Probing the bioinorganic chemistry of toxic metals in the mammalian bloodstream to advance human health.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Inorganic Biochemistry

• Publication date

  2012-03-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.jinorgbio.2011.12.001PMID 22209021
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Is selenium deficiency really the cause of Keshan disease?

  2011cited by this paper
• Cancer research and the $90 billion metaphor.

  2011cited by this paper
• A defense of the primitive cheetah skull.

  2011cited by this paper
• Clinical studies. Trying to reset the clock on type 1 diabetes.

  2011cited by this paper
• Exposure to multiple metals from groundwater-a global crisis: geology, climate change, health effects, testing, and mitigation.

  2011cited by this paper
• Primary prevention of cancer.

  2011cited by this paper
• Liquid chromatography-inductively coupled plasma-based metallomic approaches to probe health-relevant interactions between xenobiotics and mammalian organisms.

  2011cited by this paper
• Assessing chemical risk: societies offer expertise.

  2011cited by this paper
• Probing bioinorganic chemistry processes in the bloodstream to gain new insights into the origin of human diseases.

  2010cited by this paper
• Blood selenium, glutathione peroxidase activity and antioxidant supplementation of subjects exposed to arsenic via drinking water.

  2010cited by this paper
• Circadian rhythms persist without transcription in a eukaryote

  2010cited by this paper
• Toxicology of autoimmune diseases.

  2010cited by this paper
• High selenium status in individuals exposed to arsenic through coal-burning in Shaanxi (PR of China) modulates antioxidant enzymes, heme oxygenase-1 and DNA damage.

  2010cited by this paper
• Homocysteine and holotranscobalamin and the risk of Alzheimer disease

  2010cited by this paper
• Cancer: an old disease, a new disease or something in between?

  2010cited by this paper
• Roles of dioxins and heavy metals in cancer and neurological diseases using ROS-mediated mechanisms.

  2010cited by this paper
• Selenium-dependent and -independent transport of arsenic by the human multidrug resistance protein 2 (MRP2/ABCC2): implications for the mutual detoxification of arsenic and selenium.

  2010cited by this paper
• Imaging metals in proteins by combining electrophoresis with rapid x-ray fluorescence mapping.

  2010cited by this paper
• Acute selenium toxicity associated with a dietary supplement.

  2010cited by this paper
• Selenium or No Selenium- That Is the Question in Tumor Patients: A New Controversy

  2010cited by this paper
• An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus

  2010cited by this paper
• Diseases. A medical mystery in middle China.

  2009cited by this paper
• Developmental Origins of Health and Disease: Environmental Exposures

  2009cited by this paper
• Cadmium, Environmental Exposure, and Health Outcomes

  2009cited by this paper
• One hundred years of progress in food analysis.

  2009cited by this paper
• E-waste: an assessment of global production and environmental impacts.

  2009cited by this paper
• Reversible dissolution of glutathione-mediated HgSe(x)S(1-x) nanoparticles and possible significance in Hg-Se antagonism.

  2009cited by this paper
• HPV Casts a Wider Shadow

  2009cited by this paper
• Chemical food safety issues in the United States: past, present, and future.

  2009cited by this paper
• Epigenetics: an important challenge for ICP-MS in metallomics studies

  2009cited by this paper
• Analysis of the plasma metalloproteome by SEC–ICP-AES: bridging proteomics and metabolomics

  2009cited by this paper
• Chronic toxicity of As(III) in mammals: the role of (GS)(2)AsSe(-).

  2009cited by this paper
• Prevalence of kidney dysfunction in humans - relationship to cadmium dose, metallothionein, immunological and metabolic factors.

  2009cited by this paper
• Cadmium, diabetes and chronic kidney disease.

  2009cited by this paper
• Selenoprotein P-expression, functions, and roles in mammals.

  2009cited by this paper
• A possible molecular link between the toxicological effects of arsenic, selenium and methylmercury: methylmercury(II) seleno bis(S-glutathionyl) arsenic(III)

  2008cited by this paper
• Sequential effects of daily arsenic trioxide treatment on essential and nonessential trace elements in tissues in mice

  2008cited by this paper
• Coal burning leaves toxic heavy metal legacy in the Arctic

  2008cited by this paper
• Arsenic trioxide and auranofin inhibit selenoprotein synthesis: implications for chemotherapy for acute promyelocytic leukaemia

  2008cited by this paper
• The ProteoMiner and the FortyNiners: searching for gold nuggets in the proteomic arena.

  2008cited by this paper
• A unified vision of the building blocks of life

  2008cited by this paper
• Physical Biology: 4D Visualization of Complexity

  2008cited by this paper
• Managing mercury in the great lakes: an analytical review of abatement policies.

  2007cited by this paper
• The Anthropocene: Are Humans Now Overwhelming the Great Forces of Nature

  2007cited by this paper
• Multimetal resistance and tolerance in microbial biofilms

  2007cited by this paper
• Arsenic–selenium and mercury–selenium bonds in biology

  2007cited by this paper
• Methylmercury-Induced Increase of Intracellular Ca2+ Increases Spontaneous Synaptic Current Frequency in Rat Cerebellar Slices

  2007cited by this paper
• The Journal of Nutrition Symposium: Heavy Metal Exposures in Women and Children, the Role of Nutrients Interactions between Nutrition and Environmental Exposures: Effects on Health Outcomes in Women and Children

  2007cited by this paper
• Impact of Trivalent Arsenicals on Selenoprotein Synthesis

  2006cited by this paper
• In-depth analysis of the membrane and cytosolic proteome of red blood cells.

  2006cited by this paper
• Free radicals, metals and antioxidants in oxidative stress-induced cancer.

  2006cited by this paper
• The seleno bis(S-glutathionyl) arsinium ion is assembled in erythrocyte lysate.

  2006cited by this paper
• Pro-angiogenesis action of arsenic and its reversal by selenium-derived compounds.

  2006cited by this paper
• Metals, toxicity and oxidative stress.

  2005cited by this paper
• Mercury distribution and speciation in Lake Balaton, Hungary.

  2005cited by this paper
• Mechanistic aspects of the interaction between selenium and arsenic.

  2005cited by this paper
• Mechanisms of heavy metal-induced autoimmunity.

  2005cited by this paper
• Cadmium and renal cancer.

  2005cited by this paper
• Biomonitoring. Pollution gets personal.

  2004cited by this paper
• Environmental hypothesis: is poor dietary selenium intake an underlying factor for arsenicosis and cancer in Bangladesh and West Bengal, India?

  2004cited by this paper
• Cell apoptosis induced by carcinogenic metals

  2004cited by this paper
• Pollution Gets Personal

  2004cited by this paper
• Genomic scale profiling of nutrient and trace elements in Arabidopsis thaliana

  2003cited by this paper
• Encephalopathy in megacystis-microcolon-intestinal hypoperistalsis syndrome patients on long-term total parenteral nutrition possibly due to selenium deficiency

  2003cited by this paper
• The Burden of Chronic Disease

  2003cited by this paper
• The toxicology of mercury--current exposures and clinical manifestations.

  2003cited by this paper
• Blood mercury levels in US children and women of childbearing age, 1999-2000.

  2003cited by this paper
• Review: Reactive selenium metabolites as targets of toxic metals/metalloids in mammals: a molecular toxicological perspective

  2002cited by this paper
• Trends in selenium biochemistry.

  2002cited by this paper
• Biliary excretion of [(GS)(2)AsSe](-) after intravenous injection of rabbits with arsenite and selenate.

  2002cited by this paper
• Geologic environments and health in China.

  2002cited by this paper
• Chronic arsenic poisoning from burning high-arsenic-containing coal in Guizhou, China.

  2002cited by this paper
• Synthesis, X-ray absorption spectroscopy and purification of the seleno-bis (S-glutathionyl) arsinium anion from selenide, arsenite and glutathione

  2002cited by this paper
• Identification of [(GS)2AsSe]− in rabbit bile by size‐exclusion chromatography and simultaneous multielement‐specific detection by inductively coupled plasma atomic emission spectroscopy

  2002cited by this paper
• The role of mercury in the pathogenesis of autism

  2002cited by this paper
• Carcinogenic metals and NF-kappaB activation.

  2001cited by this paper
• Recent advances in arsenic carcinogenesis: modes of action, animal model systems, and methylated arsenic metabolites.

  2001cited by this paper
• Carcinogenic metals and NF‐κB activation

  2001cited by this paper
• Arsenic trioxide, a therapeutic agent for APL

  2001cited by this paper
• Cell apoptosis induced by carcinogenic metals.

  2001cited by this paper
• Autism: a novel form of mercury poisoning.

  2001cited by this paper
• Treatment of Acute Promyelocytic Leukemia with Arsenic Trioxide

  2001cited by this paper
• Chronic heart failure and micronutrients.

  2001cited by this paper
• Cadmium carcinogenesis in review.

  2000cited by this paper
• A Metabolic Link between Arsenite and Selenite: The Seleno-bis(S-glutathionyl) Arsinium Ion

  2000cited by this paper
• Structural basis of the antagonism between inorganic mercury and selenium in mammals.

  2000cited by this paper
• Health impacts of domestic coal use in China.

  1999cited by this paper
• Binding sites for the (Hg-Se) complex on selenoprotein P.

  1998cited by this paper
• Biological interaction between transition metals (Ag, Cd and Hg), selenide/sulfide and selenoprotein P.

  1998cited by this paper
• Hormonal, environmental, and infectious risk factors for developing systemic lupus erythematosus.

  1998cited by this paper
• Enzyme activity alteration by cadmium administration to rats: the possibility of iron involvement in lipid peroxidation.

  1997cited by this paper
• Occupational exposures to metals as risk factors for Parkinson's disease

  1997cited by this paper
• Lipid peroxidation in rats administrated with mercuric chloride

  1996cited by this paper
• Four cases of selenium deficiency in postoperative long-term enteral nutrition.

  1996cited by this paper
• Toxicology of metals

  1996cited by this paper
• Calcium channels as target sites of heavy metals.

  1995cited by this paper
• Progressive encephalopathy in a Crohn's disease patient on long-term total parenteral nutrition: possible relationship to selenium deficiency.

  1994cited by this paper
• Methylmercury poisoning: Long‐term clinical, radiological, toxicological, and pathological studies of an affected family

  1994cited by this paper
• Methylmercury induces apoptosis of rat cerebellar neurons in primary culture.

  1994cited by this paper
• The epidemiology of selenium deficiency in the etiological study of endemic diseases in China.

  1993cited by this paper

• Degradation of the Vaccine Additive Thimerosal by L-Glutathione and L-Cysteine at Physiological pH

  2025cites this paper
• Toward a Mechanism-Driven Integrated Framework to Link Human Exposure to Multiple Toxic Metal(loid) Species with Environmental Diseases

  2024cites this paper
• Comparative physicochemical analysis of galvanic sludge wastes

  2023cites this paper
• Translational toxicology of metal(loid) species: linking their bioinorganic chemistry in the bloodstream to organ damage onset

  2023cites this paper
• Urinary Levels of 14 Metal Elements in General Population: A Region-Based Exploratory Study in China

  2023cites this paper
• Determinants of oxidative stress among indigenous populations in Northern Laos: Trace element exposures and dietary patterns.

  2023cites this paper
• Comparative Study of the Biochemical Response Behavior of Some Highly Toxic Minerals on Selenosis in Rats

  2021cites this paper
• Sample preparation of blood plasma enables baseline separation of iron metalloproteins by 8

  2021cites this paper
• Toxic Metal Species and ‘Endogenous’ Metalloproteins at the Blood–Organ Interface: Analytical and Bioinorganic Aspects

  2021influential citation
• Sample preparation of blood plasma enables baseline separation of iron metalloproteins by SEC-GFAAS.

  2020cites this paper
• Biological Chemistry of Toxic Metals and Metalloids, Such as Arsenic, Cadmium, and Mercury

  2020cites this paper
• Linking molecular targets of Cd in the bloodstream to organ-based adverse health effects.

  2020cites this paper
• Selenium

  2020cites this paper
• Malus micromalus Makino phenolic extract preserves hepatorenal function by regulating PKC-α signaling pathway and attenuating endoplasmic reticulum stress in lead (II) exposure mice.

  2019cites this paper
• The Role of Selenium in Arsenic and Cadmium Toxicity: an Updated Review of Scientific Literature

  2019cites this paper
• Natural antidotes and management of metal toxicity

  2019cites this paper
• Organ damage by toxic metals is critically determined by the bloodstream

  2018cites this paper
• Remarkable differences in the biochemical fate of Cd2+, Hg2+, CH3Hg+ and thimerosal in red blood cell lysate.

  2017cites this paper
• Environmentally relevant concentrations of aminopolycarboxylate chelating agents mobilize Cd from humic acid.

  2017cites this paper
• Quantum chemical approaches to [NiFe] hydrogenase.

  2017cites this paper
• Physiologically relevant plasma d,l-homocysteine concentrations mobilize Cd from human serum albumin.

  2016cites this paper
• Effects of Non-essential Metal Releases on the Environment and Human Health

  2016cites this paper
• The structural and functional effects of Hg(II) and Cd(II) on lipid model systems and human erythrocytes: A review.

  2015cites this paper
• ApoHRP-based assay to measure intracellular regulatory heme.

  2015cites this paper
• Challenges to achievement of metal sustainability in our high-tech society.

  2014cites this paper
• Grand challenges in inorganic chemistry: toward better life quality and a more sustainable world

  2013cites this paper
• Metal Species in Biology: Bottom-Up and Top-Down LC Approaches in Applied Toxicological Research

  2013cites this paper
• Neutralization by Metal Ions of the Toxicity of Sodium Selenide

  2013cites this paper