Sequence differences between alpha1C and alpha1S Ca2+ channel subunits reveal structural determinants of a guarded and modulated benzothiazepine receptor.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Biological Chemistry

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 10037699
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Calculation of concentrations of equilibrium components in an in vitro activity test of vancomycin antibiotics and the possible mode of action.

  1998cited by this paper
• Structural basis of drug binding to L Ca2+ channels.

  1998cited by this paper
• Ca2+ channel block and inactivation: common molecular determinants.

  1998cited by this paper
• Inhibition of recombinant Ca2+ channels by benzothiazepines and phenylalkylamines: class-specific pharmacology and underlying molecular determinants.

  1997cited by this paper
• Transfer of the high affinity dihydropyridine sensitivity from L-type To non-L-type calcium channel.

  1997cited by this paper
• Analysis of the Dihydropyridine Receptor Site ofl-type Calcium Channels by Alanine-scanning Mutagenesis*

  1997cited by this paper
• Molecular determinants of drug binding and action on L-type calcium channels.

  1997cited by this paper
• Molecular mechanism of use-dependent calcium channel block by phenylalkylamines: role of inactivation.

  1997cited by this paper
• Calcium channel block by (-)devapamil is affected by the sequence environment and composition of the phenylalkylamine receptor site.

  1997cited by this paper
• Molecular Studies on the Voltage Dependence of Dihydropyridine Action on L-type Ca2+ Channels

  1997cited by this paper
• Nine L-type Amino Acid Residues Confer Full 1,4-Dihydropyridine Sensitivity to the Neuronal Calcium Channel α1ASubunit

  1997cited by this paper
• N-type inactivation and the S4-S5 region of the Shaker K+ channel

  1996cited by this paper
• Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels.

  1996cited by this paper
• Identification of Benz(othi)azepine-binding Regions within L-type Calcium Channel α1 Subunits*

  1996cited by this paper
• Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A.

  1996cited by this paper
• Two Amino Acid Residues in the IIIS5 Segment of L-Type Calcium Channels Differentially Contribute to 1,4-Dihydropyridine Sensitivity*

  1996cited by this paper
• The IVS6 segment of the L‐type calcium channel is critical for the action of dihydropyridines and phenylalkylamines.

  1996cited by this paper
• Molecular Determinants of High Affinity Dihydropyridine Binding in L-type Calcium Channels (*)

  1996cited by this paper
• Transfer of High Sensitivity for Benzothiazepines from L-type to Class A (BI) Calcium Channels*

  1996cited by this paper
• Extra‐ and intracellular action of quaternary devapamil on muscle L‐type Ca2+‐channels

  1996cited by this paper
• Molecular Determinants of High Affinity Phenylalkylamine Block of L-type Calcium Channels (*)

  1995cited by this paper
• The naming of voltage-gated calcium channels.

  1994cited by this paper
• Extracellular localization of the benzothiazepine binding domain of L-type Ca2+ channels.

  1993cited by this paper
• Conformationally constrained calcium channel blockers: novel mimics of 1-benzazepin-2-ones.

  1993cited by this paper
• Primary structure and functional expression from complementary DNA of a brain calcium channel.

  1991cited by this paper
• Calcium channels from Cyprinus carpio skeletal muscle.

  1991cited by this paper
• Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

  1989cited by this paper
• Primary structure of the receptor for calcium channel blockers from skeletal muscle

  1987cited by this paper
• Phasic ion channel blockade. A kinetic model and parameter estimation procedure.

  1985cited by this paper
• Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells

  1983cited by this paper
• Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane?

  1982cited by this paper
• Local anesthetics: hydrophilic and hydrophobic pathways for the drug- receptor reaction

  1977cited by this paper

• T1143 Essential for CaV1.2 Inhibition by Diltiazem.

  2021cites this paper
• Selective pressure modulation of synaptic voltage‐dependent calcium channels—involvement in HPNS mechanism

  2016cites this paper
• Selective modulation of cellular voltage-dependent calcium channels by hyperbaric pressure—a suggested HPNS partial mechanism

  2014cites this paper
• Interaction of diltiazem with an intracellularly accessible binding site on CaV1.2

  2011cites this paper
• Characterization of L-type Calcium Channel Binding-Site of a new class of Calcium modulators by a Multidisciplinary approach

  2009cites this paper
• Inhibition of the Cardiac L-Type Calcium Channel Current by Antidepressant Drugs

  2008cites this paper
• Molecular Modeling of Benzothiazepine Binding in the L-type Calcium Channel*

  2008cites this paper
• Competitive and Cooperative Effects of Bay K8644 on the L-Type Calcium Channel Current Inhibition by Calcium Channel Antagonists

  2007cites this paper
• Diltiazem analogues: the last ten years on structure activity relationships.

  2007cites this paper
• A novel molecular inactivation determinant of voltage-gated CaV1.2 L-type Ca2+ channel.

  2006cites this paper
• Calcium channel inactivation: possible role in signal transduction and Ca2+ signaling.

  2005cites this paper
• Modulation of the Voltage Sensor of L-type Ca2+ Channels by Intracellular Ca2+

  2004cites this paper
• A non-voltage-gated calcium channel with L-type characteristics activated by B cell receptor ligation.

  2003cites this paper
• Molecular determinants of Ca2+ potentiation of diltiazem block and Ca2+-dependent inactivation in the pore region of cav1.2.

  2003cites this paper
• Slow deactivation and U-shaped inactivation properties in cloned Cav1.2b channels in Chinese hamster ovary cells.

  2003cites this paper
• Molecular Determinants of Ca 2 Potentiation of Diltiazem Block and Ca 2-Dependent Inactivation in the Pore Region of Cav 1 . 2

  2003cites this paper
• Molecular Determinants of Voltage-dependent Slow Inactivation of the Ca2+ Channel*

  2002cites this paper
• The Role of Region IVS5 of the Human Cardiac Calcium Channel in Establishing Inactivated Channel Conformation

  2002cites this paper
• Inactivation determinants in segment IIIS6 of Cav3.1

  2001cites this paper
• Amino Acids in Segment IVS6 and β-Subunit Interaction Support Distinct Conformational Changes during Cav2.1 Inactivation*

  2001cites this paper
• Voltage‐dependent acceleration of Cav1.2 channel current decay by (+)‐ and (−)‐isradipine

  2001cites this paper
• On the Role of Ca2+- and Voltage-Dependent Inactivation in Cav1.2 Sensitivity for the Phenylalkylamine (-)Gallopamil

  2001cites this paper
• Molecular Mechanism of Calcium Channel Block by Isradipine

  2000cites this paper
• New molecular determinant for inactivation of the human L-type alpha1C Ca2+ channel.

  2000cites this paper
• New Molecular Determinant for Inactivation of the Human L-Type α1C Ca2+ Channel

  2000cites this paper
• Molecular determinants of inactivation in voltage‐gated Ca2+ channels

  2000cites this paper
• Inactivation determinant in the I-II loop of the Ca2+ channel alpha1-subunit and beta-subunit interaction affect sensitivity for the phenylalkylamine (-)gallopamil.

  1999cites this paper