Expression of CCR9 beta-chemokine receptor is modulated in thymocyte differentiation and is selectively maintained in CD8(+) T cells from secondary lymphoid organs.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Blood

• Publication date

  2001-02-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/BLOOD.V97.4.850PMID 11159507
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Thymus

  2012cited by this paper
• International union of pharmacology. XXII. Nomenclature for chemokine receptors.

  2000cited by this paper
• Developmental Switches in Chemokine Response Profiles during B Cell Differentiation and Maturation

  2000cited by this paper
• The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double‐ and single‐positive thymocytes expressing the TECK receptor CCR9

  2000cited by this paper
• Murine CCR9, a Chemokine Receptor for Thymus-Expressed Chemokine That Is Up-Regulated Following Pre-TCR Signaling1

  2000cited by this paper
• Chemokines: a new classification system and their role in immunity.

  2000cited by this paper
• CD69 expression discriminates MHC-dependent and -independent stages of thymocyte positive selection.

  1999cited by this paper
• CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.

  1999cited by this paper
• Human G Protein–Coupled Receptor Gpr-9-6/Cc Chemokine Receptor 9 Is Selectively Expressed on Intestinal Homing T Lymphocytes, Mucosal Lymphocytes, and Thymocytes and Is Required for Thymus-Expressed Chemokine–Mediated Chemotaxis

  1999cited by this paper
• Pertussis toxin-sensitive signal controls the trafficking of thymocytes across the corticomedullary junction in the thymus.

  1999cited by this paper
• Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK.

  1999cited by this paper
• Factors regulating stem cell recruitment to the fetal thymus.

  1999cited by this paper
• Cutting edge: developmental switches in chemokine responses during T cell maturation.

  1999cited by this paper
• Macrophage inflammatory protein-1β induces migration and activation of human thymocytes

  1998cited by this paper
• Changes in thymic function with age and during the treatment of HIV infection

  1998cited by this paper
• Differential chemotactic behavior of developing T cells in response to thymic chemokines.

  1998cited by this paper
• Chemokines--chemotactic cytokines that mediate inflammation.

  1998cited by this paper
• Macrophage inflammatory protein-1beta induces migration and activation of human thymocytes.

  1998cited by this paper
• TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development.

  1997cited by this paper
• The Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood

  1997cited by this paper
• Chemokines.

  1997cited by this paper
• Recent thymic emigrants are distinct from most medullary thymocytes

  1997cited by this paper
• The thymic microenvironment.

  1993cited by this paper
• Development in the thymus: it takes two to tango.

  1993cited by this paper
• A pertussis toxin‐sensitive process controls thymocyte emigration

  1991cited by this paper
• Towards an integrated view of thymopoiesis.

  1991cited by this paper
• Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP‐ribosyltransferase.

  1990cited by this paper

• Chemokine receptors in GtoPdb v.2025.1

  2025cites this paper
• Unveiling CCR9 and CCL13 as immune biomarkers and therapeutic targets in thymoma

  2025cites this paper
• Chemokine receptors in GtoPdb v.2025.3

  2025cites this paper
• Advances in cancer diagnosis and therapy by alginate-based multifunctional hydrogels: A review.

  2024cites this paper
• A spatial human thymus cell atlas mapped to a continuous tissue axis

  2024cites this paper
• Developmental trajectory of unconventional T cells of the cynomolgus macaque thymus

  2024cites this paper
• Characterization of pre- and on-treatment soluble immune mediators and the tumor microenvironment in NSCLC patients receiving PD-1/L1 inhibitor monotherapy

  2024cites this paper
• Promoting the Recruitment, Engagement, and Reinvigoration of Effector T Cells via an Injectable Hydrogel with a Supramolecular Binding Capability for Cancer Immunotherapy

  2023cites this paper
• Chemokine receptors in GtoPdb v.2023.1 Chemokine receptors in GtoPdb v.2023.1

  2023cites this paper
• A spatial human thymus cell atlas mapped to a continuous tissue axis

  2023cites this paper
• Investigating underlying human immunity genes, implicated diseases and their relationship to COVID-19

  2022cites this paper
• Therapeutic potential of an anti-CCR9 mAb evidenced in xenografts of human CCR9+ tumors

  2022cites this paper
• Donor T cell DNMT3a regulates alloreactivity in mouse models of hematopoietic stem cell transplantation

  2022cites this paper
• Anti-CCR9 Chimeric Antigen Receptor T cells for T Cell Acute Lymphoblastic Leukemia.

  2022cites this paper
• Tumor microenvironment immune-related lncRNA signature for patients with melanoma

  2021cites this paper
• CCL25 Signaling in the Tumor Microenvironment.

  2021cites this paper
• CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of Receptors CCR5, CCR6, CCR7, CCR8, CCR9, and CCR10 Ligands

  2020cites this paper
• Role of Chemokines and Chemokine Receptors in Infectious Diseases and Targeting Strategies

  2019cites this paper
• CC chemokines are differentially expressed in Breast Cancer and are associated with disparity in overall survival

  2019cites this paper
• Concepts of GPCR‐controlled navigation in the immune system

  2019cites this paper
• Chemokine receptors (version 2019.5) in the IUPHAR/BPS Guide to Pharmacology Database

  2019cites this paper
• Chemokine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

  2019cites this paper
• 92R Monoclonal Antibody Inhibits Human CCR9+ Leukemia Cells Growth in NSG Mice Xenografts

  2018cites this paper
• University Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional T-cell Development

  2017cites this paper
• Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell Development

  2017cites this paper
• CCR9 AND CCR7 are overexpressed in CD4–CD8– thymocytes of myasthenia gravis patients

  2017cites this paper
• Corrigendum: A draft network of ligand-receptor-mediated multicellular signalling in human

  2016cites this paper
• CCR9 Is a Key Regulator of Early Phases of Allergic Airway Inflammation

  2016influential citation
• Abrogation of CC chemokine receptor 9 ameliorates ventricular remodeling in mice after myocardial infarction

  2016cites this paper
• Leukocyte homing, fate, and function are controlled by retinoic acid.

  2015cites this paper
• A draft network of ligand–receptor-mediated multicellular signalling in human

  2015cites this paper
• Renin-angiotensin system contributes to naive T-cell migration in vivo.

  2015cites this paper
• Germinal Center B Cell Fitness Cells and Follicular Dendritic Cells Influence Integrin-Mediated Interactions between B

  2014cites this paper
• Characteristics and functions of thymic exosomes in human and mouse

  2014cites this paper
• Antitumor effects of a monoclonal antibody to human CCR9 in leukemia cell xenografts

  2014cites this paper
• Relevance of the activation and migration patterns of CD8 T cells for the development of immune-mediated liver injury

  2014cites this paper
• Influence of CD8 T cell priming in liver and gut on the enterohepatic circulation.

  2014cites this paper
• Integrin-Mediated Interactions between B Cells and Follicular Dendritic Cells Influence Germinal Center B Cell Fitness

  2014cites this paper
• CXCR3-Expressing Microglia Neurotoxic CCR9- or Neurosupportive Different Neurotropic Pathogens Elicit

  2013cites this paper
• CCR9-dependent and -independent homing to the small intestine primed CD4+ T cells display - Gut-associated lymphoid tissue

  2013cites this paper
• intraepithelial lymphocytes + gut δ γ early T- and B-cell development and a reduction in T-cell receptor Mice lacking the CCR9 CC-chemokine receptor show a mild impairment of

  2013cites this paper
• Codon usage and coevolution of the large and small subunits of Ribulose-1,5-bisphosphate carboxylase/oxygenase: Codon usage and coevolution of RuBisCO subunits

  2013cites this paper
• Codon usage and coevolution of the large and small subunits of ribulose‐1,5‐bisphosphate carboxylase/oxygenase

  2013cites this paper
• C‐C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice

  2013cites this paper
• AgingChemokine Receptor Expression in

  2013cites this paper
• Characterization of CCR9 expression and thymus-expressed chemokine responsiveness of the murine thymus, spleen and mesenteric lymph node.

  2012cites this paper
• Pathogenic impact of immune-related cells in Batten disease

  2012cites this paper
• Signal integration and crosstalk during thymocyte migration and emigration

  2011cites this paper
• CCL 25 mediates migration , invasion and matrix metalloproteinase expression by breast cancer cells in a CCR 9-dependent fashion

  2011cites this paper
• Finding their niche: chemokines directing cell migration in the thymus

  2011cites this paper
• Differential Functions Of CCR9- Or CXCR3-Expressing Microglia

  2011cites this paper
• Characterization of Gut‐Derived Intraepithelial Lymphocyte (IEL) Residing in Human Papillomavirus (HPV)‐Infected Intraepithelial Neoplastic Lesions

  2011cites this paper
• CCL25 mediates migration, invasion and matrix metalloproteinase expression by breast cancer cells in a CCR9-dependent fashion.

  2011cites this paper
• Abnormal regulation of chemokine TECK and its receptor CCR9 in the endometriotic milieu is involved in pathogenesis of endometriosis by way of enhancing invasiveness of endometrial stromal cells

  2010cites this paper
• GSK-1605786, a selective small-molecule antagonist of the CCR9 chemokine receptor for the treatment of Crohn's disease.

  2010cites this paper
• T Cells ''Default'' Generation of Neonatal Regulatory

  2010cites this paper
• Ezrin is a key molecule in the metastasis of MOLT4 cells induced by CCL25/CCR9.

  2010cites this paper
• The thymus microenvironment in regulating thymocyte differentiation

  2010cites this paper
• “Default” Generation of Neonatal Regulatory T Cells

  2010cites this paper
• Retinoic acid production by intestinal dendritic cells and its role in T-cell trafficking.

  2009cites this paper
• LYMPHOPOETIC FUNCTION OF THE THYMUS

  2009cites this paper
• Retinoic acid receptor signaling levels and antigen dose regulate gut homing receptor expression on CD8+ T cells

  2008cites this paper
• Homing imprinting and immunomodulation in the gut: role of dendritic cells and retinoids.

  2008cites this paper
• Involvement of CCR9 at multiple stages of adult T lymphopoiesis

  2008cites this paper
• Retinoic acid receptor signaling levels and antigen dose regulate gut homing receptor expression

  2008cites this paper
• CCR9 Homes Metastatic Melanoma Cells to the Small Bowel

  2008cites this paper
• ENHANCED ACUTE RESPONSES IN AN EXPERIMENTAL EXPOSURE MODEL TO BIOMASS SMOKE INHALATION IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE

  2008cites this paper
• CCR9 Chemokine Receptor

  2008cites this paper
• Intracellular signaling required for CCL25-stimulated T cell adhesion mediated by the integrin alpha4beta1.

  2007cites this paper
• Chemokines in Trafficking of Hematopoietic Stem and Progenitor Cells and Hematopoiesis

  2007cites this paper
• Intracellular signaling required for CCL25‐stimulated T cell adhesion mediated by the integrin α4β1

  2007influential citation
• Aberrant T‐cell ontogeny and defective thymocyte and colonic T‐cell chemotactic migration in colitis‐prone Gαi2‐deficient mice

  2007cites this paper
• Characteristics and Consequences of Thymic Involution in Inflammatory Bowel Disease. Experimental studies in Gαi2-deficient and DSS-induced Colitis as well as in IBD patients

  2007cites this paper
• Generation of gut‐homing T cells and their localization to the small intestinal mucosa

  2007influential citation
• Different Neurotropic Pathogens Elicit Neurotoxic CCR9- or Neurosupportive CXCR3-Expressing Microglia1

  2006cites this paper
• Anti-Epo receptor antibodies do not predict Epo receptor expression.

  2006cites this paper
• Tissue-tropic effector T cells: generation and targeting opportunities

  2006cites this paper
• Emergent Dynamics of Thymocyte Development and Lineage Determination

  2006cites this paper
• Role of CCL25/CCR9 in immune homeostasis and disease

  2006cites this paper
• Premature Expression of Chemokine Receptor CCR9 Impairs T Cell Development

  2006influential citation
• Gut-associated lymphoid tissue-primed CD4+ T cells display CCR9-dependent and -independent homing to the small intestine.

  2006cites this paper
• T-cell homing specificity and plasticity: new concepts and future challenges.

  2006cites this paper
• Journey through the thymus: stromal guides for T-cell development and selection

  2006cites this paper
• Specificity and plasticity of memory lymphocyte migration.

  2006influential citation
• Trafficking on serpentines: molecular insight on how maturating T cells find their winding paths in the thymus

  2006cites this paper
• Complementary contribution of CD4 and CD8 T lymphocytes to T-cell infiltration of the intact and the degenerative spinal cord.

  2005cites this paper
• The role of CCL21 in recruitment of T-precursor cells to fetal thymi.

  2005cites this paper
• Reciprocal and dynamic control of CD8 T cell homing by dendritic cells from skin- and gut-associated lymphoid tissues

  2005cites this paper
• Essential role for CD103 in the T cell–mediated regulation of experimental colitis

  2005cites this paper
• Functional specialization of gut CD103 dendritic cells in the regulation of tissue-selective T cell homing

  2005cites this paper
• Tracking thymocyte migration in situ.

  2005cites this paper
• Chemokines and Their Receptors in Hematopoietic Cell Development and Functioning

  2005cites this paper
• Expression and Functional Role of CCR9 in Prostate Cancer Cell Migration and Invasion

  2004cites this paper
• Signaling via the AHR leads to enhanced usage of CD44v10 by murine fetal thymic emigrants: possible role for CD44 in emigration.

  2004cites this paper
• Impaired chemokine‐induced migration during T‐cell development in the absence of Jak 3

  2004cites this paper
• CCL25/CCR9 promotes the induction and function of CD103 on intestinal intraepithelial lymphocytes

  2004cites this paper
• Integrin-Positive and CC ChemokineE α Recent Thymic Emigrants are + Murine CD 8

  2004cites this paper
• Role of CCL21 in Recruitment of T Precursor Cells to Fetal Thymus

  2004cites this paper
• Homing of immature thymocytes to the subcapsular microenvironment within the thymus is not an absolute requirement for T cell development

  2004cites this paper
• Molecular mechanisms governing thymocyte migration: combined role of chemokines and extracellular matrix

  2004cites this paper