Sumo in development: lessons from drosophila with comparisons to mammals

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology

• Identifiers
  DOI 10.15761/gtgd.1000102
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• The SUMO-targeted ubiquitin ligase, Dgrn, is essential for Drosophila innate immunity.

  2017cited by this paper
• Genome Regulation by Polycomb and Trithorax: 70 Years and Counting.

  2017cited by this paper
• RAS GTPases are modified by SUMOylation

  2017cited by this paper
• SUMO wrestling with Ras

  2016cited by this paper
• Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

  2015cited by this paper
• Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9

  2015cited by this paper
• A new world of Polycombs: unexpected partnerships and emerging functions

  2013influential reference
• Negative Regulation of TLR Inflammatory Signaling by the SUMO-deconjugating Enzyme SENP6

  2013cited by this paper
• Regulation of Toll Signaling and Inflammation by β-Arrestin and the SUMO Protease Ulp1

  2013cited by this paper
• SUMOylation in Drosophila Development

  2012cited by this paper
• Groucho: a corepressor with instructive roles in development.

  2012influential reference
• Ubc9 negatively regulates BMP-mediated osteoblastic differentiation in cultured cells.

  2012cited by this paper
• Degringolade, a SUMO‐targeted ubiquitin ligase, inhibits Hairy/Groucho‐mediated repression

  2011cited by this paper
• Emerging roles of the SUMO pathway in development

  2011cited by this paper
• Crosstalk between JNK and SUMO Signaling Pathways: deSUMOylation Is Protective against H2O2-Induced Cell Injury

  2011cited by this paper
• Regulation of Drosophila lifespan by JNK signaling.

  2011influential reference
• Drosophila Smt3 negatively regulates JNK signaling through sequestering Hipk in the nucleus

  2011cited by this paper
• Small Ubiquitin-like Modifier (SUMO) Conjugation Impedes Transcriptional Silencing by the Polycomb Group Repressor Sex Comb on Midleg*

  2011influential reference
• Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation

  2011cited by this paper
• Control of nuclear HIPK2 localization and function by a SUMO interaction motif.

  2011cited by this paper
• SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development.

  2010cited by this paper
• β‐arrestin Kurtz inhibits MAPK and Toll signalling in Drosophila development

  2010cited by this paper
• Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling

  2009cited by this paper
• Covalent conjugation of Groucho with SUMO-1 modulates its corepressor activity.

  2009cited by this paper
• Graded dorsal and differential gene regulation in the Drosophila embryo.

  2009cited by this paper
• Genetic and Proteomic Evidence for Roles of Drosophila SUMO in Cell Cycle Control, Ras Signaling, and Early Pattern Formation

  2009cited by this paper
• Innate immunity in Drosophila: Pathogens and pathways

  2008cited by this paper
• Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo.

  2008cited by this paper
• Human Polycomb 2 Protein Is a SUMO E3 Ligase and Alleviates Substrate-Induced Inhibition of Cystathionine β-Synthase Sumoylation

  2008cited by this paper
• SUMO junction—what's your function?

  2007cited by this paper
• Foxo and Fos regulate the decision between cell death and survival in response to UV irradiation

  2007cited by this paper
• Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance.

  2007cited by this paper
• Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2.

  2006cited by this paper
• Specification of SUMO1- and SUMO2-interacting Motifs*

  2006cited by this paper
• Faculty Opinions recommendation of Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo.

  2005cited by this paper
• Crystal structure of thymine DNA glycosylase conjugated to SUMO-1

  2005cited by this paper
• Regulation of Homeodomain-interacting Protein Kinase 2 (HIPK2) Effector Function through Dynamic Small Ubiquitin-related Modifier-1 (SUMO-1) Modification*

  2005cited by this paper
• SUMO: a history of modification.

  2005cited by this paper
• Synaptic and genomic responses to JNK and AP-1 signaling in Drosophila neurons

  2005cited by this paper
• Argonaute—a database for gene regulation by mammalian microRNAs

  2005cited by this paper
• Repression of Smad4 transcriptional activity by SUMO modification.

  2004cited by this paper
• Requirement for Sex Comb on Midleg Protein Interactions in Drosophila Polycomb Group Repression

  2004cited by this paper
• The RAF proteins take centre stage

  2004cited by this paper
• SUMO modification is required for in vivo Hox gene regulation by the Caenorhabditis elegans Polycomb group protein SOP-2

  2004cited by this paper
• Identification of a SUMO-binding motif that recognizes SUMO-modified proteins.

  2004cited by this paper
• Drosophila Ulp1, a Nuclear Pore-associated SUMO Protease, Prevents Accumulation of Cytoplasmic SUMO Conjugates*

  2004cited by this paper
• Sumoylation of Smad4, the Common Smad Mediator of Transforming Growth Factor-β Family Signaling*

  2003cited by this paper
• Rasl and a Putative Guanine Nucleotide Exchange Factor Perform Crucial Steps in Signaling by the Sevenless Protein Tyrosine Kinase

  2003cited by this paper
• Activation of Transforming Growth Factor-β Signaling by SUMO-1 Modification of Tumor Suppressor Smad4/DPC4*

  2003cited by this paper
• The nucleoporin RanBP2 has SUMO1 E3 ligase activity.

  2002cited by this paper
• 14-3-3 Antagonizes Ras-Mediated Raf-1 Recruitment to the Plasma Membrane To Maintain Signaling Fidelity

  2002cited by this paper
• Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

  2002cited by this paper
• Conjugation of Smt3 to Dorsal May Potentiate the Drosophila Immune Response

  2002cited by this paper
• Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis.

  2001cited by this paper
• Nuclear interpretation of Dpp signaling in Drosophila

  2001cited by this paper
• SUMO-1 Conjugation in Vivo Requires Both a Consensus Modification Motif and Nuclear Targeting*

  2001cited by this paper
• Brinker requires two corepressors for maximal and versatile repression in Dpp signalling

  2001influential reference
• Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation*

  2000cited by this paper
• Structure determination of the small ubiquitin-related modifier SUMO-1.

  1998cited by this paper
• Conversion of dorsal from an activator to a repressor by the global corepressor Groucho.

  1997influential reference
• Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo.

  1997cited by this paper
• Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed.

  1997influential reference
• Differential activity of Ras1 during patterning of the Drosophila dorsoventral axis.

  1996cited by this paper
• Activated Ras displaces 14-3-3 protein from the amino terminus of c-Raf-1.

  1996cited by this paper
• Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila.

  1996cited by this paper
• Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.

  1995cited by this paper
• A processed form of the Spätzle protein defines dorsal-ventral polarity in the Drosophila embryo.

  1994cited by this paper
• Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins.

  1994influential reference
• Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis.

  1994cited by this paper
• A temperature-sensitive MEK mutation demonstrates the conservation of the signaling pathways activated by receptor tyrosine kinases.

  1994cited by this paper
• The spätzle gene encodes a component of the extracellular signaling pathway establishing the dorsal-ventral pattern of the Drosophila embryo.

  1994cited by this paper
• Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

  1994cited by this paper
• An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro.

  1993cited by this paper
• SH2 and SH3 domains: from structure to function.

  1992cited by this paper
• The Son of sevenless gene product: a putative activator of Ras.

  1992cited by this paper
• cactus, a maternal gene required for proper formation of the dorsoventral morphogen gradient in Drosophila embryos.

  1991cited by this paper
• Zygotic expression and activity of the Drosophila Toll gene, a gene required maternally for embryonic dorsal-ventral pattern formation.

  1988cited by this paper

• Profiling Substrate Specificity of the SUMO Protease Ulp1 by the YESS–PSSC System to Advance the Conserved Mechanism for Substrate Cleavage

  2022cites this paper