Severe expression of corpus gastritis is characteristic in gastric cancer patients infected with Helicobacter pylori.

Stephan Miehlke,A. Hackelsberger,A. Meining,R. Hatz,N. Lehn,P. Malfertheiner,M. Stolte,E. Bayerdörffer

Published 1998 in British Journal of Cancer

ABSTRACT

In 50 Helicobacter pylori-infected gastric carcinoma patients the corpus gastritis was significantly higher than in matched H. pylori-positive control subjects (P < 0.01). Atrophy and intestinal metaplasia (IM) occurred significantly more often in the antrum of carcinoma patients (P < 0.01). The odds ratio for gastric carcinoma was 8.85 for high-grade corpus gastritis and 8.04 when atrophy in the antrum was present.

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