Suppression of inflammatory gene expression in T cells by Porphyromonas gingivalis is mediated by targeting MAPK signaling

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Cellular & Molecular Immunology

• Publication date

  2013-07-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/cmi.2013.23PMID 23892429PMCID PMC4003196
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Altered T-Cell Responses by the Periodontal Pathogen Porphyromonas gingivalis

  2012cited by this paper
• Porphorymonas gingivalis induces intracellular adhesion molecule-1 expression in endothelial cells through the nuclear factor-kappaB pathway, but not through the p38 MAPK pathway.

  2011cited by this paper
• cytokine signaling 3 in gingival epithelial cells

  2011cited by this paper
• Porphyromonas gingivalis Induction of MicroRNA-203 Expression Controls Suppressor of Cytokine Signaling 3 in Gingival Epithelial Cells

  2011cited by this paper
• Porphyromonas gingivalis Gingipains Trigger a Proinflammatory Response in Human Monocyte-derived Macrophages Through the p38α Mitogen-activated Protein Kinase Signal Transduction Pathway

  2010cited by this paper
• Phospholipase C, p38/MAPK, and NF-κBmediated induction of MIP-3α/CCL20 by Porphyromonas gingivalis

  2009cited by this paper
• Porphyromonas gingivalis induce apoptosis in human gingival epithelial cells through a gingipain-dependent mechanism

  2009cited by this paper
• The RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Inactivate the Th2 Cytokines Interleukin-4 and Interleukin-5

  2009cited by this paper
• Regulation of alphabeta/gammadelta T cell development by the activator protein 1 transcription factor c-Jun.

  2007cited by this paper
• Periodontal Bacterial DNA Suppresses the Immune Response to Mutans Streptococcal Glucosyltransferase

  2007cited by this paper
• Regulation of αβ/γδ T Cell Development by the Activator Protein 1 Transcription Factor c-Jun1

  2007cited by this paper
• The role of T cells in periodontal disease: homeostasis and autoimmunity.

  2007cited by this paper
• CARMA1 is required for Akt-mediated NF-kappaB activation in T cells.

  2006cited by this paper
• CARMA1 Is Required for Akt-Mediated NF-κB Activation in T Cells

  2006cited by this paper
• Gene expression in splenic CD4 and CD8 cells from BALB/c mice immunized with Porphyromonas gingivalis.

  2006cited by this paper
• Mechanisms of Porphyromonas gingivalis-induced monocyte chemoattractant protein-1 expression in endothelial cells.

  2005cited by this paper
• Binding of Porphyromonas gingivalis gingipains to human CD4(+) T cells preferentially down-regulates surface CD2 and CD4 with little affect on co-stimulatory molecule expression.

  2005cited by this paper
• Porphyromonas gingivalis Bacteremia Induces Coronary and Aortic Atherosclerosis in Normocholesterolemic and Hypercholesterolemic Pigs

  2005cited by this paper
• Role of protease-activated receptor-2 in inflammation, and its possible implications as a putative mediator of periodontitis.

  2005cited by this paper
• Tethered ligand‐derived peptides of proteinase‐activated receptor 3 (PAR3) activate PAR1 and PAR2 in Jurkat T cells

  2004cited by this paper
• Degradation of Bcl10 Induced by T-Cell Activation Negatively Regulates NF-κB Signaling

  2004cited by this paper
• Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling.

  2004cited by this paper
• AP-1 subunits: quarrel and harmony among siblings

  2004cited by this paper
• Sustained exposure to bacterial antigen induces interferon-γ-dependent T cell receptor ζ down-regulation and impaired T cell function

  2003cited by this paper
• Porphyromonas gingivalis antigen preferentially stimulates T cells to express IL-17 but not receptor activator of NF-kappaB ligand in vitro.

  2003cited by this paper
• Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

  2003cited by this paper
• Sustained exposure to bacterial antigen induces interferon-gamma-dependent T cell receptor zeta down-regulation and impaired T cell function.

  2003cited by this paper
• Suppressor of Cytokine Signaling-1 Regulates Signaling in Response to Interleukin-2 and Other γc-dependent Cytokines in Peripheral T Cells*

  2003cited by this paper
• Gingipains in the culture supernatant of Porphyromonas gingivalis cleave CD4 and CD8 on human T cells.

  2002cited by this paper
• AP-1 as a regulator of cell life and death

  2002cited by this paper
• JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling.

  2001cited by this paper
• Activation of protease-activated receptors by gingipains from Porphyromonas gingivalis leads to platelet aggregation: a new trait in microbial pathogenicity.

  2001cited by this paper
• PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

  2000cited by this paper
• PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes.

  2000cited by this paper
• MAPK/ERK signaling in activated T cells inhibits CD95/Fas‐mediated apoptosis downstream of DISC assembly

  2000cited by this paper
• Multiple infections in carotid atherosclerotic plaques.

  1999cited by this paper
• p38 mitogen-activated protein kinase mediates signal integration of TCR/CD28 costimulation in primary murine T cells.

  1999cited by this paper
• SOCS-3 Is Tyrosine Phosphorylated in Response to Interleukin-2 and Suppresses STAT5 Phosphorylation and Lymphocyte Proliferation

  1999cited by this paper
• Rapid and efficient inactivation of IL-6 gingipains, lysine- and arginine-specific proteinases from Porphyromonas gingivalis.

  1999cited by this paper
• Inactivation of Tumor Necrosis Factor-α by Proteinases (Gingipains) from the Periodontal Pathogen, Porphyromonas gingivalis

  1998cited by this paper
• JNK, but not MAPK, activation is associated with Fas‐mediated apoptosis in human T cells

  1996cited by this paper
• The AP-1 site at -150 bp, but not the NF-kappa B site, is likely to represent the major target of protein kinase C in the interleukin 2 promoter

  1992cited by this paper
• CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

  1992cited by this paper
• Open Access Research Article Differential Cytokine Regulation by Nf-κb and Ap-1 in Jurkat T-cells

  year unknowncited by this paper

• Dental plaque biofilm-targeting composite nanomaterials: advances and outlook.

  2026cites this paper
• Role and Interrelationship Between Myeloid-Derived Suppressor Cells and CD4+ T Cells in Different Types of Infections: A Review

  2024cites this paper
• Past, Present and Future: The Relationship Between Circular RNA and Immunity

  2022cites this paper
• TRPM2, PDLIM5, BCL3, CD14, GBA Genes as Feasible Markers for Premature Coronary Heart Disease Risk

  2021cites this paper
• Food Contaminants Effects on an In Vitro Model of Human Intestinal Epithelium

  2021cites this paper
• Inhibition of osteoclastogenesis by opsonized Porphyromonas gingivalis

  2019cites this paper
• PKC signaling contributes to chromatin decondensation and is required for competence to respond to IL-2 during T cell activation.

  2019cites this paper
• Bioorthogonal Engineering of Bacterial Effectors for Spatial–Temporal Modulation of Cell Signaling

  2018cites this paper
• The role of toll‐like and protease‐activated receptors and associated intracellular signaling in Porphyromonas gingivalis‐infected gingival fibroblasts

  2017cites this paper
• PKC, ERK/p38 MAP kinases and NF‐κB targeted signalling play a role in the expression and release of IL‐1β and CXCL8 in Porphyromonas gingivalis‐infected THP1 cells

  2017cites this paper
• Transcriptional profiling of human smooth muscle cells infected with gingipain and fimbriae mutants of Porphyromonas gingivalis

  2016cites this paper
• Arsenic Trioxide Induces T Cell Apoptosis and Prolongs Islet Allograft Survival in Mice

  2015cites this paper
• Suppression of inflammatory responses of human gingival fibroblasts by gingipains from Porphyromonas gingivalis.

  2015cites this paper
• Inflammatory responses of gingival fibroblasts in the interaction with the periodontal pathogen Porphyromonas gingivalis

  2015cites this paper
• The role of toll-like and protease-activated receptors in the expression of cytokines by gingival fibroblasts stimulated with the periodontal pathogen Porphyromonas gingivalis.

  2015cites this paper
• Proteolytic activity of Porphyromonas gingivalis attenuates MCP-1 mRNA expression in LPS-stimulated THP-1 cells.

  2014cites this paper
• Zinc ion implantation‐deposition modification of titanium for enhanced adhesion of focal plaques of osteoblast‐like cells

  2013cites this paper