Avian virulence and thermostable replication of the North American strain of West Nile virus.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of General Virology

• Publication date

  2006-12-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1099/VIR.0.82299-0PMID 17098976
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Epidemiology and Transmission Dynamics of West Nile Virus Disease

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