In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications. PLGA is biocompatible and biodegradable, exhibits a wide range of erosion times, has tunable mechanical properties and most importantly, is a FDA approved polymer. In particular, PLGA has been extensively studied for the development of devices for controlled delivery of small molecule drugs, proteins and other macromolecules in commercial use and in research. This manuscript describes the various fabrication techniques for these devices and the factors affecting their degradation and drug release.
Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier.
Hirenkumar K. Makadia,S. Siegel
Published 2011 in Polymers
ABSTRACT
PUBLICATION RECORD
- Publication year
2011
- Venue
Polymers
- Publication date
2011-09-01
- Fields of study
Medicine, Materials Science, Engineering
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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- No claims are published for this paper.
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- No concepts are published for this paper.
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