Prediction of Drug Resistance in M. tuberculosis: Molecular Mechanisms, Tools, and Applications

No abstract is available for this paper.

• Publication year

  2002

• Venue

  IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology

• Publication date

  2002-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1080/15216540212642PMID 12121001
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Heteroresistance in Mycobacterium tuberculosis.

  2001cited by this paper
• Detection of rpoB Mutations inMycobacterium tuberculosis by Biprobe Analysis

  2001cited by this paper
• The Susceptibility of Mycobacterium tuberculosis to Isoniazid and the Arg→Leu Mutation at Codon 463 of katG Are Not Associated

  2001cited by this paper
• Characterization of Isoniazid-Resistant Strains of Mycobacterium tuberculosis on the Basis of Phenotypic Properties and Mutations in katG

  2001cited by this paper
• Novel Mutations in ndh in Isoniazid-Resistant Mycobacterium tuberculosisIsolates

  2001cited by this paper
• When the chips are down

  2001cited by this paper
• Sequence Polymorphism in the rrs Gene ofMycobacterium tuberculosis Is Deeply Rooted within an Evolutionary Clade and Is Not Associated with Streptomycin Resistance

  2001cited by this paper
• Molecular detection of Mycobacterium tuberculosis: impact on patient care.

  2001cited by this paper
• Analysis for a Limited Number of Gene Codons Can Predict Drug Resistance of Mycobacterium tuberculosis in a High-Incidence Community

  2001cited by this paper
• Molecular Genetic Analysis of Nucleotide Polymorphisms Associated with Ethambutol Resistance in Human Isolates ofMycobacterium tuberculosis

  2000cited by this paper
• Classification of drug-resistant tuberculosis in an epidemic area.

  2000cited by this paper
• Genotypic Analysis of Mycobacterium tuberculosis in Two Distinct Populations Using Molecular Beacons: Implications for Rapid Susceptibility Testing

  2000cited by this paper
• Transmission of a multidrug-resistant Mycobacterium tuberculosis strain resembling "strain W" among noninstitutionalized, human immunodeficiency virus-seronegative patients.

  1999cited by this paper
• Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project.

  1999cited by this paper
• Detection of mutations in drug resistance genes of Mycobacterium tuberculosis by a dot-blot hybridization strategy.

  1999cited by this paper
• Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 update.

  1998cited by this paper
• Molecular beacon sequence analysis for detecting drug resistance in Mycobacterium tuberculosis

  1998cited by this paper
• Survey of drug-resistant tuberculosis in Northwestern Russia from 1984 through 1994

  1998cited by this paper
• Comparison of Three Molecular Assays for Rapid Detection of Rifampin Resistance in Mycobacterium tuberculosis

  1998cited by this paper
• Evaluation of a polymerase chain reaction-based universal heteroduplex generator assay for direct detection of rifampin susceptibility of Mycobacterium tuberculosis from sputum specimens.

  1998cited by this paper
• Inhibition of a Mycobacterium tuberculosis β-Ketoacyl ACP synthase by isoniazid

  1998cited by this paper
• Rapid detection of rifampin-resistant Mycobacterium tuberculosis by sequencing and line probe assay.

  1998cited by this paper
• Inhibition of a Mycobacterium tuberculosis beta-ketoacyl ACP synthase by isoniazid.

  1998cited by this paper
• Mutation in pncA is a major mechanism of pyrazinamide resistance in Mycobacterium tuberculosis.

  1997cited by this paper
• Analysis of the oxyR-ahpC region in isoniazid-resistant and -susceptible Mycobacterium tuberculosis complex organisms recovered from diseased humans and animals in diverse localities

  1997cited by this paper
• Genotypic assessment of isoniazid and rifampin resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level

  1997cited by this paper
• Molecular analysis of katG gene mutations in strains of Mycobacterium tuberculosis complex from Africa

  1997cited by this paper
• Use of polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) analysis to detect a point mutation in the catalase-peroxidase gene (katG) ofMycobacterium tuberculosis

  1997cited by this paper
• When the chips are down.

  1997cited by this paper
• Use of polymerase chain reaction single-strand conformation polymorphism (PCR-SSCP) analysis to detect a point mutation in the catalase-peroxidase gene (katG) of Mycobacterium tuberculosis.

  1997cited by this paper
• Transmission of a highly drug-resistant strain (strain W1) of Mycobacterium tuberculosis. Community outbreak and nosocomial transmission via a contaminated bronchoscope.

  1997cited by this paper
• Detection of rifampin resistance in Mycobacterium tuberculosis by use of a rapid, simple, and specific RNA/RNA mismatch assay.

  1997cited by this paper
• Genome and MIC stability in Mycobacterium tuberculosis and indications for continuation of use of isoniazid in multidrug-resistant tuberculosis.

  1997cited by this paper
• Rapid method for testing susceptibility of Mycobacterium tuberculosis by using DNA probes

  1997cited by this paper
• Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination.

  1997cited by this paper
• Evaluation of the INNO-LiPA Rif. TB assay, a reverse hybridization assay for the simultaneous detection of Mycobacterium tuberculosis complex and its resistance to rifampin

  1997cited by this paper
• Nosocomial spread of human immunodeficiency virus-related multidrug-resistant tuberculosis in Buenos Aires.

  1997cited by this paper
• Detection of resistance to isoniazid, rifampin, and streptomycin in clinical isolates of Mycobacterium tuberculosis by molecular methods.

  1997cited by this paper
• Ethambutol resistance in Mycobacterium tuberculosis: critical role of embB mutations

  1997cited by this paper
• A multi-institutional outbreak of highly drug-resistant tuberculosis: epidemiology and clinical outcomes.

  1996cited by this paper
• Origin and interstate spread of a New York City multidrug-resistant Mycobacterium tuberculosis clone family.

  1996cited by this paper
• Differentiation of bacterial 16S rRNA genes and intergenic regions and Mycobacterium tuberculosis katG genes by structure-specific endonuclease cleavage

  1996cited by this paper
• Characterization of the catalase-peroxidase gene (katG) and inhA locus in isoniazid-resistant and -susceptible strains of Mycobacterium tuberculosis by automated DNA sequencing: restricted array of mutations associated with drug resistance.

  1996cited by this paper
• Nosocomial transmission of multidrug-resistant Mycobacterium tuberculosis in Spain.

  1996cited by this paper
• katG mutations in isoniazid-resistant strains of Mycobacterium tuberculosis are not infrequent

  1996cited by this paper
• Nosocomial transmission of multidrug-resistant Mycobacterium tuberculosis in Spain.

  1996cited by this paper
• Molecular mechanisms of multiple drug resistance in clinical isolates of Mycobacterium tuberculosis.

  1995cited by this paper
• Rapid identification of a point mutation of the Mycobacterium tuberculosis catalase-peroxidase (katG) gene associated with isoniazid resistance.

  1995cited by this paper
• Temporal trends and transmission patterns during the emergence of multidrug-resistant tuberculosis in New York City: a molecular epidemiologic assessment.

  1995cited by this paper
• Tuberculosis in health care workers at a hospital with an outbreak of multidrug-resistant Mycobacterium tuberculosis.

  1995cited by this paper
• Direct genotypic detection of Mycobacterium tuberculosis rifampin resistance in clinical specimens by using single-tube heminested PCR

  1995cited by this paper
• Characterization of the katG and inhA genes of isoniazid-resistant clinical isolates of Mycobacterium tuberculosis

  1995cited by this paper
• Drug resistant tuberculosis in sub-Saharan Africa: an estimation of incidence and cost for the year 2000.

  1995cited by this paper
• Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic.

  1995cited by this paper
• Genotypic detection of Mycobacterium tuberculosis rifampin resistance: comparison of single-strand conformation polymorphism and dideoxy fingerprinting

  1995cited by this paper
• Missense mutations in the catalase‐peroxidase gene, katG, are associated with isoniazid resistance in Mycobacterium tuberculosis

  1995cited by this paper
• Characterization by automated DNA sequencing of mutations in the gene (rpoB) encoding the RNA polymerase beta subunit in rifampin-resistant Mycobacterium tuberculosis strains from New York City and Texas

  1994cited by this paper
• Characterization of rifampin-resistance in pathogenic mycobacteria

  1994cited by this paper
• Implications of multidrug resistance for the future of short-course chemotherapy of tuberculosis: a molecular study

  1994cited by this paper
• Cloning and nucleotide sequence of Mycobacterium tuberculosis gyrA and gyrB genes and detection of quinolone resistance mutations

  1994cited by this paper
• Outbreak of multi-drug-resistant tuberculosis in a New York State prison, 1991.

  1994cited by this paper
• Surveillance of resistance to antituberculosis drugs in developing countries.

  1994cited by this paper
• Transmission of multidrug-resistant Mycobacterium tuberculosis among persons with human immunodeficiency virus infection in an urban hospital: epidemiologic and restriction fragment length polymorphism analysis.

  1993cited by this paper
• Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis.

  1993cited by this paper
• Direct, automated detection of rifampin-resistant Mycobacterium tuberculosis by polymerase chain reaction and single-strand conformation polymorphism analysis

  1993cited by this paper
• Hospital outbreak of multidrug-resistant Mycobacterium tuberculosis infections. Factors in transmission to staff and HIV-infected patients.

  1992cited by this paper
• Nosocomial Transmission of Multidrug-resistant Mycobacterium tuberculosis

  1992cited by this paper
• Tuberculosis: Commentary on a Reemergent Killer

  1992cited by this paper
• An Outbreak of Tuberculosis Caused by Multiple-Drug-resistant Tubercle Bacilli among Patients with HIV Infection

  1992cited by this paper
• An outbreak of multidrug-resistant tuberculosis among hospitalized patients with the acquired immunodeficiency syndrome.

  1992cited by this paper
• Tuberculosis: a global overview of the situation today.

  1992cited by this paper
• Inter-bottle transfer of mycobacteria by the BACTEC 460.

  1989cited by this paper
• Drug susceptibility testing in tuberculosis: a comparison of the proportion methods using Lowenstein-Jensen, Middlebrook 7H10 and 7H11 agar media and a radiometric method.

  1989cited by this paper
• Interlaboratory drug susceptibility testing of Mycobacterium tuberculosis by a radiometric procedure and two conventional methods

  1985cited by this paper
• Evaluation of the BACTEC radiometric method for detection of 1% resistant populations of Mycobacterium tuberculosis

  1985cited by this paper
• Rapid drug-susceptibility testing of Mycobacterium tuberculosis.

  1981cited by this paper

• Mutation Characteristics of inhA and katG Genes in Isoniazid-Resistant Mycobacterium Tuberculosis Patients in Xinjiang

  2024cites this paper
• Structural and Dynamic Insights into the W68L, L85P, and T87A Mutations of Mycobacterium tuberculosis Inducing Resistance to Pyrazinamide

  2022cites this paper
• Antibiotic heteroresistance in Mycobacterium tuberculosis isolates: a systematic review and meta-analysis

  2021cites this paper
• A Review of Phenotypic and Genotypic Methods for Detection of Drug Resistance in Mycobacterium tuberculosis

  2020cites this paper
• Conventional and molecular determination of drug resistance in Mycobacterium tuberculosis and Mycobacterium bovis isolates in cattle.

  2019cites this paper
• Detection of resistant strains of tubercle bacilli by gene mutation hybridization

  2019cites this paper
• Molecular detection of Isoniazid, Rifampin and Ethambutol resistance to M. tuberculosis and M. bovis in multidrug resistant tuberculosis (MDR-TB) patients in Pakistan.

  2017cites this paper
• Sequence analysis of the rifampicin resistance determining region (RRDR) of rpoB gene in multidrug resistance confirmed and newly diagnosed tuberculosis patients of Punjab, Pakistan

  2017cites this paper
• Multidrug Resistance in Tuberculosis: An Overview

  2017cites this paper
• Genotypic, Phenotypic and Clinical Validation of GeneXpert in Extra-Pulmonary and Pulmonary Tuberculosis in India

  2016cites this paper
• Gene mutations in Mycobacterium tuberculosis: multidrug-resistant TB as an emerging global public health crisis.

  2015cites this paper
• Engineering More Stable, Selectable Marker-Free Autoluminescent Mycobacteria by One Step

  2015cites this paper
• Rifoligotyping assay: an alternative method for rapid detection of rifampicin resistance in Mycobacterium tuberculosis isolates from Morocco

  2014cites this paper
• Transmission of Tuberculosis and its Prevention

  2014cites this paper
• Molecular detection of rifampicin resistance in multidrug-resistant Mycobacterium tuberculosis strains from North-Eastern Romania

  2013influential citation
• Rapid identification of extensively and extremely drug resistant tuberculosis from multidrug resistant strains; using PCR-RFLP and PCR-SSCP

  2012cites this paper
• Detection of Mycobacterium tuberculosis and Drug Resistance: Opportunies and Challenges in Morocco

  2012cites this paper
• Mycobacterium tuberculosis mutants with multidrug resistance: History of origin, genetic and molecular mechanisms of resistance, and emerging challenges

  2012cites this paper
• Drug-Resistance in Mycobacterium Tuberculosis: Molecular Basis and Genotypic Detection

  2011cites this paper
• Tuberculosis drug resistance testing by molecular methods: opportunities and challenges in resource limited settings.

  2011cites this paper
• The plant alkaloid piperine as a potential inhibitor of ethidium bromide efflux in Mycobacterium smegmatis.

  2011cites this paper
• Detection of resistance-associated mutations in Mycobacterium tuberculosis isolates in Cameroon using a dot-blot hybridisation technique

  2011cites this paper
• Drug susceptibility test of Mycobacterium tuberculosis by nitrate reductase assay.

  2009cites this paper
• Analysis of isoniazid, streptomycin and ethambutol resistance in Mycobacterium tuberculosis isolates from Morocco.

  2009cites this paper
• A Balancing Act: Efflux/Influx in Mycobacterial Drug Resistance

  2009cites this paper
• Resistance to first line anti-TB drugs by gene mutation and gene modulation

  2009cites this paper
• Drug susceptibility testing using molecular techniques can enhance tuberculosis diagnosis.

  2008cites this paper
• Molecular analysis of multidrug resistantMycobacterium tuberculosis isolates from Morocco

  2008cites this paper
• Understanding the mechanisms of drug resistance in enhancing rapid molecular detection of drug resistance in Mycobacterium tuberculosis

  2007influential citation
• Ethambutol resistance testing by mutation detection.

  2006cites this paper
• Drug resistance in Mycobacterium tuberculosis.

  2006influential citation
• Rapid assessment of drug susceptibility and mutation to resistance in mycobacterium tuberculosis Beijing type

  2006cites this paper
• Evaluation of the rpoB macroarray assay to detect rifampin resistance in Mycobacterium tuberculosis in Beijing, China

  2006cites this paper
• Antimicrobial resistance in tuberculosis: an international perspective

  2006cites this paper
• Risk factors associated with isoniazid resistance in tuberculosis

  2005cites this paper
• Mutational and expression analysis of tbnat and its response to isoniazid.

  2005cites this paper
• Computer prediction of drug resistance mutations in proteins.

  2005cites this paper
• Detection by Denaturing Gradient Gel Electrophoresis of pncA Mutations Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates from the United States-Mexico Border Region

  2005cites this paper
• Simultaneous detection of isoniazid, rifampin, and ethambutol resistance of Mycobacterium tuberculosis by a single multiplex allele-specific polymerase chain reaction (PCR) assay.

  2005cites this paper
• Detection of rpoB Mutations Associated with Rifampin Resistance in Mycobacterium tuberculosis Using Denaturing Gradient Gel Electrophoresis

  2005cites this paper
• Rv2686c-Rv2687c-Rv2688c, an ABC Fluoroquinolone Efflux Pump in Mycobacterium tuberculosis

  2004cites this paper
• Genome variation in Mycobacterium tuberculosis

  2004cites this paper
• an ABC Fluoroquinolone Efflux Pump in Mycobacterium tuberculosis

  2004cites this paper
• Effect of rpoB Mutations Conferring Rifampin Resistance on Fitness of Mycobacterium tuberculosis

  2004cites this paper
• Accurate mapping of mutations of pyrazinamide-resistant Mycobacterium tuberculosis strains with a scanning-frame oligonucleotide microarray.

  2004cites this paper
• The Molecular Epidemiology of MDR-TB

  2004cites this paper
• Identification of MDR-TB Beijing/W and other Mycobacterium tuberculosis genotypes in Nairobi, Kenya.

  2004cites this paper
• Multicenter evaluation of reverse line blot assay for detection of drug resistance in Mycobacterium tuberculosis clinical isolates.

  2004cites this paper
• PCR-Based Methodology for Detecting Multidrug-Resistant Strains of Mycobacterium tuberculosis Beijing Family Circulating in Russia

  2003cites this paper
• Allele-Specific rpoB PCR Assays for Detection of Rifampin-Resistant Mycobacterium tuberculosis in Sputum Smears

  2003cites this paper