Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Mechanisms of Development

• Publication date

  1997-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0925-4773(97)00052-XPMID 9232600
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1996cited by this paper
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  1996cited by this paper
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• 14-3-3 and its possible role in co-ordinating multiple signalling pathways.

  1996cited by this paper
• The activity of D-raf in torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting.

  1996cited by this paper
• Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1.

  1996cited by this paper
• Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling.

  1996cited by this paper
• Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine.

  1996cited by this paper
• Inhibition of Raf/MAPK signaling in Xenopus oocyte extracts by Raf-1-specific peptides.

  1996cited by this paper
• Oligomerization activates c-Raf-1 through a Ras-dependent mechanism

  1996cited by this paper
• Mechanisms regulating Raf‐1 activity in signal transduction pathways

  1995cited by this paper
• KSR, a novel protein kinase required for RAS signal transduction.

  1995cited by this paper
• The ksr-7 Gene Encodes a Novel Protein Kinase Involved in Ras-Mediated Signaling in C. elegans

  1995cited by this paper
• Bcr and Raf form a complex in vivo via 14‐3‐3 proteins.

  1995cited by this paper
• Regulation of Raf‐1 kinase activity by the 14‐3‐3 family of proteins.

  1995cited by this paper
• Ras recruits Raf‐1 to the plasma membrane for activation by tyrosine phosphorylation.

  1995cited by this paper
• 14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner

  1995cited by this paper
• 14-3-3 alpha and delta are the phosphorylated forms of raf-activating 14-3-3 beta and zeta. In vivo stoichiometric phosphorylation in brain at a Ser-Pro-Glu-Lys MOTIF.

  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Regulation of Raf-1 and Raf-1 mutants by Ras-dependent and Ras-independent mechanisms in vitro

  1995cited by this paper
• Nuclear factors in sevenless signalling.

  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• The MAPK signaling cascade

  1995cited by this paper
• Lack of evidence for the activation of the Ras/Raf mitogenic pathway by 14-3-3 proteins in mammalian cells.

  1995cited by this paper
• Reversal of Raf-1 activation by purified and membrane-associated protein phosphatases.

  1995cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
• Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase.

  1993cited by this paper
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  1993cited by this paper
• Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system.

  1993cited by this paper
• Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

  1993cited by this paper
• Protein kinase C alpha activates RAF-1 by direct phosphorylation.

  1993cited by this paper
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  1993cited by this paper
• Activation of the MAP kinase pathway by the protein kinase raf.

  1992cited by this paper
• 14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins.

  1992cited by this paper
• The role of Raf-1 phosphorylation in signal transduction.

  1992cited by this paper
• Raf functions downstream of Rasl in the Sevenless signal transduction pathway

  1992cited by this paper
• Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells

  1992cited by this paper
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  1992cited by this paper
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  1991cited by this paper
• The spatial and temporal expression pattern of sevenless is exclusively controlled by gene‐internal elements.

  1989cited by this paper
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  1988cited by this paper
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  1987cited by this paper
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  1984cited by this paper

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  2005cites this paper
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  2005cites this paper
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