Age-related differences in apoptosis with disuse atrophy in soleus muscle.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  American Journal of Physiology. Regulatory Integrative and Comparative Physiology

• Publication date

  2005-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPREGU.00576.2004PMID 15650125
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Id2 and p53 participate in apoptosis during unloading-induced muscle atrophy.

  2005cited by this paper
• Aging influences cellular and molecular responses of apoptosis to skeletal muscle unloading.

  2005cited by this paper
• Skeletal muscle gene expression in space‐flown rats

  2004cited by this paper
• Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12.

  2004influential reference
• Satellite cell regulation of muscle mass is altered at old age.

  2004influential reference
• Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production–DNA damage mechanism?

  2004cited by this paper
• Cytoplasm-to-myonucleus ratios and succinate dehydrogenase activities in adult rat slow and fast muscle fibers

  2004cited by this paper
• Mitochondrial effectors in caspase‐independent cell death

  2004cited by this paper
• Apoptosis-inducing factor (AIF): caspase-independent after all

  2004cited by this paper
• Early‐onset calorie restriction conserves fiber number in aging rat skeletal muscle

  2004cited by this paper
• Mitochondrial regulation of apoptosis.

  2003influential reference
• The calpains in aging and aging-related diseases.

  2003cited by this paper
• Global analysis of gene expression patterns during disuse atrophy in rat skeletal muscle

  2003cited by this paper
• Denervation stimulates apoptosis but not Id2 expression in hindlimb muscles of aged rats.

  2003cited by this paper
• Hindlimb unloading increases oxidative stress and disrupts antioxidant capacity in skeletal muscle.

  2003cited by this paper
• Role of apoptosis in sarcopenia.

  2003cited by this paper
• Notch-Mediated Restoration of Regenerative Potential to Aged Muscle

  2003influential reference
• Cellular and molecular basis of age-related sarcopenia.

  2002cited by this paper
• Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle

  2002cited by this paper
• Maintenance of muscle mass is not dependent on the calcineurin-NFAT pathway.

  2002cited by this paper
• Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria.

  2002cited by this paper
• Apoptosis in heart and skeletal muscle.

  2002cited by this paper
• Apoptosis in skeletal muscle with aging.

  2002influential reference
• Aging and the Role of Reactive Nitrogen Species

  2002cited by this paper
• A rat resistance exercise regimen attenuates losses of musculoskeletal mass during hindlimb suspension.

  2002cited by this paper
• Increased antioxidant capacity does not attenuate muscle atrophy caused by unweighting.

  2002cited by this paper
• Potential role for Id myogenic repressors in apoptosis and attenuation of hypertrophy in muscles of aged rats.

  2002cited by this paper
• Apoptosis and aging: role of the mitochondria.

  2001cited by this paper
• Bid Is Cleaved by Calpain to an Active Fragment in Vitro and during Myocardial Ischemia/Reperfusion*

  2001cited by this paper
• Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation

  2001cited by this paper
• Endonuclease G is an apoptotic DNase when released from mitochondria

  2001cited by this paper
• Recovery of muscles of old rats after hindlimb immobilisation by external fixation is impaired compared with those of young rats.

  2001cited by this paper
• Does oxidative damage to DNA increase with age?

  2001cited by this paper
• Aging of skeletal muscle: a 12-yr longitudinal study.

  2000cited by this paper
• Skeletal muscle regeneration and the mitotic clock.

  2000cited by this paper
• The Effect of Ciprofloxacin on Tendon, Paratenon, and Capsular Fibroblast Metabolism *

  2000cited by this paper
• Nuclear DNA fragmentation and morphological alterations in adult rabbit skeletal muscle after short-term immobilization

  2000cited by this paper
• Cell death in denervated skeletal muscle is distinct from classical apoptosis

  2000cited by this paper
• Age dependent apoptosis and loss of rhabdosphincter cells.

  2000cited by this paper
• Mechanisms leading to restoration of muscle size with exercise and transplantation after spinal cord injury.

  2000cited by this paper
• Lower recovery of muscle protein lost during starvation in old rats despite a stimulation of protein synthesis.

  1999cited by this paper
• Mammalian caspases: structure, activation, substrates, and functions during apoptosis.

  1999cited by this paper
• Myonuclear domains in muscle adaptation and disease

  1999cited by this paper
• Apoptosis in skeletal myocytes of patients with chronic heart failure is associated with exercise intolerance.

  1999cited by this paper
• Activated satellite cells fail to restore myonuclear number in spinal cord transected and exercised rats.

  1999influential reference
• Modulation of life and death by the TNF receptor superfamily

  1998cited by this paper
• Influences of Caloric Restriction on Age‐associated Skeletal Muscle Fiber Characteristics and Mitochondrial Changes in Rats and Mice a

  1998cited by this paper
• Maintenance of myonuclear domain size in rat soleus after overload and growth hormone/IGF-I treatment.

  1998cited by this paper
• Early changes in muscle fiber size and gene expression in response to spinal cord transection and exercise.

  1998cited by this paper
• Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle

  1997cited by this paper
• Apoptosis: a mechanism contributing to remodeling of skeletal muscle in response to hindlimb unweighting.

  1997cited by this paper
• Pathologic Characterization of Brown Norway, Brown Norway × Fischer 344, and Fischer 344 × Brown Norway Rats With Relation to Age

  1996cited by this paper
• Long-term dietary restriction in older-aged rhesus monkeys: effects on insulin resistance.

  1995cited by this paper
• Weight-bearing effects on skeletal muscle during and after simulated bed rest.

  1995cited by this paper
• Cell culture systems as tools for studying age-related changes in skeletal muscle.

  1995cited by this paper
• Plasticity of myonuclear number in hypertrophied and atrophied mammalian skeletal muscle fibers.

  1995cited by this paper
• Levels of the mitochondrial endonuclease during rat cardiac development implicate a role for the enzyme in repair of oxidative damage in mitochondrial DNA.

  1994cited by this paper
• Skeletal muscle weakness in old age: underlying mechanisms.

  1994cited by this paper
• Ageing and human muscle: observations from Sweden.

  1993cited by this paper
• Atrophy of the soleus muscle by hindlimb unweighting.

  1990cited by this paper
• Spherical reflector as an electromagnetic‐missile launcher

  1990cited by this paper
• Accelerated age-related decline in replicative life-span of Duchenne muscular dystrophy myoblasts: Implications for cell and gene therapy

  1990cited by this paper
• Epidemiologic and methodologic problems in determining nutritional status of older persons. Proceedings of a conference. Albuquerque, New Mexico, October 19-21, 1988.

  1989cited by this paper
• Summary comments : Epidemiological and methodological problem in determining nutritional status of older persons

  1989cited by this paper
• Changes in fiber composition of soleus muscle during rat hindlimb suspension.

  1988cited by this paper
• Time course of soleus muscle myosin expression during hindlimb suspension and recovery.

  1987cited by this paper
• Morphometric analyses on the muscles of exercise trained and untrained dogs.

  1983cited by this paper
• A model for hypokinesia: effects on muscle atrophy in the rat.

  1980cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper

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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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