Adverse outcome pathways during zebrafish embryogenesis: a case study with paraoxon.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Aquatic Toxicology

• Publication date

  2013-01-15

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.aquatox.2012.09.008PMID 23046524
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry.

  2012cited by this paper
• Zebrafish developmental screening of the ToxCast™ Phase I chemical library.

  2012cited by this paper
• Adverse outcome pathways during early fish development: a conceptual framework for identification of chemical screening and prioritization strategies.

  2011cited by this paper
• In vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from southern Africa.

  2011cited by this paper
• Document heading doi : In vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from southern Africa

  2011cited by this paper
• Differential acetylcholinesterase inhibition of chlorpyrifos, diazinon and parathion in larval zebrafish.

  2011cited by this paper
• Chlorpyrifos-oxon disrupts zebrafish axonal growth and motor behavior.

  2011cited by this paper
• Saltatory ontogeny of fishes and sensitive early life stages for ecotoxicology tests.

  2010cited by this paper
• Subacute developmental exposure of zebrafish to the organophosphate pesticide metabolite, chlorpyrifos-oxon, results in defects in Rohon-Beard sensory neuron development.

  2010cited by this paper
• Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

  2010cited by this paper
• The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research.

  2010cited by this paper
• Regulatory aspects on the use of fish embryos in environmental toxicology

  2010cited by this paper
• Acute nicotine exposure and modulation of a spinal motor circuit in embryonic zebrafish.

  2009cited by this paper
• Small RNAs and the regulation of cis-natural antisense transcripts in Arabidopsis

  2008cited by this paper
• The zebrafish embryo model in environmental risk assessment—applications beyond acute toxicity testing

  2008cited by this paper
• Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment

  2008cited by this paper
• Enzymatic spectrophotometric method for aflatoxin B detection based on acetylcholinesterase inhibition.

  2007cited by this paper
• Animal models of human disease: zebrafish swim into view

  2007cited by this paper
• Comparison of cholin- and carboxylesterase enzyme inhibition and visible effects in the zebra fish embryo bioassay under short-term paraoxon-methyl exposure

  2006cited by this paper
• In vivo drug discovery in the zebrafish

  2005cited by this paper
• Cholin- and carboxylesterase activities in developing zebrafish embryos (Danio rerio) and their potential use for insecticide hazard assessment.

  2005cited by this paper
• Zebrafish as a model vertebrate for investigating chemical toxicity.

  2005cited by this paper
• Acetylcholinesterase function is dispensable for sensory neurite growth but is critical for neuromuscular synapse stability.

  2004cited by this paper
• Steps during the development of the zebrafish locomotor network.

  2003cited by this paper
• Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo

  2002cited by this paper
• Zebrafish Acetylcholinesterase Is Encoded by a Single Gene Localized on Linkage Group 7

  2001cited by this paper
• Synchronization of an embryonic network of identified spinal interneurons solely by electrical coupling.

  2001cited by this paper
• Motoneuron Activity Patterns Related to the Earliest Behavior of the Zebrafish Embryo

  2000cited by this paper
• Organophosphorus pesticides: do they all have the same mechanism of toxicity?

  1999cited by this paper
• Time course of the development of motor behaviors in the zebrafish embryo.

  1998cited by this paper
• Chlorpyrifos, parathion, and their oxons bind to and desensitize a nicotinic acetylcholine receptor: relevance to their toxicities.

  1997cited by this paper
• Stages of embryonic development of the zebrafish

  1995cited by this paper
• A microassay method for neurotoxic esterase determinations.

  1991cited by this paper
• Organization of hindbrain segments in the zebrafish embryo.

  1990cited by this paper
• Early expression of acetylcholinesterase activity in functionally distinct neurons of the zebrafish

  1989cited by this paper
• Identified motoneurons and their innervation of axial muscles in the zebrafish

  1986cited by this paper
• Development and axonal outgrowth of identified motoneurons in the zebrafish

  1986cited by this paper
• The development and behavioral characteristics of the startle response in the zebra fish.

  1974cited by this paper
• A new and rapid colorimetric determination of acetylcholinesterase activity.

  1961cited by this paper

• Zooplankton-Based Adverse Outcome Pathways: A Tool for Assessing Endocrine Disrupting Compounds in Aquatic Environments.

  2024cites this paper
• Zebrafish (Danio rerio): A Pioneer Model in Medical Chemical Defense Researches

  2024cites this paper
• Different developmental insecticide exposure windows trigger distinct locomotor phenotypes in the early life stages of zebrafish.

  2023cites this paper
• A mechanistic understanding of the effects of polyethylene terephthalate nanoplastics in the zebrafish (Danio rerio) embryo

  2023cites this paper
• Triphenyl phosphate-induced pericardial edema in zebrafish embryos is dependent on the ionic strength of exposure media

  2023cites this paper
• Adverse Outcome Pathways as Versatile Tools in Liver Toxicity Testing.

  2022cites this paper
• Review of ecologically relevant in vitro bioassays to supplement current in vivo tests for whole effluent toxicity testing - Part 1: Apical endpoints.

  2022cites this paper
• Toxicity of gabapentin-lactam on the early developmental stage of zebrafish (Danio rerio).

  2021cites this paper
• Triphenyl phosphate-induced pericardial edema is associated with elevated epidermal ionocytes within zebrafish embryos.

  2021cites this paper
• Concentration-dependent effects of chlorpyrifos oxon on peroxisome proliferator-activated receptor signaling in MCF-7 cells.

  2021cites this paper
• Approaches to Test the Neurotoxicity of Environmental Contaminants in the Zebrafish Model: From Behavior to Molecular Mechanisms

  2020cites this paper
• Acute exposure to environmentally relevant lead levels induces oxidative stress and neurobehavioral alterations in larval zebrafish (Danio rerio).

  2020cites this paper
• Optimization of the spontaneous tail coiling test for fast assessment of neurotoxic effects in the zebrafish embryo using an automated workflow in KNIME®.

  2020cites this paper
• Quantitative adverse outcome pathway (qAOP) models for toxicity prediction

  2020cites this paper
• Evaluation of the effects of acetylcholinesterase inhibitors in the zebrafish touch-evoked response: quantitative vs. qualitative assessment

  2020cites this paper
• Ciglitazone—a human PPARγ agonist—disrupts dorsoventral patterning in zebrafish

  2019cites this paper
• Effects of graphene oxide nanomaterial exposures on the marine bivalve, Crassostrea virginica.

  2019cites this paper
• Hypo- or hyperactivity of zebrafish embryos provoked by neuroactive substances: a review on how experimental parameters impact the predictability of behavior changes

  2019cites this paper
• Diphenyl Phosphate-Induced Toxicity During Embryonic Development.

  2019cites this paper
• Zearalenone induced embryo and neurotoxicity in zebrafish model (Danio rerio): Role of oxidative stress revealed by a multi biomarker study.

  2018cites this paper
• Diuron and diazinon alter the behavior of zebrafish embryos and larvae in the absence of acute toxicity.

  2017cites this paper
• Behavioral screening of the LOPAC1280 library in zebrafish embryos

  2017cites this paper
• The metabolite 3,4,3',4'-tetrachloroazobenzene (TCAB) exerts a higher ecotoxicity than the parent compounds 3,4-dichloroaniline (3,4-DCA) and propanil.

  2016cites this paper
• In Silico Methods for Predicting Drug Toxicity

  2016cites this paper
• Adverse Outcome Pathways as Tools to Assess Drug-Induced Toxicity.

  2016cites this paper
• Zebrafish as a model for acetylcholinesterase‐inhibiting organophosphorus agent exposure and oxime reactivation

  2016cites this paper
• Advancing Toxicology Research Using In Vivo High Throughput Toxicology with Small Fish Models

  2016cites this paper
• Corrigendum: Zebrafish Models for Human Acute Organophosphorus Poisoning

  2016cites this paper
• Zebrafish Models for Human Acute Organophosphorus Poisoning

  2015cites this paper
• Adverse outcome pathway: Framework, application, and challenges in chemical risk assessment.

  2015cites this paper
• Zebrafish as a model for toxicological studies: is there a role for Paraoxonase?

  2015cites this paper
• Zebrafish as a model for toxicological studies: is there a role for Paraoxonase?

  2015cites this paper
• Molecular Bioindicators of Pollution in Fish

  2015cites this paper
• Comparability of behavioural assays using zebrafish larvae to assess neurotoxicity

  2015cites this paper
• In vitro approaches for detection of chemical sensitization.

  2014cites this paper
• High-content screening assay for identification of chemicals impacting spontaneous activity in zebrafish embryos.

  2014cites this paper
• Breakdown of the Molecular Processes Driving the Adverse Outcome Pathways (AOPs) of Skin and Respiratory Sensitization Induction in Humans Exposed to Xenobiotics and Proteins

  2014cites this paper
• Identification of metabolic pathways in Daphnia magna explaining hormetic effects of selective serotonin reuptake inhibitors and 4-nonylphenol using transcriptomic and phenotypic responses.

  2013cites this paper
• Adverse Outcome Pathways: A framework for Identifying Chemical Mode of Action During Zebrafish Embryogenesis

  2013cites this paper
• The adverse outcome pathway concept: a pragmatic tool in toxicology.

  2013cites this paper
• Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor.

  2013cites this paper
• High-content screening assay for identification of chemicals impacting cardiovascular function in zebrafish embryos.

  2013cites this paper