Engineered bacteria in which motility is reduced by local cell density generate periodic stripes of high and low density when spotted on agar plates. We study theoretically the origin and mechanism of this process in a kinetic model that includes growth and density-suppressed motility of the cells. The spreading of a region of immotile cells into an initially cell-free region is analyzed. From the calculated front profile we provide an analytic ansatz to determine the phase boundary between the stripe and the no-stripe phases. The influence of various parameters on the phase boundary is discussed.
Stripe formation in bacterial systems with density-suppressed motility.
Xiongfei Fu,Lei-Han Tang,Chenli Liu,Jian-Dong Huang,T. Hwa,P. Lenz
Published 2012 in Physical Review Letters
ABSTRACT
PUBLICATION RECORD
- Publication year
2012
- Venue
Physical Review Letters
- Publication date
2012-04-03
- Fields of study
Biology, Materials Science, Medicine, Physics
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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