Intravenous lipid emulsion for treatment of local anaesthetic and tricyclic antidepressant toxicity

9

• Publication year

  2016

• Venue

  Unknown venue

• Publication date

  2016-03-19

• Fields of study

  Medicine, Chemistry

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• What are the adverse effects associated with the combined use of intravenous lipid emulsion and extracorporeal membrane oxygenation in the poisoned patient?

  2015cited by this paper
• Parenteral emulsions and liposomes to treat drug overdose.

  2015influential reference
• Hemodynamic changes with two lipid emulsions for treatment of bupivacaine toxicity in swines.

  2015cited by this paper
• Fatalities and hospitalisations due to acute poisoning among New Zealand adults

  2014cited by this paper
• Anaphylactic shock with intravenous 20% lipid emulsion in a young patient: Should we ask about soybean allergy beforehand?

  2014cited by this paper
• Continuous renal replacement therapy circuit failure after antidote administration

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• Lipid emulsion use precluding renal replacement therapy.

  2014cited by this paper
• Lipid resuscitation in pediatric patients – need for caution?

  2014cited by this paper
• Intraosseous Lipid Emulsion: An Effective Alternative to IV Delivery in Emergency Situations

  2014cited by this paper
• Prolonged Use of Intravenous Lipid Emulsion in a Severe Tricyclic Antidepressant Overdose

  2014cited by this paper
• Effect of long‐chain triglyceride lipid emulsion on bupivacaine‐induced changes in electrophysiological parameters of rabbit Purkinje cells

  2014cited by this paper
• Resuscitation with Lipid Emulsion: Dose-dependent Recovery from Cardiac Pharmacotoxicity Requires a Cardiotonic Effect

  2014cited by this paper
• Pretreatment with intravenous lipid emulsion reduces mortality from cocaine toxicity in a rat model.

  2014cited by this paper
• Measurement of the efficacy of 2% lipid in reversing bupivacaine- induced asystole in isolated rat hearts

  2014cited by this paper
• Hypersensitivity Reactions to Intravenous Lipid Emulsion in Swine: Relevance for Lipid Resuscitation Studies

  2014cited by this paper
• Should we consider the infusion of lipid emulsion in the resuscitation of poisoned patients?

  2014cited by this paper
• Lipid rescue: does the sink hold water? And other controversies.

  2014cited by this paper
• Other Complications Following Lipid Emulsion Therapy

  2014cited by this paper
• Lipid emulsion pretreatment has different effects on mepivacaine and bupivacaine cardiac toxicity in an isolated rat heart model.

  2014cited by this paper
• Fat overload syndrome after the rapid infusion of SMOFlipid emulsion.

  2014cited by this paper
• Successful Resuscitation With Intralipid After Marcaine Overdose.

  2014cited by this paper
• Resuscitation with lipid, epinephrine, or both in levobupivacaine-induced cardiac toxicity in newborn piglets.

  2014cited by this paper
• Complications Following Antidotal Use of Intravenous Lipid Emulsion Therapy

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• Drug Overdose Surveillance Using Hospital Discharge Data

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• Lipid Rescue Reverses the Bupivacaine-induced Block of the Fast Na+ Current (INa) in Cardiomyocytes of the Rat Left Ventricle

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• Intralipid emulsion treatment as an antidote in lipophilic drug intoxications.

  2014cited by this paper
• Management of near fatal mixed tricyclic antidepressant and selective serotonin reuptake inhibitor overdose with Intralipid®20% emulsion.

  2013cited by this paper
• Liposomal drug delivery systems: from concept to clinical applications.

  2013cited by this paper
• Rapid Cardiotonic Effects of Lipid Emulsion Infusion*

  2013cited by this paper
• Effect of lipid emulsion on the central nervous system and cardiac toxicity of bupivacaine and levobupivacaine in awake rats

  2013cited by this paper
• Mitochondrial Respiration Medium - MiR06

  2013cited by this paper
• Suspected tricyclic antidepressant overdose successfully treated with lipids.

  2013cited by this paper
• Usefulness of intravenous lipid emulsion for cardiac toxicity from cocaine overdose.

  2013cited by this paper
• Use of intravenous lipid emulsion in the resuscitation of a patient with cardiovascular collapse after a severe overdose of quetiapine

  2013cited by this paper
• Comparison of intravenous lipid emulsion, bicarbonate, and tailored liposomes in rabbit clomipramine toxicity.

  2013cited by this paper
• Lipid emulsion-mediated reversal of toxic-dose aminoamide local anesthetic-induced vasodilation in isolated rat aorta

  2013cited by this paper
• Lipid Emulsions Enhance the Norepinephrine-Mediated Reversal of Local Anesthetic-Induced Vasodilation at Toxic Doses

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• Intravenous lipid emulsion in wide complex arrhythmia with alternating bundle branch block pattern from cocaine overdose.

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• Ultrasound Guidance Reduces the Risk of Local Anesthetic Systemic Toxicity Following Peripheral Nerve Blockade

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• The Effect of Lipid Emulsion on Pharmacokinetics and Tissue Distribution of Bupivacaine in Rats

  2013influential reference
• An assessment of the in vivo effects of intravenous lipid emulsion on blood drug concentration and haemodynamics following oro-gastric amitriptyline overdose

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• Prolonged lipemia and pancreatitis due to extended infusion of lipid emulsion in bupropion overdose

  2013cited by this paper
• Intralipid as antidote for tricyclic antidepressants and SSRIs: a case report.

  2012cited by this paper
• "Lipid rescue" for tricyclic antidepressant cardiotoxicity.

  2012cited by this paper
• [Reversal of neurologic symptoms related to lidocaine toxicity with a lipid emulsion administration].

  2012cited by this paper
• Hemodynamic changes in lipid emulsion therapy (SMOFlipid) for bupivacaine toxicity in swines.

  2012cited by this paper
• Resuscitation strategies from bupivacaine‐induced cardiac arrest

  2012cited by this paper
• The Comparative Effects of Lipid, Epinephrine, and Their Combination in the Reversal of Bupivacaine-Induced Asystole in the Isolated Rat Heart

  2012cited by this paper
• High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle.

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• Comparison of lipid sinks in sequestering common intoxicating drugs.

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• Convulsions after normal dose of lidocaine: a probable drug interaction.

  2012cited by this paper
• No antidotal effect of intravenous lipid emulsion in experimental amitriptyline intoxication despite significant entrapment of amitriptyline.

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• Swine as Models in Biomedical Research and Toxicology Testing

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• Voltage‐gated sodium channels at 60: structure, function and pathophysiology

  2012cited by this paper
• Further support for the early administration of lipid emulsion in the treatment of ropivacaine-induced central nervous system toxicity

  2012cited by this paper
• Effect of intravenous lipid emulsion on bupivacaine plasma concentration in humans

  2012cited by this paper
• Fatty-acid oxidation and calcium homeostasis are involved in the rescue of bupivacaine-induced cardiotoxicity by lipid emulsion in rats*

  2012influential reference
• Pig in a Poke: Species Specificity in Modeling Lipid Resuscitation

  2012cited by this paper
• Association of sustained cardiovascular recovery with epinephrine in the delayed lipid-based resuscitation from cardiac arrest induced by bupivacaine overdose in rats.

  2012cited by this paper
• In vitro and in vivo entrapment of bupivacaine by lipid dispersions.

  2012cited by this paper
• Analytical interferences resulting from intravenous lipid emulsion

  2012cited by this paper
• Case report: successful lipid resuscitation in multi-drug overdose with predominant tricyclic antidepressant toxidrome

  2012cited by this paper
• Lipid therapy with two agents in ropivacaine-induced toxicity: experimental study in Swine.

  2012cited by this paper
• Substances Used in Completed Suicide by Overdose in Toronto: An Observational Study of Coroner's Data

  2012cited by this paper
• IgE-mediated allergy to local anaesthetics: separating fact from perception: a UK perspective.

  2012cited by this paper
• Use of Intravenous Lipid Emulsion to Reverse Central Nervous System Toxicity of an Iatrogenic Local Anesthetic Overdose in a Patient on Peritoneal Dialysis

  2012cited by this paper
• Lipid therapy for the treatment of a refractory amitriptyline overdose.

  2012cited by this paper
• Local anesthetic-induced complete atrioventricular block during awake craniotomy.

  2012cited by this paper
• American Society of Regional Anesthesia and Pain Medicine Checklist for Managing Local Anesthetic Systemic Toxicity: 2012 Version

  2011cited by this paper
• Prolongation of Epidural Analgesia Using Solid Lipid Nanoparticles as Drug Carrier for Lidocaine

  2011cited by this paper
• Guidelines in Emergency Medicine Network (GEMNet): guideline for the management of tricyclic antidepressant overdose

  2011cited by this paper
• Fatty acids antagonize bupivacaine - induced INa blockade

  2011cited by this paper
• Intractable cardiac arrest due to lidocaine toxicity successfully resuscitated with lipid emulsion*

  2011cited by this paper
• Successful treatment of ropivacaine-induced central nervous system toxicity by use of lipid emulsion: effect on total and unbound plasma fractions

  2011influential reference
• Successful reversal of life threatening cardiac effect following dosulepin overdose using intravenous lipid emulsion

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• Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart.

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• Combined lipid emulsion and ACLS resuscitation following bupivacaine- and hypoxia-induced cardiovascular collapse in unanesthetized swine.

  2011cited by this paper
• Comparison of epinephrine vs lipid rescue to treat severe local anesthetic toxicity – an experimental study in piglets

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• Treatment of cocaine overdose with lipid emulsion

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• Neurometabolic correlates of depression and disability in episodic cluster headache

  2010influential reference
• Lipid emulsions in the treatment of acute poisoning: a systematic review of human and animal studies

  2010cited by this paper
• Prevention of parenteral nutrition-associated liver disease: role of ω-3 fish oil

  2010cited by this paper
• Lipid infusion rescue for bupivacaine-induced cardiac arrest after axillary block.

  2010cited by this paper
• Parenteral lipids impair pneumococcal elimination by human neutrophils

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• Successful resuscitation after inadvertent intravenous injection of bupivacaine in an adolescent

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• Lipid Emulsion Reverses Bupivacaine-induced Asystole in Isolated Rat Hearts: Concentration-Response and Time-Response Relationships

  2010cited by this paper
• Lipid rescue for bupivacaine toxicity during cardiovascular procedures

  2010cited by this paper
• Interaction of a commercial lipid dispersion and local anesthetics in human plasma: implications for drug trapping by “lipid-sinks”

  2010cited by this paper
• Successful resuscitation of bupivacaine‐induced cardiotoxicity in a neonate

  2010cited by this paper
• Successful use of intravenous fat emulsion in severe poisoning following ingestion of lipid soluble drugs [Abstract]

  2010cited by this paper
• Use of lipid emulsions for treatment of local anesthetic toxicity: a case report.

  2010cited by this paper
• Lipid resuscitation in a carnitine deficient child following intravascular migration of an epidural catheter *

  2010cited by this paper
• Lipid Emulsion Improves Recovery from Bupivacaine-Induced Cardiac Arrest, but Not from Ropivacaine- or Mepivacaine-Induced Cardiac Arrest

  2009cited by this paper
• Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

  2009cited by this paper
• Correlation of plasma and peritoneal diasylate clomipramine concentration with hemodynamic recovery after intralipid infusion in rabbits.

  2009cited by this paper
• The successful use of intralipid for treatment of local anesthetic-induced central nervous system toxicity: Some considerations for administration of intralipid in an emergency.

  2009cited by this paper
• Recurrence of cardiotoxicity after lipid rescue from bupivacaine-induced cardiac arrest.

  2009cited by this paper
• Failure of lipid emulsion to reverse neurotoxicity after an ultrasound-guided axillary block with ropivacaine and mepivacaine

  2009cited by this paper

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