Generic phase diagram of active polar films.

We study theoretically the phase diagram of compressible active polar gels such as the actin network of eukaryotic cells. Using generalized hydrodynamics equations, we perform a linear stability analysis of the uniform states in the case of an infinite bidimensional active gel to obtain the dynamic phase diagram of active polar films. We predict, in particular, modulated flowing phases and a macroscopic phase separation at high activity. This qualitatively accounts for experimental observations of various active systems, such as actomyosin gels, microtubules and kinesins in vitro solutions, or swimming bacterial colonies.

• Publication year

  2006

• Venue

  Physical Review Letters

• Publication date

  2006-01-17

• Fields of study

  Materials Science, Medicine, Physics

• Identifiers
  DOI 10.1103/PhysRevLett.96.028102arXiv 0807.0275PMID 16486647
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Spontaneous flow transition in active polar gels

  2005cited by this paper
• Self-concentration and large-scale coherence in bacterial dynamics.

  2004cited by this paper
• Asters, vortices, and rotating spirals in active gels of polar filaments.

  2004cited by this paper
• Generic theory of active polar gels: a paradigm for cytoskeletal dynamics

  2004cited by this paper
• Internal motility in stiffening actin-myosin networks.

  2003cited by this paper
• Instabilities of isotropic solutions of active polar filaments.

  2003cited by this paper
• Self-organized patterns in mixtures of microtubules and motor proteins

  2003cited by this paper
• Rheology of active-particle suspensions.

  2003cited by this paper
• Self-organized pattern formation in motor-microtubule mixtures.

  2003cited by this paper
• Mechanics of Motor Proteins and the Cytoskeleton

  2002cited by this paper
• Self-propagating patterns in active filament bundles.

  2001cited by this paper
• Macroscopic equations for pattern formation in mixtures of microtubules and molecular motors.

  2001cited by this paper
• Mechanics of Motor Proteins and the Cytoskeleton

  2001cited by this paper
• Hydrodynamic fluctuations and instabilities in ordered suspensions of self-propelled particles.

  2001cited by this paper
• Actively contracting bundles of polar filaments.

  2000cited by this paper
• Self-organization of microtubules and motors

  1997cited by this paper
• Heavy meromyosin induces sliding movements between antiparallel actin filaments.

  1991cited by this paper
• Molecular Biology of the Cell

  1990cited by this paper
• Experimental results on a gas-loaded, free-electron laser.

  1988cited by this paper
• Theory of phase transitions and modulated structures in ferroelectrics.

  1985cited by this paper
• The physics of liquid crystals

  1974cited by this paper
• We are grateful.

  1971cited by this paper
• Superprecipitation of actomyosin reconstructed with F-actin and NEM-modified myosin.

  1966cited by this paper

• Activity drives self-assembly of passive soft inclusions in active nematics.

  2025cites this paper
• Stability of co-annular active and passive confined fluids

  2025cites this paper
• Statistical physics of active matter, cell division and cell aggregation

  2023cites this paper
• Onsager’s variational principle in proliferating biological tissues, in presence of activity and anisotropy

  2023cites this paper
• Density-Polarity Coupling in Confined Active Polar Films: Asters, Spirals, and Biphasic Orientational Phases.

  2023cites this paper
• Deforming polar active matter in a scalar field gradient

  2022cites this paper
• The analytical solution to the migration of an epithelial monolayer with a circular spreading front and its implications in the gap closure process

  2022cites this paper
• Active turbulence and spontaneous phase separation in inhomogeneous extensile active gels.

  2022cites this paper
• Active viscoelastic nematics with partial degree of order

  2022cites this paper
• Active nematic gel with quenched disorder.

  2022cites this paper
• Active-gel theory for multicellular migration of polar cells in the extra-cellular matrix

  2022cites this paper
• Thermodynamically consistent coarse-graining of polar active fluids

  2022cites this paper
• Symmetry-restoring crossover from defect-free to defect-laden turbulence in polar active matter

  2022cites this paper
• Helical flow states in active nematics.

  2021cites this paper
• A theoretical model for studying the nonlinear viscoelastic response of an active fluid undergoing oscillatory shear

  2021cites this paper
• Chiral Active Hexatics: Giant Number Fluctuations, Waves, and Destruction of Order.

  2020cites this paper
• Theory and Lattice Boltzmann simulation of active fluids

  2019cites this paper
• Thin-film modelling of complex fluids and bacterial colonies

  2019cites this paper
• Thin-film modeling of resting and moving active droplets.

  2019cites this paper
• Supracellular migration – beyond collective cell migration

  2019cites this paper
• Interfacial instabilities in active viscous films

  2019cites this paper
• Shape Transformations of Vesicles Induced by Swim Pressure.

  2019cites this paper
• The matrix environmental and cell mechanical properties regulate cell migration and contribute to the invasive phenotype of cancer cells

  2019cites this paper
• Supracellular contraction at the rear of neural crest cell groups drives collective chemotaxis

  2018cites this paper
• Active Suspensions have Nonmonotonic Flow Curves and Multiple Mechanical Equilibria.

  2018cites this paper
• The Effects of the Interplay between Motor and Brownian Forces on the Rheology of Active Gels.

  2018cites this paper
• Thin-film models for an active gel

  2017influential citation
• The Physics of Cancer

  2017cites this paper
• Pattern Formation in Active Nematics

  2017cites this paper
• Force percolation of contractile active gels.

  2017cites this paper
• Spontaneous Formation of a Globally Connected Contractile Network in a Microtubule-Motor System

  2016cites this paper
• Actin flows in cell migration: from locomotion and polarity to trajectories.

  2016cites this paper
• Classical Nucleation Theory Description of Active Colloid Assembly.

  2016cites this paper
• Self-organized stress patterns drive state transitions in actin cortices

  2016cites this paper
• Generalized Swift-Hohenberg models for dense active suspensions

  2016cites this paper
• Activity induces traveling waves, vortices and spatiotemporal chaos in a model actomyosin layer

  2016cites this paper
• An introduction to the statistical physics of active matter: motility-induced phase separation and the “generic instability” of active gels

  2016cites this paper
• Phase Transitions in Model Active Systems

  2016cites this paper
• Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues.

  2016cites this paper
• Negative stiffness and modulated states in active nematics.

  2016cites this paper
• Instabilities, motion and deformation of active fluid droplets

  2016cites this paper
• Active gel physics

  2015cites this paper
• Complex Fluids and Soft Structures in the Human Body

  2015cites this paper
• Purely hydrodynamic ordering of rotating disks at a finite Reynolds number

  2015cites this paper
• Modelling Spontaneous Motion and Deformation of Active Droplets

  2015cites this paper
• An introduction to the physics of active matter

  2015cites this paper
• Kinetic attractor phase diagrams of active nematic suspensions: the dilute regime.

  2015cites this paper
• Percolation mechanism drives actin gels to the critically connected state.

  2015cites this paper
• Stabilization of active matter by flow-vortex lattices and defect ordering

  2015cites this paper
• Antipolar ordering of topological defects in active liquid crystals

  2015cites this paper
• Stress reorganization and response in active solids.

  2014cites this paper
• Physics of microswimmers—single particle motion and collective behavior: a review

  2014cites this paper
• Spontaneous motility of passive emulsion droplets in polar active gels.

  2014cites this paper
• Defect dynamics in active nematics

  2014cites this paper
• Active chiral processes in thin films.

  2013cites this paper
• Collective cell migration: a mechanistic perspective.

  2013cites this paper
• Periodic migration in a physical model of cells on micropatterns.

  2013cites this paper
• Nonequilibrium structure and dynamics in a microscopic model of thin-film active gels.

  2013cites this paper
• Active polar fluid flow in finite droplets

  2013cites this paper
• Active gel model of amoeboid cell motility

  2013cites this paper
• Self-organized vortices of circling self-propelled particles and curved active flagella.

  2013cites this paper
• Defect annihilation and proliferation in active nematics.

  2013cites this paper
• Kinetic theory and simulations of active polar liquid crystalline polymers

  2013cites this paper
• Hydrodynamics of soft active matter

  2013cites this paper
• Colloids in active fluids: anomalous microrheology and negative drag.

  2012cites this paper
• Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

  2012cites this paper
• Bulk rheology and microrheology of active fluids

  2012cites this paper
• A drop of active matter

  2012cites this paper
• Confined active nematic flow in cylindrical capillaries.

  2012cites this paper
• Self-regulation in self-propelled nematic fluids

  2012cites this paper
• Active contractility in actomyosin networks

  2012cites this paper
• Defect hydrodynamics in 2D polar active fluids

  2011cites this paper
• On the spontaneous collective motion of active matter

  2011cites this paper
• Colloids in a bacterial bath: simulations and experiments

  2011cites this paper
• Nonequilibrium steady states in polar active fluids

  2011cites this paper
• Fluctuations and symmetries in two-dimensional active gels

  2011cites this paper
• Polar patterns in active fluids

  2011cites this paper
• Constructing Tools for the Description of Cell Dynamics

  2011cites this paper
• Dynamical self-regulation in self-propelled particle flows.

  2011cites this paper
• Non-conservative forces and effective temperatures in active polymers

  2011cites this paper
• Microscopic basis for pattern formation and anomalous transport in two-dimensional active gels

  2010cites this paper
• Nonlinear rheology of active particle suspensions: insights from an analytical approach.

  2010cites this paper
• Mechanisms of Cell Motion in Confined Geometries

  2010cites this paper
• A Hydrodynamical Kinetic Theory for Self-Propelled Ellipsoidal Suspensions

  2010cites this paper
• Nonlocal fluctuation correlations in active gels.

  2010cites this paper
• Hydrodynamics of non-homogeneous active gels

  2010cites this paper
• Nonlinear dynamics and rheology of active fluids: simulations in two dimensions.

  2010cites this paper
• Excitable patterns in active nematics.

  2010cites this paper
• Pushing off the walls: a mechanism of cell motility in confinement.

  2009cites this paper
• Continuum modeling of forces in growing viscoelastic cytoskeletal networks.

  2009cites this paper
• Formation of Network and Cellular Structures by Viscoelastic Phase Separation

  2009cites this paper
• Active gels as a description of the actin‐myosin cytoskeleton

  2009cites this paper
• Shear-induced dynamic polarization and mesoscopic structure in suspensions of polar nanorods.

  2009cites this paper
• Suspension biomechanics of swimming microbes

  2009cites this paper
• Buckling-induced zebra stripe patterns in nematic F-actin.

  2009cites this paper
• Mathematics of cell motility: have we got its number?

  2009cites this paper
• Large-scale collective behavior of swimming microorganisms at high concentrations.

  2009cites this paper
• Collective swimming and the dynamics of bacterial turbulence.

  2008cites this paper
• Spontaneous flow of active polar gels in undulated channels.

  2008cites this paper
• Enhanced reaction kinetics in biological cells

  2008cites this paper