Intracellular acidosis and contractility in the normal and ischemic heart as examined by 31P NMR.

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Journal of Molecular and Cellular Cardiology

• Publication date

  1982-09-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/0022-2828(82)90124-9PMID 7143453
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The importance of the perfusion pressure in the coronary arteries for the contractility and the oxygen consumption of the heart

  2004cited by this paper
• Mechanisms of Ischemic Myocardial Cell Damage Assessed by Phosphorus‐31 Nuclear Magnetic Resonance

  1982cited by this paper
• Intracellular pH.

  1981cited by this paper
• NMR studies of tissue metabolism.

  1981cited by this paper
• Gap junctional conductance is a simple and sensitive function of intracellular pH.

  1981cited by this paper
• Analysis of rat heart in vivo by phosphorus nuclear magnetic resonance.

  1980cited by this paper
• Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance.

  1979cited by this paper
• 31P Nuclear magnetic resonance measurement of cardiac pH in perfused guinea-pig hearts.

  1979cited by this paper
• Effects of acidosis on mechanical function and Ca2+ exchange in rabbit myocardium.

  1979cited by this paper
• Phosphorus nuclear magnetic resonance studies of heart physiology

  1978cited by this paper
• Muscular fatigue investigated by phosphorus nuclear magnetic resonance

  1978cited by this paper
• Effects of acidosis and ischemia on contractility and intracellular pH of rat heart.

  1977cited by this paper
• Contraction and recovery of living muscles studied by 31p nuclear magnetic resonance

  1977cited by this paper
• Phosphorus nuclear magnetic resonance of perfused working rat hearts

  1977cited by this paper
• Phosphorus NMR studies on perfused heart.

  1977cited by this paper
• Mechanism of early "pump" failure of the ischemic heart: possible role of adenosine triphosphate depletion and inorganic phosphate accumulation.

  1977cited by this paper
• Analysis of phosphate metabolites, the intracellular pH, and the state of adenosine triphosphate in intact muscle by phosphorus nuclear magnetic resonance.

  1976cited by this paper
• Changes in Intramyocardial ST Segment Voltage and Gas Tensions with Regional Myocardial Ischemia in the Dog

  1975cited by this paper
• Observation of tissue metabolites using 31P nuclear magnetic resonance

  1974cited by this paper
• Determination of intracellular pH by 31P magnetic resonance.

  1973cited by this paper
• THE EFFECT OF CORONARY OCCLUSION ON MYOCARDIAL CONTRACTION

  1935cited by this paper

• Ca2+ Signaling in Striated Muscle Cells During Intracellular Acidosis

  2025cites this paper
• Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility

  2023cites this paper
• Myocyte Metabolic Imaging with Hyperpolarised MRI

  2018cites this paper
• Mitochondrial Calcium and Ischemia: Reperfusion Injury in Heart

  2016cites this paper
• hyperthermic conditions cardiac trabeculae under hypo-, normo-, and Frequency-dependent contractile response of isolated

  2015cites this paper
• during excitation-contraction coupling in atrial myocytes signaling 2+ Effects of mitochondrial uncoupling on Ca

  2013cites this paper
• Effects of mitochondrial uncoupling on Ca(2+) signaling during excitation-contraction coupling in atrial myocytes.

  2013cites this paper
• Regional increase of extracellular potassium leads to electrical instability and reentry occurrence through the spatial heterogeneity of APD restitution.

  2011cites this paper
• Impact of Reperfusion Injury on Heart

  2009cites this paper
• REVIEWARTICLES Physiological effects of hyperchloraemia and acidosis

  2008cites this paper
• Physiological effects of hyperchloraemia and acidosis.

  2008cites this paper
• Frequency-dependent contractile response of isolated cardiac trabeculae under hypo-, normo-, and hyperthermic conditions.

  2006cites this paper
• Regulation of Pulmonary Vascular Resistance and Blood Flow

  2006cites this paper
• Pathophysiologie des „hibernating“ und „stunned“ Myokards

  2006cites this paper
• Physiology of Ventilation During Cardiac Arrest

  2005cites this paper
• Influence of Ischemic Preconditioning on Intracellular Sodium, pH, and Cellular Energy Status in Isolated Perfused Heart

  2002cites this paper
• Enalaprilat attenuates ischemic rises in intracellular sodium in the isolated rat heart via the bradykinin receptor.

  2001cites this paper
• Hyperosmotic perfusion of the beating rat heart and the role of the Na+/K+/2CI− co-transporter and the Na+/H+ exchanger

  2000cites this paper
• Hibernating myocardium.

  1998cites this paper
• pHi and pHo at different depths in perfused myocardium measured by confocal fluorescence microscopy.

  1998cites this paper
• Chapter 3 Adenine nucleotides in cardiac cell injury and restitution

  1998cites this paper
• pHi and pHo at different depths in perfused myocardium measured by confocal fluorescence microscopy.

  1998cites this paper
• Methods of Nuclear Medicine to Verify Vitality and Efficacy of TMLR

  1998cites this paper
• Short-term reduction in dietary intake of magnesium causes deficits in brain intracellular free Mg2+ and [H+]i but not high-energy phosphates as observed by in vivo 31P-NMR.

  1997cites this paper
• Role of citrate toxicity on cardiac excitation-contraction coupling mechanisms

  1997cites this paper
• [Pathophysiology of ischemic myocardial dysfunction].

  1996cites this paper
• Utstein-style guidelines for uniform reporting of laboratory CPR research

  1996cites this paper
• Hibernating myocardium: a review.

  1996cites this paper
• Cellular response to reperfused oxygen in the postischemic myocardium.

  1996cites this paper
• Multiparameter Monitoring and Analysis of In Vivo Ischemic and Hypoxic Heart

  1996cites this paper
• Locations and mechanisms of leukocyte accumulation in the coronary microcirculation during reperfusion following ischemia

  1996cites this paper
• Beneficial vs. detrimental actions of ethanol on heart and coronary vascular muscle: roles of Mg2+ and Ca2+.

  1996cites this paper
• Consequences of brain death on myocardial metabolism: experimental study using 31P-nuclear magnetic resonance spectroscopy.

  1995cites this paper
• Role of brain [Mg2+]i in alcohol-induced hemorrhagic stroke in a rat model: a 31P-NMR in vivo study.

  1995cites this paper
• Myocardial effects of experimental acute brain death: evaluation by hemodynamic and biological studies.

  1995cites this paper
• [Potential and limitation of myocardial perfusion scintigraphy for detection of viability].

  1995cites this paper
• [Pathophysiology of the "hibernating" myocardium].

  1995cites this paper
• Preconditioning by brief ischaemic episodes in the isolated rat heart assessed by 31P NMR spectroscopy: dissociation between metabolic and functional recovery?

  1995cites this paper
• Pathophysiologie der Myokardischämie

  1995cites this paper
• Is oxygen supply sufficient to induce normoxic conditions in isolated rat heart?

  1994cites this paper
• Metabolic regulation ofin vivo myocardial contractile function: multiparameter analysis

  1994cites this paper
• Cellular Bioenergetics: Role of Coupled Creatine Kinases

  1994cites this paper
• Energetic modulation of cardiac inotropism and sarcoplasmic reticular Ca2+ uptake.

  1994cites this paper
• Characterization of hibernating and stunned myocardium.

  1994cites this paper
• Low extracellular magnesium induces intracellular free Mg deficits, ischemia, depletion of high-energy phosphates and cardiac failure in intact working rat hearts: a 31P-NMR study.

  1993cites this paper
• Sodium bicarbonate versus Carbicarb in canine myocardial hypercarbic acidosis.

  1993cites this paper
• Myofilaments: The End Effector of E-C Coupling

  1993cites this paper
• 1H-NMR spectroscopy can accurately quantitate the lipolysis and oxidation of cardiac triacylglycerols.

  1993cites this paper
• Mechanisms of pHi recovery after global ischemia in the perfused heart.

  1993cites this paper
• Excitation-Contraction Coupling and Cardiac Contractile Force

  1993cites this paper
• Crossbridge scheme and the kinetic constants of elementary steps deduced from chemically skinned papillary and trabecular muscles of the ferret.

  1993cites this paper
• [Chronic myocardial ischemia--hibernating myocardium: characteristics and limits].

  1993cites this paper
• Hypoxic preconditioning of ischaemic canine myocardium.

  1992cites this paper
• NMR Studies of Metabolism of Cells and Perfused Organs

  1992cites this paper
• Metabolic substrates can alter postischemic recovery in preconditioned ischemic heart.

  1992cites this paper
• Cardiac contractile dysfunction during mild coronary flow reductions is due to an altered calcium-pressure relationship in rat hearts.

  1992cites this paper
• Effects of Ischemia, Hypoxia, and Acidosis on Cardiac Systolic and Diastolic Function, and Glycolytic Metabolism in Normal and Hypertrophied Hearts

  1992cites this paper
• Recruitment of an Inotropic Reserve in Hibernating and Stunned Myocardium

  1992cites this paper
• [Hibernation, stunning, ischemic preconditioning--new paradigms in coronary disease?].

  1992cites this paper
• Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle.

  1992cites this paper
• Characterization of “Hibernating” and “Stunned” Myocardium with Focus on the Use of Calcium Antagonists in “Stunned” Myocardium

  1992cites this paper
• Cocaine induces intracellular free Mg deficits, ischemia and stroke as observed by in-vivo 31P-NMR of the brain.

  1992cites this paper
• Recent advances of magnetic resonance spectroscopy in myocardial ischemia

  1991cites this paper
• Effects of hypoxia and hypercapnia on the force-velocity relation of rabbit myocardium.

  1991cites this paper
• Correlations between cardiac protein synthesis rates, intracellular pH and the concentrations of creatine metabolites.

  1991cites this paper
• Acute respiratory acidosis decreases left ventricular contractility but increases cardiac output in dogs.

  1990cites this paper
• Behaviour of energy metabolites and effect of allopurinol in the "stunned" isovolumic rat heart.

  1990cites this paper
• Absence of pH changes during altered work in the in vivo sheep heart: a 31P-NMR investigation.

  1990cites this paper
• Glucose requirement for postischemic recovery of perfused working heart.

  1990cites this paper
• Effect of orthophosphate on the perfused and ischemic heart.

  1990cites this paper
• Phosphorylation of phospholamban and troponin I in the ischemic and reperfused heart: attenuation and restoration of isoprenaline responsiveness.

  1989cites this paper
• Simulated ischemia and intracellular pH in isolated ventricular muscle.

  1989cites this paper
• Adenosine-induced increase in myocardinal ATP: Are there beneficial effects for the ischaemic myocardium?

  1989cites this paper
• Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Near-complete prevention of reperfusion contractile failure.

  1989cites this paper
• Enhanced Sensitivity to Hypoxia‐Induced Diastolic Dysfunction in Pressure‐Overload Left Ventricular Hypertrophy in the Rat: Role of High‐Energy Phosphate Depletion

  1988cites this paper
• [Muscular energetics studied by nuclear magnetic resonance spectroscopy of phosphorus (cardiac and skeletal muscles)].

  1988cites this paper
• Relationships between pre-ischemic ATP and glycogen content and post-ischemic recovery of rat heart.

  1988cites this paper
• Myocardial infarction and risk region relationships: evaluation by direct and noninvasive methods.

  1988cites this paper
• Cardiac Energy Metabolism Probed with Nuclear Magnetic Resonance

  1988cites this paper
• Postischemic recovery in the stunned myocardium after reperfusion in the presence or absence of a flow-limiting coronary artery stenosis.

  1988cites this paper
• Relationship between ionic perturbations and electrophysiologic changes in a canine Purkinje fiber model of ischemia and reperfusion.

  1988cites this paper
• [Contribution of nuclear magnetic resonance spectroscopy of phosphorus-31 and carbon-13 in the study of myocardial metabolism].

  1988cites this paper
• Ischemia, High-Energy Phosphate Metabolism and Sarcomere Dynamics in Myocardium

  1988cites this paper
• Influence of local intracellular pH changes on pH and action potentials in adjacent parts of cardiac Purkinje fibers.

  1988cites this paper
• Determination of buffering capacity of rat myocardium during ischemia.

  1988cites this paper
• Cardiac ischemia. Part I--Metabolic and physiologic responses.

  1987cites this paper
• 31P nuclear magnetic resonance measurements of intracellular pH in giant barnacle muscle.

  1987cites this paper
• Mechanics of rat myocardium revisited: investigations of ultra-thin cardiac muscles under high energy demand.

  1987cites this paper
• Temporal relation between energy metabolism and myocardial function during ischemia and reperfusion.

  1987cites this paper
• Opposite initial effects of supply and demand ischemia on left ventricular diastolic compliance: the ischemia-diastolic paradox.

  1987cites this paper
• Comparative Effects of Ischemia and Hypoxia on Ventricular Relaxation in Isolated Perfused Hearts

  1987cites this paper
• Preserved high energy phosphate metabolic reserve in globally "stunned" hearts despite reduction of basal ATP content and contractility.

  1987cites this paper
• NMR Spectroscopy of the Intact Heart

  1987cites this paper
• Energy metabolism and contractile function in rat heart during graded, isovolumic perfusion using 31P nuclear magnetic resonance spectroscopy.

  1987cites this paper
• The contribution of intracellular acidosis to the decline of developed pressure in ferret hearts exposed to cyanide.

  1987cites this paper
• The effect of hypoxia on the phosphorylation of contractile and other proteins in perfused rat heart challenged by isoprenaline.

  1987cites this paper
• Acute Alterations in Diastolic Left Ventricular Chamber Distensibility: Mechanistic Differences Between Hypoxemia and Ischemia in Isolated Perfused Rabbit and Rat Hearts

  1986cites this paper
• The force-frequency relationship in rat myocardium

  1986cites this paper
• Myocardial high energy phosphate metabolism in closed chest dog: Creation of an animal model

  1986cites this paper
• A study of the effects of substrates on intracellular pH in toad ventricular strips.

  1986cites this paper