Evaluation of p53 protein expression in Barrett's esophagus by two-parameter flow cytometry.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Gastroenterology

• Publication date

  1992-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0016-5085(92)90759-RPMID 1551529
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Barrett's esophagus and esophageal adenocarcinoma.

  1991cited by this paper
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• p53 mutations in human cancers.

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• Cancer surveillance in ulcerative colitis.

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• Rising incidence of adenocarcinoma of the esophagus and gastric cardia.

  1991cited by this paper
• Mutational hot spot in the p53 gene in human hepatocellular carcinomas

  1991cited by this paper
• The p53 tumour suppressor gene

  1991cited by this paper
• Genetic basis for p53 overexpression in human breast cancer.

  1991cited by this paper
• Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

  1991cited by this paper
• Endoscopic biopsy technique for acquiring larger mucosal samples.

  1991cited by this paper
• Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas.

  1991cited by this paper
• p53 expression in colorectal tumors.

  1991cited by this paper
• Mutational hotspot in the p53 gene in human hepatocellular carcinomas.

  1991cited by this paper
• p53 point mutation in HPV negative human cervical carcinoma cell lines.

  1991cited by this paper
• Activation of c-Ki-ras in human gastrointestinal dysplasias determined by direct sequencing of polymerase chain reaction products.

  1990cited by this paper
• Simultaneous monitoring of P53 protein and dna content of colorectal adenocarcinomas by flow cytometry

  1990cited by this paper
• p53: oncogene or anti-oncogene?

  1990cited by this paper
• Dominant oncogenes and tumor suppressor genes in the pathogenesis of lung cancer.

  1990cited by this paper
• p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.

  1990cited by this paper
• Tumor suppressor genes

  1990cited by this paper
• Mutant p53 DNA clones from human colon carcinomas cooperate with ras in transforming primary rat cells: a comparison of the "hot spot" mutant phenotypes.

  1990cited by this paper
• Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro

  1990cited by this paper
• Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines.

  1990cited by this paper
• Frequent mutation of the p53 gene in human esophageal cancer.

  1990cited by this paper
• Increased expression of mutant forms of p53 oncogene in primary lung cancer.

  1990cited by this paper
• Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.

  1990cited by this paper
• Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis.

  1990cited by this paper
• p53 mutations in colorectal cancer.

  1990cited by this paper
• Expression of the nuclear oncogene p53 in colon tumours

  1989cited by this paper
• Correlation of ultrastructural aberrations with dysplasia and flow cytometric abnormalities in Barrett's epithelium.

  1989cited by this paper
• Progression to cancer in Barrett's esophagus is associated with genomic instability.

  1989cited by this paper
• Chromosomal rearrangements in Barrett's esophagus. A premalignant lesion of esophageal adenocarcinoma.

  1989cited by this paper
• Adenocarcinoma arising in Barrett's esophagus

  1989cited by this paper
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  1989cited by this paper
• Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas.

  1989cited by this paper
• p53: a frequent target for genetic abnormalities in lung cancer.

  1989cited by this paper
• Mutations in the p53 gene occur in diverse human tumour types

  1989cited by this paper
• Observer variation in the diagnosis of dysplasia in Barrett's esophagus.

  1988cited by this paper
• Modified histogram subtraction technique for analysis of flow cytometry data.

  1988cited by this paper
• The Esophagus: Medical and Surgical Management

  1988cited by this paper
• Modified histogram subtraction technique for analysis of flow cytometry data

  1988cited by this paper
• Genetic alterations during colorectal-tumor development.

  1988cited by this paper
• Incidence of cancer of the esophagus in the US by histologic type

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• Endoscopic biopsy can detect high-grade dysplasia or early adenocarcinoma in Barrett's esophagus without grossly recognizable neoplastic lesions.

  1988cited by this paper
• Value of endoscopic surveillance in the detection of neoplastic change in Barrett's oesophagus

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  1987cited by this paper
• Barrett's esophagus. Correlation between flow cytometry and histology in detection of patients at risk for adenocarcinoma.

  1987cited by this paper
• The gene for human p53 cellular tumor antigen is located on chromosome 17 short arm (17p13).

  1986cited by this paper
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  1986cited by this paper
• Localization of gene for human p53 tumour antigen to band 17p13

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• Adenocarcinoma and Barrett's esophagus. An overrated risk?

  1984cited by this paper
• Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

  1984cited by this paper
• Barrett's Esophagus: Comparison of Benign and Malignant Cases

  1983cited by this paper
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  1983cited by this paper
• Barrett's esophagus: a review.

  1983cited by this paper
• T antigen is bound to a host protein in SY40-transformed cells

  1979cited by this paper

• Aberrant p53 expression is associated with neoplastic progression in Barrett oesophagus diagnosed as indefinite for dysplasia

  2022cites this paper
• K-means quantization for a web-based open-source flow cytometry analysis platform

  2021cites this paper
• Freecyto: Quantized Flow Cytometry Analysis for the Web

  2020cites this paper
• Histological assessment & use of immunohistochemical markers for detection of dysplasia in Barrett's esophageal mucosa.

  2018cites this paper
• Title Gene amplification of ERBB 2 and EGFR in adenocarcinoma in situ andintramucosal adenocarcinoma of Barrett ' s esophagus

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• Metaplasia and Dysplasia in Barrett’s Esophagus

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• 52. Barrett Esophagus and Esophageal Adenocarcinoma

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• Barrett esophagus: diagnostic challenges.

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• Risk factors associated with Barrett's epithelial dysplasia.

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• Evaluation of a 4‐protein serum biomarker panel—biglycan, annexin‐A6, myeloperoxidase, and protein S100‐A9 (B‐AMP)—for the detection of esophageal adenocarcinoma

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• Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastroesophageal junction

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• Molecular Pathology of Barrett’s Metaplasia and Esophageal Adenocarcinoma

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• Impact of tumor progression on cancer incidence curves.

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• Gastroesophageal Reflux Disease: Molecular Predictors in Neoplastic Progression of Barrett's Esophagus

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• Biology of Barrett's esophagus and esophageal adenocarcinoma.

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• Chapter 14 – Immunohistology of the Gastrointestinal Tract

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• The C. elegans p53 Family Gene cep-1 and The Nondisjunction Gene him-5 Are Required for Meiotic Recombination

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• Genesis of Barrett’s Neoplasia: Current Concepts

  2010cites this paper
• Gene amplification of ERBB2 and EGFR in adenocarcinoma in situ and intramucosal adenocarcinoma of Barrett's esophagus

  2010cites this paper
• Predicting Neoplastic Progression in Barrett's Esophagus.

  2010cites this paper
• Barrett esophagus and esophageal adenocarcinoma

  2009cites this paper
• Update on the diagnosis and treatment of Barrett esophagus and related neoplastic precursor lesions.

  2009cites this paper
• P53 and Ki-67 overexpression in gastroesophageal reflux disease--Barrett's esophagus and adenocarcinoma sequence.

  2009cites this paper
• Increased p53 Expression in the Malignant Transformation of Barrett’s Esophagus is Accompanied by an Upward Shift of the Proliferative Compartment

  2009cites this paper
• Immunohistochemical evaluation of a panel of tumor cell markers during malignant progression in Barrett esophagus.

  2008cites this paper
• Aneuploidy and high expression of p53 and Ki67 is associated with neoplastic progression in Barrett esophagus

  2008cites this paper
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  2007cites this paper
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  2007cites this paper
• Biomarkers for Risk Stratification of Neoplastic Progression in Barrett Esophagus

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  2007cites this paper
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  2006cites this paper
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• Clinical Use of p 53 in Barrett ’ s Esophagus

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  2006cites this paper
• Immunohistochemical evaluation of pRb2/p130, VEGF, EZH2, p53, p16, p21waf‐1, p27, and PCNA in Barrett's esophagus

  2006cites this paper
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  2006cites this paper
• Identification of clinically-informative biomarkers within the spectrum of gastro-oesophageal reflux disease in the South African population

  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2005cites this paper
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  2005cites this paper
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  2003cites this paper
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  2003cites this paper
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• El esófago de Barrett: la realidad biológica de una metaplasia columnar premaligna

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  2002cites this paper
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• Ösophaguskarzinom 1,2

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• Updated guidelines for the diagnosis, surveillance, and therapy of Barrett's esophagus

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• Review article: a conceptual approach to understanding the molecular mechanisms of cancer development in Barrett’s oesophagus

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• REVIEW: Barrett's Esophagus

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• Esophagogastric adenocarcinoma in an E1A/E1B transgenic model involves p53 disruption

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• p 53 Mutational Status Improves Estimation of Prognosis in Patients with Curatively Resected Adenocarcinoma in Barrett ’ s Esophagus 1

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• Analysis of Ki-67, p53 and Bcl-2 expression in the dysplasia-carcinoma sequence of Barrett's esophagus.

  1999cites this paper
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  1999cites this paper
• Overexpression of p53 protein associates decreased response to chemoradiotherapy in patients with esophageal carcinoma.

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• Expression of the cyclin‐dependent kinase inhibitor p21WAF1/CIP1 and p53 tumor suppressor in dysplastic progression and adenocarcinoma in Barrett esophagus

  1999influential citation
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