Rab proteins of the endoplasmic reticulum: functions and interactors.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Biochemical Society Transactions

• Publication date

  2012-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1042/BST20120158PMID 23176493
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Where the endoplasmic reticulum and the mitochondrion tie the knot: the mitochondria-associated membrane (MAM).

  2013cited by this paper
• Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases

  2012cited by this paper
• Rab32 Is Important for Autophagy and Lipid Storage in Drosophila

  2012cited by this paper
• Illuminating the functional and structural repertoire of human TBC/RABGAPs

  2012cited by this paper
• BLOC-2, AP-3, and AP-1 Proteins Function in Concert with Rab38 and Rab32 Proteins to Mediate Protein Trafficking to Lysosome-related Organelles*

  2012cited by this paper
• Rab30 is required for the morphological integrity of the Golgi apparatus

  2012cited by this paper
• GTPase networks in membrane traffic.

  2012cited by this paper
• A role for mitochondria in NLRP3 inflammasome activation

  2011cited by this paper
• Urban planning of the endoplasmic reticulum (ER): How diverse mechanisms segregate the many functions of the ER

  2011cited by this paper
• The Role of Nogo and the Mitochondria–Endoplasmic Reticulum Unit in Pulmonary Hypertension

  2011cited by this paper
• Staying in touch: the molecular era of organelle contact sites.

  2011cited by this paper
• Reticulon 3 attenuates the clearance of cytosolic prion aggregates via inhibiting autophagy

  2011cited by this paper
• Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation

  2011cited by this paper
• Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

  2011cited by this paper
• ER Tubules Mark Sites of Mitochondrial Division

  2011cited by this paper
• DENN Domain Proteins: Regulators of Rab GTPases*

  2011cited by this paper
• Analysis of Rab GTPase-Activating Proteins Indicates that Rab1a/b and Rab43 Are Important for Herpes Simplex Virus 1 Secondary Envelopment

  2011cited by this paper
• Organelle structure and biogenesis

  2011cited by this paper
• Rab18 Dynamics in Adipocytes in Relation to Lipogenesis, Lipolysis and Obesity

  2011cited by this paper
• Quantitative Proteomic Analyses of Human Cytomegalovirus-Induced Restructuring of Endoplasmic Reticulum-Mitochondrial Contacts at Late Times of Infection*

  2011cited by this paper
• Weaving the web of ER tubules.

  2011cited by this paper
• Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase

  2011cited by this paper
• Role of Rab GTPases in membrane traffic and cell physiology.

  2011cited by this paper
• New links between vesicle coats and Rab-mediated vesicle targeting.

  2011cited by this paper
• Rab GEFs and GAPs.

  2010cited by this paper
• Further assembly required: construction and dynamics of the endoplasmic reticulum network

  2010cited by this paper
• Autophagosome Formation Depends on the Small GTPase Rab1 and Functional ER Exit Sites

  2010cited by this paper
• Rab32 Modulates Apoptosis Onset and Mitochondria-associated Membrane (MAM) Properties*

  2010cited by this paper
• Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM).

  2010cited by this paper
• Rab protein evolution and the history of the eukaryotic endomembrane system

  2010cited by this paper
• Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex

  2010cited by this paper
• PEX11 family members are membrane elongation factors that coordinate peroxisome proliferation and maintenance

  2010cited by this paper
• Rab33b and Rab6 are Functionally Overlapping Regulators of Golgi Homeostasis and Trafficking

  2010cited by this paper
• TRAPP complexes in membrane traffic: convergence through a common Rab

  2010cited by this paper
• Rab39a Binds Caspase-1 and Is Required for Caspase-1-dependent Interleukin-1β Secretion*

  2009cited by this paper
• Rab39a Binds Caspase-1 and Is Required for Caspase-1-dependent Interleukin-1β Secretion

  2009cited by this paper
• Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Glued and late endosome positioning

  2009cited by this paper
• A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions

  2009cited by this paper
• The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis.

  2008cited by this paper
• Direct link between Atg protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals

  2008cited by this paper
• Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation.

  2008cited by this paper
• Atlastin GTPases are required for Golgi apparatus and ER morphogenesis.

  2008cited by this paper
• Large Scale Screening for Novel Rab Effectors Reveals Unexpected Broad Rab Binding Specificity*S

  2008cited by this paper
• The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis

  2008cited by this paper
• Rab18 and Rab43 have key roles in ER-Golgi trafficking

  2008cited by this paper
• Giantin interacts with both the small GTPase Rab6 and Rab1.

  2007cited by this paper
• A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells.

  2007cited by this paper
• A role for Rab5 in structuring the endoplasmic reticulum

  2007cited by this paper
• Rab1b interacts with GBF1 and modulates both ARF1 dynamics and COPI association.

  2007cited by this paper
• Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells

  2007cited by this paper
• Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators

  2007cited by this paper
• Rabaptin-5-independent membrane targeting and Rab5 activation by Rabex-5 in the cell.

  2007cited by this paper
• Rab6 is increased in Alzheimer's disease brain and correlates with endoplasmic reticulum stress

  2007cited by this paper
• Rabs and their effectors: Achieving specificity in membrane traffic

  2006cited by this paper
• Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics

  2006cited by this paper
• TIP47 is a key effector for Rab9 localization

  2006cited by this paper
• Thematic review series: Lipid Posttranslational Modifications. Geranylgeranylation of Rab GTPases Published, JLR Papers in Press, January 9, 2006.

  2006cited by this paper
• Quantitative proteomics analysis of the secretory pathway.

  2006cited by this paper
• Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes

  2006cited by this paper
• α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models

  2006cited by this paper
• Rab6A and Rab6A′ GTPases Play Non‐overlapping Roles in Membrane Trafficking

  2006cited by this paper
• The multiple activities of CtBP/BARS proteins: the Golgi view.

  2006cited by this paper
• Recruitment of TIP47 to lipid droplets is controlled by the putative hydrophobic cleft.

  2006cited by this paper
• A class of membrane proteins shaping the tubular endoplasmic reticulum.

  2006cited by this paper
• Targeting of Rab GTPases to cellular membranes.

  2005cited by this paper
• Expression and characterization of Rab38, a new member of the Rab small G protein family

  2005cited by this paper
• A GTPase-activating protein controls Rab5 function in endocytic trafficking

  2005cited by this paper
• Biogenesis of tubular ER-to-Golgi transport intermediates.

  2005cited by this paper
• A Cryptic Rab1-binding Site in the p115 Tethering Protein*♦

  2005cited by this paper
• Rab18 localizes to lipid droplets and induces their close apposition to the endoplasmic reticulum-derived membrane

  2005cited by this paper
• Multiple regions contribute to membrane targeting of Rab GTPases

  2004cited by this paper
• Targeting Rab GTPases to distinct membrane compartments

  2004cited by this paper
• Rab escort protein 1 (REP1) in intracellular traffic: a functional and pathophysiological overview

  2004cited by this paper
• Membrane targeting of Rab GTPases is influenced by the prenylation motif.

  2003cited by this paper
• Dual prenylation is required for Rab protein localization and function.

  2003cited by this paper
• Yip3 catalyses the dissociation of endosomal Rab–GDI complexes

  2003cited by this paper
• Molecular cloning, bacterial expression and properties of Rab31 and Rab32.

  2002cited by this paper
• Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics

  2002cited by this paper
• Induction of Autophagy Causes Dramatic Changes in the Subcellular Distribution of GFP‐Rab24

  2002cited by this paper
• Yop1p, the Yeast Homolog of the Polyposis Locus Protein 1, Interacts with Yip1p and Negatively Regulates Cell Growth*

  2001cited by this paper
• Rab1 Interaction with a GM130 Effector Complex Regulates COPII Vesicle cis‐Golgi Tethering

  2001cited by this paper
• A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic

  2001cited by this paper
• Degradation of Endoplasmic Reticulum (ER) Quality Control Substrates Requires Transport between the ER and Golgi*

  2001cited by this paper
• PRA Isoforms Are Targeted to Distinct Membrane Compartments*

  2001cited by this paper
• Identification of rabaptin‐5, rabex‐5, and GM130 as putative effectors of rab33b, a regulator of retrograde traffic between the Golgi apparatus and ER

  2001cited by this paper
• Rab24 Is an Atypical Member of the Rab GTPase Family

  2000cited by this paper
• Rab2 Requires PKCι/Λ to Recruit β‐COP for Vesicle Formation

  2000cited by this paper
• Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion.

  2000cited by this paper
• Crystal structures of a Rab protein in its inactive and active conformations.

  2000cited by this paper
• Rab2 requires PKC iota/lambda to recruit beta-COP for vesicle formation.

  2000cited by this paper
• The road taken: past and future foundations of membrane traffic.

  2000cited by this paper
• Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum

  1999cited by this paper
• Molecular Role for the Rab Binding Platform of Guanine Nucleotide Dissociation Inhibitor in Endoplasmic Reticulum to Golgi Transport*

  1998cited by this paper
• A Rab GTPase Is Required for Homotypic Assembly of the Endoplasmic Reticulum*

  1997cited by this paper
• Rab2 Is Essential for the Maturation of Pre-Golgi Intermediates*

  1996cited by this paper
• Localization of the small GTP-binding protein rab1p to early compartments of the secretory pathway.

  1995cited by this paper
• Rab escort protein‐1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes.

  1994cited by this paper
• Rab1 and Ca2+ are required for the fusion of carrier vesicles mediating endoplasmic reticulum to Golgi transport

  1994cited by this paper
• Molecular cloning and characterization of two rab GDI species from rat brain: brain-specific and ubiquitous types.

  1994cited by this paper
• Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily.

  1993cited by this paper

• Contact-dependent incorporation of endoplasmic reticulum into retraction fibers and migrasomes.

  2025cites this paper
• Rab32-based vesicles coordinate mitochondria and actin for spindle migration and organelle rearrangement in oocyte meiosis

  2025cites this paper
• Rab32 protects mitochondrial function by anchoring Fancd2 and mediates the protective effect of penehyclidine hydrochloride against myocardial ischemia-reperfusion injury.

  2025cites this paper
• The host Rab9a/Rab32 axis is actively recruited to the Trypanosoma cruzi parasitophorous vacuole and benefits the infection cycle

  2024cites this paper
• Oxidative and Endoplasmic Reticulum Stress Represent Novel Therapeutic Targets for Choroideremia

  2023cites this paper
• Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS

  2023cites this paper
• Rab32 promotes glioblastoma migration and invasion via regulation of ERK/Drp1-mediated mitochondrial fission

  2023cites this paper
• Impact of interorganelle coordination between the conventional early secretory pathway and autophagy in cellular homeostasis and stress response

  2023cites this paper
• Exploitation of the host exocyst complex by bacterial pathogens

  2023cites this paper
• Dysregulation of the endoplasmic reticulum blocks recruitment of centrosome-associated proteins resulting in mitotic failure

  2023cites this paper
• Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy

  2023cites this paper
• Endosomal Rab GTPases regulate secretory granule maturation in Drosophila larval salivary glands

  2021cites this paper
• Golgi-associated Rab GTPases implicated in autophagy

  2021cites this paper
• CgRab1 regulates Cgcathepsin L1 expression and participates in the phagocytosis of haemocytes in oyster Crassostrea gigas.

  2021cites this paper
• Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins

  2021cites this paper
• Lipid droplet: A functionally active organelle in monocyte to macrophage differentiation and its inflammatory properties.

  2021cites this paper
• Phosphoproteomic Analysis as an Approach for Understanding Molecular Mechanisms of cAMP-Dependent Actions

  2021cites this paper
• Isoform-dependent subcellular localization of LMTK1A and LMTK1B, and their roles in axon outgrowth and spine formation.

  2020cites this paper
• Role of Armadillo repeat 2 and kinesin-II motor subunit Klp64D for wingless signaling in Drosophila

  2020cites this paper
• LMTK1, a Novel Modulator of Endosomal Trafficking in Neurons

  2020cites this paper
• The balance of protein farnesylation and geranylgeranylation during the progression of nonalcoholic fatty liver disease

  2020cites this paper
• Mitochondrial ALDH2 protects against lipopolysaccharide-induced myocardial contractile dysfunction by suppression of ER stress and autophagy.

  2019cites this paper
• ER-shaping Atlastin proteins act as central hubs to promote flavivirus replication and virion assembly

  2019cites this paper
• Restoration of Rab1 Levels Prevents Endoplasmic Reticulum Stress in Hippocampal Cells during Protein Aggregation Triggered by Rotenone.

  2019cites this paper
• The enigmatic ATP supply of the endoplasmic reticulum

  2018cites this paper
• Rab 10—a traffic controller in multiple cellular pathways and locations

  2018cites this paper
• Consequences of Rab GTPase dysfunction in genetic or acquired human diseases

  2018cites this paper
• Investigating proteins that regulate the architecture of the plant Endoplasmic Reticulum

  2018cites this paper
• Fluorescent sensors for the small GTPase switch

  2017cites this paper
• Critical importance of RAB proteins for synaptic function

  2017cites this paper
• PKN1 directs polarized RAB21 vesicle trafficking via phosphorylation of RPH3A and is important for neutrophil adhesion and ischemia-reperfusion injury

  2017cites this paper
• Rab32 connects ER stress to mitochondrial defects in multiple sclerosis

  2017cites this paper
• Protein Interactions in the Last Steps of the Endosomal Degradative Pathway

  2017cites this paper
• PKN1 Directs Polarized RAB21 Vesicle Trafficking via RPH3A and Is Important for Neutrophil Adhesion and Ischemia-Reperfusion Injury.

  2017cites this paper
• Identification of host factors required for Yersinia pestis macrophage intracellular survival and their impact on vacuole maturation, acidification and trafficking.

  2016cites this paper
• RAB GEFs exchange GTP for GDP on RABs

  2016cites this paper
• Rab proteins as regulators of lipid droplet formation and lipolysis

  2016cites this paper
• Regulatory Implications of Non-Trivial Splicing of Human Proteins

  2016cites this paper
• Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment.

  2016cites this paper
• The Role Of TKS5 SH3 Domains In Invadopodia Development And Activity

  2016cites this paper
• Ubiquitination independent of E1 and E2 enzymes by bacterial effectors

  2016cites this paper
• CSFV proliferation is associated with GBF1 and Rab2

  2016cites this paper
• Proteiny Rab, vnitrobuněčný transport

  2016cites this paper
• A high content screening microscopy approach to dissect the mechanism of Golgi-to-ER retrograde traffic

  2015cites this paper
• High-content analysis of Rab protein function at the ER-Golgi interface

  2015cites this paper
• Fluvastatin delays propagation of viral infection in isolated rat FDB myofibers but does not affect exocytic membrane trafficking

  2015cites this paper
• MS/MS‐based strategies for proteomic profiling of invasive cell structures

  2015cites this paper
• Lipid droplets and associated proteins in the skin: basic research and clinical perspectives

  2015cites this paper
• Unexpected Ancient Paralogs and an Evolutionary Model for the COPII Coat Complex

  2015cites this paper
• Regulation of mTORC1 by PI3K signaling.

  2015cites this paper
• A high-content screening microscopy approach to dissect the role of Rab proteins in Golgi-to-ER retrograde trafficking

  2015cites this paper
• Yersinia pestis Requires Host Rab1b for Survival in Macrophages

  2015cites this paper
• Membrane-Trafficking System Missing Pieces of an Ancient Puzzle : Evolution of the Eukaryotic

  2014cites this paper
• A global proteome approach in uric acid stimulated human aortic endothelial cells revealed regulation of multiple major cellular pathways.

  2014cites this paper
• Missing pieces of an ancient puzzle: evolution of the eukaryotic membrane-trafficking system.

  2014cites this paper
• Endoplasmic Reticulum Chaperones and Oxidoreductases: Critical Regulators of Tumor Cell Survival and Immunorecognition

  2014cites this paper
• Rab27A regulates exosome secretion from lung adenocarcinoma cells A549: involvement of EPI64

  2014cites this paper
• Interaction with the effector dynamin-related protein 1 (Drp1) is an ancient function of Rab32 subfamily proteins

  2014cites this paper
• The interplay between dynein, accessory proteins and the endocytic pathway

  2014cites this paper
• Untangling the web: mechanisms underlying ER network formation.

  2013influential citation
• RAB PROTEIN EXPRESSION REDUCES DIMER/OLIGOMER ALPHA-SYNUCLEIN AND FACILITATES DEGRADATION

  2013cites this paper
• Rab10 joins the ER social network

  2013cites this paper