Extrinsic cues, intrinsic cues and microfilaments regulate asymmetric protein localization in Drosophila neuroblasts.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Current Biology

• Publication date

  1997-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0960-9822(06)00370-8PMID 9382803
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• mRNA and cytoskeletal filaments.

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  1996influential reference
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  1996influential reference
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