A case of conjoined twins after a transfer of a multinuclear embryo

A pregnancy with conjoined twins was observed after transfer of a multinuclear embryo. As nuclear mechanisms have a role in cellular differentiation, association between multinucleation and fetal malformations is possible. Follow‐up studies on children born after transfer of embryos with bi/multinuclear blastomeres are needed.

• Publication year

  2015

• Venue

  Clinical Case Reports

• Publication date

  2015-02-09

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/ccr3.208PMID 25914821PMCID 4405314
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011influential reference
• Blastocyst culture is associated with an elevated incidence of monozygotic twinning after single embryo transfer.

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• Conjoined twins detected in the first trimester: a review.

  2011influential reference
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  2008cited by this paper
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• Binucleated and micronucleated blastomeres in embryos derived from human assisted reproduction cycles.

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• The sonographic detection of early first‐trimester conjoined twins

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• O-191. Cleavage and morphology of embryos which are multinuclear on day 1 and normal on day 2

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• The presence of multinucleated blastomeres in human embryos is correlated with chromosomal abnormalities.

  1996cited by this paper
• Fertilization and early embryology: The presence of multinucleated blastomerés in human embryos is correlated with chromosomal abnormalities

  1996influential reference
• Early diagnosis of conjoined twins in triplet pregnancy after in vitro fertilization and assisted hatching.

  1995cited by this paper
• Conjoined twins associated with a normal singleton: very early diagnosis and successful selective termination

  1992cited by this paper
• The incidence of abnormal morphology and nucleocytoplasmic ratios in 2-, 3- and 5-day human pre-embryos.

  1991cited by this paper
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  1990cited by this paper

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