Progression of early structural lung disease in young children with cystic fibrosis assessed using CT

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Thorax

• Publication date

  2011-12-26

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1136/thoraxjnl-2011-200912PMID 22201161
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inflammatory responses to individual microorganisms in the lungs of children with cystic fibrosis.

  2011cited by this paper
• Association between genotype and pulmonary phenotype in cystic fibrosis patients with severe mutations.

  2011cited by this paper
• Exciting new clinical trials in cystic fibrosis: infants need not apply.

  2011cited by this paper
• Mutations that permit residual CFTR function delay acquisition of multiple respiratory pathogens in CF patients

  2010cited by this paper
• Lung Disease at Diagnosis in Infants with Cystic Fibrosis Detected by Newborn Screening

  2010cited by this paper
• Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening.

  2009influential reference
• Bronchiectasis in infants and preschool children diagnosed with cystic fibrosis after newborn screening.

  2009influential reference
• Cystic fibrosis genotype and assessing rates of decline in pulmonary status.

  2009cited by this paper
• Acquisition and eradication of P. aeruginosa in young children with cystic fibrosis

  2008cited by this paper
• Computed tomography reflects lower airway inflammation and tracks changes in early cystic fibrosis.

  2007cited by this paper
• Correlation of forced oscillation technique in preschool children with cystic fibrosis with pulmonary inflammation

  2005cited by this paper
• Comparison of quiet breathing and controlled ventilation in the high-resolution CT assessment of airway disease in infants with cystic fibrosis

  2005cited by this paper
• High-resolution computed tomography imaging of airway disease in infants with cystic fibrosis.

  2005cited by this paper
• Dose reduction for CT in children with cystic fibrosis: is it feasible to reduce the number of images per scan?

  2005cited by this paper
• High-resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalities and correlation with pulmonary function tests.

  2004cited by this paper
• Structural airway abnormalities in infants and young children with cystic fibrosis.

  2004cited by this paper
• Reversible bronchial dilatation in children: comparison of serial high-resolution computer tomography scans of the lungs.

  2003cited by this paper
• Effect of genotype on phenotype and mortality in cystic fibrosis: a retrospective cohort study.

  2003cited by this paper
• Molecular consequences of cystic fibrosis transmembrane regulator (CFTR) gene mutations in the exocrine pancreas

  2003cited by this paper
• The Phenotypic Consequences of CFTR Mutations

  2003cited by this paper
• The cystic fibrosis transmembrane conductance regulator: an intriguing protein with pleiotropic functions.

  2002cited by this paper
• Genotype and Phenotype in Cystic Fibrosis

  2000cited by this paper
• Cystic fibrosis clinical score: a new scoring system to evaluate acute pulmonary exacerbation.

  1999cited by this paper
• Correlation of sweat chloride concentration with classes of the cystic fibrosis transmembrane conductance regulator gene mutations.

  1995cited by this paper
• Cystic fibrosis: genotypic and phenotypic variations.

  1995cited by this paper
• No Adjustments Are Needed for Multiple Comparisons

  1990cited by this paper

• Feasibility and Utility of Multiple Breath Washout Measured Scond and Sacin in Preschool Children With Cystic Fibrosis

  2025cites this paper
• Normative values for lung, bronchial sizes, and bronchus-artery ratios in chest CT scans: from infancy into young adulthood

  2025cites this paper
• The bad bug: early MRSA infections in children with CF are associated with worse respiratory outcomes.

  2025cites this paper
• Pseudomonas aeruginosa increases viscoelasticity and decreases transportability of artificial mucus

  2025cites this paper
• Ultralow dose computed tomography as an alternative to conventional chest radiography for the evaluation of disease severity in paediatric cystic fibrosis

  2025cites this paper
• A Systematic Review of the Variability of Ventilation Defect Percent Generated From Hyperpolarized Noble Gas Pulmonary Magnetic Resonance Imaging

  2025cites this paper
• Pulmonary endpoints in clinical trials for children with cystic fibrosis under two years of age.

  2025cites this paper
• Federated Learning: A new frontier in the exploration of multi-institutional medical imaging data

  2025cites this paper
• Reversal of cylindrical bronchial dilatations in a subset of adults with cystic fibrosis treated with elexacaftor/tezacaftor/ivacaftor

  2024cites this paper
• Paediatric Thoracic Imaging in Cystic Fibrosis in the Era of Cystic Fibrosis Transmembrane Conductance Regulator Modulation

  2024cites this paper
• Cystic fibrosis foundation position paper: Redefining the CF care model.

  2024cites this paper
• Therapeutic improvement of CFTR function and reversibility of bronchiectasis in cystic fibrosis

  2024cites this paper
• Point of care lung ultrasound in preschool children with cystic fibrosis: a case-controlled, prospective, pilot study

  2024cites this paper
• Hierarchical CT Scoring Systems Cannot Discriminate Between Reversible Bronchiectasis and Mucus Plugs.

  2024cites this paper
• Impact of age at ivacaftor initiation on pulmonary outcomes among people with cystic fibrosis

  2024cites this paper
• Longitudinal Magnetic Resonance Imaging of Changes in Lung Morphology and Perfusion in Children with Cystic Fibrosis From Infancy through Adolescence.

  2024cites this paper
• Revisiting Host-Pathogen Interactions in Cystic Fibrosis Lungs in the Era of CFTR Modulators

  2023cites this paper
• TRACK-CF prospective cohort study: Understanding early cystic fibrosis lung disease

  2023cites this paper
• Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial

  2023cites this paper
• Substrate-dependent metabolomic signatures of myeloperoxidase activity in airway epithelial cells: Implications for early cystic fibrosis lung disease.

  2023cites this paper
• The effect of CFTR modulators on structural lung disease in cystic fibrosis

  2023cites this paper
• Endobronchial optical coherence tomography or computed tomography for evaluating progression of bronchiectasis

  2023cites this paper
• The clinical impact of Lumacaftor-Ivacaftor on structural lung disease and lung function in children aged 6–11 with cystic fibrosis in a real-world setting

  2023cites this paper
• Comparative sensitivity of Early Cystic Fibrosis Lung Disease detection tools in school aged children

  2023cites this paper
• MDCT-based longitudinal automated airway and air trapping analysis in school-age children with mild cystic fibrosis lung disease

  2023cites this paper
• Automatic analysis of bronchus-artery dimensions to diagnose and monitor airways disease in cystic fibrosis

  2023cites this paper
• What Is Most Suitable for Children With Cystic Fibrosis—The Relationship Between Spirometry, Oscillometry, and Multiple Breath Nitrogen Washout

  2022cites this paper
• Early Pseudomonas aeruginosa predicts poorer pulmonary function in preschool children with cystic fibrosis.

  2022cites this paper
• Cystic fibrosis in the 21st century: what every radiologist should know.

  2022cites this paper
• Mucus and mucus flake composition and abundance reflect inflammatory and infection status in cystic fibrosis.

  2022cites this paper
• State-of-the-art review of lung imaging in cystic fibrosis with recommendations for pulmonologists and radiologists from the “iMAging managEment of cySTic fibROsis” (MAESTRO) consortium

  2022cites this paper
• Pilot study of inflammatory biomarkers in matched induced sputum and bronchoalveolar lavage of 2‐year‐olds with cystic fibrosis

  2022cites this paper
• The Changing Face of Cystic Fibrosis: An Update for Anesthesiologists.

  2022cites this paper
• The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial.

  2022cites this paper
• Computed tomography in cystic fibrosis lung disease: a focus on radiation exposure

  2021cites this paper
• Correction of sensor crosstalk error in Exhalyzer D multiple-breath washout device significantly impacts outcomes in children with cystic fibrosis.

  2021cites this paper
• Changes in airway inflammation with pseudomonas eradication in early cystic fibrosis.

  2021cites this paper
• Early Diagnosis and Intervention in Cystic Fibrosis: Imagining the Unimaginable

  2021cites this paper
• Could automated analysis of chest X-rays detect early bronchiectasis in children?

  2021cites this paper
• Determinants of lung disease progression measured by lung clearance index in children with cystic fibrosis

  2021cites this paper
• Perspectives on the translation of in-vitro studies to precision medicine in Cystic Fibrosis

  2021cites this paper
• Ivacaftor Reduces Inflammatory Mediators in Upper Airway Lining Fluid From Cystic Fibrosis Patients With a G551D Mutation: Serial Non-Invasive Home-Based Collection of Upper Airway Lining Fluid

  2021cites this paper
• Recent advances in the early treatment of cystic fibrosis: Bridging the gap to highly effective modulator therapy

  2021cites this paper
• The feasibility of home monitoring of young people with cystic fibrosis: Results from CLIMB-CF.

  2021cites this paper
• Time to get serious about the detection and monitoring of early lung disease in cystic fibrosis

  2021cites this paper
• Functional respiratory imaging in relation to classical outcome measures in cystic fibrosis: a cross-sectional study

  2021cites this paper
• Early surveillance of infants and preschool children with cystic fibrosis

  2021cites this paper
• Postnatal Ozone Exposure Disrupts Alveolar Development, Exaggerates Mucoinflammatory Responses, and Suppresses Bacterial Clearance in Developing Scnn1b-Tg+ Mice Lungs

  2021cites this paper
• Quantification of Phenotypic Variability of Lung Disease in Children with Cystic Fibrosis

  2021cites this paper
• Defect distribution index: A novel metric for functional lung MRI in cystic fibrosis

  2021cites this paper
• Antisense Oligonucleotide Therapy to Correct CFTR Function in People with Cystic Fibrosis

  2021cites this paper
• Magnetic Resonance Imaging Detects Progression of Lung Disease and Impact of Newborn Screening in Preschool Children with Cystic Fibrosis.

  2021cites this paper
• Pseudomonas aeruginosa Isolates From a Cohort of Mexican Children With Cystic Fibrosis Show Adaptation to a Chronic Phenotype

  2020cites this paper
• Lung and Pleura

  2020cites this paper
• Neonatal screening programme for CF: Results from the Irish Comparative Outcomes Study (ICOS)

  2020cites this paper
• Anti-inflammatory effects of lenabasum, a cannabinoid receptor type 2 agonist, on macrophages from cystic fibrosis.

  2020cites this paper
• Structural determinants of long-term functional outcomes in young children with cystic fibrosis

  2020cites this paper
• Lung T1 mapping magnetic resonance imaging in the assessment of pulmonary disease in children with cystic fibrosis: a pilot study

  2020cites this paper
• The Detection of Bile Acids in the Lungs of Paediatric Cystic Fibrosis Patients Is Associated with Altered Inflammatory Patterns

  2020cites this paper
• Effect of Inspiratory Maneuvers on Lung Deposition of Tobramycin Inhalation Powder: A Modeling Study

  2020cites this paper
• Early Cystic Fibrosis Lung Disease

  2020cites this paper
• Functional Assessment of Cystic Fibrosis Lung Disease

  2020cites this paper
• Minimal structural lung disease in early life represents significant pathology.

  2020cites this paper
• Pulmonary function evaluation in pediatric patients with primary immunodeficiency complicated by bronchiectasis.

  2020cites this paper
• Utility of lung clearance index in CF: What we know, what we don't know and musings on how to bridge the gap.

  2020cites this paper
• Glycoprotein A as a biomarker of pulmonary infection and inflammation in children with cystic fibrosis

  2020cites this paper
• Bile Acid Signal Molecules Associate Temporally with Respiratory Inflammation and Microbiome Signatures in Clinically Stable Cystic Fibrosis Patients

  2020cites this paper
• Risk factors for progression of structural lung disease in school-age children with cystic fibrosis.

  2020cites this paper
• Prospective longitudinal association between repeated multiple breath washout measurements and computed tomography scores in children with cystic fibrosis.

  2020cites this paper
• Genomic Diversity and Antimicrobial Resistance of Haemophilus Colonizing the Airways of Young Children with Cystic Fibrosis

  2020cites this paper
• From micro to macro; joining the dots of early CF lung disease.

  2020cites this paper
• Microbiomic Analysis on Low Abundant Respiratory Biomass Samples; Improved Recovery of Microbial DNA From Bronchoalveolar Lavage Fluid

  2020cites this paper
• The impact of chest computed tomography and chest radiography on clinical management of cystic fibrosis lung disease.

  2020cites this paper
• Assessment of early lung disease in young children with CF: A comparison between pressure‐controlled and free‐breathing chest computed tomography

  2020cites this paper
• Guidance for computed tomography (CT) imaging of the lungs for patients with cystic fibrosis (CF) in research studies.

  2020cites this paper
• Designing Clinical Trials for Anti-Inflammatory Therapies in Cystic Fibrosis

  2020cites this paper
• Cystic fibrosis in the year 2020: A disease with a new face

  2020cites this paper
• An 8 week open-label interventional multicenter study to explore the lung clearance index as endpoint for clinical trials in cystic fibrosis patients ≥8 years of age, chronically infected with Pseudomonas aeruginosa

  2020cites this paper
• Computertomographie der Lunge bei Mukoviszidose

  2020cites this paper
• Impact of Pseudomonas aeruginosa Infection on Patients with Chronic Inflammatory Airway Diseases

  2020cites this paper
• [Cystic fibrosis and computed tomography of the lungs].

  2020cites this paper
• Ivacaftor in Infants Aged 4 to <12 Months with Cystic Fibrosis and a Gating Mutation. Results of a Two-Part Phase 3 Clinical Trial

  2020cites this paper
• The future of cystic fibrosis care: a global perspective.

  2020cites this paper
• Acute pulmonary exacerbation in cystic fibrosis

  2020cites this paper
• LUNG CLEARANCE INDEX – USEFUL PARAMETER FOR ASSESSING LUNG FUNCTION IN CYSTIC FIBROSIS CHILDREN

  2019cites this paper
• Letting It All Out: Neutrophils in Early Cystic Fibrosis Airway Inflammation

  2019cites this paper
• The evolution of lung function in newborn screened preschool children with cystic fibrosis

  2019cites this paper
• Elastase Exocytosis by Airway Neutrophils Is Associated with Early Lung Damage in Children with Cystic Fibrosis

  2019cites this paper
• Eradication of early P. aeruginosa infection in children <7 years of age with cystic fibrosis: The early study.

  2019cites this paper
• Progression of Cystic Fibrosis Lung Disease from Childhood to Adulthood: Neutrophils, Neutrophil Extracellular Trap (NET) Formation, and NET Degradation

  2019cites this paper
• Single‐breath washout and association with structural lung disease in children with cystic fibrosis

  2019cites this paper
• Regional differences in infection and structural lung disease in infants and young children with cystic fibrosis.

  2019cites this paper
• Current state of the art MRI for the longitudinal assessment of cystic fibrosis

  2019cites this paper
• Pediatric Thoracic MRI

  2019cites this paper
• Acute Pulmonary Exacerbations in Cystic Fibrosis

  2019cites this paper
• Pulmonary Disease in Cystic Fibrosis

  2019cites this paper
• The Evaluation of Lung Involvement in Patients with Cystic Fibrosis by Using Mediastinal Magnetic Resonance Imaging

  2019cites this paper
• Pediatric Pulmonology

  2019cites this paper
• The role of geographical location and climate on recurrent Pseudomonas infection in young children with Cystic Fibrosis.

  2019cites this paper
• Airway microenvironment alterations and pathogen growth in cystic fibrosis

  2019cites this paper