Regulation of chitin synthesis in the larval midgut of Manduca sexta.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Insect Biochemistry and Molecular Biology

• Publication date

  2005-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.IBMB.2005.01.008PMID 15857758
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chitin synthase genes in Manduca sexta: characterization of a gut-specific transcript and differential tissue expression of alternately spliced mRNAs during development.

  2005cited by this paper
• Stability and zymogenic nature of chitin synthase fromCandida albicans

  2005cited by this paper
• Description of the Transcriptomes of Immune Response-Activated Hemocytes from the Mosquito Vectors Aedes aegypti and Armigeres subalbatus

  2004cited by this paper
• Characterization of two chitin synthase genes of the red flour beetle, Tribolium castaneum, and alternate exon usage in one of the genes during development.

  2004cited by this paper
• Storage and secretion of the peritrophic matrix protein Ag‐Aper1 and trypsin in the midgut of Anopheles gambiae

  2004cited by this paper
• The first direct evaluation of the two-active site mechanism for chitin synthase.

  2004cited by this paper
• Transcription regulation is demonstrated for five key enzymes in Giardia intestinalis cyst wall polysaccharide biosynthesis.

  2003cited by this paper
• Culex pipiens pipiens: characterization of immune peptides and the influence of immune activation on development of Wuchereria bancrofti.

  2003cited by this paper
• Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases

  2003cited by this paper
• Immunolocalization of chitin synthase in the tobacco hornworm

  2002cited by this paper
• Stage-specific expression of the chitin synthase DmeChSA and DmeChSB genes during the onset of Drosophila metamorphosis.

  2002cited by this paper
• Glucosamine:fructose‐6‐phosphate aminotransferase: gene characterization, chitin biosynthesis and peritrophic matrix formation in Aedes aegypti

  2002cited by this paper
• Sequence of a cDNA and expression of the gene encoding a putative epidermal chitin synthase of Manduca sexta.

  2002cited by this paper
• Insect Midgut as a Site for Insecticide Detoxification and Resistance

  2001cited by this paper
• The Crystal Structures of Apo and Complexed Saccharomyces cerevisiae GNA1 Shed Light on the Catalytic Mechanism of an Amino-sugar N-Acetyltransferase*

  2001cited by this paper
• Chitin synthesis and inhibition: a revisit.

  2001cited by this paper
• Biochemical Sites of Insecticide Action and Resistance

  2001cited by this paper
• Reduced virulence of Candida albicans mutants lacking the GNA1 gene encoding glucosamine-6-phosphate acetyltransferase.

  2000cited by this paper
• The yeast Chs4 protein stimulates the trypsin-sensitive activity of chitin synthase 3 through an apparent protein-protein interaction.

  2000cited by this paper
• Genetics of Mosquito Vector Competence

  2000cited by this paper
• Decreased UDP‐GlcNAc levels abrogate proliferation control in EMeg32‐deficient cells

  2000cited by this paper
• Cloning and characterization of a chitin synthase cDNA from the mosquito Aedes aegypti.

  2000cited by this paper
• Aedes aegypti dopa decarboxylase: gene structure and regulation

  2000cited by this paper
• Insect chitin synthase cDNA sequence, gene organization and expression.

  2000cited by this paper
• Biochemistry of chitin synthase.

  1999influential reference
• Structure and mechanism of action of the histone acetyltransferase Gcn5 and similarity to other N-acetyltransferases.

  1999cited by this paper
• The Candida albicans CHS4 gene complements a Saccharomyces cerevisiae skt5/chs4 mutation and is involved in chitin biosynthesis.

  1999cited by this paper
• Saccharomyces cerevisiae GNA1, an Essential Gene Encoding a Novel Acetyltransferase Involved in UDP-N-acetylglucosamine Synthesis*

  1999cited by this paper
• Positive Regulation of Adenylyl Cyclase Activity by a GαiHomolog inNeurospora crassa

  1999cited by this paper
• Partial purification and kinetic properties of three different D-glucosamine 6-P:N-acetyltransferase forms from human placenta.

  1998cited by this paper
• Mitochondrial reactive oxygen species trigger hypoxia-induced transcription.

  1998cited by this paper
• Peritrophic matrix structure and function.

  1997cited by this paper
• A Septin-based Hierarchy of Proteins Required for Localized Deposition of Chitin in the Saccharomyces cerevisiae Cell Wall

  1997cited by this paper
• Peritrophic matrix structure and function.

  1997cited by this paper
• Characterization of CHS4 (CAL2), a Gene of Saccharomyces cerevisiae Involved in Chitin Biosynthesis and Allelic to SKT5 and CSD4

  1997cited by this paper
• Sense and antisense RNA for the membrane associated 40 kDa subunit M40 of the insect V‐ATPase

  1997cited by this paper
• GCN5-related histone N-acetyltransferases belong to a diverse superfamily that includes the yeast SPT10 protein.

  1997cited by this paper
• Yeast chitin synthases 1 and 2 consist of a non-homologous and dispensable N-terminal region and of a homologous moiety essential for function

  1996cited by this paper
• Trypsin and aminopeptidase gene expression is affected by age and food composition in Anopheles gambiae.

  1996cited by this paper
• Applications of Solids NMR to the Analysis of Insect Sclerotized Structures

  1995cited by this paper
• Dietary control of late trypsin gene transcription in Aedes aegypti.

  1994cited by this paper
• Quantitative determination of monosaccharides in glycoproteins by high-performance liquid chromatography with highly sensitive fluorescence detection.

  1994cited by this paper
• Evolution and multi-functionality of the chitin system.

  1994cited by this paper
• Chitin synthase 3 from yeast has zymogenic properties that depend on both the CAL1 and the CAL3 genes.

  1994cited by this paper
• Sequence of three cDNAs encoding an alkaline midgut trypsin from Manduca sexta.

  1994cited by this paper
• A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples.

  1993cited by this paper
• Purification and characterization of membrane-bound chitin synthase.

  1993cited by this paper
• Genetics and molecular biology of chitin synthesis in fungi.

  1993cited by this paper
• Linkage map for Aedes aegypti using restriction fragment length polymorphisms.

  1993cited by this paper
• The role of the mosquito peritrophic membrane in bloodmeal digestion and infectivity of Plasmodium species.

  1992cited by this paper
• Sequence analysis of a mosquito ribosomal protein rpL8 gene and its upstream regulatory region

  1992cited by this paper
• Physiology of the insect epidermis

  1991cited by this paper
• Proteinase B is, indeed, not required for chitin synthetase 1 function in Saccharomyces cerevisiae.

  1991cited by this paper
• Growth and differentiation of the larval midgut epithelium during molting in the moth, Manduca sexta.

  1991influential reference
• Isolation, purification, and characterization of glucosamine-6-phosphate-N-acetylase from pig liver.

  1990cited by this paper
• Isolation of goblet cell apical membrane from tobacco hornworm midgut and purification of its vacuolar-type ATPase.

  1990cited by this paper
• The mouse ribosomal protein L7 gene. Its primary structure and functional analysis of the promoter region.

  1990cited by this paper
• Substitute blood meal for investigating and maintaining Aedes aegypti (Diptera: Culicidae).

  1990cited by this paper
• A vacuolar-type ATPase, partially purified from potassium transporting plasma membranes of tobacco hornworm midgut.

  1989cited by this paper
• Time and site of assembly of the peritrophic membrane of the mosquito Aedes aegypti

  1988cited by this paper
• Chitin synthesis in insect cell lines

  1988cited by this paper
• Glucosamine 6-phosphate acetylase in rat ascites hepatomas.

  1986cited by this paper
• Three forms of rat liver glucosamine 6-phosphate acetylase and the changes in their levels during development.

  1985cited by this paper
• Brugia pahangi: Exsheathment and Midgut Penetration in Aedes aegypti

  1984cited by this paper
• Isolation of chitin synthetase from Saccharomyces cerevisiae. Purification of an enzyme by entrapment in the reaction product.

  1984cited by this paper
• [8] Reassessment of Ellman's reagent

  1983cited by this paper
• Cellular location of N-acetyltransfer activities toward glucosamine and glucosamine-6-phosphate in cultured human skin fibroblasts.

  1983cited by this paper
• Properties of Tribolium gut chitin synthetase

  1980influential reference
• Characterization of a chitin synthase from the stable fly, Stomoxys calcitrans (L.)

  1980influential reference
• Inhibition of Tribolium gut chitin synthetase.

  1980cited by this paper
• Septum formation, cell division, and sporulation in mutants of yeast deficient in proteinase B.

  1979cited by this paper
• The morphology and fine structure of the larval midgut of a moth (Manduca sexta) in relation to active ion transport.

  1979cited by this paper
• Chitin biosynthesis in protoplasts and subcellular fractions of Aspergillus fumigatus.

  1977cited by this paper
• The activating system of chitin synthetase from Saccharomyces cerevisiae. Purification and properties of the activating factor.

  1976cited by this paper
• Techniques for Rearing Laboratory Colonies of Tobacco Hornworms and Pink Bollworms

  1976cited by this paper
• Chitin synthetase zymogen is attached to the yeast plasma membrane.

  1975cited by this paper
• Yeast chitin synthetase. Separation of the zymogen from its activating factor and recovery of the latter in the vacuole fraction.

  1973cited by this paper
• The control of morphogenesis: an enzymatic mechanism for the initiation of septum formation in yeast.

  1971cited by this paper
• Studies on Chitin Synthesis in the Desert Locust

  1962cited by this paper

• Distinct cellular and molecular mechanisms contribute to the specificity of the two Drosophila melanogaster chitin synthases in chitin deposition

  2025cites this paper
• Xenobiotic resistance in mosquito eggs: current understanding and data gaps

  2025cites this paper
• A G-protein coupled receptor is involved in the DUOX pathway in Tribolium castaneum.

  2025cites this paper
• CHS-2 Is Involved in the Response of Aedes albopictus (Diptera: Culicidae) Larvae to Cadmium Stress by Mediating the Formation of the Peritrophic Membrane

  2025cites this paper
• First report of Needle Cast of Cathaya argyrophylla caused by Neofusicoccum parvum in China.

  2025cites this paper
• Dextran sulfate sodium and uracil induce inflammatory effects and disrupt the chitinous peritrophic matrix in the midgut of Tribolium castaneum.

  2023cites this paper
• Characterization of Chitin Synthase B Gene (HvChsb) and the Effects on Feeding Behavior in Heortia vitessoides Moore

  2023cites this paper
• Functional importance of groups I and II chitinases in cuticle chitin turnover during molting in a wood-boring beetle, Monochamus alternatus.

  2023cites this paper
• RNAi-mediated CHS-2 silencing affects the synthesis of chitin and the formation of the peritrophic membrane in the midgut of Aedes albopictus larvae

  2023cites this paper
• Detection of Chitin Synthase Mutations in Lufenuron-Resistant Spodoptera frugiperda in China

  2022cites this paper
• SERCA interacts with chitin synthase and participates in cuticular chitin biogenesis in Drosophila.

  2022cites this paper
• RNAi for chitin synthase 1 rather than 2 causes growth delay and molting defect in Henosepilachna vigintioctopunctata.

  2021cites this paper
• AOP Report: Inhibition of Chitin Synthase 1 Leading to Increased Mortality in Arthropods

  2021cites this paper
• Physiological characterization of chitin synthase A responsible for the biosynthesis of cuticle chitin in Culex pipiens pallens (Diptera: Culicidae)

  2021cites this paper
• Genome‐wide in vitro and in vivo RNAi screens reveal Fer3 to be an important regulator of kkv transcription in Drosophila

  2021cites this paper
• Physiological Characterization of the Chitin Synthase A Gene Responsible for Biosynthesis of Cuticle Chitin in Culex Pipiens Pallens (Diptera: Culicidae)

  2021cites this paper
• Chitin synthase 1 and five cuticle protein genes are involved in serosal cuticle formation during early embryogenesis to enhance eggshells in Nilaparvata lugens

  2021cites this paper
• Insect Cuticular Chitin Contributes to Form and Function.

  2020cites this paper
• Cloning, functional characterization and screening of potential inhibitors for Chilo partellus chitin synthase A using in silico, in vitro and in vivo approaches

  2020cites this paper
• Alleles in metabolic and oxygen‐sensing genes are associated with antagonistic pleiotropic effects on life history traits and population fitness in an ecological model insect *

  2020cites this paper
• Design, Synthesis, Acaricidal Activities, and Structure-Activity Relationship Studies of Novel Oxazolines Containing Sulfonate Moieties.

  2019cites this paper
• Transcriptional plasticity of different ABC transporter genes from Tribolium castaneum contributes to diflubenzuron resistance.

  2019cites this paper
• Chito-Protein Matrices in Arthropod Exoskeletons and Peritrophic Matrices

  2019cites this paper
• Peritrophic Matrix Formation.

  2019cites this paper
• Chapter 2 Chitin Metabolic Pathways in Insects and Their Regulation

  2019influential citation
• Chitin in Arthropods: Biosynthesis, Modification, and Metabolism.

  2019cites this paper
• Chitinous Structures as Potential Targets for Insect Pest Control.

  2019cites this paper
• Structure, Regulation, and Potential Applications of Insect Chitin-Metabolizing Enzymes

  2018cites this paper
• Identification of LmUAP1 as a 20‐hydroxyecdysone response gene in the chitin biosynthesis pathway from the migratory locust, Locusta migratoria

  2018cites this paper
• Enhancement of Bacillus thuringiensis Cry1Ac and Cry1Ca toxicity against Spodoptera exigua (Hübner) by suppression of a chitin synthase B gene in midgut

  2017cites this paper
• MicroRNA and dsRNA targeting chitin synthase A reveal a great potential for pest management of the hemipteran insect Nilaparvata lugens.

  2017cites this paper
• Excess trehalose and glucose affects chitin metabolism in brown planthopper (Nilaparvata lugens)

  2017cites this paper
• Down-regulation of a chitin synthase a gene by RNA interference enhances pathogenicity of Beauveria bassiana ANU1 against Spodoptera exigua (HÜBNER).

  2017cites this paper
• Characterization and RNAi-mediated knockdown of Chitin Synthase A in the potato tuber moth, Phthorimaea operculella

  2017cites this paper
• Identification and Functional Analysis of Chitin Synthase A in Oriental Armyworm, Mythimna separata

  2017cites this paper
• A chitinase from Euphorbia characias latex is a novel and powerful plant‐based pesticide against Drosophila suzukii

  2017cites this paper
• RNA interference of chitin synthase genes inhibits chitin biosynthesis and affects larval performance in Leptinotarsa decemlineata (Say)

  2016cites this paper
• Two Leptinotarsa uridine diphosphate N-acetylglucosamine pyrophosphorylases are specialized for chitin synthesis in larval epidermal cuticle and midgut peritrophic matrix.

  2016cites this paper
• Chitin Metabolic Pathways in Insects and Their Regulation

  2016influential citation
• GUT GENES ASSOCIATED WITH THE PERITROPHIC MATRIX IN Reticulitermes flavipes (Blattodea: Rhinotermitidae): IDENTIFICATION AND CHARACTERIZATION.

  2016cites this paper
• Biosynthesis, Turnover, and Functions of Chitin in Insects.

  2016cites this paper
• The Autographa californica multiple nucleopolyhedrovirus ac110 gene encodes a new per os infectivity factor.

  2016cites this paper
• Overview of chitin metabolism enzymes in Manduca sexta: Identification, domain organization, phylogenetic analysis and gene expression.

  2015cites this paper
• Engineered chloroplast dsRNA silences cytochrome p450 monooxygenase, V‐ATPase and chitin synthase genes in the insect gut and disrupts Helicoverpa armigera larval development and pupation

  2015cites this paper
• Unique synteny and alternate splicing of the chitin synthases in closely related heliothine moths.

  2015cites this paper
• Functional Specialization Among Members Of Knickkopf Family Of Proteins In Insect Cuticle Organization

  2014cites this paper
• Biological and Biochemical Characterization of a Tick Feeding Stimuli Responsive Amblyomma americanum Acidic Chitinase in Tick Feeding Physiology

  2014cites this paper
• Effects of chitin synthase double-stranded RNA on molting and oogenesis in the Chagas disease vector Rhodnius prolixus.

  2014cites this paper
• Exposure to Diflubenzuron Results in an Up-Regulation of a Chitin Synthase 1 Gene in Citrus Red Mite, Panonychus citri (Acari: Tetranychidae)

  2014cites this paper
• Dual silencing of long and short Amblyomma americanum acidic chitinase forms weakens the tick cement cone stability

  2014cites this paper
• cDNAs Encoding Chitin Synthase from Shrimp (Pandalopsis Japonica): Molecular Characterization and Expression Analysis

  2014influential citation
• Chitin synthesis inhibitors: old molecules and new developments

  2013influential citation
• Identification, mRNA Expression, and Functional Analysis of Chitin Synthase 1 Gene and Its Two Alternative Splicing Variants in Oriental Fruit Fly, Bactrocera dorsalis

  2013cites this paper
• Biochemical characterization of chitin synthase activity and inhibition in the African malaria mosquito, Anopheles gambiae

  2013influential citation
• A Lepidopteran-Specific Gene Family Encoding Valine-Rich Midgut Proteins

  2013cites this paper
• GENETIC VARIATION IN HIF SIGNALING UNDERLIES QUANTITATIVE VARIATION IN PHYSIOLOGICAL AND LIFE‐HISTORY TRAITS WITHIN LOWLAND BUTTERFLY POPULATIONS

  2013cites this paper
• Identification and characterization of two chitin synthase genes in African malaria mosquito, Anopheles gambiae.

  2012cites this paper
• Characterization of Novel Components of the Baculovirus Per Os Infectivity Factor Complex

  2012cites this paper
• Chitin Metabolism in Insects

  2012cites this paper
• Putative Chitin Synthases from Branchiostoma floridae Show Extracellular Matrix-related Domains and Mosaic Structures

  2012cites this paper
• Physiological significance of alternatively spliced exon combinations of the single‐copy gene class A chitin synthase in the insect Ostrinia furnacalis (Lepidoptera)

  2012influential citation
• Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species Tribolium castaneum.

  2012cites this paper
• Avaliação do efeito da seleção com inibidor de síntese de quitina e da exposição a doses parcialmente letais de inseticidas em populações de campo de Aedes aegypti

  2012cites this paper
• Cuticular chitin synthase and chitinase mRNA of whiteleg shrimp Litopenaeus vannamei during the molting cycle

  2012cites this paper
• Chitin-related enzymes in agro-biosciences.

  2012cites this paper
• Chitin synthase 1 gene and its two alternative splicing variants from two sap-sucking insects, Nilaparvata lugens and Laodelphax striatellus (Hemiptera: Delphacidae).

  2012cites this paper
• Avaliação do efeito da seleção com inibidor de síntese de quitina e da exposição a doses parcialmente letais de inseticidas em populações de campo de Aedes aegypti

  2012cites this paper
• 29. Chitin Synthesis

  2012cites this paper
• Both UDP N-acetylglucosamine pyrophosphorylases of Tribolium castaneum are critical for molting, survival and fecundity.

  2011cites this paper
• A novel alternative splicing site of class A chitin synthase from the insect Ostrinia furnacalis - gene organization, expression pattern and physiological significance.

  2011cites this paper
• The cellular basis of chitin synthesis in fungi and insects: common principles and differences.

  2011cites this paper
• An epidermis-specific chitin synthase CDNA in Choristoneura fumiferana: cloning, characterization, developmental and hormonal-regulated expression.

  2011cites this paper
• The molecular mechanisms of Knickkopf and Retroactive proteins in organization and protection of chitin in the newly synthesized insect exoskeleton

  2011cites this paper
• CHARACTERIZATION OF CHITIN SYNTHASE AND CHITINASE GENE FAMILIES FROM THE AFRICAN MALARIA MOSQUITO

  2010influential citation
• Proteolytic processing of fungal and insect proteins involved in chitin synthesis

  2010influential citation
• Cloning and expression pattern of chitin synthase ( CHS ) gene in epidermis of Ectropis obliqua Prout

  2010cites this paper
• Chitin Biochemistry: Synthesis, Hydrolysis and Inhibition

  2010cites this paper
• Effects of different corn silage: Alfalfa silage ratios and full fat extruded soybeans on milk composition, conjugated linoleic acids content in milk fat and performance of dairy cows

  2010cites this paper
• Silencing of two alternative splicing-derived mRNA variants of chitin synthase 1 gene by RNAi is lethal to the oriental migratory locust, Locusta migratoria manilensis (Meyen).

  2010cites this paper
• Different Functions of the Insect Soluble and Membrane-Bound Trehalase Genes in Chitin Biosynthesis Revealed by RNA Interference

  2010cites this paper
• Identification of 20-Hydroxyecdysone Late-Response Genes in the Chitin Biosynthesis Pathway

  2010cites this paper
• New insights into peritrophic matrix synthesis, architecture, and function.

  2009cites this paper
• Developmental Control of a Lepidopteran Pest Spodoptera exigua by Ingestion of Bacteria Expressing dsRNA of a Non-Midgut Gene

  2009cites this paper
• Yeast chitin synthase 2 activity is modulated by proteolysis and phosphorylation.

  2009cites this paper
• Purification of an active, oligomeric chitin synthase complex from the midgut of the tobacco hornworm.

  2009cites this paper
• Insecticidal action of mammalian galectin-1 against diamondback moth (Plutella xylostella).

  2009cites this paper
• Pós-Graduação em Biologia Celular e Molecular

  2009cites this paper
• The role of GlcNAc in formation and function of extracellular matrices.

  2008cites this paper
• Chapter 6 – Metabolic Systems

  2008cites this paper
• Molecular cloning, expression pattern and comparative analysis of chitin synthase gene B in Spodoptera exigua.

  2008cites this paper
• Functional specialization among insect chitinase family genes revealed by RNA interference

  2008cites this paper
• A chymotrypsin-like serine protease interacts with the chitin synthase from the midgut of the tobacco hornworm.

  2007cites this paper
• The class A chitin synthase gene of Spodoptera exigua: molecular cloning and expression patterns.

  2007cites this paper
• Developmental and tissue-specific expression of CHS1 from Plutella xylostella and its response to chlorfluazuron

  2007cites this paper
• A chymotrypsin-like serine protease interacts with the chitin synthase from the midgut of the tobacco hornworm

  2007cites this paper
• Regulatory mechanisms of chitin biosynthesis and roles of chitin in peritrophic matrix formation in the midgut of adult Aedes aegypti.

  2006influential citation
• Bioinformatic analysis of neuropeptide and receptor expression profiles during midgut metamorphosis in Drosophila melanogaster.

  2006cites this paper
• Characterization of a chitin synthase cDNA and its increased mRNA level associated with decreased chitin synthesis in Anopheles quadrimaculatus exposed to diflubenzuron.

  2006cites this paper
• CHITIN METABOLISM IN INSECTS: CHITIN SYNTHASES AND BETA-N-ACETYLGLUCOSAMINIDASES

  2006cites this paper
• Sequences of cDNAs and expression of genes encoding chitin synthase and chitinase in the midgut of Spodoptera frugiperda.

  2005cites this paper