid Biopsy Combined with Multi-Omics Approaches in Diagnosis, Management, and Progression of Diabetic Retinopathy

  2025cites this paper
• Comparing Analyte Concentrations in Paired Tear Fluid and Blood Samples.

  2025cites this paper
• A Pilot Investigation of Transforming Growth Factor-β2 and Total Protein Concentrations in Aqueous Humor of Canine Glaucomatous Eyes With and Without Ahmed Glaucoma Valve Surgery.

  2025cites this paper
• Proteomics approach identifies aqueous humor biomarkers in retinal diseases

  2025cites this paper
• Azobenzene-Grafted Acrylate Coatings to Modulate Lens Epithelial Cells.

  2025cites this paper
• Proteasome and Ribosome Ubiquitination in Retinal Pigment Epithelial (RPE) Cells in Response to Oxidized Low-Density Lipoprotein (OxLDL)

  2025cites this paper
• Proteomics analysis of aqueous and vitreous humor in uveitis: a systematic literature review

  2025cites this paper
• 1000-plex antibody array proteomic screen uncovers PGRPS, Haptoglobin, Serpin A4 and Fibrinogen as potential stool biomarkers of pediatric inflammatory bowel disease.

  2025cites this paper
• A Model of the Mechanisms Underpinning Unconventional Aqueous Humor Outflow

  2025cites this paper
• Lanthanide Metal-Organic Framework Flowers for Proteome Profiling and Biomarker Identification in Ultratrace Biofluid Samples.

  2025cites this paper
• Interleukin‐24: A Multidimensional Therapeutic for Treatment of Human Diseases

  2025cites this paper
• Assessing Particle Release from Intraocular Lenses with a Combination of OptoFluidic Force Induction, μ-Raman and μ-FTIR

  2025cites this paper
• Proteomic Analysis of Aqueous Humor Identified Clinically Relevant Molecular Targets for Neovascular Complications in Diabetic Retinopathy

  2025cites this paper
• Clinical Course of Iris Retraction Syndrome Associated With Rhegmatogenous Retinal Detachment: A Report of Three Cases

  2025cites this paper
• Novel insight into MDA-7/IL-24: A potent therapeutic target for autoimmune and inflammatory diseases.

  2024cites this paper
• Implications of Ocular Confounding Factors for Aqueous Humor Proteomic and Metabolomic Analyses in Retinal Diseases

  2024cites this paper
• Comprehensive Proteomic Profiling of Aqueous Humor in Idiopathic Uveitis and Vogt–Koyanagi–Harada Syndrome

  2024cites this paper
• The Role of Biochemical Markers in Cataractogenesis. Literature Review

  2024cites this paper
• Elevated Serum Levels of Osteopontin in Patients with Psoriasis: Is It Associated with Ocular Comorbidities?

  2024cites this paper
• Aqueous humor proteomics analyzed by bioinformatics and machine learning in PDR cases versus controls

  2024cites this paper
• Comparative analysis of human tear fluid and aqueous humor proteomes.

  2024cites this paper
• Proteomic and Cytokine Profiling in Plasma from Patients with Normal-Tension Glaucoma and Ocular Hypertension

  2024cites this paper
• Liquid Biopsy Proteomics in Ophthalmology

  2024cites this paper
• Evaluation of Ocular and Systemic Oxidative Stress Markers in Patients with Diabetic Retinopathy

  2024cites this paper
• Proteomics identifies hypothermia induced adiponectin protects corneal endothelial cells via AMPK mediated autophagy in phacoemulsification

  2024cites this paper
• The Role of Complement Dysregulation in Glaucoma

  2024cites this paper
• Selective Upregulation of Interleukin 1 Receptor Antagonist and Interleukin-8 in Fuchs’ Endothelial Corneal Dystrophy with Accompanying Cataract

  2024cites this paper
• Ocular drug-metabolizing enzymes: focus on esterases

  2024cites this paper
• Advances in aqueous humor proteomics for biomarker discovery and disease mechanisms exploration: a spotlight on primary open angle glaucoma

  2024cites this paper
• Development and testing of a metabolic chamber for effluent collection during whole eye perfusions.

  2023cites this paper
• Complement System Proteins in the Human Aqueous Humor and Their Association with Primary Open-Angle Glaucoma

  2023cites this paper
• Superparamagnetic Composite Nanobeads Anchored with Molecular Glues for Ultrasensitive Label-free Proteomics.

  2023cites this paper
• Microfluidics in the eye: a review of glaucoma implants from an engineering perspective.

  2023cites this paper
• Vitreous Humor Proteomic Profile in Patients With Vitreoretinal Lymphoma

  2023cites this paper
• Biomarkers of Pediatric Cataracts: A Proteomics Analysis of Aqueous Fluid

  2023cites this paper
• New Biomarker Combination Related to Oxidative Stress and Inflammation in Primary Open-Angle Glaucoma

  2023cites this paper
• Proteomic analysis of human aqueous humor from fuchs uveitis syndrome.

  2023cites this paper
• AHP DB: a reference database of proteins in the human aqueous humor

  2023cites this paper
• Automated Segmentation and Morphometry of Zebrafish Anterior Chamber OCT Scans

  2023cites this paper
• Liquid-biopsy proteomics combined with AI identifies cellular drivers of eye aging and disease in vivo.

  2023cites this paper
• The Expression of Rab8, Ezrin, Radixin and Moesin in the Ciliary Body of Cynomolgus Monkeys

  2022influential citation
• Ocular Lymphatic and Glymphatic Systems: Implications for Retinal Health and Disease

  2022cites this paper
• Comprehensive Proteomic Profiling of Vitreous Humor in Ocular Sarcoidosis Compared with Other Vitreoretinal Diseases

  2022cites this paper
• Role of vasorin, an anti‐apoptotic, anti‐TGF‐β and hypoxia‐induced glycoprotein in the trabecular meshwork cells and glaucoma

  2022cites this paper
• Lab-on-a-chip technologies for minimally invasive molecular sensing of diabetic retinopathy.

  2022cites this paper
• Ocular Distribution of the Renin-Angiotensin-Aldosterone System in the Context of the SARS-CoV-2 Pandemic

  2022cites this paper
• Alzheimer’s Disease Seen through the Eye: Ocular Alterations and Neurodegeneration

  2022cites this paper
• Glial cell line-derived neurotrophic factor (GDNF) in patients with primary open-angle glaucoma and age-related cataract

  2022cites this paper
• The First Evidence on the Occurrence of Bisphenol Analogues in the Aqueous Humor of Patients Undergoing Cataract Surgery

  2022cites this paper
• Analysis of nestin protein in the aqueous humor as biomarker of open angle glaucoma

  2022cites this paper
• Where Microneedle Meets Biomarkers: Futuristic Application for Diagnosing and Monitoring Localized External Organ Diseases

  2022cites this paper
• Towards preventing exfoliation glaucoma by targeting and removing fibrillar aggregates associated with exfoliation syndrome

  2022cites this paper
• Intraocular fluid biomarkers (liquid biopsy) in human diabetic retinopathy

  2021cites this paper
• The Multi-Elemental Composition of the Aqueous Humor of Patients Undergoing Cataract Surgery, Suffering from Coexisting Diabetes, Hypertension, or Diabetic Retinopathy

  2021cites this paper
• Aqueous Humor and the Dynamics of Its Flow: Mechanisms and Routes of Aqueous Humor Drainage

  2021cites this paper
• Characterization of a dual media system for culturing primary normal and Fuchs endothelial corneal dystrophy (FECD) endothelial cells

  2021cites this paper
• Aqueous Humor Proteomic Alterations Associated with Visual Field Index Parameters in Glaucoma Patients: A Pilot Study

  2021cites this paper
• Cytokine and Growth Factor Analysis in Exfoliation Syndrome and Glaucoma

  2021cites this paper
• Elevated Cytokine Levels in Aqueous Humor Are Associated with Peripheral Anterior Synechiae after Penetrating Keratoplasty

  2021cites this paper
• Aqueous Cytokine Levels Are Associated With Progression of Peripheral Anterior Synechiae After Descemet Stripping Automated Endothelial Keratoplasty

  2021cites this paper
• Intra-population differences of apolipoproteins in the aqueous humor

  2021cites this paper
• Aqueous Cytokine Levels are Associated with Progression of Peripheral Anterior Synechiae after Descemet Stripping Automated Endothelial Keratoplasty

  2021cites this paper
• [Evaluation of aqueous cytokine levels in eyes with Fuchs endothelial corneal dystrophy and bullous keratopathy].

  2021cites this paper
• Importance of the Use of Oxidative Stress Biomarkers and Inflammatory Profile in Aqueous and Vitreous Humor in Diabetic Retinopathy

  2020cites this paper
• In‐depth proteomics approach reveals novel biomarkers of cardiac remodelling after myocardial infarction: An exploratory analysis

  2020cites this paper
• The aqueous humor proteome of primary open angle glaucoma: An extensive review.

  2020cites this paper
• Contact Lenses as Drug Delivery System for Glaucoma: A Review

  2020cites this paper
• Population Analysis of Extracellular Vesicles in Microvolumes of Biofluids

  2020cites this paper
• Local ocular renin–angiotensin–aldosterone system: any connection with intraocular pressure? A comprehensive review

  2020cites this paper
• Proteomic Study of Aqueous Humor and Its Application in the Treatment of Neovascular Glaucoma

  2020cites this paper
• Longitudinal proteomics analysis in the immediate microenvironment of islet allografts during progression of rejection.

  2020cites this paper
• Protein Biomarkers in Uveitis

  2020cites this paper
• Measuring Anterior Chamber Inflammation After Cataract Surgery: A Review of the Literature Focusing on the Correlation with Cystoid Macular Edema

  2020cites this paper
• Quantitative proteomic analysis of aqueous humor after rabbit lensectomy reveals differences in coagulation and immunomodulatory proteins.

  2020cites this paper
• Alterations of aqueous humor Aβ levels in Aβ-infused and transgenic mouse models of Alzheimer disease

  2020cites this paper
• Nerve growth factor in patients with age-related cataract

  2020cites this paper
• The Constitutive Proteome of Human Aqueous Humor and Race Specific Alterations

  2020influential citation
• Employing Flow Cytometry to Extracellular Vesicles Sample Microvolume Analysis and Quality Control

  2020cites this paper
• OPTH_A_237405 41..52

  2020cites this paper
• Mapping mRNA Expression of Glaucoma Genes in the Healthy Mouse Eye

  2019cites this paper
• Aqueous humour protein imbalances in primary open-angle glaucoma and their effects on trabecular meshwork cell function

  2019influential citation
• Evaluation of Tear Fluid and Aqueous Humor Concentration of Clusterin as Biomarkers for Early Diagnosis of Pseudoexfoliation Syndrome and Pseudoexfoliative Glaucoma

  2019cites this paper
• Multiple cytokine analyses of aqueous humor from the patients with retinitis pigmentosa.

  2019cites this paper
• The Effect of Molecular Weight on Passage of Proteins Through the Blood-Aqueous Barrier.

  2019cites this paper
• Proteomic Biomarkers of Retinal Inflammation in Diabetic Retinopathy

  2019cites this paper
• Paraoxonase 1 (PON1) promoter (−107T/C) and coding region (192Q/R and 55L/M) genetic variations in pseudoexfoliation syndrome and pseudoexfoliative glaucoma risk

  2019cites this paper
• Intraocular Biopsy and ImmunoMolecular Pathology for “Unmasking” Intraocular Inflammatory Diseases

  2019cites this paper
• Clinical Factors for Rapid Endothelial Cell Loss After Corneal Transplantation: Novel Findings From the Aqueous Humor

  2019cites this paper
• Detection of Proteins Associated with Extracellular Matrix Regulation in the Aqueous Humour of Patients with Primary Glaucoma

  2019cites this paper
• Local synthesis of hepcidin in the anterior segment of the eye: A novel observation with physiological and pathological implications.

  2019cites this paper
• Cell Biology International

  2019influential citation
• Aqueous humor's biochemical composition in ocular pathologies

  2019cites this paper
• Immune privilege in corneal transplantation.

  2019cites this paper
• Review of Biomarkers in Ocular Matrices: Challenges and Opportunities

  2019cites this paper
• Early quantitative profiling of differential retinal protein expression in lens-induced myopia in guinea pig using fluorescence difference two-dimensional gel electrophoresis

  2018cites this paper
• Advances in the analysis of “less‐conventional” human body fluids: An overview of the CE‐ and HPLC‐MS applications in the years 2015–2017

  2018cites this paper
• Brain-Derived Neurotrophic Factor in Patients with Primary Open-Angle Glaucoma and Age-related Cataract

  2018cites this paper