Targeting the translation machinery in cancer

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Nature reviews. Drug discovery

• Publication date

  2015-03-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/nrd4505PMID 25743081
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Glimpses of the near future: a new generation of mTOR inhibitors.

  2017cited by this paper
• Next Generation

  2016cited by this paper
• Virus-like particle-mediated intracellular delivery of mRNA cap analog with in vivo activity against hepatocellular carcinoma.

  2015cited by this paper
• Mnk kinases in cytokine signaling and regulation of cytokine responses

  2015cited by this paper
• Transcriptome-wide characterization of the eIF4A signature highlights plasticity in translation regulation

  2014cited by this paper
• Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

  2014cited by this paper
• Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents.

  2014cited by this paper
• First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines

  2014cited by this paper
• Decreased Expression of EIF4A1 After Preoperative Brachytherapy Predicts Better Tumor-Specific Survival in Cervical Cancer

  2014cited by this paper
• Oxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.

  2014cited by this paper
• Metformin and Cancer: Mounting Evidence Against an Association

  2014cited by this paper
• Pancreatic tumours escape from translational control through 4E-BP1 loss

  2014cited by this paper
• Resistance to mTOR Kinase Inhibitors in Lymphoma Cells Lacking 4EBP1

  2014cited by this paper
• Discovery of 5‐(2‐(Phenylamino)pyrimidin‐4‐yl)thiazol‐2(3H)‐one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation

  2014cited by this paper
• Translation factors and ribosomal proteins control tumor onset and progression: how?

  2014cited by this paper
• Simplified Silvestrol Analogues with Potent Cytotoxic Activity

  2014cited by this paper
• Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation

  2014cited by this paper
• RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

  2014cited by this paper
• Intrinsic and acquired resistance to MEK1/2 inhibitors in cancer.

  2014cited by this paper
• eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies

  2014cited by this paper
• Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e

  2014cited by this paper
• The scanning mechanism of eukaryotic translation initiation.

  2014cited by this paper
• Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

  2014cited by this paper
• Phosphorylated Mnk1 and eIF4E Are Associated with Lymph Node Metastasis and Poor Prognosis of Nasopharyngeal Carcinoma

  2014cited by this paper
• Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′TOP mRNA translation

  2014cited by this paper
• Coupling 40 S ribosome recruitment to modification of a cap-binding initiation factor by eIF 3 subunit e

  2014cited by this paper
• PI3K and cancer: lessons, challenges and opportunities

  2014cited by this paper
• Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer.

  2014cited by this paper
• MAP kinase-interacting kinases--emerging targets against cancer.

  2014cited by this paper
• Attenuation of malignant phenotypes of breast cancer cells through eIF2α-mediated downregulation of Rac1 signaling.

  2014cited by this paper
• The intra-tumor heterogeneity of cell signaling factors in breast cancer: p4E-BP1 and peIF4E are diffusely expressed and are real potential targets

  2014cited by this paper
• Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G

  2014cited by this paper
• Talks about TORCs: recent advancesin target of rapamycin signalling. On mTOR nomenclature.

  2013cited by this paper
• Gemcitabine triggers a pro-survival response in pancreatic cancer cells through activation of the MNK2/eIF4E pathway

  2013cited by this paper
• Growth control and ribosomopathies.

  2013cited by this paper
• Translation of viral mRNAs that do not require eIF4E is blocked by the inhibitor 4EGI-1

  2013cited by this paper
• Efficacy of the investigational mTOR kinase inhibitor MLN0128/INK128 in models of B-cell acute lymphoblastic leukemia

  2013cited by this paper
• Evidence for a functionally relevant rocaglamide binding site on the eIF4A-RNA complex.

  2013cited by this paper
• mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

  2013cited by this paper
• Tinkering with translation: protein synthesis in virus-infected cells.

  2013cited by this paper
• Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A

  2013cited by this paper
• Treatment of breast and lung cancer cells with a N-7 benzyl guanosine monophosphate tryptamine phosphoramidate pronucleotide (4Ei-1) results in chemosensitization to gemcitabine and induced eIF4E proteasomal degradation.

  2013cited by this paper
• Potential applications for biguanides in oncology.

  2013cited by this paper
• Control of oncogenesis by eIF2α phosphorylation: implications in PTEN and PI3K-Akt signaling and tumor treatment.

  2013cited by this paper
• Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis

  2013cited by this paper
• Rapamycin resistance: mTORC1 substrates hold some of the answers.

  2013cited by this paper
• mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.

  2013cited by this paper
• Talks About TORCs: Recent Advances in Target of Rapamycin Signalling

  2013cited by this paper
• mTOR kinase structure, mechanism and regulation by the rapamycin-binding domain

  2013cited by this paper
• Cap-Translation Inhibitor, 4EGI-1, Restores Sensitivity to ABT-737 Apoptosis through Cap-Dependent and -Independent Mechanisms in Chronic Lymphocytic Leukemia

  2013cited by this paper
• Everolimus long-term safety and efficacy in subependymal giant cell astrocytoma

  2013cited by this paper
• The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in acute myeloid leukemia

  2013cited by this paper
• Anti-oncogenic potential of the eIF4E-binding proteins

  2013cited by this paper
• Post‐transcriptional regulatory networks in immunity

  2013cited by this paper
• Hypoxia-inducible Factor-1α (HIF-1α) Promotes Cap-dependent Translation of Selective mRNAs through Up-regulating Initiation Factor eIF4E1 in Breast Cancer Cells under Hypoxia Conditions*

  2013cited by this paper
• LARP1 specifically recognizes the 3′ terminus of poly(A) mRNA

  2013cited by this paper
• Sequential administration of methotrexate and asparaginase in relapsed or refractory pediatric acute myeloid leukemia

  2013cited by this paper
• Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity

  2013cited by this paper
• Targeting the unfolded protein response in disease

  2013cited by this paper
• Toward a genome-wide landscape of translational control.

  2013cited by this paper
• Rational Design of Resorcylic Acid Lactone Analogues as Covalent MNK1/2 Kinase Inhibitors by Tuning the Reactivity of an Enamide Michael Acceptor

  2013cited by this paper
• Dynamic recognition of the mRNA cap by Saccharomyces cerevisiae eIF4E.

  2013cited by this paper
• Results of an international randomized phase III trial of the mammalian target of rapamycin inhibitor ridaforolimus versus placebo to control metastatic sarcomas in patients after benefit from prior chemotherapy.

  2013cited by this paper
• Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors.

  2012cited by this paper
• Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53.

  2012cited by this paper
• MKNK1 is a YB-1 target gene responsible for imparting trastuzumab resistance and can be blocked by RSK inhibition

  2012cited by this paper
• mTOR signaling in growth control and disease.

  2012cited by this paper
• Insights into the regulation of protein abundance from proteomic and transcriptomic analyses

  2012cited by this paper
• In vitro inhibition of translation initiation by N,N'-diarylureas--potential anti-cancer agents.

  2012cited by this paper
• Everolimus for Advanced Pancreatic Neuroendocrine Tumors

  2012cited by this paper
• Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.

  2012cited by this paper
• Tumor suppression by small molecule inhibitors of translation initiation

  2012cited by this paper
• Down-regulation of PDCD4 expression is an independent predictor of poor prognosis in human renal cell carcinoma patients

  2012cited by this paper
• Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.

  2012cited by this paper
• Structure-guided design, synthesis, and evaluation of guanine-derived inhibitors of the eIF4E mRNA-cap interaction.

  2012cited by this paper
• Mnk kinases in cytokine signaling and regulation of cytokine responses

  2012cited by this paper
• Aberrations in translational regulation are associated with poor prognosis in hormone receptor-positive breast cancer

  2012cited by this paper
• Translational control in cancer etiology.

  2012cited by this paper
• A unifying model for mTORC1-mediated regulation of mRNA translation

  2012cited by this paper
• Distinct perturbation of the translatome by the antidiabetic drug metformin

  2012cited by this paper
• Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

  2012cited by this paper
• Cap‐Dependent Translation Initiation Factor eIF4E: An Emerging Anticancer Drug Target

  2012cited by this paper
• Regulation of mRNA translation by signaling pathways.

  2012cited by this paper
• Up-regulation of Translation Eukaryotic Initiation Factor 4E in Nucleophosmin 1 Haploinsufficient Cells Results in Changes in CCAAT Enhancer-binding Protein α Activity

  2012cited by this paper
• Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis.

  2012cited by this paper
• Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cells.

  2012cited by this paper
• mTOR inhibitor efficacy is determined by the eIF4E/4E-BP ratio

  2012cited by this paper
• Investigating metformin for cancer prevention and treatment: the end of the beginning.

  2012cited by this paper
• eIF4E/4E-BP ratio predicts the efficacy of mTOR targeted therapies.

  2012cited by this paper
• The hallmarks of cancer

  2012cited by this paper
• The translational landscape of mTOR signalling steers cancer initiation and metastasis

  2012cited by this paper
• Emerging therapeutics targeting mRNA translation.

  2012cited by this paper
• Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

  2012cited by this paper
• Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.

  2011cited by this paper
• A Phase 1 Dose Escalation, Pharmacokinetic, and Pharmacodynamic Evaluation of eIF-4E Antisense Oligonucleotide LY2275796 in Patients with Advanced Cancer

  2011cited by this paper
• Everolimus for advanced pancreatic neuroendocrine tumors.

  2011cited by this paper
• Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

  2011cited by this paper
• Effects of hippuristanol, an inhibitor of eIF4A, on adult T-cell leukemia.

  2011cited by this paper
• Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

  2011cited by this paper
• Resistance to the Translation Initiation Inhibitor Silvestrol is Mediated by ABCB1/P-Glycoprotein Overexpression in Acute Lymphoblastic Leukemia Cells

  2011cited by this paper

• Rapid and sensitive detection of RNA biomarkers using morpholino-functionalized organic electrochemical transistor

  2026cites this paper
• Bridging technical innovation and computational advances in studies of RNA-protein assemblies.

  2026cites this paper
• Inhibitor screening identifies Entecavir as a promising candidate targeting human eIF4E to block cap-dependent translation in cancer: an integrated in silico and in vitro study

  2026cites this paper
• Rewiring of host cell signaling in chikungunya virus infection: a mechanism for pathogenesis and therapeutic approaches

  2026cites this paper
• METTL1-mediated m7G tRNA modification promotes colorectal cancer progression and liver metastasis via translational regulation

  2026cites this paper
• Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine-dependent Tumor Subset Under Metabolic Relationships With CAFs.

  2026cites this paper
• Cytoplasmic FKBP7 reflux controls NFE2L1 levels as an adaptive response to chemotherapy in prostate cancer cells

  2026cites this paper
• The ribosomal landscape in influenza A virus infection: from molecular mechanisms to clinical relevance

  2026cites this paper
• Ligand-Induced Structural Dynamics Drive Allosteric Regulation of Translation Initiation Factor eIF4E

  2026cites this paper
• RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia

  2025cites this paper
• Subtype Characterization of Ovarian Cancer Cell Lines Using Machine Learning and Network Analysis: A Pilot Study

  2025cites this paper
• Hypoxia-mediated regulation of mRNA metabolism: from transcription to stability

  2025influential citation
• Hexavalent chromium promotes malignant transformation via enhanced translation of SUV39H1.

  2025cites this paper
• Eukaryotic translation initiation factor 4F: functional properties and physiological role

  2025cites this paper
• Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic ductal adenocarcinoma.

  2025cites this paper
• Translational control of leukemic metabolism and disease progression.

  2025cites this paper
• The implication of non-AUG-initiated N-terminally extended proteoforms in cancer

  2025cites this paper
• Praja2 controls P-body assembly and translation in glioblastoma by non-proteolytic ubiquitylation of DDX6

  2025cites this paper
• Single-cell and Spatial Omics Reveals Region-Specific Plasticity and Therapeutic Vulnerabilities in Metastatic High-Risk Neuroblastoma

  2025cites this paper
• Discovery of novel hydrazinyl thiazole derivatives as potent anticancer agents by inhibiting eIF4E/eIF4G interactions.

  2025cites this paper
• mTORC1 cooperates with tRNA wobble modification to sustain the protein synthesis machinery

  2025cites this paper
• NOC4L serves as a novel prognostic marker and therapeutic target for lung adenocarcinoma

  2025cites this paper
• FTO degrader impairs ribosome biogenesis and protein translation in acute myeloid leukemia

  2025cites this paper
• The proteostasis network is a therapeutic target in acute myeloid leukemia

  2025cites this paper
• Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

  2025cites this paper
• lncRNAs: the unexpected link between protein synthesis and cancer adaptation

  2025cites this paper
• N7-methylguanosine tRNA modification promotes gastric cancer progression by activating SDHAF4-dependent mitochondrial oxidative phosphorylation.

  2025cites this paper
• Translational regulation of SND1 governs endothelial homeostasis during stress

  2025cites this paper
• Cytotoxic crinane alkaloids of the Amaryllidaceae: in vitro, in vivo and in silico effects, structure–activity relationships and mechanisms of action

  2025cites this paper
• The many ways to inhibit translation by Sorafenib in liver cancer cells

  2025cites this paper
• Ribosome Biogenesis and Function in Cancer: From Mechanisms to Therapy

  2025cites this paper
• RNA Epigenetics in Cancer: Current Knowledge and Therapeutic Implications

  2025cites this paper
• Targeting Eukaryotic Elongation Factor 1A: How Small-Molecule Inhibitors Suppress Tumor Growth via Diverse Pathways

  2025cites this paper
• The intersection between metabolism and translation through a subcellular lens.

  2025cites this paper
• Polysomal profiling coupled to allele-specific proteomics reveals an EIF4H tranSNP allele possessing higher mRNA translation potential

  2025cites this paper
• Chemical Probes for Studying the Eukaryotic Translation Initiation Factor 4E (eIF4E)-Regulated Translatome in Cancer.

  2025cites this paper
• eIF4F-mediated dysregulation of mRNA translation in cancer

  2025cites this paper
• Genetic-informed alternative RNA splicing serves an essential role in carcinogenesis and prognosis of non-small-cell lung cancer

  2025cites this paper
• A Comparison of Conserved Features in the Human Coronavirus Family Shows That Studies of Viruses Less Pathogenic than SARS-CoV-2, Such as HCoV-OC43, Are Good Model Systems for Elucidating Basic Mechanisms of Infection and Replication in Standard Laboratories

  2025cites this paper
• AR and YAP crosstalk: impacts on therapeutic strategies in prostate cancer

  2025cites this paper
• Conditional deep learning model reveals translation elongation determinants during amino acid deprivation

  2025cites this paper
• EEF1AKMT4-eEF1A2 synergistically facilitates the progression of GBC by promoting ribosomal protein output

  2025cites this paper
• PTBP1 and Cancer: From RNA Regulation to Therapeutic Potential

  2025cites this paper
• The nucleocapsid protein of Crimean–Congo hemorrhagic fever virus interacts with eIF4A to promote the translation of viral mRNA in cells

  2025cites this paper
• Pan-cancer analysis identifies tRNA modification enzyme CTU2 as a novel tumor biomarker and its role in immune microenvironment

  2025cites this paper
• 4E-BP1–dependent translation in microglia controls mechanical hypersensitivity in male and female mice

  2025cites this paper
• Peptide–Drug Conjugates as Next-Generation Therapeutics: Exploring the Potential and Clinical Progress

  2025cites this paper
• Programmable translational inhibition by a molecular glue-oligonucleotide conjugate

  2025cites this paper
• SRSF3 is oncogenic in breast but tumor-suppressive in liver by differential regulation of gene expression

  2025influential citation
• Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer

  2024cites this paper
• Canada's contributions to RNA research: past, present and future perspectives.

  2024cites this paper
• The crosstalk between metabolism and translation.

  2024cites this paper
• Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors.

  2024cites this paper
• Auraptene Boosts the Efficacy of the Tamoxifen Metabolites Endoxifen and 4-OH-Tamoxifen in a Chemoresistant ER+ Breast Cancer Model

  2024cites this paper
• Reactive oxygen species driven prodrug-based nanoscale carriers for transformative therapies.

  2024cites this paper
• Identification of a pro-protein synthesis osteosarcoma subtype for predicting prognosis and treatment

  2024cites this paper
• Pharmacologic Inhibition of EIF4A Blocks NRF2 Synthesis to Prevent Osteosarcoma Metastasis

  2024cites this paper
• RIPK1 inhibition mitigates neuroinflammation and rescues depressive-like behaviors in a mouse model of LPS-induced depression

  2024cites this paper
• The Paradox of Ribosomal Insufficiency Coupled with Increased Cancer: Shifting the Perspective from the Cancer Cell to the Microenvironment

  2024cites this paper
• Capivasertib reverses chemotherapy-induced esophageal cancer resistance via inhibiting Akt-associated Mcl-1 upregulation

  2024cites this paper
• The heterogeneity of breast cancer metastasis: a bioinformatics analysis utilizing single-cell RNA sequencing data

  2024cites this paper
• PPM1G dephosphorylates eIF4E in control of mRNA translation and cell proliferation

  2024cites this paper
• 4EBP1-mediated SLC7A11 protein synthesis restrains ferroptosis triggered by MEK inhibitors in advanced ovarian cancer

  2024cites this paper
• EIF4G2 Promotes Hepatocellular Carcinoma Progression via IRES-dependent PLEKHA1 Translation Regulation.

  2024cites this paper
• eIF4F complex dynamics are important for the activation of the integrated stress response

  2024cites this paper
• Advances in Raman spectroscopy for characterising oral cancer and oral potentially malignant disorders

  2024cites this paper
• Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit

  2024cites this paper
• Tumor Antigens beyond the Human Exome

  2024cites this paper
• mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3IBTK-mediated ubiquitination of eIF4A1 in cancer cells

  2024cites this paper
• Molecular interaction and MD-simulations: investigation of Sizofiran as a promising anti-cancer agent targeting eIF4E in colorectal cancer

  2024cites this paper
• Integrating fragment-based screening with targeted protein degradation and genetic rescue to explore eIF4E function

  2024cites this paper
• FBXO32 Stimulates Protein Synthesis to Drive Pancreatic Cancer Progression and Metastasis.

  2024cites this paper
• N-MYC regulates cell survival via eIF4G1 in inv(16) acute myeloid leukemia

  2024cites this paper
• Second-Generation Cap Analogue Prodrugs for Targeting Aberrant Eukaryotic Translation Initiation Factor 4E Activity in Cancer.

  2024cites this paper
• Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects

  2024cites this paper
• Protein translation: biological processes and therapeutic strategies for human diseases

  2024cites this paper
• Mutant U2AF1-induced mis-splicing of mRNA translation genes confers resistance to chemotherapy in acute myeloid leukemia.

  2024cites this paper
• CPEB4 modulates liver cancer progression by translationally regulating hepcidin expression and sensitivity to ferroptosis

  2024cites this paper
• Inhibiting HnRNP L-mediated alternative splicing of EIF4G1 counteracts immune checkpoint blockade resistance in Castration-resistant prostate Cancer

  2024cites this paper
• RNA modification-mediated mRNA translation regulation in liver cancer: mechanisms and clinical perspectives

  2024cites this paper
• METTL3 drives NSCLC metastasis by enhancing CYP19A1 translation and oestrogen synthesis

  2024cites this paper
• RNPS1 stabilizes NAT10 protein to facilitate translation in cancer via tRNA ac4C modification

  2024cites this paper
• Antiaging Strategies and Remedies: A Landscape of Research Progress and Promise

  2024cites this paper
• A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer

  2024influential citation
• Hypusine Signaling Promotes Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension.

  2024cites this paper
• The human eIF4E:4E-BP2 complex structure for studying hyperphosphorylation.

  2024cites this paper
• N6-methyladenosine in 28S rRNA promotes oncogenic mRNA translation and tyrosine catabolism.

  2024cites this paper
• New magnetic iron nanoparticle doped with selenium nanoparticles and the mechanisms of their cytoprotective effect on cortical cells under ischemia-like conditions.

  2024cites this paper
• Metabolism and mRNA translation: a nexus of cancer plasticity.

  2024cites this paper
• Ribosomal rodeo: wrangling translational machinery in gynecologic tumors

  2024cites this paper
• Phase Ib pharmacodynamic study of the MNK inhibitor Tomivosertib (eFT508) combined with paclitaxel in patients with refractory metastatic breast cancer.

  2024cites this paper
• Reciprocal Dynamics of Metabolism and mRNA Translation in Tumor Angiogenesis

  2024cites this paper
• Inhibition of therapy-resistant and metastatic melanoma by targeting the translation initiation complex

  2024cites this paper
• Autophagy markers expression pattern in developing liver of the yotari (dab1-/-) mice and humans.

  2024cites this paper
• Exploiting Translation Machinery for Cancer Therapy: Translation Factors as Promising Targets

  2024cites this paper
• Non-canonical mRNA translation initiation in cell stress and cancer

  2024cites this paper
• Assessment of translation rate in leukemic cells and immune cells of the microenvironment by OPP protein synthesis assay.

  2024cites this paper
• Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways

  2024influential citation
• Therapeutic synthetic and natural materials for immunoengineering.

  2024cites this paper
• FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis.

  2024cites this paper