Role of the GATA family of transcription factors in andrology.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Andrology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 15223831
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Gata4 Regulates Testis Expression of Dmrt1

  2004cited by this paper
• Transcription factor GATA-6, cell proliferation, apoptosis, and apoptosis-related proteins Bcl-2 and Bax in human fetal testis.

  2003cited by this paper
• A tissue-specific knockout reveals that Gata1 is not essential for Sertoli cell function in the mouse.

  2003cited by this paper
• Novel roles for GATA transcription factors in the regulation of steroidogenesis.

  2003cited by this paper
• Transcription Factor GATA-4 Is Activated by Phosphorylation of Serine 261 via the cAMP/Protein Kinase A Signaling Pathway in Gonadal Cells*

  2003cited by this paper
• FOG-2 and GATA-4 Are Coexpressed in the Mouse Ovary and Can Modulate Müllerian-Inhibiting Substance Expression1

  2003cited by this paper
• Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6.

  2003cited by this paper
• GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

  2003cited by this paper
• A Mutated Form of Steroidogenic Factor 1 (SF-1 G35E) That Causes Sex Reversal in Humans Fails to Synergize with Transcription Factor GATA-4*

  2003cited by this paper
• GATA-6 is expressed in the human adrenal and regulates transcription of genes required for adrenal androgen biosynthesis.

  2003cited by this paper
• Friend of GATA (FOG)-1 and FOG-2 differentially repress the GATA-dependent activity of multiple gonadal promoters.

  2002cited by this paper
• Effects of follicle-stimulating hormone (FSH) and human chorionic gonadotropin in individuals with an inactivating mutation of the FSH receptor.

  2002cited by this paper
• Protein kinase A-dependent cooperation between GATA and CCAAT/enhancer-binding protein transcription factors regulates steroidogenic acute regulatory protein promoter activity.

  2002cited by this paper
• Gonadotropins, via cAMP, negatively regulate GATA-1 gene expression in testicular cells.

  2002cited by this paper
• Developmental expression and spermatogenic stage specificity of transcription factors GATA-1 and GATA-4 and their cofactors FOG-1 and FOG-2 in the mouse testis.

  2002cited by this paper
• Sexually dimorphic expression of Gata-2 during mouse gonad development.

  2002cited by this paper
• Gonadal differentiation, sex determination and normal Sry expression in mice require direct interaction between transcription partners GATA4 and FOG2.

  2002cited by this paper
• New signaling pathways for hormones and cyclic adenosine 3',5'-monophosphate action in endocrine cells.

  2001cited by this paper
• Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors.

  2001cited by this paper
• Müllerian inhibiting substance: an instructive developmental hormone with diagnostic and possible therapeutic applications.

  2001cited by this paper
• GATA factors differentially activate multiple gonadal promoters through conserved GATA regulatory elements.

  2001cited by this paper
• Modulation of endogenous GATA-4 activity reveals its dual contribution to Müllerian inhibiting substance gene transcription in Sertoli cells.

  2001cited by this paper
• The Transcription Factor GATA4 Is Activated by Extracellular Signal-Regulated Kinase 1- and 2-Mediated Phosphorylation of Serine 105 in Cardiomyocytes

  2001cited by this paper
• E2F and GATA-1 are required for the Sertoli cell-specific promoter activity of the follicle-stimulating hormone receptor gene.

  2001cited by this paper
• Temporal and Spatial Localization Patterns of Gata4 During Porcine Gonadogenesis1

  2001cited by this paper
• Transcriptional regulation by the phosphorylation-dependent factor CREB

  2001cited by this paper
• Nuclear Receptor Dax-1 Represses the Transcriptional Cooperation Between GATA-4 and SF-1 in Sertoli Cells1

  2001cited by this paper
• GATA-1 and GATA-4 transactivate inhibin/activin beta-B-subunit gene transcription in testicular cells.

  2000cited by this paper
• GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1-dependent transcription.

  2000cited by this paper
• Expression and subcellular localization of SF‐1, SOX9, WT1, and AMH proteins during early human testicular development

  2000cited by this paper
• Transcription factors GATA-4 and GATA-6 and a GATA family cofactor, FOG-2, are expressed in human ovary and sex cord-derived ovarian tumors.

  2000cited by this paper
• A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2

  2000cited by this paper
• Abnormalities of the Genitourinary Tract in Female Mice Lacking GATA5

  2000cited by this paper
• Endogenous expression of Müllerian inhibiting substance in early postnatal rat sertoli cells requires multiple steroidogenic factor-1 and GATA-4-binding sites.

  2000cited by this paper
• GATA3 haplo-insufficiency causes human HDR syndrome

  2000cited by this paper
• A role for GATA transcription factors in the androgen regulation of the prostate-specific antigen gene enhancer.

  2000cited by this paper
• Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

  2000cited by this paper
• The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6

  2000cited by this paper
• GATA factor transgenes under GATA-1 locus control rescue germline GATA-1 mutant deficiencies.

  2000cited by this paper
• A Functionally Conserved N-terminal Domain of the Friend of GATA-2 (FOG-2) Protein Represses GATA4-Dependent Transcription*

  2000cited by this paper
• FOG-2, a cofactor for GATA transcription factors, is essential for heart morphogenesis and development of coronary vessels from epicardium.

  2000cited by this paper
• Steroidogenic factor-1 influences protein-deoxyribonucleic acid interactions within the cyclic adenosine 3,5-monophosphate-responsive regions of the murine steroidogenic acute regulatory protein gene.

  2000cited by this paper
• GATA‐dependent recruitment of MEF2 proteins to target promoters

  2000cited by this paper
• Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development.

  1999cited by this paper
• The transcription factor GATA6 is essential for early extraembryonic development.

  1999cited by this paper
• Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types.

  1999cited by this paper
• Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes.

  1999cited by this paper
• CCAAT Enhancer-binding Protein β and GATA-4 Binding Regions within the Promoter of the Steroidogenic Acute Regulatory Protein (StAR) Gene Are Required for Transcription in Rat Ovarian Cells*

  1999cited by this paper
• hFOG-2, a Novel Zinc Finger Protein, Binds the Co-repressor mCtBP2 and Modulates GATA-mediated Activation*

  1999cited by this paper
• Transcription factor GATA-4 enhances Müllerian inhibiting substance gene transcription through a direct interaction with the nuclear receptor SF-1.

  1999cited by this paper
• FOG-2: A novel GATA-family cofactor related to multitype zinc-finger proteins Friend of GATA-1 and U-shaped.

  1999cited by this paper
• Transcriptional cofactors of the FOG family interact with GATA proteins by means of multiple zinc fingers

  1999cited by this paper
• FOG-2, a Heart- and Brain-Enriched Cofactor for GATA Transcription Factors

  1999cited by this paper
• Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells.

  1999cited by this paper
• GATA transcription factors and cardiac development.

  1999cited by this paper
• The Cardiac Tissue-Restricted Homeobox Protein Csx/Nkx2.5 Physically Associates with the Zinc Finger Protein GATA4 and Cooperatively Activates Atrial Natriuretic Factor Gene Expression

  1998cited by this paper
• TAL1 and LIM-Only Proteins Synergistically Induce Retinaldehyde Dehydrogenase 2 Expression in T-Cell Acute Lymphoblastic Leukemia by Acting as Cofactors for GATA3

  1998cited by this paper
• GATA transcription factors as potentiators of gut endoderm differentiation.

  1998cited by this paper
• A calcineurin-dependent transcriptional pathway for cardiac hypertrophy.

  1998cited by this paper
• Testicular GATA-1 factor up-regulates the promoter activity of rat inhibin alpha-subunit gene in MA-10 Leydig tumor cells.

  1998cited by this paper
• Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Müllerian inhibiting substance promoter.

  1998cited by this paper
• Cloning and characterization of mCtBP2, a co‐repressor that associates with basic Krüppel‐like factor and other mammalian transcriptional regulators

  1998cited by this paper
• GATA6 regulates HNF4 and is required for differentiation of visceral endoderm in the mouse embryo.

  1998cited by this paper
• Cyclic AMP signaling and gene regulation.

  1998cited by this paper
• Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG.

  1998cited by this paper
• Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA‐2 in urogenital development

  1998cited by this paper
• Pit-1 and GATA-2 Interact and Functionally Cooperate to Activate the Thyrotropin β-Subunit Promoter*

  1997cited by this paper
• Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter.

  1997cited by this paper
• Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements.

  1997cited by this paper
• Transcriptional regulation by cyclic AMP.

  1997cited by this paper
• GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

  1997cited by this paper
• GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development.

  1997cited by this paper
• A lineage‐selective knockout establishes the critical role of transcription factor GATA‐1 in megakaryocyte growth and platelet development

  1997cited by this paper
• The proximal promoter region of the gene encoding human 17beta-hydroxysteroid dehydrogenase type 1 contains GATA, AP-2, and Sp1 response elements: analysis of promoter function in choriocarcinoma cells.

  1997cited by this paper
• The nuclear receptor SF-1 mediates sexually dimorphic expression of Mullerian Inhibiting Substance, in vivo.

  1997cited by this paper
• FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation.

  1997cited by this paper
• The cardiac transcription factors Nkx2‐5 and GATA‐4 are mutual cofactors

  1997cited by this paper
• Expression and hormonal regulation of transcription factors GATA-4 and GATA-6 in the mouse ovary.

  1997cited by this paper
• Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

  1997cited by this paper
• GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm.

  1996cited by this paper
• Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

  1996cited by this paper
• Transcription factor GATA-3 is required for development of the T-cell lineage

  1996cited by this paper
• Functional interaction of GATA1 with erythroid Krüppel-like factor and Sp1 at defined erythroid promoters.

  1996cited by this paper
• Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis.

  1995cited by this paper
• Development of hematopoietic cells lacking transcription factor GATA-1.

  1995cited by this paper
• GATA transcription factors: key regulators of hematopoiesis.

  1995cited by this paper
• Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1.

  1995cited by this paper
• Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

  1995cited by this paper
• Rescue of GATA-1-deficient embryonic stem cells by heterologous GATA-binding proteins

  1995cited by this paper
• Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Krüppel family proteins Sp1 and EKLF

  1995cited by this paper
• Regulation of Drosophila yolk protein genes by an ovary-specific GATA factor

  1995cited by this paper
• Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene

  1995cited by this paper
• Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells.

  1994cited by this paper
• A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription

  1994cited by this paper
• GATA-type zinc finger motif-containing sequences and chorion gene transcription factors of the silkworm Bombyx mori.

  1994cited by this paper
• An early haematopoietic defect in mice lacking the transcription factor GATA-2

  1994cited by this paper
• Sex- and tissue-specific Bkm(GATA)-binding protein in the germ cells of heterogametic sex.

  1994cited by this paper
• Temporal and spatial changes in GATA transcription factor expression are coincident with development of the chicken optic tectum.

  1994cited by this paper
• GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

  1994cited by this paper
• Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: a link to the sex determination cascade.

  1994cited by this paper

• Genome-Wide Identification and Evolutionary Analysis of the GATA Transcription Factor Family in Nitrogen-Fixing Legumes

  2025cites this paper
• Whole-Exome Sequencing Identifies Novel GATA5/6 Variants in Right-Sided Congenital Heart Defects

  2025cites this paper
• Potential Prognostic Value of GATA4 Depends on the p53 Expression in Primary Glioblastoma Patients

  2023cites this paper
• Chicken ovalbumin upstream promoter transcription factor type II interacts and functionally cooperates with GATA4 to regulate anti‐Müllerian hormone receptor type 2 transcription in mouse MA‐10 Leydig cells

  2022cites this paper
• Transcription Factors in the Regulation of Leydig Cell Gene Expression and Function

  2022cites this paper
• Insights Into the Roles of GATA Factors in Mammalian Testis Development and the Control of Fetal Testis Gene Expression

  2022cites this paper
• A Short Promoter Region Containing Conserved Regulatory Motifs Is Required for Steroidogenic Acute Regulatory Protein (Star) Gene Expression in the Mouse Testis

  2022cites this paper
• Differential Response of Transcription Factors to Activated Kinases in Steroidogenic and Non-Steroidogenic Cells

  2022cites this paper
• GATA-1 mutation alters the spermatogonial phase and steroidogenesis in adult mouse testis.

  2021cites this paper
• Transcriptional Inhibition of Sp-IAG by Crustacean Female Sex Hormone in the Mud Crab, Scylla paramamosain

  2020cites this paper
• Phosphorylation of GATA4 serine 105 but not serine 261 is required for testosterone production in the male mouse

  2019cites this paper
• Motif elucidation in ChIP-seq datasets with a knockout control

  2019cites this paper
• Direct conversion of human fibroblasts into functional Leydig-like cells by SF-1, GATA4 and NGFI-B.

  2018cites this paper
• GATA4 knockdown in MA-10 Leydig cells identifies multiple target genes in the steroidogenic pathway.

  2015influential citation
• Notch signaling represses GATA4-induced expression of genes involved in steroid biosynthesis.

  2015cites this paper
• Myocyte enhancer factor 2 (MEF2) : un facteur impliqué dans le maintien des fonctions stéroïdogéniques des cellules de Leydig

  2015cites this paper
• Identification of a novel ovine LH-beta promoter region, which dramatically enhances its promoter activity

  2015cites this paper
• Differential role of the estrogen receptors ESR1 and ESR2 on the regulation of proteins involved with proliferation and differentiation of Sertoli cells from 15-day-old rats.

  2014cites this paper
• GATA1: a novel target for gene therapy in major depressive disorder

  2014cites this paper
• The Transcription Factors GATA-1 and GATA-4 Have Opposite Effects on DNA Expression Driven by an Amh Promoter

  2014cites this paper
• Tzfp Represses the Androgen Receptor in Mouse Testis

  2013cites this paper
• Interaction between the Wilms tumour factor-1 element in the promoter of Amh and a downstream enhancer is required for a strong expression of the gene in pre-pubertal sertoli cells

  2013cites this paper
• Autorégulation du gène GATA4 via son promoteur distal 1B dans les cellules gonadiques

  2013cites this paper
• Mutated elements of a complex promoter (Amh) can help to demonstrate the role of certain elements in controlling differential gene expression

  2012cites this paper
• The expression mechanism of glutathione S-transferase theta 1 (GSTT1) as an aging marker

  2012cites this paper
• GATA-4 and FOG-2 Expression in Pediatric Ovarian Sex Cord-Stromal Tumors Replicates Embryonal Gonadal Phenotype: Results from the TREP Project

  2012cites this paper
• Genes promoting and disturbing testis development.

  2012cites this paper
• GATA4 Autoregulates Its Own Expression in Mouse Gonadal Cells via Its Distal 1b Promoter1

  2011cites this paper
• Expression and Relevance of TRPS-1: A New GATA Transcription Factor in Breast Cancer

  2011cites this paper
• Control genético del desarrollo gonadal de Talpa occidentalis

  2011cites this paper
• Leydig cell aging and the mechanisms of reduced testosterone synthesis.

  2009cites this paper
• Complex assembly on the human CYP17 promoter.

  2009cites this paper
• Regulation of sperm gene expression by the GATA factor ELT-1.

  2009cites this paper
• Conserved Usage of Alternative 5′ Untranslated Exons of the GATA4 Gene

  2009cites this paper
• A role for GATA-6 in vertebrate chondrogenesis.

  2008cites this paper
• The effect of human GATA4 gene mutations on the activity of target gonadal promoters.

  2008cites this paper
• GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.

  2008cites this paper
• Novel pre‐ and post‐gastrulation expression of Gata4 within cells of the inner cell mass and migratory neural crest cells

  2008cites this paper
• GATA Factors and Androgen Receptor Collaborate To Transcriptionally Activate the Rhox5 Homeobox Gene in Sertoli Cells

  2008cites this paper
• Transcription regulation in spermatogenesis.

  2008cites this paper
• Expression of GATA-6 transcription factor in pleural malignant mesothelioma and metastatic pulmonary adenocarcinoma

  2008cites this paper
• Role of the GATA family of transcription factors in endocrine development, function, and disease.

  2008cites this paper
• Expression of CLMP, a novel tight junction protein, is mediated via the interaction of GATA with the kruppel family proteins, KLF4 and Sp1, in mouse TM4 sertoli cells

  2008cites this paper
• Molecular mechanisms in spermatogenesis

  2008cites this paper
• Transcription Factors as Regulators of Gene Expression During Leydig Cell Differentiation and Function

  2007cites this paper
• Steroidogenic Enzymes in Leydig Cells

  2007cites this paper
• Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice

  2007cites this paper
• Dual transcriptional control of claudin‐11 via an overlapping GATA/NF‐Y motif: Positive regulation through the interaction of GATA, NF‐YA, and CREB and negative regulation through the interaction of Smad, HDAC1, and mSin3A

  2007cites this paper
• The Proximal Gata4 Promoter Directs Reporter Gene Expression to Sertoli Cells During Mouse Gonadal Development1

  2007cites this paper
• Disruption of Friend of GATA 2 gene (FOG‐2) by a de novo t(8;10) chromosomal translocation is associated with heart defects and gonadal dysgenesis

  2007cites this paper
• Genetic variations of VDR/NR1I1 encoding vitamin D receptor in a Japanese population.

  2007cites this paper
• LRH-1/NR5A2 cooperates with GATA factors to regulate inhibin alpha-subunit promoter activity.

  2006cites this paper
• Follicle-stimulating hormone-induced aromatase in immature rat Sertoli cells requires an active phosphatidylinositol 3-kinase pathway and is inhibited via the mitogen-activated protein kinase signaling pathway.

  2006cites this paper
• FSH-Induced Aromatase in Immature Rat Sertoli Cells Requires an Active Phosphatidylinositol 3-kinase Pathway and is Inhibited via the Mitogen- activated Protein Kinase Signaling Pathway

  2005cites this paper
• Gene regulation in spermatogenesis.

  2005cites this paper
• Protein kinase A-dependent synergism between GATA factors and the nuclear receptor, liver receptor homolog-1, regulates human aromatase (CYP19) PII promoter activity in breast cancer cells.

  2005cites this paper
• The Effect of Human Gata4 Gene Mutations on the Activity of Target Gonadal Promoters

  year unknowncites this paper