A subset of memory CD4+ helper T lymphocytes identified by expression of Pgp-1

The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this observation extends to CD4+ T lymphocytes. Antigen-specific CD4+ T cells in mice immunized with sperm whale myoglobin or keyhole limpet hemocyanin were contained nearly exclusively in the minor Pgp-1+ subset.

• Publication year

  1989

• Venue

  Journal of Experimental Medicine

• Publication date

  1989-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/JEM.169.4.1461PMID 2564418PMCID 2189224
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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