Cocaine Cues and Dopamine in Dorsal Striatum: Mechanism of Craving in Cocaine Addiction

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Neuroscience

• Publication date

  2006-06-14

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1523/JNEUROSCI.1544-06.2006PMID 16775146PMCID PMC6674019
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neural correlates of high and craving during cocaine self-administration using BOLD fMRI

  2005cited by this paper
• Neural activity associated with stress-induced cocaine craving: a functional magnetic resonance imaging study

  2005cited by this paper
• The neural basis of addiction: a pathology of motivation and choice.

  2005cited by this paper
• Involvement of the Dorsal Striatum in Cue-Controlled Cocaine Seeking

  2005cited by this paper
• Differential Involvement of Orbitofrontal Cortex Subregions in Conditioned Cue-Induced and Cocaine-Primed Reinstatement of Cocaine Seeking in Rats

  2004cited by this paper
• Dopamine in drug abuse and addiction: results from imaging studies and treatment implications

  2004cited by this paper
• Direct Interactions between the Basolateral Amygdala and Nucleus Accumbens Core Underlie Cocaine-Seeking Behavior by Rats

  2004cited by this paper
• Cocaine Self-Administration Produces a Progressive Involvement of Limbic, Association, and Sensorimotor Striatal Domains

  2004cited by this paper
• Subsecond dopamine release promotes cocaine seeking

  2003cited by this paper
• “Nonhedonic” food motivation in humans involves dopamine in the dorsal striatum and methylphenidate amplifies this effect

  2002cited by this paper
• Dopamine Release in the Dorsal Striatum during Cocaine-Seeking Behavior under the Control of a Drug-Associated Cue

  2002cited by this paper
• 110 NEUROIMAGING OF COCAINE CRAVING STATES : CESSATION , STIMULANT ADMINISTRATION , AND DRUG CUE PARADIGMS

  2002cited by this paper
• Cocaine withdrawal severity and urine toxicology results from treatment entry predict outcome in medication trials for cocaine dependence.

  2002cited by this paper
• Multiple parallel memory systems in the brain of the rat.

  2002cited by this paper
• Progression of Changes in Dopamine Transporter Binding Site Density as a Result of Cocaine Self-Administration in Rhesus Monkeys

  2001cited by this paper
• Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens.

  2000influential reference
• Conditioned increases in behavioral activity and accumbens dopamine levels produced by intravenous cocaine.

  2000cited by this paper
• Dissociation in Conditioned Dopamine Release in the Nucleus Accumbens Core and Shell in Response to Cocaine Cues and during Cocaine-Seeking Behavior in Rats

  2000cited by this paper
• Impact of Self-Administered Cocaine and Cocaine Cues on Extracellular Dopamine in Mesolimbic and Sensorimotor Striatum in Rhesus Monkeys

  2000cited by this paper
• Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli.

  2000cited by this paper
• Association of methylphenidate-induced craving with changes in right striato-orbitofrontal metabolism in cocaine abusers: implications in addiction.

  1999cited by this paper
• Drug addiction: bad habits add up

  1999cited by this paper
• Limbic activation during cue-induced cocaine craving.

  1999cited by this paper
• Conditioning factors in drug abuse: can they explain compulsion?

  1998cited by this paper
• Reliability and validity of the Cocaine Selective Severity Assessment.

  1998cited by this paper
• Acute effects of cocaine on human brain activity and emotion.

  1997cited by this paper
• Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method.

  1997cited by this paper
• A Neural Substrate of Prediction and Reward

  1997cited by this paper
• The primate substantia nigra and VTA: integrative circuitry and function.

  1997cited by this paper
• Dopamine Overflow in the Nucleus Accumbens during Extinction and Reinstatement of Cocaine Self-Administration Behavior

  1996influential reference
• Conditioned changes in nucleus accumbens dopamine signal established by intravenous cocaine in rats.

  1996influential reference
• Effects of Blood Flow on [11C]Raclopride Binding in the Brain: Model Simulations and Kinetic Analysis of PET Data

  1994cited by this paper
• Drug- and behavior-associated changes in dopamine-related electrochemical signals during intravenous cocaine self-administration in rats

  1994cited by this paper
• Imaging endogenous dopamine competition with [11C]raclopride in the human brain

  1994cited by this paper
• The basal ganglia and adaptive motor control.

  1994cited by this paper
• Statistical parametric maps in functional imaging: A general linear approach

  1994influential reference
• Reproducibility of repeated measures of carbon-11-raclopride binding in the human brain.

  1993cited by this paper
• The development of a cocaine craving questionnaire.

  1993cited by this paper
• Cocaine-induced conditioned locomotion: absence of associated increases in dopamine release.

  1992cited by this paper
• The Fifth Edition of the Addiction Severity Index.

  1992cited by this paper
• Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [N-11C-Methyl]-(−)-Cocaine PET Studies in Human Subjects

  1990cited by this paper
• A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes.

  1990influential reference
• Brain dopamine and reward.

  1989cited by this paper
• Cellular and molecular mechanisms of drug dependence.

  1988cited by this paper
• Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

  1988cited by this paper

• Chemogenetic regulation of direct and indirect pathway neurons in the dorsomedial striatum reshapes cocaine-induced conditioned place preference behaviors in mice.

  2026cites this paper
• Brain imaging correlates of food addiction: A systematic review with methodological recommendations.

  2026cites this paper
• Cocaine Cues Used in Experimental Research: A Systematic Review

  2025cites this paper
• Mu opioid receptors expressed in striatal D2 medium spiny neurons have divergent contributions to cocaine and morphine reward

  2025cites this paper
• Cue-induced Magnetic Resonance Spectroscopy of Glutamate in Addiction Research: Current Evidence, Pros, and Cons

  2025cites this paper
• A single-center case-control study of the association between dorsal striatal damage and nicotine addiction

  2025cites this paper
• Causal Mechanisms of Monoamine Transporter Phosphorylation.

  2025cites this paper
• A Roadmap for Transformative Translational Research on Gambling Disorder in the UK Funded by A New Levy on The Gambling Industry.

  2025cites this paper
• Cortico-striatal action control inherent of opponent cognitive-motivational styles

  2025cites this paper
• PKD1-mediated phosphorylation at dopamine D2 receptor serine 365 site in dorsal striatum underlies cocaine-induced locomotor hyperactivity

  2025cites this paper
• Linking Motor Impulsivity to Cue-Induced Craving and Central Beta Oscillations in Individuals with Methamphetamine Use Disorder.

  2025cites this paper
• Adverse Drug Reactions Associated with Concomitant Use of Calcium Channel Blockers and Cocaine: An Analysis of FDA Adverse Events Reporting System Data

  2025cites this paper
• Biphasic Model of Addiction: Neurobehavioral Adaptations

  2025cites this paper
• Induction of more severe central sensitization in a medication overuse headache model mice through active ingestion of rizatriptan

  2025cites this paper
• Psychedelics as pharmacotherapeutics for substance use disorders: a scoping review on clinical trials and perspectives on underlying neurobiology

  2025cites this paper
• Semaglutide suppresses cocaine taking, seeking, and cocaine-evoked dopamine levels in the nucleus accumbens.

  2025influential citation
• Reduced GIRK expression in midbrain dopamine neurons during prolonged abstinence from fentanyl self-administration

  2025cites this paper
• Delta opioid receptor activation influences responding to earn cocaine-associated cues in the New Response Acquisition procedure.

  2025cites this paper
• Moving Beyond Self-Report in Characterizing Drug Addiction: Using Drug-Biased Behavior to Predict Treatment Completion and Dropout in Heroin-Primary, Medication-Maintained Opioid Use Disorder

  2025cites this paper
• Dopamine receptor sensitivity and Pavlovian conditioned approach

  2025cites this paper
• Dopamine receptor sensitivity and Pavlovian conditioned approach

  2025cites this paper
• The Effect and Mechanism of Magnesium Valproate on Methamphetamine‐Addicted Rats

  2025cites this paper
• Abstinence and extinction drive opposing changes in striatal activity and dopamine signaling during alcohol relapse.

  2025cites this paper
• The left-most digit change induces a decrease in brain activity related to visuospatial processing: An fMRI study of the price ending effect.

  2025cites this paper
• Increased Mesostriatal Intrinsic Connectivity Associated With Cue Exposure in Adult Cannabis Users: Preliminary Findings

  2025cites this paper
• Striatal cue-reactivity and neurotransmitter function in gambling disorder

  2025influential citation
• Changes in dorsomedial striatum activity during expression of goal-directed vs. habit-like cue-induced cocaine seeking

  2024cites this paper
• Dysregulation of dopamine neurotransmission in drug addicts: implications for criminal behavior and corrective interventions

  2024cites this paper
• IUPHAR THEMED ISSUE: New Strategies for Medications to Treat Substance Use Disorders.

  2024cites this paper
• Pan‐striatal reduction in the expression of the astrocytic dopamine transporter precedes the development of dorsolateral striatum dopamine‐dependent incentive heroin seeking habits

  2024cites this paper
• Acting with awareness is positively correlated with dorsal anterior cingulate cortex glutamate concentration but both are impaired in Internet gaming disorder.

  2024cites this paper
• The Limbic System in Co-Occurring Substance Use and Anxiety Disorders: A Narrative Review Using the RDoC Framework

  2024cites this paper
• Intrinsic Functional Connectivity between the Anterior Insular and Retrosplenial Cortex as a Moderator and Consequence of Cocaine Self-Administration in Rats

  2024cites this paper
• Biomarkers of Internet Gaming Disorder—A Narrative Review

  2024cites this paper
• Food Addiction

  2024cites this paper
• Brain alterations in individuals with exercise dependence: A multimodal neuroimaging investigation

  2024cites this paper
• The Neurocircuitry of Substance Use Disorder, Treatment, and Change: A Resource for Clinical Psychiatrists.

  2024cites this paper
• Brain structural differences in cocaine use disorder: Insights from multivariate and neurotransmitter analyses.

  2024cites this paper
• Associative memory in alcohol-related contexts: An fMRI study with young binge drinkers

  2024cites this paper
• Gut Hormones: Possible Mediators of Addictive Disorders?

  2024cites this paper
• Neuroimaging biomarkers of addiction

  2024cites this paper
• Sex differences in dorsal striatal volume and interest in quitting smoking.

  2024cites this paper
• Abnormal Granger causal connectivity based on altered gray matter volume and associated neurotransmitters of adolescents with internet gaming disorder revealed by a multimodal neuroimaging study

  2024cites this paper
• Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment

  2024cites this paper
• Comprehensive Glycomic and Proteomic Analysis of Mouse Striatum and Lateral Hypothalamus Following Repeated Exposures to Cocaine or Methamphetamine

  2024cites this paper
• The neuropharmacological properties of α‐pyrrolidinobutiothiophenone, a new synthetic cathinone, in rodents; role of the dopaminergic system

  2024cites this paper
• The Incentive-Sensitization Theory of Addiction 30 Years On

  2024cites this paper
• Mapping the Neural Substrates of Cocaine Craving: A Systematic Review

  2024influential citation
• DIETARY REGULATION OF SILENT SYNAPSES IN THE DORSOLATERAL STRIATUM

  2024influential citation
• Effects of chronic naltrexone treatment on relapse-related behavior and neural responses to fentanyl in awake nonhuman primates

  2024cites this paper
• A multimodal neuroimaging study of youth at risk for substance use disorders: Functional magnetic resonance imaging and [ 18F]fallypride positron emission tomography

  2024cites this paper
• Evaluation of (S)-T1 and (S)-T2 ligands targeting α3β4 nAChR as potential nicotine addiction pharmacotherapy

  2024cites this paper
• Brain connectivity changes to fast versus slow dopamine increases

  2024cites this paper
• Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial

  2024cites this paper
• Amphetamine use disorder is associated with striatum hypoactivation during anticipation of loss and reward

  2024cites this paper
• Cortico-striatal action control inherent of opponent cognitive-motivational styles

  2024cites this paper
• Ameliorating effects of Acanthopanax koreanum extract and components on nicotine dependence and withdrawal symptoms

  2024cites this paper
• Re-evaluating our focus in addiction: emotional dysregulation is a critical driver of relapse to drug use

  2024cites this paper
• Neural correlates of chocolate brand preference: A functional MRI study

  2024cites this paper
• Neural circuit selective for fast but not slow dopamine increases in drug reward

  2023cites this paper
• The influence of dopamine autoreceptors on temperament and addiction risk.

  2023cites this paper
• Substance Use Disorders: Basic Overview for the Anesthesiologist

  2023cites this paper
• cAMP-mediated upregulation of HCN channels in VTA dopamine neurons promotes cocaine reinforcement

  2023cites this paper
• Methylphenidate as a treatment option for substance use disorder: a transdiagnostic perspective

  2023cites this paper
• Brain responses to positive and negative events in individuals with internet gaming disorder during real gaming

  2023cites this paper
• Subregion specific neuroadaptations in the female rat striatum during acute and protracted withdrawal from nicotine

  2023cites this paper
• Changes in dorsomedial striatum activity mediate expression of goal-directed vs. habit-like cue-induced cocaine seeking

  2023cites this paper
• Potential effect of antidepressants on remission from cocaine use disorder - A nationwide matched retrospective cohort study.

  2023cites this paper
• Relapse Prevention and Prediction Strategies in Substance Use Disorder

  2023cites this paper
• Cocaine use disorder patients develop distinct patterns of regulation of acth secretion by a vasopressin agonist and oxytocin: Report on a laboratory study

  2023cites this paper
• The Stage-Based Model of Addiction—Using Drosophila to Investigate Alcohol and Psychostimulant Responses

  2023cites this paper
• Resting-State Functional Connectivity of the Dorsal and Ventral Striatum, Impulsivity, and Severity of Use in Recently Abstinent Cocaine-Dependent Individuals

  2023cites this paper
• BIASED ATTENTIONAL PROCESSING ASSOCIATED WITH CONCURRENT DISORDERS: AN EVENT-RELATED POTENTIAL STUDY

  2023cites this paper
• The traps of adaptation: Addiction as maladaptive referent-dependent evaluation

  2023cites this paper
• Mixed amphetamine salts-extended release (MAS-ER) as a behavioral treatment augmentation strategy for cocaine use disorder: A randomized clinical trial.

  2023cites this paper
• Potential Biological Markers and Treatment Implications for Binge Eating Disorder and Behavioral Addictions

  2023cites this paper
• The Role of Physical Exercise in Opioid Substitution Therapy: Mechanisms of Sequential Effects

  2023cites this paper
• Electrophysiological signature of the interplay between habits and inhibition in response to smoking‐related cues in individuals with a smoking habit: An event‐related potential study

  2023cites this paper
• Cognitive domain-independent aberrant frontoparietal network strength in individuals with excessive smartphone use.

  2023cites this paper
• Blunted Expected Reward Value Signals in Binge Alcohol Drinkers

  2023influential citation
• Neuroplastic Changes in Addiction Memory—How Music Therapy and Music-Based Intervention May Reduce Craving: A Narrative Review

  2023cites this paper
• Striatal hypoactivation during monetary loss anticipation in individuals with substance use disorders in a heterogenous urban American Indian sample

  2023cites this paper
• A novel hypothalamic-midbrain circuit for model-based learning

  2023cites this paper
• Development of Chinese food picture library for inducing food cravings

  2023cites this paper
• Negative impact of daily screen use on inhibitory control network in preadolescence: A two-year follow-up study

  2023cites this paper
• Amphetamine-induced prolonged disturbances in tissue levels of dopamine and serotonin in the rat brain

  2023cites this paper
• Mesocorticolimbic function in cocaine polydrug users: A multimodal study of drug cue reactivity and cognitive regulation

  2023cites this paper
• A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus

  2022cites this paper
• Acute and protracted abstinence from methamphetamine bidirectionally changes intrinsic excitability of indirect pathway spiny projection neurons in the dorsomedial striatum

  2022cites this paper
• The Role of Unawareness, Volition, and Neural Hyperconnectivity in Alcohol Use Disorder: A Functional Magnetic Resonance Imaging Study.

  2022cites this paper
• Future Newborns with Opioid-Induced Neonatal Abstinence Syndrome (NAS) Could Be Assessed with the Genetic Addiction Risk Severity (GARS) Test and Potentially Treated Using Precision Amino-Acid Enkephalinase Inhibition Therapy (KB220) as a Frontline Modality Instead of Potent Opioids

  2022cites this paper
• Natural Products for the Treatment of Drug Addiction: Narrative Review

  2022cites this paper
• Common and distinct fronto-striatal volumetric changes in heroin and cocaine use disorders.

  2022cites this paper
• A multivariate regressor of patterned dopamine release predicts relapse to cocaine

  2022cites this paper
• Electrophysiological signature of the interplay between habits and inhibition in response to smoking-related cues in individuals with a smoking habit: an ERP study

  2022cites this paper
• Sign‐tracking modulates reward‐related neural activation to reward cues, but not reward feedback

  2022cites this paper
• Reciprocal modulation between cigarette smoking and internet gaming disorder on participation coefficient within functional brain networks

  2022cites this paper
• Epac2 in midbrain dopamine neurons contributes to cocaine reinforcement via enhancement of dopamine release

  2022cites this paper
• A Novel and Selective Dopamine Transporter Inhibitor, (S)-MK-26, Promotes Hippocampal Synaptic Plasticity and Restores Effort-Related Motivational Dysfunctions

  2022cites this paper
• Abnormal brain networks related to drug and non-drug reward anticipation and outcome processing in stimulant use disorder: A functional connectomics approach.

  2022cites this paper