A conserved dedicated olfactory circuit for detecting harmful microbes in Drosophila.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Cell

• Publication date

  2012-12-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.cell.2012.09.046PMID 23217715
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A high-throughput behavioral paradigm for Drosophila olfaction - The Flywalk

  2012influential reference
• Spatial representation of odorant valence in an insect brain.

  2012cited by this paper
• Phosphorylation via PKC Regulates the Function of the Drosophila Odorant Co-Receptor

  2011cited by this paper
• Functional agonism of insect odorant receptor ion channels

  2011influential reference
• Evolution of insect olfaction.

  2011cited by this paper
• Flying the Fly: Long-range Flight Behavior of Drosophila melanogaster to Attractive Odors

  2010influential reference
• A dimorphic pheromone circuit in Drosophila from sensory input to descending output

  2010cited by this paper
• A deceptive pollination system targeting drosophilids through olfactory mimicry of yeast.

  2010influential reference
• Physiological and morphological characterization of local interneurons in the Drosophila antennal lobe.

  2010influential reference
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  2009cited by this paper
• Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators

  2009cited by this paper
• Variant ionotropic glutamate receptors as chemosensory receptors in Drosophila.

  2009influential reference
• Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels

  2008cited by this paper
• An internal thermal sensor controlling temperature preference in Drosophila

  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• Olfactory processing and behavior downstream from highly selective receptor neurons

  2007influential reference
• Molecular evolution of Drosophila odorant receptor genes.

  2007cited by this paper
• Molecular architecture of smell and taste in Drosophila.

  2007cited by this paper
• Receptors and neurons for fly odors in Drosophila.

  2007cited by this paper
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  2005cited by this paper
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  2005influential reference
• Molecular, anatomical, and functional organization of the Drosophila olfactory system.

  2005influential reference
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  2004influential reference
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  2001influential reference
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  1999cited by this paper
• Secretion of FK506/FK520 and rapamycin by Streptomyces inhibits the growth of competing Saccharomyces cerevisiae and Cryptococcus neoformans.

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  1999cited by this paper
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  1997cited by this paper
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• Molecular phylogeny and divergence times of drosophilid species.

  1995cited by this paper
• Identification of geosmin as a volatile metabolite of Penicillium expansum

  1992cited by this paper
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  1986cited by this paper
• Geosmin, an earthy‐smelling substance isolated from actinomycetes

  1967cited by this paper
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  1965cited by this paper
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  1959cited by this paper
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  1953cited by this paper

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