A novel protein modification generating an aldehyde group in sulfatases: its role in catalysis and disease

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Bioessays

• Publication date

  1998-06-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1002/(SICI)1521-1878(199806)20:6<505::AID-BIES9>3.0.CO;2-KPMID 9699462
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis.

  1998cited by this paper
• Sulfatases, Trapping of the Sulfated Enzyme Intermediate by Substituting the Active Site Formylglycine *

  1998cited by this paper
• Arylsulfatase from Klebsiella pneumoniae Carries a Formylglycine Generated from a Serine*

  1998cited by this paper
• Conversion of cysteine to formylglycine in eukaryotic sulfatases occurs by a common mechanism in the endoplasmic reticulum

  1998cited by this paper
• The sulfatase gene family.

  1997cited by this paper
• Conversion of cysteine to formylglycine: a protein modification in the endoplasmic reticulum.

  1997cited by this paper
• Identification by shotgun sequencing, genomic organization, and functional analysis of a fourth arylsulfatase gene (ARSF) from the Xp22.3 region.

  1997cited by this paper
• Structure of a human lysosomal sulfatase.

  1997cited by this paper
• Role of calcium in maintaining the heme environment of manganese peroxidase.

  1997cited by this paper
• Characterization of a cluster of sulfatase genes on Xp22.3 suggests gene duplications in an ancestral pseudoautosomal region.

  1996cited by this paper
• An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae.

  1996cited by this paper
• Molecular cloning and site-specific mutagenesis of a gene involved in arylsulfatase production in Campylobacter jejuni

  1996cited by this paper
• The evolutionary conservation of a novel protein modification, the conversion of cysteine to serinesemialdehyde in arylsulfatase from Volvox carteri.

  1996cited by this paper
• A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency.

  1995cited by this paper
• Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome

  1995cited by this paper
• Purification and characterization of the arylsulfatase synthesized by Pseudomonas aeruginosa PAO during growth in sulfate-free medium and cloning of the arylsulfatase gene (atsA).

  1995cited by this paper
• Arylsulphatase from Alteromonas carrageenovora.

  1995cited by this paper
• A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy.

  1995cited by this paper
• Late infantile metachromatic leukodystrophy in Israel.

  1994cited by this paper
• An inducible arylsulfatase of Volvox carteri with properties suitable for a reporter-gene system. Purification, characterization and molecular cloning.

  1994cited by this paper
• DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication.

  1993cited by this paper
• Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.

  1992cited by this paper
• Multiple sulfatase deficiency: catalytically inactive sulfatases are expressed from retrovirally introduced sulfatase cDNAs.

  1992cited by this paper
• Reaction mechanism of alkaline phosphatase based on crystal structures. Two-metal ion catalysis.

  1991cited by this paper
• A sulfur- and tyramine-regulated Klebsiella aerogenes operon containing the arylsulfatase (atsA) gene and the atsB gene

  1990cited by this paper

• New Insights into the Plutella xylostella Detoxifying Enzymes: Sequence Evolution, Structural Similarity, Functional Diversity, and Application Prospects of Glucosinolate Sulfatases

  2023cites this paper
• Bivalent EGFR-Targeting DARPin-MMAE Conjugates

  2022cites this paper
• Ancestral lysosomal enzymes with increased activity harbor therapeutic potential for treatment of Hunter syndrome

  2021cites this paper
• Protein Engineering Strategies for Improved Pharmacokinetics

  2021cites this paper
• Enzymatic bioconjugation to nanoparticles

  2021cites this paper
• Mucopolysaccharidosis type II (Hunter syndrome): Clinical and biochemical aspects of the disease and approaches to its diagnosis and treatment.

  2020cites this paper
• Bifunctional Reagents for Formylglycine Conjugation: Pitfalls and Breakthroughs

  2020cites this paper
• INVESTIGATION OF NATURAL KILLER CELL ACTIVITY, ANTIOXIDANT ENZYMES AND ARYLSULFATASE-A ACTIVITY IN THE HUMAN NEWBORN

  2019cites this paper
• Measurement of recombinant human arylsulfatase A and leukocyte sulfatase activities by analytical isotachophoresis.

  2019cites this paper
• Impaired redox regulation of estrogen metabolizing proteins is important determinant of human breast cancers

  2019cites this paper
• Transition State Interactions in a Promiscuous Enzyme: Sulfate and Phosphate Monoester Hydrolysis by Pseudomonas aeruginosa Arylsulfatase

  2018cites this paper
• Two-fold Bioorthogonal Derivatization by Different Formylglycine-Generating Enzymes.

  2018cites this paper
• Insights into Steroid Sulfation and Desulfation Pathways 1

  2018cites this paper
• A mini-review on the enzyme-mediated manipulation of proteins/peptides

  2018cites this paper
• Zweifach‐bioorthogonale Derivatisierung durch verschiedene Formylglycin‐generierende Enzyme

  2018cites this paper
• Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester

  2018cites this paper
• SULFATION PATHWAYS: Insights into steroid sulfation and desulfation pathways.

  2018cites this paper
• Activity of urine arylsulfatase A in brain‑dead graft donors is a predictor of early and late graft function.

  2017cites this paper
• Heterologous expression in Pichia pastoris and biochemical characterization of the unmodified sulfatase from Fusarium proliferatum LE1.

  2017cites this paper
• Ocular Manifestations of Inborn Errors of Metabolism

  2017cites this paper
• The Eye in Pediatric Systemic Disease

  2017cites this paper
• Heterologous expression in Pichia pastoris and biochemical characterization of the unmodified sulfatase from Fusarium proliferatum LE1

  2017cites this paper
• Assemblage par chimie click de fragments d’anticorps produits en bactéries pour un criblage fonctionnel rapide in vivo

  2016cites this paper
• The Regulation of Steroid Action by Sulfation and Desulfation

  2015cites this paper
• Eukaryotic formylglycine‐generating enzyme catalyses a monooxygenase type of reaction

  2015cites this paper
• Reconstitution of Formylglycine-generating Enzyme with Copper(II) for Aldehyde Tag Conversion

  2015cites this paper
• Characterization of a Recombinant Thermostable Arylsulfatase from Deep-Sea Bacterium Flammeovirga pacifica.

  2015cites this paper
• Formylglycine, a post-translationally generated residue with unique catalytic capabilities and biotechnology applications.

  2015cites this paper
• Further Characterization of Cys-Type and Ser-Type Anaerobic Sulfatase Maturating Enzymes Suggests a Commonality in Mechanism of Catalysis

  2014cites this paper
• Catalytic Zinc Complexes for Phosphate Diester Hydrolysis

  2014cites this paper
• Optomechanische Untersuchungen an Biomolekülen mittels Rastersondenmikroskopie

  2014influential citation
• Low-Scale expression and purification of an active putative iduronate 2-sulfate sulfatase-Like enzyme from Escherichia coli K12

  2013cites this paper
• Sulfatase inhibitors: a patent review

  2013cites this paper
• Further characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in the mechanism of catalysis.

  2013cites this paper
• An Italian Cohort Study Identifies Four New Pathologic Mutations in the ARSA Gene

  2013cites this paper
• Proprotein Convertases Process and Thereby Inactivate Formylglycine-generating Enzyme*

  2013cites this paper
• The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity

  2013cites this paper
• Site-specific chemical protein conjugation using genetically encoded aldehyde tags

  2012cites this paper
• Metabolic pathway engineering for hyaluronic acid production

  2012cites this paper
• The structure of human GALNS reveals the molecular basis for mucopolysaccharidosis IV A.

  2012cites this paper
• The activation of arylsulfatases

  2012cites this paper
• Heparin-Degrading Sulfatases in Hepatocellular Carcinoma: Potential roles in Pathogenesis and Identification of Therapeutic Targets

  2011cites this paper
• Bacterial Glycosyltransferases Involved in Molecular Mimicry of Mammalian Glycans

  2011cites this paper
• 8.09 – Phosphoryl and Sulfuryl Transfer

  2010cites this paper
• Human sulfatase transiently and functionally active expressed in E. coli K12

  2010cites this paper
• Model systems for primordial enzymes

  2010cites this paper
• Phosphoryl and Sulfuryl Transfer

  2010cites this paper
• Glucosamine‐6‐sulfamate Analogues of Heparan Sulfate as Inhibitors of Endosulfatases

  2010cites this paper
• “IDS crossing of the Blood-Brain Barrier corrects CNS defects in MPSII mice”

  2010cites this paper
• Reversible and Mechanism-Based Irreversible Inhibitor Studies on Human Steroid Sulfatase and Protein Tyrosine Phosphatase 1B

  2009cites this paper
• Effects of mutations and glycosylations on STS activity: a site-directed mutagenesis study.

  2008cites this paper
• In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters.

  2008cites this paper
• The Non-catalytic N-terminal Extension of Formylglycine-generating Enzyme Is Required for Its Biological Activity and Retention in the Endoplasmic Reticulum*

  2008cites this paper
• ERp44 Mediates a Thiol-independent Retention of Formylglycine-generating Enzyme in the Endoplasmic Reticulum*

  2008cites this paper
• Paralog of the formylglycine‐generating enzyme – retention in the endoplasmic reticulum by canonical and noncanonical signals

  2008cites this paper
• Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.

  2008cites this paper
• The heparanome--the enigma of encoding and decoding heparan sulfate sulfation.

  2007cites this paper
• Probing the oxygen-binding site of the human formylglycine-generating enzyme using halide ions.

  2007cites this paper
• CELLULAR MECHANISMS OF NEURODEGENERATION

  2006cites this paper
• Molecular Characterization of pFGE, the Paralog of the C-α-Formylglycine-generating Enzyme

  2006cites this paper
• Gene Trap Disruption of the Mouse Heparan Sulfate 6-O-Endosulfatase Gene, Sulf2

  2006cites this paper
• Boronic acids as inhibitors of steroid sulfatase.

  2006cites this paper
• Difficulty in Recognizing Multiple Sulfatase Deficiency in an Infant

  2006cites this paper
• Measuring the activities of the Sulfs: two novel heparin/heparan sulfate endosulfatases.

  2006cites this paper
• A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme.

  2006cites this paper
• Dificultades en el reconocimiento del déficit de sulfatasa múltiple en un lactante

  2006cites this paper
• Cathepsin D Deficiency - Molecular and Cellular Mechanisms of Neurodegeneration

  2006cites this paper
• Protein posttranslational modifications: the chemistry of proteome diversifications.

  2005cites this paper
• Purification and characterization of the recombinant arylsulfatase cloned from Pseudoalteromonas carrageenovora.

  2005cites this paper
• A fluorogenic substrate for the continuous assaying of aryl sulfatases.

  2005cites this paper
• Posttranslationale Proteinmodifikation: die Chemie der Proteomdiversifizierung

  2005cites this paper
• Transport of Lysosomal Enzymes

  2005cites this paper
• Analysis of normal and mutant iduronate-2-sulphatase conformation.

  2005cites this paper
• Expression, Localization, Structural, and Functional Characterization of pFGE, the Paralog of the Cα-Formylglycine-generating Enzyme*

  2005cites this paper
• Multiple sulfatase deficiency

  2005cites this paper
• Crystal Structure of Human pFGE, the Paralog of the Cα-formylglycine-generating Enzyme*

  2005cites this paper
• Molecular Characterization of the Human Cα-formylglycine-generating Enzyme*

  2005cites this paper
• Sulfatasen: Struktur, Mechanismus, biologische Aktivität, Inhibition, Anwendung in Synthesen

  2004cites this paper
• Post-translational generation of Cá-formylglycine in Prokaryotic Sulfatsases by Radical SAM-Proteins

  2004cites this paper
• Post-translational Formylglycine Modification of Bacterial Sulfatases by the Radical S-Adenosylmethionine Protein AtsB*

  2004cites this paper
• Metabolism of Sulphur-Containing Organic Compounds

  2004cites this paper
• Sulfotransferases: structure, mechanism, biological activity, inhibition, and synthetic utility.

  2004cites this paper
• Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility.

  2004cites this paper
• Overexpression of inactive arylsulphatase mutants and in vitro activation by light-dependent oxidation with vanadate.

  2004cites this paper
• Evidence for a post-translational modification, aspartyl aldehyde, in a photosynthetic membrane protein.

  2004cites this paper
• Posttranslational Modification of Serine to Formylglycine in Bacterial Sulfatases

  2003cites this paper
• Identification of formylglycine in sulfatases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  2003cites this paper
• Sulfur Cycle in Soils

  2003cites this paper
• The Heparin/Heparan Sulfate 2-O-Sulfatase from Flavobacterium heparinum

  2003cites this paper
• A major step on the road to understanding a unique posttranslational modification and its role in a genetic disease.

  2003cites this paper
• Arylsulfatases (Arylsulfate Sulfohydrolases)

  2002cites this paper
• Arylsulfatase-A in umbilical cord blood: gestational age and mode of delivery do not influence enzyme activity

  2002cites this paper
• Sulfatases (Sulfohydrolases, Sulfuric Ester Hydrolases)

  2002cites this paper
• Cysteine‐Modifying Enzyme (Sulfatase‐Modifying Enzyme)

  2002cites this paper
• Inherited Diseases of Intermediary Metabolism: Molecular Basis

  2001cites this paper
• Unusual Clinical Presentation in Two Cases of Multiple Sulfatase Deficiency

  2001cites this paper
• 7 Reaction mechanisms. Part (iii) Bioorganic enzyme-catalyzed reactions

  2001cites this paper
• 3 Å Structure of Arylsulfatase from Pseudomonas aeruginosa Establishes the Catalytic Mechanism of Sulfate Ester Cleavage in the Sulfatase

  2001cites this paper
• Characterization of Posttranslational Formylglycine Formation by Luminal Components of the Endoplasmic Reticulum*

  2001cites this paper
• 1.3 A structure of arylsulfatase from Pseudomonas aeruginosa establishes the catalytic mechanism of sulfate ester cleavage in the sulfatase family.

  2001cites this paper