Abstract Cancer treatments may compromise the fertility of children, adolescents, and young adults, and treatment-related infertility represents an important survivorship issue that should be addressed at diagnosis and in follow-up to ensure optimal decision-making, including consideration of pursuing fertility preservation. Risk of infertility varies substantially with patient and treatment factors. The ability to accurately assess fertility risk for many patients is hampered by limitations of the current literature, including heterogeneity in patient populations, treatments, and outcome measures. In this article, we review and synthesize the available data to estimate fertility risks from modern cancer treatments for both children and adult cancer survivors to enable clinicians to counsel patients about future fertility.
Cancer Treatment-Related Infertility: A Critical Review of the Evidence
P. Poorvu,A. L. Frazier,Angela M. Feraco,P. Manley,E. Ginsburg,M. Laufer,A. LaCasce,L. Diller,A. Partridge
Published 2019 in JNCI Cancer Spectrum
ABSTRACT
PUBLICATION RECORD
- Publication year
2019
- Venue
JNCI Cancer Spectrum
- Publication date
2019-03-01
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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