LUPA: a European initiative taking advantage of the canine genome architecture for unravelling complex disorders in both human and dogs.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  The Veterinary Journal

• Publication date

  2011-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.tvjl.2011.06.013PMID 21752675
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Locus on Chromosome 5 Is Associated with Dilated Cardiomyopathy in Doberman Pinschers

  2011cited by this paper
• CCDC39 is required for assembly of inner dynein arms and the dynein regulatory complex and for normal ciliary motility in humans and dogs

  2011cited by this paper
• A Novel Unstable Duplication Upstream of HAS2 Predisposes to a Breed-Defining Skin Phenotype and a Periodic Fever Syndrome in Chinese Shar-Pei Dogs

  2011cited by this paper
• Identification of 2 loci associated with development of myxomatous mitral valve disease in Cavalier King Charles Spaniels.

  2011cited by this paper
• LGI2 Truncation Causes a Remitting Focal Epilepsy in Dogs

  2011cited by this paper
• Genome-wide association study in Dachshund: identification of a major locus affecting intervertebral disc calcification.

  2011cited by this paper
• GCTA: a tool for genome-wide complex trait analysis.

  2011cited by this paper
• A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis

  2010cited by this paper
• A Simple Genetic Architecture Underlies Morphological Variation in Dogs

  2010cited by this paper
• Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex

  2010cited by this paper
• Prevalence of dilated cardiomyopathy in Doberman Pinschers in various age groups.

  2010cited by this paper
• Localization of Canine Brachycephaly Using an Across Breed Mapping Approach

  2010cited by this paper
• From the Cover: Tracking footprints of artificial selection in the dog genome

  2010cited by this paper
• Coat Variation in the Domestic Dog Is Governed by Variants in Three Genes

  2009cited by this paper
• Revisiting the missing protein-coding gene catalog of the domestic dog

  2009cited by this paper
• Genetic mapping of fixed phenotypes: disease frequency as a breed characteristic.

  2009cited by this paper
• Inherited defects in pedigree dogs. Part 1: disorders related to breed standards.

  2009cited by this paper
• Single-Nucleotide-Polymorphism-Based Association Mapping of Dog Stereotypes

  2008cited by this paper
• Leader of the pack: gene mapping in dogs and other model organisms

  2008cited by this paper
• A cis-acting regulatory mutation causes premature hair graying and susceptibility to melanoma in the horse

  2008cited by this paper
• The breeding of pedigree dogs: time for strong leadership.

  2008cited by this paper
• Efficient Control of Population Structure in Model Organism Association Mapping

  2008cited by this paper
• A prospective genetic evaluation of familial dilated cardiomyopathy in the Doberman pinscher.

  2007cited by this paper
• Understanding hereditary diseases using the dog and human as companion model systems

  2007cited by this paper
• GenABEL: an R library for genome-wide association analysis

  2007cited by this paper
• Efficient mapping of mendelian traits in dogs through genome-wide association

  2007cited by this paper
• Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs

  2007cited by this paper
• Benign familial juvenile epilepsy in Lagotto Romagnolo dogs.

  2007cited by this paper
• PLINK: a tool set for whole-genome association and population-based linkage analyses.

  2007cited by this paper
• Principal components analysis corrects for stratification in genome-wide association studies

  2006cited by this paper
• Canine Genomics and Genetics: Running with the Pack

  2005cited by this paper
• Genome sequence, comparative analysis and haplotype structure of the domestic dog

  2005cited by this paper
• Extensive and breed-specific linkage disequilibrium in Canis familiaris.

  2004cited by this paper
• Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor

  1996cited by this paper

• Pet owners’ perspectives on veterinary biobanking in Latvia: Awareness, motivations, ethical concerns, and willingness to participate

  2025cites this paper
• Association of the TTN, PDK4, and RNF207 mutations with dilated cardiomyopathy in Dobermanns from the United Kingdom

  2025cites this paper
• Seroprevalence of zoonotic pathogens and related haematological and biochemical profiles in Fonni's dogs in rural conditions.

  2025cites this paper
• Ancient dog introgression into the Iberian wolf genome may have facilitated adaptation to human-dominated landscapes

  2025cites this paper
• Fasting triglyceride concentrations are associated with markers of lipid metabolism and glucose homeostasis in healthy, non-obese dogs in lean and overweight condition

  2024cites this paper
• Mammary gland, skin and soft tissue tumors in pet cats: findings of the feline tumors collected from 2002 to 2022

  2024cites this paper
• EPILEPSIA IDIOPATICA FOCAL CON CRISIS MOTORAS EN 50 CANICHES EN ARGENTINA: CARACTERIZACION ELECTROCLINICA Y RESPUESTA A LA TERAPIA

  2024cites this paper
• Association of the FTO gene with obesity and cancer in dogs

  2023cites this paper
• Banking on a new understanding: translational opportunities from veterinary biobanks

  2023cites this paper
• Genomic and Transcriptomic Characterization of Atypical Recurrent Flank Alopecia in the Cesky Fousek

  2022cites this paper
• In vitro anticancer effects of alpelisib against PIK3CA-mutated canine hemangiosarcoma cell lines

  2022cites this paper
• Improving Osteosarcoma Treatment: Comparative Oncology in Action

  2022cites this paper
• Clinical characterization of epileptic seizures in Pomeranians with idiopathic epilepsy or epilepsy of unknown cause

  2022cites this paper
• The beneficial role of companion animals in translational pain research

  2022cites this paper
• A reduced SNP panel to trace gene flow across southern European wolf populations and detect hybridization with other Canis taxa

  2022cites this paper
• LncRNAs in domesticated animals: from dog to livestock species

  2021cites this paper
• A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats

  2021cites this paper
• OptM: estimating the optimal number of migration edges on population trees using Treemix

  2021cites this paper
• Improving the resolution of canine genome-wide association studies using genotype imputation: A study of two breeds

  2021cites this paper
• Estimating Admixture at the Population Scale: Taking Imperfect Detectability and Uncertainty in Hybrid Classification Seriously

  2021cites this paper
• Targeted next-generation sequencing of candidate regions identified by GWAS revealed SNPs associated with IBD in GSDs

  2021cites this paper
• Web resource on available DNA variant tests for hereditary diseases and genetic predispositions in dogs and cats: An Update

  2021cites this paper
• COMMD1 Exemplifies the Power of Inbred Dogs to Dissect Genetic Causes of Rare Copper-Related Disorders

  2021cites this paper
• Genetics of canine diabetes mellitus part 2: Current understanding and future directions.

  2021cites this paper
• A missense variant in IFT122 associated with a canine model of retinitis pigmentosa

  2021cites this paper
• Comparison of inherited neural tube defects in companion animals and livestock

  2020cites this paper
• It’s complex : studies on the genetics of canine hip dysplasia

  2020cites this paper
• A modern look at the molecular-biological mechanisms of breast tumours in dogs

  2020cites this paper
• Genome wide association study of 40 clinical measurements in eight dog breeds

  2020cites this paper
• A putative silencer variant in a spontaneous canine model of retinitis pigmentosa

  2020cites this paper
• Genetic Characterization of the Yugoslavian Shepherd Dog – Sharplanina, a Livestock Guard Dog from the Western Balkans

  2020cites this paper
• Chapitre 18. L’apport de la génétique dans la compréhension des comportements canins et pour l’éducation du chien

  2020cites this paper
• DNA methylation aging clocks: challenges and recommendations

  2019cites this paper
• Highly Heritable and Functionally Relevant Breed Differences in Dog Behavior

  2019cites this paper
• The potential of translational research in dogs in human medicine

  2019cites this paper
• A synonymous germline variant in a gene encoding a cell adhesion molecule is associated with cutaneous mast cell tumour development in Labrador and Golden Retrievers

  2019cites this paper
• The Dog Model in the Spotlight: Legacy of a Trustful Cooperation

  2019cites this paper
• Pectinate ligament dysplasia and primary glaucoma in dogs : investigating prevalence and identifying genetic risk factors

  2019cites this paper
• Wolf outside, dog inside? The genomic make-up of the Czechoslovakian Wolfdog

  2018cites this paper
• Strengths and Weaknesses of Pre-Clinical Models for Human Melanoma Treatment: Dawn of Dogs’ Revolution for Immunotherapy

  2018cites this paper
• Genome-Wide Analysis of SNPs Is Consistent with No Domestic Dog Ancestry in the Endangered Mexican Wolf (Canis lupus baileyi)

  2018cites this paper
• Whole‐Genome Sequencing of African Dogs Provides Insights into Adaptations against Tropical Parasites

  2018cites this paper
• Interbreed variation in serum serotonin (5-hydroxytryptamine) concentration in healthy dogs.

  2018cites this paper
• PETscan: measuring incidence of disease phenotypes to prioritize genetic studies in companion animals.

  2018cites this paper
• Canine immune-mediated disease Studies of epidemiology , genetics , and autoantibodies

  2018cites this paper
• Interbreed variation of biomarkers of lipid and glucose metabolism in dogs

  2018cites this paper
• Analyses génétiques et génomiques de maladies neurologiques chez le chien comme modèle de maladies rares humaines

  2018cites this paper
• FEELnc: a tool for long non-coding RNA annotation and its application to the dog transcriptome

  2017cites this paper
• The importance of dogs for comparative pathology and genetics: Examples of shared resources and programmes

  2017cites this paper
• The Role and Effectiveness of Regulation of Dog Breeding in Australia

  2017cites this paper
• Developmental Anomalies in Domestic Mammals and the One Health Concept

  2017cites this paper
• ADAM23 is a common risk gene for canine idiopathic epilepsy

  2017cites this paper
• Border Terriers under primary veterinary care in England: demography and disorders

  2017cites this paper
• Disentangling timing of admixture , patterns of introgression and phenotypic indicators in a hybridizing wolf population RUNNING

  2017cites this paper
• CSPG4: a prototype oncoantigen for translational immunotherapy studies

  2017cites this paper
• Disentangling Timing of Admixture, Patterns of Introgression, and Phenotypic Indicators in a Hybridizing Wolf Population

  2017cites this paper
• Evaluation of the genetic basis of primary hypoadrenocorticism in Standard Poodles using SNP array genotyping and whole-genome sequencing

  2017cites this paper
• The companion dog as a unique translational model for aging.

  2017cites this paper
• Serum Biochemical Phenotypes in the Domestic Dog

  2016cites this paper
• Genetics of dog behavior

  2016cites this paper
• Animal Models for Translational Cancer Immunotherapy Studies

  2016cites this paper
• Contributions to biostatistics: categorical data analysis, data modeling and statistical inference

  2016cites this paper
• Domesticated Animal Biobanking: Land of Opportunity

  2016cites this paper
• FEELnc: A tool for Long non-coding RNAs annotation and its application to the dog transcriptome

  2016cites this paper
• Complex disease and phenotype mapping in the domestic dog

  2016cites this paper
• A Point Mutation in a lincRNA Upstream of GDNF Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies

  2016cites this paper
• Comparative Analysis of Genome Diversity in Bullmastiff Dogs

  2016cites this paper
• SMILE: A novel dissimilarity-based procedure for detecting sparse-specific profiles in sparse contingency tables

  2016cites this paper
• Effect of Breed on Plasma Endothelin‐1 Concentration, Plasma Renin Activity, and Serum Cortisol Concentration in Healthy Dogs

  2016cites this paper
• The canine era: the rise of a biomedical model.

  2016cites this paper
• Whole-genome sequence, SNP chips and pedigree structure: building demographic profiles in domestic dog breeds to optimize genetic-trait mapping

  2016cites this paper
• Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1278 Complex Trait Genetics Beyond Additivity

  2016cites this paper
• A general intelligence factor in dogs

  2016influential citation
• From Sanger to NGS: Detecting MHC (Major Histocompatibility Complex) Class II and OR (Olfactory Receptors) Genetic Variability in Italian Wolves (Canis Lupus) and relative Canids

  2016cites this paper
• Dog Models of Naturally Occurring Cancer

  2016cites this paper
• The importance of comparative oncology in translational medicine

  2015cites this paper
• Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency

  2015cites this paper
• Canine whole exome sequencing: hip, hip, hurray?

  2015cites this paper
• Genetic management of Dutch golden retriever dogs with a simulation tool.

  2015cites this paper
• Identification of a common risk haplotype for canine idiopathic epilepsy in the ADAM23 gene

  2015cites this paper
• Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease

  2015cites this paper
• Animal Models in Biomedical Research

  2015cites this paper
• Reference genes for reverse transcription quantitative PCR in canine brain tissue

  2015cites this paper
• The Shepherds’ Tale: A Genome-Wide Study across 9 Dog Breeds Implicates Two Loci in the Regulation of Fructosamine Serum Concentration in Belgian Shepherds

  2015cites this paper
• Title Identification of a common risk haplotype for canine idiopathic epilepsy in the ADAM 23 gene

  2015cites this paper
• First evidence of hybridization between golden jackal (Canis aureus) and domestic dog (Canis familiaris) as revealed by genetic markers

  2015cites this paper
• An Improved Canine Genome and a Comprehensive Catalogue of Coding Genes and Non-Coding Transcripts

  2014cites this paper
• Development and performance of a targeted whole exome sequencing enrichment kit for the dog (Canis Familiaris Build 3.1)

  2014cites this paper
• Setting the One Health Agenda and the Human-Companion Animal Bond

  2014cites this paper
• Conservation Genomics of the Endangered Mexican Wolf and De Novo SNP Marker Development in Pumas using Next-Generation Sequencing

  2014cites this paper
• Genetic basis of cranial cruciate ligament rupture (CCLR) in dogs

  2014cites this paper
• Effect of a Leucine/Pyridoxine Nutraceutical on Energy Metabolism and Satiety in Lean and Obese Dogs

  2014cites this paper
• Dog as a model in studies on human hereditary diseases and their gene therapy.

  2014cites this paper
• Cardiovascular endocrinology in naturally occurring canine and feline models

  2014cites this paper
• CSPG4-Specific Immunity and Survival Prolongation in Dogs with Oral Malignant Melanoma Immunized with Human CSPG4 DNA

  2014cites this paper
• Breed Differences in Natriuretic Peptides in Healthy Dogs

  2014cites this paper
• Naturally occurring cancers in dogs: insights for translational genetics and medicine.

  2014cites this paper
• A Genome-Wide Association Study Points out the Causal Implication of SOX9 in the Sex-Reversal Phenotype in XX Pigs

  2013cites this paper
• Inherited epilepsy in dogs.

  2013cites this paper
• Dog obesity--the need for identifying predisposing genetic markers.

  2013cites this paper