Familial adenomatous polyposis in pediatrics: natural history, emerging surveillance and management protocols, chemopreventive strategies, and areas of ongoing debate

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Familial Cancer

• Publication date

  2016-04-07

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s10689-016-9905-5PMID 27056662
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chemoprevention of familial adenomatous polyposis

  2016cited by this paper
• Functional outcomes and complications after restorative proctocolectomy and ileal pouch anal anastomosis in the pediatric population.

  2014cited by this paper
• Attenuated familial adenomatous polyposis manifests as autosomal dominant late-onset colorectal cancer

  2014cited by this paper
• Familial adenomatous polyposis: ileo-anal pouch versus ileo-rectal anastomosis

  2014cited by this paper
• Fatal extraintestinal adrenal malignancy in a 12-year-old girl with familial adenomatous polyposis.

  2014cited by this paper
• Risk of desmoid tumours after open and laparoscopic colectomy in patients with familial adenomatous polyposis

  2014cited by this paper
• Results of a prospective thyroid ultrasound screening program in adenomatous polyposis patients.

  2014cited by this paper
• The natural history of familial adenomatous polyposis syndrome: a 24 year review of a single center experience in screening, diagnosis, and outcomes.

  2014cited by this paper
• Congenital hypertrophy of retinal pigment epithelium (CHRPE) in patients with familial adenomatous polyposis (FAP); a polyposis registry experience

  2014cited by this paper
• APC-Associated Polyposis Conditions

  2014cited by this paper
• APC promoter 1B deletion in familial polyposis—implications for mutation‐negative families

  2014cited by this paper
• Thyroid cancer complicating familial adenomatous polyposis: mutation spectrum of at-risk individuals

  2013cited by this paper
• The APC p.I1307K polymorphism is a significant risk factor for CRC in average risk Ashkenazi Jews.

  2013cited by this paper
• Preventive effects of low-dose aspirin on colorectal adenoma growth in patients with familial adenomatous polyposis: double-blind, randomized clinical trial

  2013cited by this paper
• Berberine potently attenuates intestinal polyps growth in ApcMin mice and familial adenomatous polyposis patients through inhibition of Wnt signalling

  2013cited by this paper
• Prospective enteroscopic evaluation of jejunal polyposis in patients with familial adenomatous polyposis and advanced duodenal polyposis

  2012cited by this paper
• Colorectal Cancer Chemoprevention: Is This the Future of Colorectal Cancer Prevention?

  2012influential reference
• Evaluation of Guidelines for Management of Familial Adenomatous Polyposis in a Multicenter Pediatric Cohort

  2011cited by this paper
• Chemoprevention in familial adenomatous polyposis.

  2011cited by this paper
• Prevalence of gastric and duodenal polyps and risk factors for duodenal neoplasm in korean patients with familial adenomatous polyposis.

  2011cited by this paper
• A Randomized Placebo-Controlled Prevention Trial of Aspirin and/or Resistant Starch in Young People with Familial Adenomatous Polyposis

  2011cited by this paper
• Jejunal cancer in patients with familial adenomatous polyposis.

  2010cited by this paper
• The impact of screening and genetic registration on mortality and colorectal cancer incidence in familial adenomatous polyposis

  2010cited by this paper
• The Safety and Efficacy of Celecoxib in Children With Familial Adenomatous Polyposis

  2010cited by this paper
• Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposis

  2010cited by this paper
• Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice.

  2010cited by this paper
• Small-bowel diagnosis in patients with familial adenomatous polyposis: comparison of push enteroscopy, capsule endoscopy, ileoscopy, and enteroclysis.

  2009cited by this paper
• Psychosocial Impact of Familial Adenomatous Polyposis on Young Adults: A Qualitative Study

  2009cited by this paper
• EXTRAINTESTINAL MANIFESTATIONS OF FAMILIAL ADENOMATOUS POLYPOSIS: THYROID MALIGNANT DISEASE

  2009cited by this paper
• APC or MUTYH mutations account for the majority of clinically well‐characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas

  2009influential reference
• Guidelines for the clinical management of familial adenomatous polyposis (FAP)

  2008cited by this paper
• Extra-Intestinal Manifestations of Familial Adenomatous Polyposis

  2008cited by this paper
• Fundic gland polyp dysplasia is common in familial adenomatous polyposis.

  2008cited by this paper
• Cancer Statistics, 2008

  2008cited by this paper
• Gastric Adenocarcinoma Arising from Fundic Gland Polyps in a Patient with Familial Adenomatous Polyposis Syndrome

  2008cited by this paper
• Regulation of COX and LOX by curcumin.

  2007cited by this paper
• Does early colectomy increase desmoid risk in familial adenomatous polyposis?

  2007cited by this paper
• Brain tumors in individuals with familial adenomatous polyposis

  2007cited by this paper
• n-3 polyunsaturated fatty acids and the prevention of colorectal cancer: molecular mechanisms involved.

  2007cited by this paper
• Celecoxib for the prevention of colorectal adenomatous polyps.

  2006cited by this paper
• Celecoxib for the prevention of sporadic colorectal adenomas.

  2006cited by this paper
• Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis.

  2006cited by this paper
• Meta‐analysis of observational studies of ileorectal versus ileal pouch–anal anastomosis for familial adenomatous polyposis

  2006cited by this paper
• Impact of familial adenomatous polyposis on young adults: Attitudes toward genetic testing, support, and information needs

  2006cited by this paper
• Should children at risk for familial adenomatous polyposis be screened for hepatoblastoma and children with apparently sporadic hepatoblastoma be screened for APC germline mutations?

  2006cited by this paper
• Psychological impact of genetic testing for cancer susceptibility: an update of the literature

  2005cited by this paper
• Meat, fish, and colorectal cancer risk: the European Prospective Investigation into cancer and nutrition.

  2005cited by this paper
• Large deletions of the APC gene in 15% of mutation‐negative patients with classical polyposis (FAP): A Belgian study

  2005influential reference
• Colorectal cancer in two pre-teenage siblings with familial adenomatous polyposis

  2005cited by this paper
• Surveillance and management of upper gastrointestinal disease in Familial Adenomatous Polyposis

  2005cited by this paper
• Current ideas in desmoid tumours

  2005cited by this paper
• Duodenal adenomatosis in familial adenomatous polyposis

  2004cited by this paper
• Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial.

  2003cited by this paper
• A randomized trial of aspirin to prevent colorectal adenomas.

  2003cited by this paper
• Genetic testing for hereditary colorectal cancer in children: Long‐term psychological effects

  2003cited by this paper
• A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis

  2002cited by this paper
• Primary chemoprevention of familial adenomatous polyposis with sulindac.

  2002cited by this paper
• Nonsteroidal anti-inflammatory drugs, apoptosis, and colon-cancer chemoprevention.

  2002cited by this paper
• Primary chemoprevention of familial adenomatous polyposis with sulindac

  2002cited by this paper
• Major study commencing into genetic discrimination in Australia.

  2002cited by this paper
• Predictive genetic testing in children and adults: a study of emotional impact

  2001cited by this paper
• Duodenal adenomatosis in familial adenomatous polyposis coli

  2001cited by this paper
• The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis.

  2000cited by this paper
• Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis.

  2000cited by this paper
• Cumulative risk of developing polyps or malignancy at the ileal pouch-anal anastomosis in patients with familial adenomatous polyposis

  1999cited by this paper
• Gastric adenocarcinoma associated with fundic gland polyps in a patient with attenuated familial adenomatous polyposis

  1999cited by this paper
• Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK signalling complex

  1999cited by this paper
• Desmoid tumours complicating familial adenomatous polyposis

  1999cited by this paper
• Cyclooxygenase regulates angiogenesis induced by colon cancer cells.

  1998cited by this paper
• The use and interpretation of commercial APC gene testing for familial adenomatous polyposis.

  1997cited by this paper
• Fish, n-3 fatty acids and human colorectal and breast cancer mortality.

  1995cited by this paper
• Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2.

  1995cited by this paper
• Causes of death and postsurgical survival in familial adenomatous polyposis: results from the Italian Registry. Italian Registry of Familial Polyposis Writing Committee.

  1994cited by this paper
• Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis.

  1993cited by this paper
• Randomized controlled trial of the effect of sulindac on duodenal and rectal polyposis and cell proliferation in patients with familial adenomatous polyposis

  1993cited by this paper
• The risk of upper gastrointestinal cancer in familial adenomatous polyposis.

  1992cited by this paper
• Sulindac causes regression of rectal polyps in familial adenomatous polyposis.

  1991cited by this paper
• Mortality in patients with familial adenomatous polyposis

  1990cited by this paper
• Upper gastrointestinal cancer in patients with familial adenomatous polyposis.

  1989cited by this paper
• Cancer statistics

  1989cited by this paper
• Natural history of gastric adenomas in patients with familial adenomatosis Coli/Gardner's syndrome

  1988cited by this paper
• Oral penicillin in gonorrhoea.

  1946cited by this paper

• Japanese society for cancer of the colon and rectum (JSCCR) guidelines 2024 for the clinical practice of hereditary colorectal cancer

  2025cites this paper
• Polipose Adenomatosa Familiar: o infamiliar de uma herança genética

  2025cites this paper
• Mechanisms of Action of Phytoestrogens and Their Role in Familial Adenomatous Polyposis

  2024cites this paper
• Current practice of cancer predisposition testing in pediatric patients with CNS tumors in the United States

  2023cites this paper
• Intensive endoscopic resection for downstaging of polyp burden in patients with familial adenomatous polyposis (J-FAPP Study III): a multicenter prospective interventional study

  2022cites this paper
• Metformin combined with endoscopic therapy in patients with familial polyposis associated with carcinoma: A case report

  2022cites this paper
• The Role of Pharmacotherapeutic Agents in Children with Desmoid Tumors

  2022cites this paper
• Adenomatous polyposis syndrome

  2022cites this paper
• Paediatric polyposis syndromes: burden of disease and current concepts

  2021cites this paper
• Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2020 for the Clinical Practice of Hereditary Colorectal Cancer

  2021cites this paper
• Colorectal carcinoma in children and adolescents.

  2021cites this paper
• Inherited Follicular Epithelial-Derived Thyroid Carcinomas: From Molecular Biology to Histological Correlates

  2021cites this paper
• Characterizing Pediatric Familial Adenomatous Polyposis in Patients Undergoing Colectomy in the United States.

  2021cites this paper
• Pediatric Neuro-Oncology.

  2021cites this paper
• Predictive Testing for Tumor Predisposition Syndromes in Pediatric Relatives: An Asian Experience

  2020cites this paper
• Hepatoblastoma in Infants Born to Parents with Familial Adenomatous Polyposis

  2020cites this paper
• Sporadic pediatric severe familial adenomatous polyposis: A case report.

  2020cites this paper
• Abstract. Familial adenomatous polyposis (FAP) is an auto‐ somal dominant hereditary precancerous condition caused by germline pathogenetic variants in the tumor suppressor adeno‐ matous polyposis coli (APC) gene. Patients with FAP develop multiple gastrointestinal adenomatous polyps usually at the

  2020cites this paper
• Polyp Progression in Paediatric Patients with Familial Adenomatous Polyposis - A Single Centre Experience.

  2020cites this paper
• Familial adenomatous colorectal polyposis complicated by colonic obturation: a clinical case

  2020cites this paper
• Prevalence of Gastroduodenal Polyps in Children With Familial Adenomatous Polyposis

  2020cites this paper
• Identification of aggressive Gardner syndrome phenotype associated with a de novo APC variant, c.4666dup

  2019cites this paper
• Management of Familial Adenomatous Polyposis in Children and Adolescents: Position Paper From the ESPGHAN Polyposis Working Group.

  2019cites this paper
• Genetics of Common Pediatric Brain Tumors.

  2019cites this paper
• ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer

  2019cites this paper
• Pediatric Spindle Cell Tumors

  2019cites this paper
• Intestinal Polyps

  2019cites this paper
• Inherited Colorectal Cancer and the Genetics of Colorectal Cancer

  2019cites this paper
• Medulloblastomas associated with APC germline pathogenic variant share the good prognosis of CTNNB1 mutated medulloblastomas.

  2019cites this paper
• Multiple pilomatrixomas in a survivor of WNT‐activated medulloblastoma leading to the discovery of a germline APC mutation and the diagnosis of familial adenomatous polyposis

  2018cites this paper
• GIANT COLONIC POLYPS IN PEDIATRIC PATIENT WITH FAMILIAL ADENOMATOUS POLYPOSIS

  2018influential citation
• Clinically Relevant Anti-Inflammatory Agents for Chemoprevention of Colorectal Cancer: New Perspectives

  2018cites this paper
• WEO Newsletter

  2018cites this paper
• Short-term outcomes in children undergoing restorative proctocolectomy with ileal-pouch anal anastomosis.

  2018cites this paper
• Hepatoblastoma in patients with molecularly proven familial adenomatous polyposis: Clinical characteristics and rationale for surveillance screening

  2018cites this paper
• Cancer Screening Recommendations and Clinical Management of Inherited Gastrointestinal Cancer Syndromes in Childhood

  2017cites this paper