Some critical determinants of the behaviour of rats in the elevated plus-maze.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Behavioural Processes

• Publication date

  1993-04-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/0376-6357(93)90026-NPMID 24897695
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• One-trial tolerance to the anxiolytic effects of chlordiazepoxide in the plus-maze

  2005cited by this paper
• Effects of diazepam on behavioural and antinociceptive responses to the elevated plus-maze in male mice depend upon treatment regimen and prior maze experience

  2005cited by this paper
• Antianxiety effect of cannabidiol in the elevated plus-maze

  2005cited by this paper
• Antinociceptive effects of elevated plus-maze exposure: influence of opiate receptor manipulations

  2005cited by this paper
• Effects of DN-2327, a new anxiolytic, diazepam and buspirone on exploratory activity of the rat in an elevated plus-maze

  2005cited by this paper
• Lack of effects of 5HT3 receptor antagonists in the social interaction and elevated plus-maze tests of anxiety in the rat

  2004cited by this paper
• An evaluation of the elevated plus-maze test using the novel anxiolytic buspirone

  2004cited by this paper
• Effects in the X-maze anxiety model of agents acting at 5-HT1 and 5-HT2 receptors

  2004cited by this paper
• The use of a plus-maze to measure anxiety in the mouse

  2004cited by this paper
• Resistance of baseline activity in the elevated pius‐maze to exogenous influences

  1992influential reference
• Effects of 8‐OH-DPAT and buspirone in a passive avoidance test and in the elevated plus‐maze test in rats

  1991cited by this paper
• Characterization of MDL 73005EF as a 5‐HT1A selective ligand and its effects in animal models of anxiety: comparison with buspirone, 8‐OH‐DPAT and diazepam

  1990influential reference
• Modulation of baseline behavior in rats by putative serotonergic agents in three ethoexperimental paradigms.

  1990cited by this paper
• Ethologically-based animal models of anxiety disorders.

  1990cited by this paper
• The effects of 5-HT1B characterizing agents in the mouse elevated plus-maze.

  1990cited by this paper
• Intra-hippocampal buspirone in animal models of anxiety.

  1989cited by this paper
• Effects of floor surface and environmental illumination on exploratory activity in the elevated plus-maze.

  1989cited by this paper
• Anticonflict and rotarod impairing effects of alprazolam and diazepam in rat after acute and subchronic administration.

  1989cited by this paper
• Effects of 5-HT1A receptor agonists and NMDA receptor antagonists in the social interaction test and the elevated plus maze.

  1989cited by this paper
• Sodium valproate and chlordiazepoxide in the elevated plus-maze test of anxiety in the rat.

  1988cited by this paper
• Evidence for simultaneous anxiolytic and aversive effects several hours after administration of sodium phenobarbitone to the rat.

  1988cited by this paper
• Profiles of the antipanic compounds, triazolobenzodiazepines and phenelzine, in two animal tests of anxiety.

  1988cited by this paper
• Selective agonists and antagonists for 5‐hydroxytryptamine receptor subtypes, and interactions with yohimbine and FG 7142 using the elevated plus‐maze test in the rat

  1987cited by this paper
• Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.

  1986cited by this paper
• Anxiolytic and anxiogenic drug effects in a novel test of anxiety: are exploratory models of anxiety in rodents valid?

  1986cited by this paper
• Animal models for the study of anti-anxiety agents: a review.

  1985cited by this paper
• Exploratory behavior models of anxiety in mice.

  1985cited by this paper
• Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat.

  1985influential reference
• The effects of triazolobenzodiazepines in two animal tests of anxiety and in the holeboard

  1985cited by this paper
• What can be learned from the effects of benzodiazepines on exploratory behavior?

  1985cited by this paper
• Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of ‘fear’-motivated behaviour

  1984cited by this paper
• The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs.

  1980cited by this paper
• Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines.

  1980cited by this paper
• The relation between fear induced by novel stimulation and exploratory behavior.

  1955cited by this paper
• The relation between fear induced by novel stimulation and exploratory drive.

  1955cited by this paper

• Adolescent high-fructose corn syrup consumption contributes to protracted dysregulation of adult accumbal neuroinflammation and affective behaviors.

  2025cites this paper
• Acute Stress Affects the Relaxin/Insulin-Like Family Peptide Receptor 3 mRNA Expression in Brain of Pubertal Male Wistar Rats.

  2024cites this paper
• An Amygdalar Oscillator Coordinates Cellular and Behavioral Rhythms

  2024cites this paper
• Adaptogenic action of diosgenin againsts chronic unpredictable mild stress-induced neuroimmune dysfunction of HPA axis reverses psychiatric behavior in mice

  2024cites this paper
• Higher exploratory and vigilant behaviors related to higher central dopaminergic activities of Formosan wood mice (Apodemus semotus) in light-dark exploration tests.

  2024cites this paper
• Kamishoyosan and Kamikihito protect against decreased KCC2 expression induced by the P. gingivalis lipopolysaccharide treatment in PC-12 cells and improve behavioral abnormalities in male mice

  2023cites this paper
• Behavioral comparison of the C57BL/6 inbred mouse strain and their CB6F1 siblings.

  2023cites this paper
• Forty-kHz ultrasonic vocalizations of rat pups predict adult behavior in the elevated plus-maze behavior but not the effect of cocaine on 50-kHz ultrasonic vocalizations.

  2023cites this paper
• Effects of test experience, closed-arm wall color, and illumination level on behavior and plasma corticosterone response in an elevated plus maze in male C57BL/6J mice: a challenge against conventional interpretation of the test

  2021cites this paper
• Combining Animal Welfare With Experimental Rigor to Improve Reproducibility in Behavioral Neuroscience

  2021cites this paper
• The Anxiogenic Effects of Caffeine Do Not Potentiate Nicotine Withdrawal in an Elevated Plus Maze Model of Anxiety

  2020cites this paper
• Neural Markers of Vulnerability to Anxiety Outcomes after Traumatic Brain Injury

  2020cites this paper
• Comparative Effects of Imipramine and Chlorpromazine on Neurobehavioural Parameters in Stressed Mice

  2019influential citation
• Diazepam Reduces Escape and Increases Closed-Arms Exploration in Gerbils After 5 min in the Elevated Plus-Maze

  2019cites this paper
• Long-Term Effects of Traumatic Brain Injury on Anxiety-Like Behaviors in Mice: Behavioral and Neural Correlates

  2019cites this paper
• GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior

  2019cites this paper
• Receptor-Receptor Interactions in the Central Nervous System

  2018cites this paper
• The swimming plus-maze test: a novel high-throughput model for assessment of anxiety-related behaviour in larval zebrafish. (Danio rerio)

  2018cites this paper
• Recording Field Potentials and Synaptic Plasticity From Freely Behaving Rodents

  2018cites this paper
• Redução dos comportamentos relacionados à ansiedade em ratos submetidos a 4 semanas de treinamento resistido diário

  2018cites this paper
• Repeated elevated plus maze trials as a measure for tracking within-subjects behavioral performance in rats (Rattus norvegicus)

  2018cites this paper
• The swimming plus-maze test: a novel high-throughput model for assessment of anxiety-related behaviour in larval and juvenile zebrafish (Danio rerio)

  2018cites this paper
• Behavioral Methods to Study the Impact of Receptor–Receptor Interactions in Fear and Anxiety

  2018cites this paper
• The expression of amphetamine sensitization is dissociable from anxiety and aversive memory: Effect of an acute injection of amphetamine.

  2017cites this paper
• Sex Differences in the Anxiety Effects of Cannabinoids

  2017influential citation
• Slope climbing challenges, fear of heights, anxiety and time of the day

  2017cites this paper
• κ Opioid receptor activation in different brain regions differentially modulates anxiety-related behaviors in mice.

  2016cites this paper
• Gerbils exhibit stable open-arms exploration across repeated testing on the elevated plus-maze.

  2016cites this paper
• Behavioral Phenotype of Fmr1 Knock-Out Mice during Active Phase in an Altered Light/Dark Cycle123

  2016cites this paper
• THE EFFECTS OF OPEN FIELD EXPOSURE ON THE ANXIETY AND LOCOMOTIVE BEHAVIOR OF ADULT MALE WISTAR RATS IN ELEVATED PLUS MAZE

  2016cites this paper
• Short term, low dose fluoxetine blocks estrous cycle-linked changes in responsiveness to diazepam in female rats

  2016cites this paper
• Behavior in the elevated plus maze is differentially affected by testing conditions in rats under and over three weeks of age

  2015cites this paper
• Androgen insensitive male rats display increased anxiety-like behavior on the elevated plus maze.

  2014cites this paper
• EFEITO ANTINATRIOREXIGÊNICO E ANSIOLÍTICO DA ADMINISTRAÇÃO INTRACEREBRAL DE CARVACROL EM RATOS: INFLUÊNCIA DAS VIAS SEROTONINÉRGICAS, ADRENÉRGICAS E POSSÍVEIS ÁREAS CEREBRAIS ENVOLVIDAS

  2014cites this paper
• Um estudo do comportamento social de duplas de ratos (Rattus norvegicus)

  2014cites this paper
• Investigation of dose-related effects of carnosine on anxiety with sympathetic skin response and T-maze.

  2014cites this paper
• The free-exploratory paradigm as a model of trait anxiety in female rats: test-retest reliability.

  2014cites this paper
• Elevated Plus Maze Test to Assess Anxiety-like Behavior in the Mouse

  2014cites this paper
• Influence of procedural variables on rat inhibitory avoidance and escape behaviors generated by the elevated T-maze.

  2014cites this paper
• H1 but not H2 histamine antagonist receptors mediate anxiety-related behaviors and emotional memory deficit in mice subjected to elevated plus-maze testing

  2013cites this paper
• EFECTOS DEL BLOQUEO DEL SISTEMA NERVIOSO AUTONOMO PERIFERICO SOBRE LA MEMORIA EMOCIONAL Y LA ANSIEDAD EVALUADAS EN EL LABERINTO EN CRUZ ELEVADO

  2013cites this paper
• EFECTO DE DIFERENTES NIVELES DE LUZ EN LAS CAJAS VIVERO SOBRE EL COMPORTAMIENTO EN EL LABERINTO EN CRUZ ELEVADO DE RATAS WISTAR TRATADAS CON MIDAZOLAM

  2012cites this paper
• 1-histamine receptors in the amygdala are involved in emotional memory but o not mediate anxiety-related behaviors in mice submitted to EPM testing

  2012cites this paper
• The endocannabinoid transport inhibitor AM404 differentially modulates recognition memory in rats depending on environmental aversiveness

  2012cites this paper
• Neural networks in a mouse model of amyloid pathology

  2012cites this paper
• Behavioral Analysis of the Stress-reducing Effects of Coffee Volatiles in Mice

  2011cites this paper
• The effects of pentylenetetrazol, chlordiazepoxide and caffeine in rats tested in the elevated plus-maze depend on the experimental illumination.

  2011cites this paper
• Cellular correlates of anxiety in CA1 hippocampal pyramidal cells of 5-HT1A receptor knockout mice

  2011cites this paper
• Inhibition of fatty acid amide hydrolase modulates anxiety-like behavior in PCP-treated rats.

  2011cites this paper
• A combined study of behavior and Fos expression in limbic structures after re-testing Wistar rats in the elevated plus-maze.

  2010cites this paper
• Some Guidelines for Defining Personality Differences in Rats

  2009cites this paper
• Individual differences in the sensitivity to serotonergic drugs: a pharmacobehavioural approach using rats selected on the basis of their response to novelty

  2009cites this paper
• Modelado del Comportamiento de Ratas en Laberinto en Cruz Elevado Basado en Redes Neuronales Artificiales

  2009influential citation
• Free versus forced exposure to an elevated plus-maze: evidence for new behavioral interpretations during test and retest

  2009cites this paper
• The free-exploratory paradigm as a model of trait anxiety in rats: test-retest reliability.

  2009cites this paper
• Is the anxiolytic-like effect of acute 8-0H-DPAT mediated by 5-HT 1A receptors?

  2008cites this paper
• Preference for the light compartment of a light/dark cage does not affect rat exploratory behavior in the elevated plus-maze

  2008cites this paper
• Behavioral and Brain Functions

  2008cites this paper
• Increased fear‐ and stress‐related anxiety‐like behavior in mice lacking tuberoinfundibular peptide of 39 residues

  2008cites this paper
• Artículos Originales Impacto del confinamiento sobre crisis convulsivas y memoria emocional en ratas Wistar

  2008cites this paper
• Análisis comportamental de ratas expuestas al laberinto en cruz elevado bajo dos horarios de alimentación

  2008cites this paper
• Activity of the medial prefrontal cortex and amygdala underlies one-trial tolerance of rats in the elevated plus-maze.

  2008cites this paper
• Thermal stress decreases general motor activity of rats in the elevated plus-maze but does not alter aversion to the open arms.

  2007cites this paper
• Distinct ventral and dorsal hippocampus AP5 anxiolytic effects revealed in the elevated plus-maze task in rats.

  2007cites this paper
• An approach to evaluate the ability of rats to discriminate different levels of illumination in the plus maze test: effects of scopolamine.

  2007cites this paper
• Effects of under- and overcrowding on exploratory behavior in the elevated plus-maze.

  2007cites this paper
• Developmental differences in acute ethanol withdrawal in adolescent and adult rats.

  2007cites this paper
• Anxiolytic-like effects of (O-methyl)-N-2,6-dihydroxybenzoyl-tyramine (riparin III) from Aniba riparia (Nees) Mez (Lauraceae) in mice.

  2006cites this paper
• Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis.

  2006cites this paper
• O papel da visão na aversão aos espaços abertos no labirinto em cruz elevado

  2006cites this paper
• Retrosplenial cortex lesions impair acquisition of active avoidance while sparing fear-based emotional memory.

  2006cites this paper
• Expressão da proteína Fos em cérebro de ratos expostos ao labirinto em cruz elevado na presença e ausência de iluminação

  2006cites this paper
• Models of anxiety: responses of mice to novelty and open spaces in a 3D maze.

  2006cites this paper
• Factor analysis of elevated plus-maze behavior in adolescent and adult rats.

  2006cites this paper
• Light/dark cycle manipulation influences mice behaviour in the elevated plus maze.

  2006cites this paper
• Effects of the cannabinoid CB1 receptor antagonist rimonabant in models of emotional reactivity in rodents.

  2005cites this paper
• Facteurs de variabilité de l'effet de substances anxiolytiques sur le labyrinthe en croix surélevé chez la Souris

  2005cites this paper
• Age-related qualitative shift in emotional behaviour: paradoxical findings after re-exposure of rats in the elevated-plus maze.

  2005cites this paper
• Use of the elevated plus-maze test with opaque or transparent walls in the detection of mouse strain differences and the anxiolytic effects of diazepam

  2005influential citation
• The gradient of luminosity between open/enclosed arms, and not the absolute level of Lux, predicts the behaviour of rats in the plus maze.

  2005cites this paper
• [Evaluation of anxiety-related behavior in elevated plus-maze test and its applications].

  2005cites this paper
• Effect of different illumination levels on rat behavior in the elevated plus-maze.

  2005cites this paper
• Papel da luminosidade do biotério no comportamento do rato no labirinto em cruz elevado

  2005cites this paper
• Animal models of anxiety.

  2005cites this paper
• Ethological and temporal analyses of anxiety-like behavior: the elevated plus-maze model 20 years on.

  2005influential citation
• Role of learning of open arm avoidance in the phenomenon of one-trial tolerance to the anxiolytic effect of chlordiazepoxide in mice.

  2005cites this paper
• Bidirectional effects of benzodiazepine binding site ligands in the elevated plus-maze: differential antagonism by flumazenil and beta-CCt.

  2004cites this paper
• Differential roles for neuropeptide Y Y1 and Y5 receptors in anxiety and sedation

  2004cites this paper
• Bidirectional effects of benzodiazepine binding site ligands in the elevated plus-maze: differential antagonism by flumazenil and β-CCt

  2004cites this paper
• Context‐dependent effects of CB1 cannabinoid gene disruption on anxiety‐like and social behaviour in mice

  2004cites this paper
• Sex differences in Mongolian gerbils in four tests of anxiety.

  2004cites this paper
• Os efeitos farmacológicos de drogas ditas ansiolíticas e ansiogênicas administradas em ratos testados no labirinto em cruz elevado na presença e ausência de luminosidade

  2004cites this paper
• Behavioural screening in mutagenised mice--in search for novel animal models of psychiatric disorders.

  2003cites this paper
• Longitudinal study of daily variation of rats' behavior in the elevated plus-maze.

  2003cites this paper
• Anxiolytic effects of the novel anti-epileptic drug levetiracetam in the elevated plus-maze test in the rat.

  2003cites this paper
• ‘One‐trial sensitization’ to the anxiolytic‐like effects of cannabinoid receptor antagonist SR141716A in the mouse elevated plus‐maze

  2003cites this paper
• Excitotoxic lesions of the medial prefrontal cortex attenuate fear responses in the elevated-plus maze, social interaction and shock probe burying tests.

  2003cites this paper
• Sex differences in serotonergic activity in dorsal and median raphe nucleus.

  2003cites this paper
• Testing for anxiety

  2003cites this paper
• The influence of competitive status (winner/loser) on the behavior of male rats in three models of anxiety

  2002cites this paper