Influenza Pandemics of the 20th Century

Influenza A virus infection created confusion in distinguishing true pandemics, pseudopandemics, and epidemics.

• Publication year

  2006

• Venue

  Emerging Infectious Diseases

• Publication date

  2006-01-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.3201/eid1201.051254PMID 16494710PMCID 3291411
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1982cited by this paper
• Epidemiology of influenza in man.

  1979cited by this paper
• Effect of neuraminidase antibody on Hong Kong influenza.

  1973cited by this paper
• Protection against Hong Kong influneza by adjuvant vaccine containing A2-Ann Arbor-67.

  1969cited by this paper
• Independent variation in nature of hemagglutinin and neuraminidase antigens of influenza virus: distinctiveness of hemagglutinin antigen of Hong Kong-68 virus.

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• Future influenza vaccines and the use of genetic recombinants.

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  1961cited by this paper
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  1959cited by this paper
• Studies on influenza in the pandemic of 1957-1958. II. Pulmonary complications of influenza.

  1959cited by this paper
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  1958cited by this paper
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