Corticotropin tests for hypothalamic-pituitary- adrenal insufficiency: a metaanalysis.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Clinical Endocrinology and Metabolism

• Publication date

  2008-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1210/jc.2008-0710PMID 18697868
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1994cited by this paper
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  1978cited by this paper
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  1965cited by this paper

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