How do risk factors work together? Mediators, moderators, and independent, overlapping, and proxy risk factors.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  American Journal of Psychiatry

• Publication date

  2001-06-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1176/APPI.AJP.158.6.848PMID 11384888
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1996cited by this paper
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• The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations.

  1986influential reference
• The Robustness of Common Measures of 2×2 Association to Bias Due to Misclassifications

  1985cited by this paper
• Statistics and Causal Inference

  1985cited by this paper
• From Association to Causation in Observational Studies: The Role of Tests of Strongly Ignorable Treatment Assignment

  1984cited by this paper
• The Cost of Dichotomization

  1983cited by this paper
• Causal Models and Logical Inference in Epidemiological Psychiatry

  1980cited by this paper
• Effects of misclassifications on statistical inferences in epidemiology.

  1980cited by this paper
• Bias due to misclassification in the estimation of relative risk.

  1977cited by this paper
• The Effects of Misclassification on the Bias in the Difference Between Two Proportions and the Relative Odds in the Fourfold Table

  1975cited by this paper
• Genetic aspects of intelligence.

  1975cited by this paper
• Annotation: the analysis of variance and the analysis of causes.

  1974cited by this paper
• Estimating causal effects of treatments in randomized and nonrandomized studies.

  1974cited by this paper
• [Modern epidemiology].

  1971cited by this paper
• The Biochemical Basis of Neuropharmacology

  1971cited by this paper
• Effects of misclassification in epidemiologic studies.

  1968cited by this paper
• Effects of errors in classification and diagnosis in various types of epidemiological-studies.

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