Behavioral, neurochemical, and neuroimmune changes in NRF2 knockout mice following early postnatal exposure to valproic acid

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.7282/T39S1PN0
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential sensitivity of Pak5, Pak6, and Pak5/Pak6 double-knockout mice to the stimulant effects of amphetamine and exercise-induced alterations in body weight

  2014cited by this paper
• Excitatory GABA: How a Correct Observation May Turn Out to be an Experimental Artifact

  2012cited by this paper
• Traumatic Alterations in GABA Signaling Disrupt Hippocampal Network Activity in the Developing Brain

  2012cited by this paper
• Immune surveillance in the central nervous system

  2012cited by this paper
• Distinct development of GABA system in the ventral and dorsal horns in the embryonic mouse spinal cord.

  2012influential reference
• The cytoprotective role of the Keap1–Nrf2 pathway

  2011cited by this paper
• Expression of Keap1-Nrf2 system and antioxidative proteins in mouse brain after transient middle cerebral artery occlusion.

  2011cited by this paper
• Valproic acid inhibits neural progenitor cell death by activation of NF-κB signaling pathway and up-regulation of Bcl-XL

  2011influential reference
• Amelioration of behavioral aberrations and oxidative markers by green tea extract in valproate induced autism in animals.

  2011influential reference
• The Role of Microglia in the Healthy Brain

  2011cited by this paper
• The real mechanism of VPA-induced hyperammonemia remains unknown.

  2011cited by this paper
• Molecular and Therapeutic Potential and Toxicity of Valproic Acid

  2010cited by this paper
• Different Susceptibility to the Parkinson's Toxin MPTP in Mice Lacking the Redox Master Regulator Nrf2 or Its Target Gene Heme Oxygenase-1

  2010influential reference
• In the Adult Hippocampus, Chronic Nerve Growth Factor Deprivation Shifts GABAergic Signaling from the Hyperpolarizing to the Depolarizing Direction

  2010cited by this paper
• Crucial Role of Nrf3 in Smooth Muscle Cell Differentiation From Stem Cells

  2010cited by this paper
• Neonatal quinpirole treatment enhances locomotor activation and dopamine release in the nucleus accumbens core in response to amphetamine treatment in adulthood

  2010influential reference
• Neuronal activity in vitro and the in vivo reality: the role of energy homeostasis.

  2010cited by this paper
• Amphetamine toxicities

  2010influential reference
• The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice

  2010influential reference
• Role of Nrf1 in antioxidant response element-mediated gene expression and beyond.

  2010cited by this paper
• Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease

  2010cited by this paper
• Nrf3‐deficient mice are not protected against acute lung and adipose tissue damages induced by butylated hydroxytoluene

  2010cited by this paper
• A Sensitive Period of Mice Inhibitory System to Neonatal GABA Enhancement by Vigabatrin is Brain Region Dependent

  2010cited by this paper
• Sedative and Anticonvulsant Drugs Suppress Postnatal Neurogenesis

  2009influential reference
• A study on the fate of curcumin in the rat.

  2009cited by this paper
• Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions.

  2009cited by this paper
• The expression of NF-E2-related factor 2 in the rat brain after traumatic brain injury.

  2009influential reference
• Role of Nrf2 in Protection against Traumatic Brain Injury in Mice

  2009cited by this paper
• Nrf2:INrf2 (Keap1) signaling in oxidative stress.

  2009cited by this paper
• The Nrf3 Transcription Factor Is a Membrane-bound Glycoprotein Targeted to the Endoplasmic Reticulum through Its N-terminal Homology Box 1 Sequence*

  2009cited by this paper
• Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes*

  2008cited by this paper
• Amphetamine causes dopamine depletion and cell death in the mouse olfactory bulb.

  2008cited by this paper
• Induction of class I antigen processing components in oligodendroglia and microglia during viral encephalomyelitis

  2008cited by this paper
• The role and the mechanism of γ-aminobutyric acid during central nervous system development

  2008cited by this paper
• VPA-induced apoptosis and behavioral deficits in neonatal mice.

  2008cited by this paper
• Gender-specific behavioral and immunological alterations in an animal model of autism induced by prenatal exposure to valproic acid.

  2008influential reference
• Activation of Nrf2 in defense against cadmium-induced oxidative stress.

  2008cited by this paper
• Transcription Factor Nrf2 Protects the Brain From Damage Produced by Intracerebral Hemorrhage

  2007influential reference
• Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity

  2007cited by this paper
• Disruption of the vasopressin 1b receptor gene impairs the attack component of aggressive behavior in mice

  2007cited by this paper
• GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations.

  2007cited by this paper
• The neurobiological bases for development of pharmacological treatments of aggressive disorders.

  2007cited by this paper
• Nrf2-mediated protection against 6-hydroxydopamine.

  2007influential reference
• Peer-mediated social skills training program for young children with high-functioning autism.

  2007cited by this paper
• Behavioral and neurochemical sensitization to amphetamine following early postnatal administration of methylmercury (MeHg).

  2007influential reference
• Microglia activation in retinal degeneration

  2007cited by this paper
• Enhanced spontaneous and benzo(a)pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice.

  2007cited by this paper
• Visual field defect during therapy with valproic‐acid

  2007cited by this paper
• Fetal Exposure to GABA‐Acting Antiepileptic Drugs Generates Hippocampal and Cortical Dysplasias

  2007cited by this paper
• Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.

  2007cited by this paper
• Developmental localization of potassium chloride co-transporter 2 (KCC2) in the Purkinje cells of embryonic mouse cerebellum.

  2007cited by this paper
• Hyperammonemia-induced toxicity for the developing central nervous system.

  2007cited by this paper
• In vivo modulation of the Parkinsonian phenotype by Nrf2.

  2006cited by this paper
• Valproic Acid Increases Conservative Homologous Recombination Frequency and Reactive Oxygen Species Formation: A Potential Mechanism for Valproic Acid-Induced Neural Tube Defects

  2006influential reference
• Valproic acid-induced gene expression through production of reactive oxygen species.

  2006influential reference
• Control of microglial neurotoxicity by the fractalkine receptor

  2006cited by this paper
• Arsenic Induces NAD(P)H-quinone Oxidoreductase I by Disrupting the Nrf2·Keap1·Cul3 Complex and Recruiting Nrf2·Maf to the Antioxidant Response Element Enhancer*

  2006cited by this paper
• Microglia and inflammation: impact on developmental brain injuries.

  2006cited by this paper
• Regulation of inflammation and redox signaling by dietary polyphenols.

  2006cited by this paper
• Negative regulation of the Nrf1 transcription factor by its N-terminal domain is independent of Keap1: Nrf1, but not Nrf2, is targeted to the endoplasmic reticulum.

  2006cited by this paper
• A New Neurobehavioral Model of Autism in Mice: Pre- and Postnatal Exposure to Sodium Valproate

  2006influential reference
• Behavioral and Emotional Problems in Young People with Pervasive Developmental Disorders: Relative Prevalence, Effects of Subject Characteristics, and Empirical Classification

  2006cited by this paper
• Nrf2 Possesses a Redox-sensitive Nuclear Exporting Signal in the Neh5 Transactivation Domain*

  2006influential reference
• Dimerization of Substrate Adaptors Can Facilitate Cullin-mediated Ubiquitylation of Proteins by a “Tethering” Mechanism

  2006influential reference
• Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo

  2005cited by this paper
• Transcription Factor Nrf2 Plays a Pivotal Role in Protection against Elastase-Induced Pulmonary Inflammation and Emphysema1

  2005influential reference
• Functions and distribution of NQO1 in human bone marrow: potential clues to benzene toxicity.

  2005cited by this paper
• Curcumin Inhibits Immunostimulatory Function of Dendritic Cells: MAPKs and Translocation of NF-κB as Potential Targets1

  2005cited by this paper
• Comparison of (−)-Epigallocatechin-3-Gallate Elicited Liver and Small Intestine Gene Expression Profiles Between C57BL/6J Mice and C57BL/6J/Nrf2 (−/−) Mice

  2005cited by this paper
• Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells.

  2005cited by this paper
• Maternal exposure to the antiepileptic drug vigabatrin affects postnatal development in the rat

  2005cited by this paper
• Glutathione transferases.

  2005influential reference
• Cerebellar function in autism: functional magnetic resonance image activation during a simple motor task.

  2004cited by this paper
• Risperidone reduction of amphetamine-induced self-injurious behavior in mice.

  2004cited by this paper
• Combined toxicity of prenatal bacterial endotoxin exposure and postnatal 6-hydroxydopamine in the adult rat midbrain.

  2004cited by this paper
• HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS

  2004cited by this paper
• Methamphetamine Neurotoxicity in Dopamine Nerve Endings of the Striatum Is Associated with Microglial Activation

  2004cited by this paper
• Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes.

  2004cited by this paper
• Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene

  2004cited by this paper
• Nrf3 Negatively Regulates Antioxidant-response Element-mediated Expression and Antioxidant Induction of NAD(P)H:Quinone Oxidoreductase1 Gene*

  2004cited by this paper
• Microglial activation precedes dopamine terminal pathology in methamphetamine-induced neurotoxicity.

  2004cited by this paper
• Oxidative Stress Sensor Keap1 Functions as an Adaptor for Cul3-Based E3 Ligase To Regulate Proteasomal Degradation of Nrf2

  2004cited by this paper
• Social motivation is reduced in vasopressin 1b receptor null mice despite normal performance in an olfactory discrimination task.

  2004cited by this paper
• Hemicerebellectomy and motor behaviour in rats

  2004cited by this paper
• Complexity of CNC Transcription Factors As Revealed by Gene Targeting of the Nrf3 Locus

  2004cited by this paper
• The use of a plus-maze to measure anxiety in the mouse

  2004cited by this paper
• Keap1-dependent Proteasomal Degradation of Transcription Factor Nrf2 Contributes to the Negative Regulation of Antioxidant Response Element-driven Gene Expression*

  2003influential reference
• Cancer chemoprevention with dietary phytochemicals

  2003cited by this paper
• Curcumin alters EpRE and AP‐1 binding complexes and elevates glutamate‐cysteine ligase gene expression

  2003cited by this paper
• Anticonvulsant valproic acid inhibits cardiomyocyte differentiation of embryonic stem cells by increasing intracellular levels of reactive oxygen species.

  2003influential reference
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• Relationship between methamphetamine-induced dopamine release, hyperthermia, self-injurious behaviour and long term dopamine depletion in BALB/c and C57BL/6 mice.

  2003cited by this paper
• Selective neurodegeneration of hippocampus and entorhinal cortex correlates with spatial learning impairments in rats with bilateral ibotenate lesions of ventral subiculum.

  2003cited by this paper
• Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice.

  2003cited by this paper
• Brain Imaging Studies in Mood and Anxiety Disorders

  2003cited by this paper
• Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element.

  2003cited by this paper
• Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

  2003cited by this paper
• The effects of antiepileptic drugs on spatial learning and hippocampal protein kinase C gamma in immature rats.

  2002cited by this paper
• Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galangin.

  2002cited by this paper
• A Sulforaphane Analogue That Potently Activates the Nrf2-dependent Detoxification Pathway*

  2002cited by this paper

• No citing papers are available for this paper.