Drusen-associated degeneration in the retina.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Investigative Ophthalmology and Visual Science

• Publication date

  2003-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1167/IOVS.03-0436PMID 14507896
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Macular drusen and the sensitivity of the central visual field

  2005cited by this paper
• CLINICOPATHOLOGIC CORRELATION OF DRUSEN AND RETINAL PIGMENT EPITHELIAL ABNORMALITIES IN AGE-RELATED MACULAR DEGENERATION

  2005influential reference
• Evidence that ganglion cells react to retinal detachment.

  2003cited by this paper
• The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration.

  2002cited by this paper
• The role of apoptosis in age-related macular degeneration.

  2002cited by this paper
• The Alzheimer's Aβ-peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration

  2002cited by this paper
• Phenotypic variation of retinal pigment epithelium in age-related macular degeneration.

  2002cited by this paper
• A role for local inflammation in the formation of drusen in the aging eye.

  2002cited by this paper
• MORPHOMETRIC ANALYSIS OF THE MACULA IN EYES WITH DISCIFORM AGE-RELATED MACULAR DEGENERATION

  2002cited by this paper
• Developmental death of photoreceptors in the C57BL/6J mouse: association with retinal function and self-protection.

  2002cited by this paper
• Regulation by oxygen of photoreceptor death in the developing and adult C57BL/6J mouse.

  2002cited by this paper
• Amyloid-beta peptide is toxic to neurons in vivo via indirect mechanisms.

  2002cited by this paper
• Drusen proteome analysis: An approach to the etiology of age-related macular degeneration

  2002cited by this paper
• Preservation of ganglion cell layer neurons in age-related macular degeneration.

  2001cited by this paper
• The ability of hyperoxia to limit the effects of experimental detachment in cone-dominated retina.

  2001cited by this paper
• Local cellular sources of apolipoprotein E in the human retina and retinal pigmented epithelium: implications for the process of drusen formation.

  2001cited by this paper
• An integrated hypothesis that considers drusen as biomarkers of immune-mediated processes at the RPE-Bruch's membrane interface in aging and age-related macular degeneration.

  2001cited by this paper
• Risk factors for age-related macular degeneration.

  2001cited by this paper
• Accumulation of cholesterol with age in human Bruch's membrane.

  2001cited by this paper
• The role of the retinal pigment epithelium: Topographical variation and ageing changes

  2001cited by this paper
• Immunological and aetiological aspects of macular degeneration.

  2001cited by this paper
• Complement activation and inflammatory processes in Drusen formation and age related macular degeneration.

  2001cited by this paper
• Changes of astrocytes in retinal ageing and age-related macular degeneration.

  2001cited by this paper
• Delays in rod-mediated dark adaptation in early age-related maculopathy.

  2001cited by this paper
• A potential role for immune complex pathogenesis in drusen formation.

  2000cited by this paper
• Metabolic dependence of photoreceptors on the choroid in the normal and detached retina.

  2000cited by this paper
• Limiting photoreceptor death and deconstruction during experimental retinal detachment: the value of oxygen supplementation.

  1999cited by this paper
• Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study

  1999cited by this paper
• Histopathology of age-related macular degeneration.

  1999cited by this paper
• The Alabama Age-Related Macular Degeneration Grading System for donor eyes.

  1998cited by this paper
• In the eye

  1998cited by this paper
• Alzheimer's peptide kills cells of retina in vivo

  1998cited by this paper
• Photoreceptor loss in age-related macular degeneration.

  1996cited by this paper
• An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group.

  1995cited by this paper
• An international classification and grading system for age-related maculopathy and age-related macular degeneration

  1995cited by this paper
• INTERMEDIATE FILAMENT EXPRESSION IN HUMAN RETINAL MACROGLIA: Histopathologic Changes Associated With Age‐Related Macular Degeneration

  1994cited by this paper
• Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa.

  1994cited by this paper
• Drusen as risk factors in age-related macular disease.

  1990influential reference
• Relationship of drusen and abnormalities of the retinal pigment epithelium to the prognosis of neovascular macular degeneration. The Macular Photocoagulation Study Group.

  1990cited by this paper
• Color matching and the Stiles-Crawford effect in observers with early age-related macular changes.

  1988cited by this paper
• Retinal sensitivity over drusen and nondrusen areas. A study using fundus perimetry.

  1988cited by this paper
• Formation of drusen in the human eye.

  1986cited by this paper
• Drusen patterns predisposing to geographic atrophy of the retinal pigment epithelium.

  1982cited by this paper
• Clinico-morphologic correlations of drusen of Bruch's membrane.

  1980cited by this paper
• Role of the retinal pigment epithelium in macular disease.

  1972cited by this paper
• The ultrastructure of drusen.

  1971cited by this paper

• The gut-retina axis in age-related macular degeneration: immune crosstalk and metabolite production

  2026cites this paper
• Brain-derived neurotrophic factor in age-related macular degeneration.

  2026cites this paper
• Turquoise killifish naturally develop hallmarks of age-related macular degeneration with advancing age

  2025cites this paper
• Generation of iPSCs (RFSCi007-A, RFSCi008-A) from a patient with early-onset bilateral drusen and a healthy sibling for retinal disease modeling.

  2025cites this paper
• An improved deep learning approach for automated detection of multiclass eye diseases

  2025cites this paper
• Exosome’s Implications in Age-Related Macular Degeneration

  2025cites this paper
• Ref-1 is overexpressed in neovascular eye disease and targetable with a novel inhibitor

  2025cites this paper
• Peptide Lv Deficiency Adversely Impacts the Structural and Functional Integrity of the Neural Retina

  2025cites this paper
• Associations Between Structural Phenotype and Polygenic Risk Scores in Intermediate Age-Related Macular Degeneration – A MACUSTAR Report

  2025cites this paper
• A comprehensive review of structure-function correlations in age-related macular degeneration: Contributions of microperimetry.

  2025cites this paper
• Long-term effects of drusenoid pigment epithelial detachment on the retina and the choroid.

  2025cites this paper
• Dynamics of Structural and Functional Changes of Patients with Dry Form Age-related Macular Degeneration after Double Filtration Plasmapheresis

  2024cites this paper
• The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases

  2024cites this paper
• Dynamics of rheological and biochemical blood parameters of patients with an intermediate stage of the dry form of age-related macular degeneration before and after serum cascade filtration

  2024cites this paper
• Photoreceptor assessment in age-related macular degeneration

  2024cites this paper
• PEDF-derived peptide protects against Amyloid-β toxicity in vitro and prevents retinal dysfunction in rats.

  2024cites this paper
• Characterization of Ocular Morphology in Col4a3−/− Mice as a Murine Model for Alport Syndrome

  2024cites this paper
• Müller Glial Cells in the Macula: Their Activation and Cell-Cell Interactions in Age-Related Macular Degeneration

  2024cites this paper
• Probing Deposit-Driven Age-Related Macular Degeneration Via Thicknesses of Outer Retinal Bands and Choroid: ALSTAR2 Baseline

  2024cites this paper
• The role of immune modulators in age-related macular degeneration.

  2024cites this paper
• Spatial Cluster Patterns of Retinal Sensitivity Loss in Intermediate Age-Related Macular Degeneration Features

  2023cites this paper
• Evaluation of the microperimetry in eyes with cuticular drusen

  2022cites this paper
• High-Density Optical Coherence Tomography Analysis Provides Insights Into Early/Intermediate Age-Related Macular Degeneration Retinal Layer Changes

  2022cites this paper
• Retinal Aging Transcriptome and Cellular Landscape in Association With the Progression of Age-Related Macular Degeneration

  2022cites this paper
• Harnessing the Neuroprotective Behaviors of Müller Glia for Retinal Repair

  2022cites this paper
• Reticular Pseudodrusen Are Associated With More Advanced Para-Central Photoreceptor Degeneration in Intermediate Age-Related Macular Degeneration

  2022cites this paper
• Does outer retinal layer thickness correlate with the central visual field indices in early dry age-related macular degeneration?

  2022cites this paper
• Should clinical automated perimetry be considered for routine functional assessment of early/intermediate age‐related macular degeneration (AMD)? A systematic review of current literature

  2021cites this paper
• The Relationship Between Perifoveal L-Cone Isolating Visual Acuity and Cone Photoreceptor Spacing—Understanding the Transition Between Healthy Aging and Early AMD

  2021cites this paper
• Pathogenic mechanisms contributing to the vulnerability of aging human photoreceptor cells

  2021cites this paper
• Location-Specific Thickness Patterns in Intermediate Age-Related Macular Degeneration Reveals Anatomical Differences in Multiple Retinal Layers

  2021cites this paper
• The interplay of oxidative stress and ARMS2-HTRA1 genetic risk in neovascular AMD

  2021cites this paper
• Clinically-identified C-terminal mutations in fibulin-3 are prone to misfolding and destabilization

  2021cites this paper
• Retinal Fundus Multi-Disease Image Dataset (RFMiD): A Dataset for Multi-Disease Detection Research

  2021cites this paper
• MicroRNAs as diagnostic and prognostic biomarkers of age-related macular degeneration: advances and limitations

  2020cites this paper
• Identification of functional markers for detecting vision loss in early and intermediate age-related macular degeneration

  2020influential citation
• Neural Engineering

  2020cites this paper
• Adaptive optics: principles and applications in ophthalmology

  2020cites this paper
• The retinal toxicity profile towards assemblies of Amyloid-β indicate the predominant pathophysiological activity of oligomeric species

  2020cites this paper
• Beneficial effects of saffron (Crocus sativus L.) in ocular pathologies, particularly neurodegenerative retinal diseases

  2020cites this paper
• Mitochondrial dysfunction in age-related macular degeneration: melatonin as a potential treatment

  2020cites this paper
• Retinal Bioengineering

  2020cites this paper
• Association of Visual Function Measures with Drusen Volume in Early Stages of Age-Related Macular Degeneration

  2020cites this paper
• SUBRETINAL DRUSENOID DEPOSIT IN AGE-RELATED MACULAR DEGENERATION: Histologic Insights Into Initiation, Progression to Atrophy, and Imaging.

  2020cites this paper
• Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration.

  2019cites this paper
• In vitro drusen model – three-dimensional spheroid culture of retinal pigment epithelial cells

  2019cites this paper
• Scaffolds for retinal repairs

  2019cites this paper
• Biofabrication of choroid-retina tissue construct for modelling of age-related macular degeneration disease

  2019cites this paper
• Retina Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration

  2019cites this paper
• Modulating GLUT1 expression in retinal pigment epithelium decreases glucose levels in the retina: impact on photoreceptors and Müller glial cells.

  2019cites this paper
• Polypoidal Choroidal Vasculopathy: Outer Retinal and Choroidal Changes and Neovascularization Development in the Fellow Eye.

  2019cites this paper
• Cone photoreceptor macular function and recovery after photostress in early non-exudative age-related macular degeneration

  2018cites this paper
• Retinal Thickness Changes throughout the Natural History of Drusen in Age-related Macular Degeneration.

  2018cites this paper
• On the origin of proteins in human drusen: The meet, greet and stick hypothesis.

  2018cites this paper
• Endogenous Cell Sources for Eye Retina Regeneration in Vertebrate Animals and Humans

  2018cites this paper
• Novel devices for studying acute and chronic mechanical stress in retinal pigment epithelial cells.

  2018cites this paper
• Tissue engineering of retina and Bruch’s membrane: a review of cells, materials and processes

  2018cites this paper
• Subretinal Glial Membranes in Eyes With Geographic Atrophy

  2017cites this paper
• Histological study on the detrimental influences of white LED light on the retina of adult albino rat and the potential effect of simultaneous nicotine administration with highlighting their possible mechanisms

  2017cites this paper
• IMPROVING THE AGE-RELATED MACULAR DEGENERATION CONSTRUCT: A New Classification System.

  2017cites this paper
• Retinal oxygen: from animals to humans.

  2017cites this paper
• Retinal cell death dependent reactive proliferative gliosis in the mouse retina

  2017cites this paper
• The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy

  2017cites this paper
• Photoreceptor-Based Biomarkers in AOSLO Retinal Imaging

  2017cites this paper
• Quantification of retinal changes after resolution of submacular hemorrhage secondary to polypoidal choroidal vasculopathy

  2017cites this paper
• Microperimetry in age: related macular degeneration

  2017cites this paper
• Early deterioration in ellipsoid zone in eyes with non-neovascular age-related macular degeneration

  2017cites this paper
• Photoreceptor-Based Biomarkers in Retinal Imaging.

  2017cites this paper
• Multimodal imaging of small hard retinal drusen in young healthy adults

  2017cites this paper
• The Role of Mitochondria-Associated Reactive Oxygen Species in the Amyloid β Induced Production of Angiogenic Factors b y ARPE-19 Cells.

  2017cites this paper
• OPTICAL COHERENCE TOMOGRAPHY AND HISTOLOGY OF AGE-RELATED MACULAR DEGENERATION SUPPORT MITOCHONDRIA AS REFLECTIVITY SOURCES

  2017cites this paper
• Retinal Remodeling and Metabolic Alterations in Human AMD

  2016cites this paper
• Analysis of Macular Drusen and Blood Test Results in 945 Macaca fascicularis

  2016cites this paper
• Multi-surface segmentation of OCT images with AMD using sparse high order potentials.

  2016cites this paper
• Amyloidosis in Retinal Neurodegenerative Diseases

  2016cites this paper
• Photoreceptor dysfunction in early and intermediate age-related macular degeneration assessed with mfERG and spectral domain OCT

  2016cites this paper
• Drusen maculopathy: a risk factor for visual deterioration

  2016cites this paper
• Glycemic Index and Diabetes Mellitus: Evidence on Prevention and Management and Implications on Insulin Resistance

  2016cites this paper
• ASSESSING PHOTORECEPTOR STRUCTURE ASSOCIATED WITH ELLIPSOID ZONE DISRUPTIONS VISUALIZED WITH OPTICAL COHERENCE TOMOGRAPHY

  2016cites this paper
• Radiating hemorrhage in exudative age-related macular degeneration

  2016cites this paper
• Evaluating the performance of the quick CSF method in detecting contrast sensitivity function changes

  2016cites this paper
• Impairments in Dark Adaptation Are Associated with Age-Related Macular Degeneration Severity and Reticular Pseudodrusen.

  2015cites this paper
• Adaptive optics ophthalmoscopy.

  2015cites this paper
• Evaluating the Performance of the Quick CSF Method in Detecting CSF Changes: An Assay Calibration Study

  2015cites this paper
• The value of multifocal electroretinography to predict progressive visual acuity loss in early AMD

  2015cites this paper
• Matrix γ-carboxyglutamate protein and Fetuin-A, in wet type age-related macular degeneration.

  2015cites this paper
• Drusen and Photoreceptor Abnormalities in African-Americans with Intermediate Non-neovascular Age-related Macular Degeneration

  2015cites this paper
• CYTOKINES IN LACRIMAL FLUID AND BLOOD SERUM: EARLY BIOMARKERS OF AGE-RELATED MACULAR DEGENERATION

  2015cites this paper
• MULTIMODAL VISUAL FUNCTION TESTING IN EYES WITH NONEXUDATIVE AGE-RELATED MACULAR DEGENERATION

  2015cites this paper
• Melanopsin-Mediated Post-Illumination Pupil Response in Early Age-Related Macular Degeneration.

  2015cites this paper
• Spatial and temporal aspects of visual performance in relation to light level and normal aging

  2015cites this paper
• In vivo quantification of retinal changes associated with drusen in age-related macular degeneration.

  2015cites this paper
• Inner Segment Remodeling and Mitochondrial Translocation in Cone Photoreceptors in Age-Related Macular Degeneration With Outer Retinal Tubulation.

  2015cites this paper
• Photoreceptor Layer Changes Overlying Drusen in Eyes with Age-Related Macular Degeneration Associated with Vitreomacular Traction

  2014cites this paper
• The influence of elastin degradation products, glucose and atorvastatin on metalloproteinase-1, -2, -9 and tissue inhibitor of metalloproteinases-1, -2, -3 expression in human retinal pigment epithelial cells.

  2014cites this paper
• Quantitative Analysis of Cone Photoreceptor Distribution and Its Relationship with Axial Length, Age, and Early Age-Related Macular Degeneration

  2014cites this paper
• IN VIVO IMAGING OF HUMAN CONE PHOTORECEPTOR INNER SEGMENTS 1

  2014cites this paper
• Long-term retinal cone survival and delayed alteration of the cone mosaic in a transgenic mouse model of stargardt-like dystrophy (STGD3).

  2014cites this paper
• In vivo imaging of human cone photoreceptor inner segments.

  2014cites this paper
• Relationship between retinal microstructures on optical coherence tomography and microperimetry in age-related macular degeneration.

  2014cites this paper