Time-dependent effects of intermittent hydrostatic pressure on articular chondrocyte type II collagen and aggrecan mRNA expression.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of rehabilitation research and development

• Publication date

  2000-03-01

• Fields of study

  Medicine, Engineering

• Identifiers
  PMID 10850821
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential effects of hydrostatic pressure on cation transport pathways of isolated articular chondrocytes

  1999cited by this paper
• Modulation of Na+ x H+ exchange by hydrostatic pressure in isolated bovine articular chondrocytes.

  1999cited by this paper
• Load-controlled compression of articular cartilage induces a transient stimulation of aggrecan gene expression.

  1998cited by this paper
• The influence of elaborated pericellular matrix on the deformation of isolated articular chondrocytes cultured in agarose.

  1998cited by this paper
• Articular cartilage repair and transplantation.

  1998cited by this paper
• Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation.

  1998cited by this paper
• Nitric oxide and G proteins mediate the response of bovine articular chondrocytes to fluid‐induced shear

  1997cited by this paper
• Hyperpolarisation of cultured human chondrocytes following cyclical pressure‐induced strain: Evidence of a role for α5β1 integrin as a chondrocyte mechanoreceptor

  1997cited by this paper
• Hyperpolarisation of cultured human chondrocytes following cyclical pressure-induced strain: evidence of a role for alpha 5 beta 1 integrin as a chondrocyte mechanoreceptor.

  1997cited by this paper
• Effects of Hydrostatic Pressure on Matrix Synthesis and Matrix Metalloproteinase Production in the Human Lumbar Intervertebral Disc

  1997cited by this paper
• Hydrostatic pressur influences mRNA exprssion of trnsforming growth factor‐β1 and heat shock protein 70 in chondrocyte‐like cell line

  1997cited by this paper
• The proteoglycan metabolism of mature bovine articular cartilage explants superimposed to continuously applied cyclic mechanical loading.

  1997cited by this paper
• Chondrocyte biosynthesis correlates with local tissue strain in statically compressed adult articular cartilage

  1997cited by this paper
• Compressive strains at physiological frequencies influence the metabolism of chondrocytes seeded in agarose

  1997cited by this paper
• Osteoarthritis: Differential expression of matrix metalloproteinase‐9 mRNA in nonfibrillated and fibrillated cartilage

  1997cited by this paper
• The cellular physiology of articular cartilage

  1996cited by this paper
• Expression of interleukin‐6 in osteoarthritic chondrocytes and effects of fluid‐induced shear on this expression in normal human chondrocytes in vitro

  1996cited by this paper
• In vitro stimulation of articular chondrocyte mRNA and extracellular matrix synthesis by hydrostatic pressure

  1996cited by this paper
• Influence of short‐term hydrostatic pressure on organization of stress fibers in cultured chondrocytes

  1995cited by this paper
• Dynamic behavior of a biphasic cartilage model under cyclic compressive loading.

  1995cited by this paper
• Compression-induced changes in the shape and volume of the chondrocyte nucleus.

  1995cited by this paper
• Effects of fluid‐induced shear on articular chondrocyte morphology and metabolism in vitro

  1995cited by this paper
• The role of cartilage streaming potential, fluid flow and pressure in the stimulation of chondrocyte biosynthesis during dynamic compression.

  1995cited by this paper
• Quantitative polymerase chain reaction assay for aggrecan and link protein gene expression in cartilage.

  1995cited by this paper
• Modulation of extracellular matrix gene expression in bovine high-density chondrocyte cultures by ascorbic acid and enzymatic resuspension.

  1994cited by this paper
• Expression of reduced amounts of structurally altered aggrecan in articular cartilage chondrocytes exposed to high hydrostatic pressure.

  1994cited by this paper
• A triphasic theory for the swelling and deformation behaviors of articular cartilage.

  1991cited by this paper
• The effects of hydrostatic pressure on matrix synthesis in articular cartilage

  1991cited by this paper
• Mechanical Stresses in Joint Morphogenesis and Maintenance

  1990cited by this paper
• Effects of proteoglycan extraction on the tensile behavior of articular cartilage

  1990cited by this paper
• A finite deformation theory for cartilage and other soft hydrated connective tissues--I. Equilibrium results.

  1990cited by this paper
• Theoretical stress analysis of organ culture osteogenesis.

  1990cited by this paper
• Stimulation of adult chondrocyte metabolism by a thyroid‐derived factor

  1990cited by this paper
• Biphasic indentation of articular cartilage--II. A numerical algorithm and an experimental study.

  1989cited by this paper
• Proteoglycans Synthesized by Chondrocytes of Human Nonarthritic and Osteoarthritic Cartilage

  1989cited by this paper
• Biosynthetic response of cartilage explants to dynamic compression

  1989cited by this paper
• Qualitative changes in human osteoarthritic hip cartilage proteoglycan synthesis during long-term explant culture.

  1988cited by this paper
• Mechanical and physicochemical determinants of the chondrocyte biosynthetic response

  1988cited by this paper
• The role of mechanical loading histories in the development of diarthrodial joints

  1988cited by this paper
• Relation of coxarthrosis to stresses and morphogenesis. A finite element analysis.

  1987cited by this paper
• The growth of cartilage cells in vitro and the effect of intermittent compressive force. A histological evaluation.

  1987cited by this paper
• Influences of Mechanical Stress on Prenatal and Postnatal Skeletal Development

  1987cited by this paper
• Influence of intermittent compressive force on proteoglycan content in calcifying growth plate cartilage in vitro.

  1987cited by this paper
• Effects of Immobilization on Joints

  1987cited by this paper
• The chondrogenic potential of free autogenous periosteal grafts for biological resurfacing of major full-thickness defects in joint surfaces under the influence of continuous passive motion. An experimental investigation in the rabbit.

  1986cited by this paper
• Articular Cartilage Breakdown in a Lapine Model of Osteoarthritis: Action of Glycosaminoglycan Polysulfate Ester (GAGPS) on Proteoglycan Degrading Enzyme Activity, Hexuronate, and Cell Counts

  1986cited by this paper
• Role of synovial membrane inflammation in cartilage matrix breakdown in the Pond-Nuki dog model of osteoarthritis.

  1985cited by this paper
• In vitro metabolic response of articular cartilage segments to low levels of hydrostatic pressure.

  1985cited by this paper
• Cartilage response to mechanical force in high-density chondrocyte cultures.

  1985cited by this paper
• Fluid transport and mechanical properties of articular cartilage: a review.

  1984cited by this paper
• Effects of static and cyclic compressive loading on articular cartilage plugs in vitro.

  1984cited by this paper
• The effect of continuous mechanical pressure upon the turnover of articular cartilage proteoglycans in vitro.

  1982cited by this paper
• Glycosaminoglycan metabolism in experimental osteoarthritis caused by immobilization. The effects of different periods of immobilization and follow-up.

  1981cited by this paper
• Metabolic responses of cartilage in experimentally induced osteoarthritis.

  1981cited by this paper
• Biphasic creep and stress relaxation of articular cartilage in compression? Theory and experiments.

  1980cited by this paper
• Osteoarthritis of the knee in the rabbit produced by immobilization. Attempts to achieve a reproducible model for studies on pathogenesis and therapy.

  1979cited by this paper
• Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

  1979cited by this paper
• Balance between swelling pressure and collagen tension in normal and degenerate cartilage

  1976cited by this paper
• Biochemical changes in the cartilage of the knee in experimental and natural osteoarthritis in the dog.

  1976cited by this paper
• Response of joints to impact loading. 3. Relationship between trabecular microfractures and cartilage degeneration.

  1973cited by this paper
• Mechanical properties of articular cartilage.

  1972cited by this paper
• The interrelationship of cell density and cartilage thickness in mammalian articular cartilage.

  1971cited by this paper
• The interrelationship of cell density and cartilage thickness in mammalian articular cartilage.

  1971cited by this paper
• The distribution of collagen in human articular cartilage with some of its physiological implications.

  1970cited by this paper
• The Effects of Continuous Compression on Living Articular Cartilage: An Experimental Investigation

  1960cited by this paper

• The Impact of Mechanical Bioreactors on Human Mesenchymal Stromal Cells Utilized for Articular Cartilage Repair.

  2025cites this paper
• Predicting the heterogeneous chemo-mechano-biological degeneration of cartilage using 3-D biphasic finite elements

  2025cites this paper
• A chemo-mechano-biological modeling framework for cartilage evolving in health, disease, injury, and treatment

  2023cites this paper
• Bioreactor strategies for tissue-engineered osteochondral constructs: Advantages, present situations and future trends

  2023cites this paper
• Effect of high cyclic hydrostatic pressure on osteogenesis of mesenchymal stem cells cultured in liquefied micro-compartments

  2023cites this paper
• Experimental-analytical approach to assessing mechanosensitive cartilage blood marker kinetics in healthy adults: dose-response relationship and interrelationship of nine candidate markers [version 2; peer review: 2 approved]

  2022cites this paper
• The biomechanics of osteoarthritis in the hand: Implications and prospects for hand therapy.

  2022cites this paper
• Thoughts on cartilage tissue engineering: A 21st century perspective.

  2021cites this paper
• Effect of intermittent hydrostatic pressure on aging human chondrocyte cells

  2021cites this paper
• Regulation of chondrocyte biosynthetic activity by dynamic hydrostatic pressure: the role of TRP channels

  2021cites this paper
• Synovial Joints. Tribology, Regeneration, Regenerative Rehabilitation and Arthroplasty

  2021cites this paper
• Differential effect of frequency and duration of mechanical loading on fetal chick cartilage and bone development.

  2021cites this paper
• Experimental-analytical approach to assessing mechanosensitive cartilage blood marker kinetics in healthy adults: dose-response relationship and interrelationship of nine candidate markers

  2021cites this paper
• Intermittent Dynamic Compression Confers Anabolic Effects in Articular Cartilage

  2021cites this paper
• Loop

  2020cites this paper
• Structure and Function of Articular Cartilage

  2020cites this paper
• Functionalized water molecules confined in hydrogels for energy mitigation by assembling liquid nanofoams in micro polymeric pockets

  2020cites this paper
• LOOP

  2020cites this paper
• The effect of hydrostatic pressure on proteoglycan production in articular cartilage in vitro: a meta-analysis.

  2020cites this paper
• Loop

  2020cites this paper
• Fibrosis growth factor 23 is a promoting factor for cardiac fibrosis in the presence of transforming growth factor-β1

  2020cites this paper
• Biophysical Stimuli: A Review of Electrical and Mechanical Stimulation in Hyaline Cartilage

  2019cites this paper
• Loop

  2019cites this paper
• The effect of electric fields on hyaline cartilage: an in vitroand in silicostudy

  2019cites this paper
• Impact of Mechanobiological Perturbation in Cartilage Tissue Engineering

  2019cites this paper
• Simultaneous effects of hydrostatic pressure and dexamethasone release from electrospun fibers on inflammation-induced chondrocytes

  2019cites this paper
• Regulation of Cell Behavior by Hydrostatic Pressure.

  2019cites this paper
• Optimization of Extracellular Matrix Synthesis and Accumulation by Human Articular Chondrocytes in 3-Dimensional Construct with Repetitive Hydrostatic Pressure

  2018cites this paper
• A Guide for Using Mechanical Stimulation to Enhance Tissue-Engineered Articular Cartilage Properties

  2018influential citation
• Complex mechanical conditioning of cell‐seeded agarose constructs can influence chondrocyte biosynthetic activity

  2017cites this paper
• Articular cartilage response to a sliding load using two different-sized spherical indenters

  2017cites this paper
• Chondrogenesis of embryonic limb bud cells in micromass culture progresses rapidly to hypertrophy and is modulated by hydrostatic pressure

  2017cites this paper
• Clinical Validation of Pain Management Manipulative Therapy for Knee Osteoarthritis With the Squeeze‐Hold Technique: A Case Series

  2017cites this paper
• Running head : Biaxial loading influences chondrocytic activity

  2017cites this paper
• Introduction to Tissue Engineering

  2017cites this paper
• Upregulated sirtuin 1 by miRNA-34 a is required for smooth muscle cell differentiation from pluripotent stem cells

  2017cites this paper
• Analysis of the biological implications of the mechanical environment within the growth plate during bone development in physiological and pathological scenarios

  2016cites this paper
• Mechanobiology of TGFβ signaling in the skeleton.

  2016cites this paper
• Loss of insulin-like growth factor II imprinting is a hallmark associated with enhanced chemo/radiotherapy resistance in cancer stem cells

  2016cites this paper
• Intermittent hydrostatic pressure maintains and enhances the chondrogenic differentiation of cartilage progenitor cells cultivated in alginate beads

  2016cites this paper
• A model to study articular cartilage mechanical and biological responses to sliding and rolling loads

  2016cites this paper
• Effect of asymmetric force on the condylar cartilage, subchondral bone and collagens in the temporomandibular joints.

  2015cites this paper
• What quantitative mechanical loading stimulates in vitro cultivation best?

  2015influential citation
• Tissue-engineered cartilage: the crossroads of biomaterials, cells and stimulating factors.

  2015cites this paper
• BMSCs laden injectable amino-diethoxypropane modified alginate-chitosan hydrogel for hyaline cartilage reconstruction.

  2015cites this paper
• Environmental Factors in Cartilage Tissue Engineering

  2014cites this paper
• Approaching Inner Ear Hair Cell Regeneration Through Non-Viral Gene Delivery

  2014cites this paper
• Targeted Tissue Engineering: Enhancing Mesenchymal Stem Cell Localisation and Therapeutic Support for Cartilage Repair

  2014cites this paper
• Effects of low-intensity pulsed ultrasound on integrin-FAK-PI3K/Akt mechanochemical transduction in rabbit osteoarthritis chondrocytes.

  2014cites this paper
• The Mechanobiology of Articular Cartilage: Bearing the Burden of Osteoarthritis

  2014cites this paper
• Cyclic hydrostatic pressure promotes a stable cartilage phenotype and enhances the functional development of cartilaginous grafts engineered using multipotent stromal cells isolated from bone marrow and infrapatellar fat pad.

  2014cites this paper
• Off-Loading of Cyclic Hydrostatic Pressure Promotes Production of Extracellular Matrix by Chondrocytes

  2014cites this paper
• Physiological and excessive mechanical compression of articular cartilage activates Smad2/3P signaling.

  2014cites this paper
• Design and development of cyclic hydrostatic stress- generating machine for articular cartilage chondrocytes

  2013cites this paper
• Development of hydrodynamically engineered cartilage in response to insulin-like growth factor-1 and transforming growth factor-beta1: formation and role of a type I collagen-based fibrous capsule

  2013cites this paper
• Physeal cartilage exhibits rapid consolidation and recovery in intact knees that are physiologically loaded.

  2013cites this paper
• TRPV4 channel activation improves the tensile properties of self-assembled articular cartilage constructs.

  2013cites this paper
• Articular cartilage tissue regeneration—current research strategies and outlook for the future

  2013cites this paper
• The effects of joint immobilization on articular cartilage of the knee in previously exercised rats

  2013cites this paper
• Normal age-related viscoelastic properties of chondrons and chondrocytes isolated from rabbit knee.

  2012cites this paper
• Effect of hydrostatic pressure amplitude on chondrogenic differentiation of human adipose derived mesenchymal stem cells

  2012cites this paper
• Upregulation of matrix synthesis in chondrocyte-seeded agarose following sustained bi-axial cyclic loading

  2012cites this paper
• Biomechanics‐driven chondrogenesis: from embryo to adult

  2012cites this paper
• The effects of cyclic hydrostatic pressure on chondrocytes in an alginate substrate

  2012cites this paper
• Physical Non-Viral Gene Delivery Methods for Tissue Engineering

  2012cites this paper
• Intermittent hydrostatic pressure enhances growth factor-induced chondroinduction of human adipose-derived mesenchymal stem cells.

  2012cites this paper
• The Relationship Between Gait Mechanics and Radiographic Disease Severity in Knee Osteoarthritis

  2012cites this paper
• The Role of Physical Activity and Therapeutic Exercise in Development and Management of Knee Osteoarthritis

  2012cites this paper
• Mechanosensitive beta-Catenin Signaling Modulates Mesenchymal Stem Cell Chondrogenesis

  2012cites this paper
• Mechanical Stimulation for Functional Orthopaedic Tissue Engineering

  2012cites this paper
• Characterisation of chondrocyte matrix responses under biaxial loading / Illida Mohd Nawi

  2011cites this paper
• Spinal facet joint biomechanics and mechanotransduction in normal, injury and degenerative conditions.

  2011cites this paper
• Regional Characterization of the Knee Meniscus and Tissue Engineering with Dermal Stem Cells

  2011cites this paper
• Changes in articular cartilage mechanics with meniscectomy: A novel image-based modeling approach and comparison to patterns of OA.

  2011cites this paper
• Effects of intermittent hydrostatic pressure and BMP‐2 on osteoarthritic human chondrocyte metabolism in vitro

  2011cites this paper
• Cyclic mechanical load causes global translational arrest in articular chondrocytes: a process which is partially dependent upon PKR phosphorylation.

  2011cites this paper
• Biomechanics of the single chondrocyte and its developing extracellular matrix

  2010cites this paper
• Effect of hydrostatic pressure of various magnitudes on osteoarthritic chondrocytes exposed to IL-1beta.

  2010cites this paper
• Extended Abstracts

  2010cites this paper
• Mapping the functional properties of soft biological tissues under shear loading

  2010cites this paper
• The chondrogenic response to exercise in the proximal femur of normal and mdx mice

  2010cites this paper
• [Tissue engineering of cartilage replacement material - mechanical stimulation in the in-vitro cultivation of human chondrocytes].

  2010cites this paper
• Sensorisierter Bioreaktor mit hohem Durchsatz zur Anwendung von hydrodynamischem Druck und Scherspannungsstimuli auf Zellkulturen

  2010cites this paper
• The Effects of Voluntary Exercise on the Proximal Femur of Control and Mdx Mice

  2010cites this paper
• Tissue Engineering von Knorpelersatzgewebe – Mechanische Stimulation in der In-vitro-Kultivierung von humanen Chondrozyten

  2010cites this paper
• Dynamic hydrostatic pressure promotes differentiation of human dental pulp stem cells.

  2009cites this paper
• Evaluation of the chondral modeling theory using fe‐simulation and numeric shape optimization

  2009cites this paper
• Articular Cartilage Tissue Engineering

  2009cites this paper
• Optimizing a scaffoldless approach for cartilage tissue engineering

  2009cites this paper
• The role of tissue engineering in articular cartilage repair and regeneration.

  2009cites this paper
• Technical strategies to improve tissue engineering of cartilage-carrier-constructs.

  2009cites this paper
• Effects of hydrostatic pressure on leporine meniscus cell-seeded PLLA scaffolds.

  2009cites this paper
• Impact loading and functional tissue engineering of articular cartilage

  2009cites this paper
• Engineering the Knee Meniscus

  2009cites this paper
• Hydrostatic Pressure in Articular Cartilage Tissue Engineering: From Chondrocytes to Tissue Regeneration

  2009cites this paper
• TRANSPORT PROPERTIES OF CARTILAGINOUS TISSUES.

  2009cites this paper
• Effects of TGF-beta1 and hydrostatic pressure on meniscus cell-seeded scaffolds.

  2009cites this paper
• A novel biomimetic polymer scaffold design enhances bone ingrowth.

  2009cites this paper
• Human cells derived from degenerate intervertebral discs respond differently to those derived from non-degenerate intervertebral discs following application of dynamic hydrostatic pressure

  2008cites this paper
• Title Synergistic and additive effects of hydrostatic pressure and growth factors on tissue formation Permalink

  2008cites this paper