Creation of phosphorylation sites in proteins: construction of a phosphorylatable human interferon alpha.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1073/PNAS.86.2.558PMID 2911594PMCID PMC286511
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Recombinant Rat and Murine Immune Interferons Are Phosphorylated at a Single Site, Ser132

  1988cited by this paper
• Human chromosomes 6 and 21 are required for sensitivity to human interferon gamma.

  1987cited by this paper
• Protein serine/threonine kinases.

  1987cited by this paper
• The mouse immune interferon receptor gene is located on chromosome 10.

  1987cited by this paper
• Interferons and their actions.

  1987cited by this paper
• Preparation of 32P-labeled murine immune interferon and its binding to the mouse immune interferon receptor.

  1986cited by this paper
• Interferon from 1981 to 1986.

  1986cited by this paper
• Phosphorylation of human immune interferon (IFN-gamma).

  1986cited by this paper
• Binding of Human Alpha-Interferons to Natural Killer Cells

  1986cited by this paper
• Sites of phosphorylation in recombinant human interferon-gamma.

  1986cited by this paper
• The gene for the human immune interferon receptor is located on chromosome 6.

  1986cited by this paper
• Interferons. Part C.

  1986cited by this paper
• Procedures for studying binding of interferon to human cells in suspension cultures.

  1986cited by this paper
• Phosphorylation of recombinant interferon-gamma by kinases released from various cells.

  1985cited by this paper
• Expression and characterization of the human c-myc DNA-binding protein

  1985cited by this paper
• Versatile expression vectors for high-level synthesis of cloned gene products in Escherichia coli.

  1985cited by this paper
• Characterization of receptors for immune interferon in U937 cells with 32P-labeled human recombinant immune interferon.

  1985cited by this paper
• Synergistic antiviral and antiproliferative activities of Escherichia coli-derived human alpha, beta, and gamma interferons

  1984cited by this paper
• Studies of the interferon receptors.

  1984cited by this paper
• The human interferons--from protein purification and sequence to cloning and expression in bacteria: before, between, and beyond.

  1983cited by this paper
• Synthesis of a human leukocyte interferon with a modified carboxy terminus in Escherichia coli.

  1983cited by this paper
• New M13 vectors for cloning.

  1983cited by this paper
• Radioactive human lymphoblastoid interferon. One-step purification, regulation of heterogeneous species production and its use for radioimmunoassay.

  1982cited by this paper
• Specific binding of human alpha interferon to a high affinity cell surface binding site on bovine kidney cells.

  1982cited by this paper
• Interferon receptors. Cross-linking of human leukocyte interferon alpha-2 to its receptor on human cells.

  1982cited by this paper
• A convenient and rapid cytopathic effect inhibition assay for interferon.

  1981cited by this paper
• Evidence that types I and II interferons have different receptors

  1981cited by this paper
• Purification and characterization of recombinant human leukocyte interferon (IFLrA) with monoclonal antibodies.

  1981cited by this paper
• Binding of 125I‐labelled human αinterferon to human lymphoid cells

  1981cited by this paper
• Development of an enzyme-linked immunosorbent assay (ELISA) for hepatitis B e antigen and antibody.

  1981cited by this paper
• Silver staining of proteins in polyacrylamide gels.

  1981cited by this paper
• Construction and identification of bacterial plasmids containing nucleotide sequence for human leukocyte interferon.

  1980cited by this paper
• High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor

  1980cited by this paper
• Role of multiple basic residues in determining the substrate specificity of cyclic AMP-dependent protein kinase.

  1977cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Design of a phosphorylatable PDZ domain with peptide-specific affinity changes.

  2013cites this paper
• Inhibition of type I and type III interferons by a secreted glycoprotein from Yaba-like disease virus

  2007cites this paper
• Protease Footprinting

  2005cites this paper
• Identifying Protein Interactions by Hydroxyl‐Radical Protein Footprinting

  2004influential citation
• Mapping protein-ligand interactions by hydroxyl-radical protein footprinting.

  2004cites this paper
• Design and construction of a phosphorylatable chimeric monoclonal antibody with a highly stable phosphate.

  2004cites this paper
• Somatic cell mapping of the bovine interferon-α receptor

  2004cites this paper
• IFN-λs mediate antiviral protection through a distinct class II cytokine receptor complex

  2003cites this paper
• IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex.

  2003cites this paper
• Generation and Characterization of Recombinant Unmodified and Phosphorylatable Murine IFN-α1 in the Methylotropic Yeast Pichia pastoris

  2003cites this paper
• Engineering and use of (32)P-labeled human recombinant interleukin-11 for receptor binding studies.

  2002cites this paper
• Site-specific 32P-labeling of cytokines, monoclonal antibodies, and other protein substrates for quantitative assays and therapeutic application.

  2002cites this paper
• Expression of Interferon Receptor Subunits, IFNAR1 and IFNAR2, in the Ovine Uterus1

  2002cites this paper
• Identification of Critical Residues in Bovine IFNAR-1 Responsible for Interferon Binding*

  2001cites this paper
• Identification, Cloning, and Characterization of a Novel Soluble Receptor That Binds IL-22 and Neutralizes Its Activity1 2

  2001cites this paper
• Identification of the Functional Interleukin-22 (IL-22) Receptor Complex

  2001cites this paper
• Neutralizes Its Activity IL-22 of a Novel Soluble Receptor That Binds Identification , Cloning , and Characterization

  2001cites this paper
• and Neutralizes Its Activity IL-22 of a Novel Soluble Receptor That Binds Identification, Cloning, and Characterization

  2001cites this paper
• Antiviral activities of the soluble extracellular domains of type I interferon receptors

  2001cites this paper
• Identification and characterization of a structural protein of hepatitis B virus: a polymerase and surface fusion protein encoded by a spliced RNA.

  2000cites this paper
• Use of phosphorylation site tags in proteins.

  2000cites this paper
• Mapping protein-protein interaction domains using ordered fragment ladder far-western analysis of hexahistidine-tagged fusion proteins.

  2000cites this paper
• IL-1 antagonist discovery

  2000cites this paper
• Domain III function of Mu transposase analysed by directed placement of subunits within the transpososome

  2000influential citation
• A high-throughput assay to identify compounds that can induce dimerization of the erythropoietin receptor.

  2000cites this paper
• Construction of phosphorylatable chimeric monoclonal antibody CC49 with a casein kinase I recognition site.

  1999cites this paper
• Introduction of protein kinase recognition sites into proteins: a review of their preparation, advantages, and applications.

  1999cites this paper
• Detection of the human hepatitis B virus X-protein in transgenic mice after radioactive labelling at a newly introduced phosphorylation site.

  1999cites this paper
• Characterization of Antihuman IFNAR-1 Monoclonal Antibodies: Epitope Localization and Functional Analysis

  1999cites this paper
• Functional dissection of DNA supercoiling factor: EF‐hand domains and C‐terminal HDEF motif are essential for its activity

  1999cites this paper
• Radiolabeling of receptor ligands by chemical incorporation of phosphorylation sites.

  1999cites this paper
• Mapping human interferon-alpha (IFN-alpha 2) binding determinants of the type I interferon receptor subunit IFNAR-1 with human/bovine IFNAR-1 chimeras.

  1998cites this paper
• Fine mapping and regulation of the association of p53 with p34cdc2

  1998cites this paper
• A simple method for site-directed mutagenesis with double-stranded plasmid DNA

  1998cites this paper
• Replication Factor C Disengages from Proliferating Cell Nuclear Antigen (PCNA) upon Sliding Clamp Formation, and PCNA Itself Tethers DNA Polymerase δ to DNA*

  1998cites this paper
• Bovine type I interferon receptor protein BoIFNAR‐1 has high‐affinity and broad specificity for human type I interferons

  1998cites this paper
• Construction of phosphorylatable chimeric monoclonal antibody CC49 with a tyrosine srC kinase recognition site.

  1998cites this paper
• Mapping protein-ligand interactions by footprinting, a radical idea.

  1998cites this paper
• Construction of phosphorylatable monoclonal antibody CC49 with a casein kinase II recognition site.

  1998cites this paper
• A simple method for site-directed mutagenesis with double-stranded plasmid DNA.

  1998cites this paper
• Construction of phosphorylatable chimeric monoclonal antibody CC49.

  1998cites this paper
• Contributions of cloned type I interferon receptor subunits to differential ligand binding 1

  1997cites this paper
• Regions of the Escherichia coli primary sigma factor σ70 that are involved in interaction with RNA polymerase core enzyme

  1997cites this paper
• Multiprotein bridging factor 1 (MBF1) is an evolutionarily conserved transcriptional coactivator that connects a regulatory factor and TATA element-binding protein.

  1997cites this paper
• Mapping conformational changes in a protein: application of a protein footprinting technique to cAMP-induced conformational changes in cAMP receptor protein.

  1997cites this paper
• Determinants for Escherichia coli RNA polymerase assembly within the β subunit

  1997cites this paper
• Determinants for Escherichia coli RNA polymerase assembly within the beta subunit.

  1997cites this paper
• Transcriptional activation through interaction of MBF2 with TFIIA

  1997cites this paper
• Determinants of RNA polymerase alpha subunit for interaction with beta, beta', and sigma subunits: hydroxyl-radical protein footprinting.

  1996cites this paper
• Differential Responsiveness of a Splice Variant of the Human Type I Interferon Receptor to Interferons*

  1996cites this paper
• Specific in vitro interaction between recombinant Strongylocentrotus purpuratus bindin and a recombinant 45A fragment of the putative bindin receptor.

  1996cites this paper
• Radioactive labeling of recombinant antibody fragments by phosphorylation using human casein kinase II and [γ-32P]-ATP

  1996cites this paper
• Purification and in vitro-phospholabeling of secretory envelope proteins E1 and E2 of hepatitis C virus expressed in insect cells.

  1996cites this paper
• Construction of phosphorylatable monoclonal antibody to a tumor-associated antigen.

  1996cites this paper
• Atypical spI Interferon Binds on Porcine Cells to a Major Component of Type I Interferon Receptor

  1995cites this paper
• Peptides Which Bind to E-selectin and Block Neutrophil Adhesion (*)

  1995cites this paper
• Interferon-alpha hybrids.

  1995cites this paper
• Reconstitution of a High Affinity Binding Site for Type I Interferons (*)

  1995cites this paper
• Radiolabeling of proteins for biochemical studies.

  1995cites this paper
• Definition of the p53 binding-site on the tms1 protein.

  1995cites this paper
• Precise mapping of the tms1 binding site on p53

  1995cites this paper
• A Generic Method for Expression and Use of “Tagged” Soluble Versions of Cell Surface Receptors

  1995cites this paper
• Mammalian DNA polymerase auxiliary proteins: analysis of replication factor C-catalyzed proliferating cell nuclear antigen loading onto circular double-stranded DNA

  1995cites this paper
• Thrombopoietin, the Mp1 ligand, is essential for full megakaryocyte development.

  1995cites this paper
• Intrinsic ligand binding properties of the human and bovine alpha-interferon receptors.

  1994cites this paper
• Expression of a functional human type I interferon receptor in hamster cells: application of functional yeast artificial chromosome (YAC) screening.

  1994cites this paper
• On the interaction of p53 with casein kinase-ii.

  1994cites this paper
• New approaches for the development and application of monoclonal antibodies for the diagnosis and therapy of human cancer.

  1994cites this paper
• A novel basic helix-loop-helix protein is expressed in muscle attachment sites of the Drosophila epidermis

  1994cites this paper
• Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions.

  1994cites this paper
• Interferon-tau and interferon-alpha interact with the same receptors in bovine endometrium. Use of a readily iodinatable form of recombinant interferon-tau for binding studies.

  1994cites this paper
• Construction and activity of phosphorylatable human interferon-alpha B2 and interferon-alpha A/D.

  1994cites this paper
• Construction and Activity of Phosphorylatable Human Interferon-αB2 and Interferon-αA/D

  1994cites this paper
• Intrinsic ligand binding properties of the human and bovine α,‐interferon receptors

  1994cites this paper
• P53 forms tight complexes with tms1 of fission yeast.

  1994cites this paper
• 32P-labeled opioid peptides with high affinity for the delta-opioid receptor.

  1993cites this paper
• Generation and screening of an oligonucleotide-encoded synthetic peptide library.

  1993cites this paper
• A simple and efficient method for site-directed mutagenesis with double-stranded plasmid DNA.

  1993cites this paper
• Generation and characterization of anti-idiotypic antibodies recognizing the interferon-alpha receptor: implications for ligand-receptor interactions.

  1993cites this paper
• Generation and Characterization of Anti-Idiotypic Antibodies Recognizing the Interferon-α Receptor: Implications for Ligand–Receptor Interactions

  1993cites this paper
• Cloning and characterization of a bovine alpha interferon receptor.

  1993cites this paper
• Receptor binding and internalization of mouse interleukin-2 derivatives that are partial agonists.

  1992cites this paper
• Interaction cloning: identification of a helix-loop-helix zipper protein that interacts with c-Fos.

  1992cites this paper
• Anti-HIV-1 Activity of Recombinant and Hybrid Species of Interferon-α

  1992cites this paper
• Somatic cell mapping of the bovine interferon-alpha receptor.

  1992cites this paper
• Phosphorylatable and epitope-tagged human erythropoietins: utility and purification of native baculovirus-derived forms.

  1992cites this paper
• The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor.

  1992cites this paper
• A novel DNA-binding motif abuts the zinc finger domain of insect nuclear hormone receptor FTZ-F1 and mouse embryonal long terminal repeat-binding protein

  1992cites this paper
• Expression of the P-protein of the human hepatitis B virus in a vaccinia virus system and detection of the nucleocapsid-associated P-gene product by radiolabelling at newly introduced phosphorylation sites.

  1992cites this paper
• A novel DNA-binding motif abuts the zinc finger domain of insect nuclear hormone receptor FTZ-F1 and mouse embryonal long terminal repeat-binding protein.

  1992cites this paper
• Anti-HIV-1 activity of recombinant and hybrid species of interferon-alpha.

  1992cites this paper
• Engineering a bioluminescent indicator for cyclic AMP-dependent protein kinase.

  1991cites this paper
• Differential modulation of two interferon-α binding proteins on a human lymphoblastoid cell line

  1991cites this paper
• Absence of the 40-kDa form of (2'-5')oligoadenylate synthetase and its corresponding mRNA from skin fibroblasts derived from Alzheimer disease patients.

  1991cites this paper
• Differential modulation of two interferon-alpha binding proteins on a human lymphoblastoid cell line.

  1991cites this paper
• Human interferon omega (omega) binds to the alpha/beta receptor.

  1991cites this paper
• Detection and Analysis of Interferon-α Receptors on Plasma Membranes and in Detergent Extracts

  1990cites this paper
• Alpha-interferon structure and natural killer cell stimulatory activity.

  1990cites this paper
• Sublocalization on chromosome 21 of human interferon-alpha receptor gene and the gene for an interferon-gamma response protein

  1990cites this paper
• Detection and analysis of interferon-alpha receptors on plasma membranes and in detergent extracts.

  1990cites this paper