Heterogeneous Patterns of CEBPα Mutation Status in the Progression of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia to Acute Myelogenous Leukemia

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Clinical Cancer Research

• Publication date

  2005-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1158/1078-0432.CCR-04-1932
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations.

  2004cited by this paper
• Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia

  2004cited by this paper
• Internal tandem duplication of fms‐like tyrosine kinase 3 is associated with poor outcome in patients with myelodysplastic syndrome

  2004cited by this paper
• Evidence for allelic evolution of C/EBPalpha mutations in acute myeloid leukaemia

  2003cited by this paper
• Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML.

  2003cited by this paper
• The emergence of a C/EBPα mutation in the clonal evolution of MDS towards secondary AML

  2003influential reference
• Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein a in myelodysplastic syndromes and acute myeloid leukemias

  2002influential reference
• Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias.

  2002cited by this paper
• Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse.

  2002cited by this paper
• Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia

  2001influential reference
• The World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. Report of the Clinical Advisory Committee meeting, Airlie House, Virginia, November, 1997.

  1999cited by this paper
• World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997.

  1999cited by this paper
• Clonal development of myeloproliferative disorders: clues to hematopoietic differentiation and multistep pathogenesis of cancer

  1998cited by this paper
• Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression.

  1998cited by this paper
• CCAAT/Enhancer Binding Protein α Is a Regulatory Switch Sufficient for Induction of Granulocytic Development from Bipotential Myeloid Progenitors

  1998cited by this paper
• International scoring system for evaluating prognosis in myelodysplastic syndromes.

  1997cited by this paper
• Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice.

  1997cited by this paper
• Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoïesis and a high incidence of P53 mutations.

  1995cited by this paper
• TP53 mutations emerge at early phase of myelodysplastic syndrome and are associated with complex chromosomal abnormalities.

  1995cited by this paper
• A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells.

  1992cited by this paper
• The CCAAT/enhancer binding protein (C/EBPα) gene (CEBPA) maps to human chromosome 19q13.1 and the related nuclear factor NF-IL6 (C/EBPβ) gene (CEBPB) maps to human chromosome 20q13.1

  1992cited by this paper
• Isolation of a recombinant copy of the gene encoding C/EBP.

  1988cited by this paper
• Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

  1987cited by this paper
• Myelodysplastic syndromes: natural history and features of prognostic importance.

  1986cited by this paper
• Proposals for the classification of the myelodysplastic syndromes

  1982cited by this paper

• The Genetic Landscape of Myelodysplastic Neoplasm Progression to Acute Myeloid Leukemia

  2023cites this paper
• The Interpretation of Sequence Variants in Myeloid Neoplasms.

  2021cites this paper
• Clinical Significance of DNA Variants in Chronic Myeloid Neoplasms: A Report of the Association for Molecular Pathology.

  2018cites this paper
• A systems approach for the elucidation of crucial genes and network constituents of cervical intraepithelial neoplasia 1 (CIN1).

  2017cites this paper
• A clinical grade sequencing-based assay for CEBPA mutation testing: report of a large series of myeloid neoplasms.

  2015cites this paper
• Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable

  2015cites this paper
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  2015cites this paper
• Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations

  2014cites this paper
• Gene Mutation Patterns in Patients with Minimally Differentiated Acute Myeloid Leukemia☆

  2014cites this paper
• CEBPA (CCAAT enhancer binding protein alpha)

  2011cites this paper
• Myelodysplastic/myeloproliferative neoplasms.

  2011cites this paper
• Two types of C/EBPα mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models.

  2011cites this paper
• Prognostic Significance of CEBPAMutations and BAALC Expression in AcuteMyeloid Leukemia Patients with NormalKaryotype

  2010influential citation
• Transcription factor mutations in myelodysplastic/myeloproliferative neoplasms

  2010cites this paper
• C/EBPα in leukemogenesis: Identity and origin of the leukemia‐initiating cell

  2009cites this paper
• RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation

  2009cites this paper
• Dysregulation of the C/EBPalpha differentiation pathway in human cancer.

  2009cites this paper
• Transcription Factors in Cancer Stem Cells of the Hematopoietic Lineage

  2009cites this paper
• Mutation of C/EBPalpha predisposes to the development of myeloid leukemia in a retroviral insertional mutagenesis screen.

  2008cites this paper
• Growth-inhibiting activity of transcription factor C/EBPalpha, its role in haematopoiesis and its tumour suppressor or oncogenic properties in leukaemias.

  2007cites this paper
• Growth-inhibiting Activity of Transcription Factor C/EBPα, Its Role in Haematopoiesis and Its Tumour Suppressor or Oncogenic Properties in Leukaemias (C/EBPα / cell cycle / proliferation / differentiation / haematopoiesis / leukaemia / tumour suppressor)

  2007cites this paper
• C/EBPα: A tumour suppressor in multiple tissues?

  2006cites this paper
• Cytogenetic Diagnosis of Myelodysplastic Syndromes

  2006cites this paper
• AML patients with CEBPα mutations mostly retain identical mutant patterns but frequently change in allelic distribution at relapse: a comparative analysis on paired diagnosis and relapse samples

  2006cites this paper
• Mutational analysis of the KIT gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia.

  2006cites this paper