Methyl-CpG binding proteins in the nervous system

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Cell Research

• Publication date

  2005-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.cr.7290294PMID 15857580
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• The transcriptional repressor Mecp2 regulates terminal neuronal differentiation.

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• MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions.

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• EVELOPMENTAL EXPRESSION OF METHYL-CpG BINDING PROTEIN IS DYNAMICALLY REGULATED IN THE RODENT BRAIN

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• Mbd1 Is Recruited to both Methylated and Nonmethylated CpGs via Distinct DNA Binding Domains

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• Chromatin Compaction by Human MeCP2 ASSEMBLY OF NOVEL SECONDARY CHROMATIN STRUCTURES IN THE ABSENCE OF DNA METHYLATION*

  2003cited by this paper
• The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation*

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• Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis.

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• N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso.

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• Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function

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• Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3.

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• Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation.

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• Kindling induces the mRNA expression of methyl DNA-binding factors in the adult rat hippocampus.

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• Methyl‐CpG Binding Protein

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  2001cited by this paper
• Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development.

  2001cited by this paper
• DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain.

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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
• The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

  1999cited by this paper
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  1999cited by this paper
• Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

  1999cited by this paper
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  1999cited by this paper
• A mammalian protein with specific demethylase activity for mCpG DNA

  1999cited by this paper
• MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

  1999cited by this paper
• Mutation analysis

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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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