The long non-coding RNA Fendrr links epigenetic control mechanisms to gene regulatory networks in mammalian embryogenesis

No abstract is available for this paper.

• Publication year

  2013

• Venue

  RNA Biology

• Publication date

  2013-08-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4161/rna.26165PMID 24036695PMCID PMC3866236
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Small noncoding differentially methylated copy-number variants, including lncRNA genes, cause a lethal lung developmental disorder

  2013cited by this paper
• The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus.

  2013cited by this paper
• The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.

  2013cited by this paper
• Ribosome profiling provides evidence that large noncoding RNAs do not encode proteins.

  2013cited by this paper
• Braveheart, a long noncoding RNA required for cardiovascular lineage commitment.

  2013cited by this paper
• Long noncoding RNAs regulate adipogenesis

  2013cited by this paper
• Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells

  2013cited by this paper
• Landscape of transcription in human cells

  2012cited by this paper
• Genome regulation by long noncoding RNAs.

  2012cited by this paper
• Triplexator: Detecting nucleic acid triple helices in genomic and transcriptomic data

  2012cited by this paper
• The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

  2012cited by this paper
• Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development

  2012cited by this paper
• Epigenetic Regulation by Long Noncoding RNAs

  2012cited by this paper
• Control of somatic tissue differentiation by the long non-coding RNA TINCR

  2012cited by this paper
• The noncoding RNA Mistral activates Hoxa6 and Hoxa7 expression and stem cell differentiation by recruiting MLL1 to chromatin.

  2011cited by this paper
• lincRNAs act in the circuitry controlling pluripotency and differentiation

  2011cited by this paper
• Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution.

  2011cited by this paper
• Advanced Protocols for Animal Transgenesis

  2011cited by this paper
• A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

  2011cited by this paper
• Tetraploid Complementation Assay

  2011cited by this paper
• Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions.

  2011cited by this paper
• Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes.

  2011cited by this paper
• Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses.

  2011cited by this paper
• Genome-wide identification of polycomb-associated RNAs by RIP-seq.

  2010cited by this paper
• Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

  2010influential reference
• The language of histone crosstalk.

  2010cited by this paper
• An inducible RNA interference system for the functional dissection of mouse embryogenesis

  2010cited by this paper
• Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

  2009cited by this paper
• Genomic and Genic Deletions of the FOX Gene Cluster on 16q24.1 and Inactivating Mutations of FOXF1 Cause Alveolar Capillary Dysplasia and Other Malformations

  2009cited by this paper
• Two mammalian MOF complexes regulate transcription activation by distinct mechanisms.

  2009cited by this paper
• The Tale of Two Domains

  2008cited by this paper
• Human ATAC Is a GCN5/PCAF-containing Acetylase Complex with a Novel NC2-like Histone Fold Module That Interacts with the TATA-binding Protein*

  2008cited by this paper
• Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

  2008cited by this paper
• Mammalian ASH1L Is a Histone Methyltransferase That Occupies the Transcribed Region of Active Genes

  2007cited by this paper
• Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs.

  2007cited by this paper
• Correction for Tan et al., SmyD1, a histone methyltransferase, is required for myofibril organization and muscle contraction in zebrafish embryos

  2006cited by this paper
• SmyD1, a histone methyltransferase, is required for myofibril organization and muscle contraction in zebrafish embryos

  2006cited by this paper
• SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

  2004cited by this paper
• MicroRNAs Modulate Hematopoietic Lineage Differentiation

  2004cited by this paper
• Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration

  2003cited by this paper
• An Extensive Class of Small RNAs in Caenorhabditis elegans

  2001cited by this paper
• Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.

  2001cited by this paper
• The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm.

  2001cited by this paper
• Investigation of Elements Sufficient To Imprint the Mouse Air Promoter

  2001cited by this paper
• Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations.

  2001cited by this paper
• Self-assembly of mesoscopically ordered chromatic polydiacetylene/silica nanocomposites

  2001cited by this paper
• The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

  2000cited by this paper
• Z/AP, a double reporter for cre-mediated recombination.

  1999cited by this paper
• Igf2 imprinting does not require its own DNA methylation or H19 RNA.

  1998cited by this paper
• The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14.

  1993cited by this paper
• The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus.

  1992cited by this paper
• The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus.

  1992cited by this paper
• Specificity of the three-stranded complex formation between double-stranded DNA and single-stranded RNA containing repeating nucleotide sequences.

  1968cited by this paper
• Edinburgh Research Explorer Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome

  year unknowncited by this paper

• Machine Learning Approaches for Predicting RNA-RNA/DNA Interactions.

  2026cites this paper
• Biomolecules Interacting with Long Noncoding RNAs

  2025cites this paper
• The relevance of RNA–DNA interactions as regulators of physiological functions

  2025cites this paper
• Using Deep Learning with Different Architectures to Recognize RNA:DNA Triplex Structures from Histone Modification Features

  2025cites this paper
• Single-Nucleotide Polymorphisms, PITX2 and Abnormal Electrical Activity in Atrial Fibrillation

  2025cites this paper
• Integration of HiMoRNA and RNAChrom: Validation of the Functional Role of Long Non-coding RNAs in the Epigenetic Regulation of Human Genes Using RNA-Chromatin Interactome Data

  2025cites this paper
• LncRNA FENDRR Inhibits Mitochondrial Apoptosis via TET2-Mediated DNA Demethylation of MFN1 in NSCPO.

  2025cites this paper
• Unlocking the therapeutic potential of lncRNA FENDRR in DCM: novel targets and insights via the miR-296-5p/HMGA1 axis

  2025cites this paper
• LncRNAs Regulate Vasculogenic Mimicry in Human Cancers

  2025cites this paper
• RNA-DNA triplexes: molecular mechanisms and functional relevance.

  2024cites this paper
• HiMoRNA and RNA-Chrom integration: Chromatin-Associated LncRNAs in Genome-Wide Epigenetic Regulation

  2024cites this paper
• Natural antisense transcripts as versatile regulators of gene expression

  2024cites this paper
• Disease-IncRNA associations prediction based on fast random walk with restart in heterogeneous networks

  2024cites this paper
• Coordinated regulation by lncRNAs results in tight lncRNA-target couplings

  2024cites this paper
• Transcription regulation by long non-coding RNAs: mechanisms and disease relevance

  2024cites this paper
• Biophysical Investigation of RNA ⋅ DNA : DNA Triple Helix and RNA : DNA Heteroduplex Formation by the lncRNAs MEG3 and Fendrr

  2024cites this paper
• Genome-wide transcriptome analysis reveals the diversity and function of long non-coding RNAs in dinoflagellates

  2023cites this paper
• Noncoding RNAs as Key Regulators for Cardiac Development and Cardiovascular Diseases

  2023cites this paper
• A hybrid approach to assess the structural impact of long noncoding RNA mutations uncovers key NEAT1 interactions in colorectal cancer

  2023cites this paper
• Epigenetics, cryptorchidism, and infertility

  2023cites this paper
• An HGF‐dependent positive feedback loop between bladder cancer cells and fibroblasts mediates lymphangiogenesis and lymphatic metastasis

  2023cites this paper
• Recent Development in Biomedical Applications of Oligonucleotides with Triplex-Forming Ability

  2023cites this paper
• Identification of Long Noncoding RNAs That Exert Transcriptional Regulation by Forming RNA–DNA Triplexes in Prostate Cancer

  2023cites this paper
• The Idiopathic Pulmonary Fibrosis-Associated Single Nucleotide Polymorphism RS35705950 Is Transcribed in a MUC5B Promoter Associated Long Non-Coding RNA (AC061979.1)

  2022cites this paper
• H19 inhibition increases HDAC6 and regulates IRS1 levels and insulin signaling in the skeletal muscle during diabetes

  2022cites this paper
• A single natural RNA modification can destabilize a U•A-T-rich RNA•DNA-DNA triple helix

  2022cites this paper
• Association of the Genetic Variation in the Long Non-Coding RNA FENDRR with the Risk of Developing Hypertrophic Cardiomyopathy

  2022cites this paper
• The emerging role of LncRNA FENDRR in multiple cancer: A review study.

  2022cites this paper
• Predictive urinary RNA biomarkers of kidney injury after extracorporeal shock wave lithotripsy

  2022cites this paper
• LncRNAs and Cardiovascular Disease.

  2022cites this paper
• Role of Nuclear Non-Canonical Nucleic Acid Structures in Organismal Development and Adaptation to Stress Conditions

  2022cites this paper
• HiMoRNA: A Comprehensive Database of Human lncRNAs Involved in Genome-Wide Epigenetic Regulation

  2022cites this paper
• Genomic and functional conservation of lncRNAs: lessons from flies

  2022cites this paper
• Splice variants denote differences between a cancer stem cell side population of EWSR1-ERG-based Ewing sarcoma cells, its main population and EWSR1-FLI-based cells

  2022cites this paper
• An HGF-dependent positive feedback loop between bladder cancer cells and �broblasts mediates lymphangiogenesis and lymphatic metastasis

  2022cites this paper
• Annelids win again: the first evidence of Hox antisense transcription in Spiralia

  2021cites this paper
• The Role of Epigenetics in Congenital Heart Disease

  2021cites this paper
• RNA editing regulates lncRNA splicing in human early embryo development

  2021cites this paper
• Fendrr synergizes with Wnt signalling to regulate fibrosis related genes during lung development via its RNA:dsDNA triplex element

  2021cites this paper
• Long non-coding RNA FENDRR inhibits the stemenss of colorectal cancer cells through directly binding to Sox2 RNA

  2021cites this paper
• HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex

  2021cites this paper
• Regulation of Sox8 through lncRNA Mrhl-Mediated Chromatin Looping in Mouse Spermatogonia

  2021cites this paper
• Prognostic and Predicted Significance of FENDRR in Colon and Rectum Adenocarcinoma

  2021cites this paper
• Long Noncoding RNA FENDRR Inhibits Lung Fibroblast Proliferation via a Reduction of β-Catenin

  2021cites this paper
• Illuminating lncRNA Function Through Target Prediction.

  2021cites this paper
• CRISPR/Cas9-mediated gene editing on Sox2ot promoter leads to its truncated expression and does not influence neural tube closure and embryonic development in mice.

  2021cites this paper
• More than causing (epi)genomic instability: emerging physiological implications of transposable element modulation

  2021cites this paper
• Epigenetics, Noncoding RNAs, and Gene Expression

  2021cites this paper
• ABHD4-Regulating RNA Panel: Novel Biomarkers in Acute Coronary Syndrome Diagnosis

  2021cites this paper
• LncRNA FENDRR Expression Correlates with Tumor Immunogenicity

  2021cites this paper
• LncRNA:DNA triplex-forming sites are positioned at specific areas of genome organization and are predictors for Topologically Associated Domains

  2021cites this paper
• Biogenesis and Modes of Action of miRs and Circular and Long Non-coding RNAs

  2021cites this paper
• Long noncoding RNAs and circular RNAs as heart failure biomarkers

  2021cites this paper
• Long Noncoding RNA lnc-TSSK2-8 Activates Canonical Wnt/β-Catenin Signaling Through Small Heat Shock Proteins HSPA6 and CRYAB

  2021cites this paper
• Crosslinker-modified nucleic acid probes for improved target identification and biomarker detection

  2021cites this paper
• Long Non-Coding RNAs in Insects

  2021cites this paper
• miRNAs and lncRNAs as Novel Therapeutic Targets to Improve Cancer Immunotherapy

  2021cites this paper
• The biological function and potential mechanism of long non‐coding RNAs in cardiovascular disease

  2020cites this paper
• Genetic and molecular determinants of prostate cancer among Iranian patients: An update

  2020cites this paper
• lncRNA RPL34‐AS1 inhibits cell proliferation and invasion while promoting apoptosis by competitively binding miR‐3663‐3p/RGS4 in papillary thyroid cancer

  2020cites this paper
• Long Noncoding RNAs: Molecular Modalities to Organismal Functions.

  2020cites this paper
• Cancer Susceptibility Candidate 9 (CASC9): A Novel Targetable Long Noncoding RNA in Cancer Treatment

  2020cites this paper
• Long Non-Coding RNAs in Biliary Tract Cancer—An Up-to-Date Review

  2020cites this paper
• Hypoxia and transforming growth factor β1 regulation of long non‐coding RNA transcriptomes in human pulmonary fibroblasts

  2020cites this paper
• Fendrr involves in the pathogenesis of cardiac fibrosis via regulating miR-106b/SMAD3 axis.

  2020cites this paper
• Practical Guidance in Genome-Wide RNA:DNA Triple Helix Prediction

  2020cites this paper
• Human Long Noncoding RNA Interactome: Detection, Characterization and Function

  2020cites this paper
• lncRNA-PLACT1 sustains activation of NF-κB pathway through a positive feedback loop with IκBα/E2F1 axis in pancreatic cancer

  2020cites this paper
• Seq’ing identity and function in a repeat-derived noncoding RNA world

  2020cites this paper
• LncRNA Functions as a New Emerging Epigenetic Factor in Determining the Fate of Stem Cells

  2020cites this paper
• The lncRNA Toolkit: Databases and In Silico Tools for lncRNA Analysis

  2020cites this paper
• RNA matchmaking in chromatin regulation.

  2020cites this paper
• Deep learning based DNA:RNA triplex forming potential prediction

  2020cites this paper
• Five lncRNAs Associated With Prostate Cancer Prognosis Identified by Coexpression Network Analysis

  2020cites this paper
• Long non coding RNA NRON inhibited breast cancer development through regulating miR-302b/SRSF2 axis.

  2020cites this paper
• Long non-coding RNA FENDRR regulates IFNγ-induced M1 phenotype in macrophages

  2020cites this paper
• Multi-omics annotation of human long non-coding RNAs.

  2020cites this paper
• Long non-coding RNAs (lncRNAs) and cardiovascular disease (CVD)

  2019cites this paper
• Prediction of lncRNAs and their interactions with nucleic acids: benchmarking bioinformatics tools

  2019cites this paper
• Long non-coding RNA POLR2E gene polymorphisms increased the risk of prostate cancer in a sample of the Iranian population

  2019cites this paper
• Long non-coding RNA FENDRR inhibits proliferation and invasion of hepatocellular carcinoma by down-regulating glypican-3 expression.

  2019cites this paper
• LncRNA NRON alleviates atrial fibrosis via promoting NFATc3 phosphorylation

  2019cites this paper
• Cardiovascular Risk Factors and Markers

  2019cites this paper
• The Role of Long Noncoding RNAs in Gene Expression Regulation

  2019cites this paper
• The Role of Non-Coding RNA in Congenital Heart Diseases

  2019cites this paper
• lncRedibly versatile: biochemical and biological functions of long noncoding RNAs.

  2019cites this paper
• Long non‐coding RNA FENDRR attenuates the stemness of non‐small cell lung cancer cells via decreasing multidrug resistance gene 1 (MDR1) expression through competitively binding with RNA binding protein HuR

  2019cites this paper
• Alveolar capillary dysplasia with misalignment of the pulmonary veins and hypoplastic left heart sequence caused by an in frame deletion within FOXF1

  2019cites this paper
• Long non-coding RNA: Classification, biogenesis and functions in blood cells.

  2019cites this paper
• Involvement of lncRNA-mediated signaling pathway in the development of cervical cancer.

  2019cites this paper
• Noncoding RNAs as Regulators of Gene Expression in Pluripotency and Differentiation

  2019cites this paper
• Stability of an RNA•DNA–DNA triple helix depends on base triplet composition and length of the RNA third strand

  2019cites this paper
• The importance of long non-coding RNAs in neuropsychiatric disorders.

  2019cites this paper
• Long non-coding RNA FOXF1 adjacent non-coding developmental regulatory RNA inhibits growth and chemotherapy resistance in non-small cell lung cancer

  2019cites this paper
• The role of long noncoding RNA in major human disease.

  2019cites this paper
• Exosomal long noncoding RNA LNMAT2 promotes lymphatic metastasis in bladder cancer.

  2019cites this paper
• lncRNA FENDRR Exhibits Anti-Fibrotic Activity in Pulmonary Fibrosis.

  2019cites this paper
• Diverging RNPs: Toward Understanding lncRNA-Protein Interactions and Functions.

  2019cites this paper
• The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis

  2019cites this paper
• Conserved Epigenetic Regulatory Logic Infers Genes Governing Cell Identity

  2019cites this paper